DOI QR코드

DOI QR Code

Primary xanthoma inferior to the right mandibular third molar and intraoral vertical ramus osteotomy

  • Kim, Min-Ji (Department of Oral and Maxillofacial Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Kang, Min-Jun (Department of Oral and Maxillofacial Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Kang, Sang-Hoon (Department of Oral and Maxillofacial Surgery, National Health Insurance Service Ilsan Hospital)
  • Received : 2021.12.20
  • Accepted : 2022.03.09
  • Published : 2022.06.30

Abstract

Intraosseous xanthoma of the mandible is a rare benign disorder. A 17-year-old male patient presented with a suspected abscess in the right mandibular third molar, detected on a panoramic radiograph. The patient had no history of systemic or lipid-related metabolic diseases and complained of no specific symptoms or pain. A radiographic examination revealed a heterogeneous radiolucency extending from the apical to the distal aspect of the right mandibular third molar tooth germ. The lesion measured 9 × 16 × 24 mm (antero-posterior × mediolateral × supero-inferior) and showed a relatively well-defined, multilocular, foamy appearance with hyperostotic borders spreading to the inferior alveolar nerve canal. After excisional biopsy, a diagnosis of central xanthoma was made. The lesion recurred, and intraoral vertical ramus osteotomy was done near the lesion. For the treatment of xanthoma of the mandible, extensive and delicate surgical treatment under general anesthesia should be considered.

Keywords

References

  1. Huang GS, Huang CW, Lee CH, Taylor JA, Lin CG, Chen CY. Xanthoma of the sacrum. Skeletal Radiol 2004; 33: 674-8. https://doi.org/10.1007/s00256-004-0829-z
  2. Marques Mateo M, Puche Torres M, Miragall Alba L, Iglesias Gimilio ME, Pascual Gil JV. Primary mandibular bone xanthoma. A case report. Int J Oral Maxillofac Surg 2004; 33: 806-7. https://doi.org/10.1016/j.ijom.2003.12.006
  3. Reuben A. The serology of the Addison-Gull syndrome. Hepatology 2003; 37: 225-8. https://doi.org/10.1002/hep.510370134
  4. Bonhomme GR, Loevner LA, Yen DM, Deems DA, Bigelow DC, Mirza N. Extensive intracranial xanthoma associated with type II hyperlipidemia. AJNR Am J Neuroradiol 2000; 21: 353-5.
  5. Brooks JK, Mostoufi B, Sultan AS, Khoury ZH, Price JB, Papadimitriou JC, et al. Central xanthoma of the mandible associated with hyperlipidemia: a rare presentation. Int J Pediatr Otorhinolaryngol 2018; 105: 75-8. https://doi.org/10.1016/j.ijporl.2017.11.028
  6. de Moraes Ramos-Perez FM, de Padua JM, Silva-Sousa YT, de Almeida OP, da Cruz Perez DE. Primary xanthoma of the mandible. Dentomaxillofac Radiol 2011; 40: 393-6. https://doi.org/10.1259/dmfr/51850495
  7. Rawal YB, Chandra SR, Hall JM. Central xanthoma of the jaw bones: a benign tumor. Head Neck Pathol 2017; 11: 192-202. https://doi.org/10.1007/s12105-016-0764-z
  8. Slootweg PJ, Swart JG, van Kaam N. Xanthomatous lesion of the mandible. Report of a case. Int J Oral Maxillofac Surg 1993; 22: 236-7. https://doi.org/10.1016/S0901-5027(05)80644-7
  9. Saha A, Tocaciu S, Subramanian B. Primary xanthoma of the mandible - a case report. J Oral Maxillofac Surg 2018; 76: 374 e1-4. https://doi.org/10.1016/j.joms.2017.10.009
  10. de Araujo MR, Scariot R, Uetanabaro L, Luvison Gomes da Silva L, Giovanini AF. Primary mandibular xanthoma: case report. Oral Surg Oral Med Oral Pathol Oral Radiol 2015; 120: e177-82. https://doi.org/10.1016/j.oooo.2015.01.015
  11. de Arruda JA, Almeida TF, Abreu LG, do Amaral MB, Anbinder AL, Flores RM, et al. Intraosseous xanthoma of the mandible: a multi-institutional case series with a literature review. J Oral Pathol Med 2019; 48: 935-42. https://doi.org/10.1111/jop.12940
  12. Morel D, Kelsch RD, Nolan PJ. Primary xanthoma of the mandible: report of a rare case. Head Neck Pathol 2016; 10: 245-51. https://doi.org/10.1007/s12105-015-0643-z
  13. Wilkinson PE, Merkourea S, Gopalakrishnan R, Argyris PP. Primary intraosseous xanthomas of the jaws: a series of six cases including an example with formation of apoptosis-related hyaline globules, so-called "Thanatosomes". Head Neck Pathol 2020; 14: 859-68. https://doi.org/10.1007/s12105-020-01126-2
  14. Cooper TJ, Lincoln T, James DT, Borgna S. Intraosseous spindle cell lipoma of the mandible: case report. Br J Oral Maxillofac Surg 2017; 55: 839-40. https://doi.org/10.1016/j.bjoms.2017.06.015
  15. Harsanyi BB, Larsson A. Xanthomatous lesions of the mandible: osseous expression of non-X histiocytosis and benign fibrous histiocytoma. Oral Surg Oral Med Oral Pathol 1988; 65: 551-66. https://doi.org/10.1016/0030-4220(88)90138-7
  16. Bertoni F, Unni KK, McLeod RA, Sim FH. Xanthoma of bone. Am J Clin Pathol 1988; 90: 377-84. https://doi.org/10.1093/ajcp/90.4.377
  17. Dallari D, Marinelli A, Pellacani A, Valeriani L, Lesi C, Bertoni F, et al. Xanthoma of bone: first sign of hyperlipidemia type IIB: a case report. Clin Orthop Relat Res 2003; 410: 274-7. https://doi.org/10.1097/01.blo.0000063790.32430.10