Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
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Botulinum Toxin Injection Therapy for Lingual Dystonia: A Case Report

  • Bae, So-Yeon (Department of Oral Medicine, School of Dentistry, Kyungpook National University) ;
  • Kim, Ji-Rak (Department of Oral Medicine, School of Dentistry, Kyungpook National University)
  • Received : 2022.08.23
  • Accepted : 2022.09.02
  • Published : 2022.09.30
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Abstract

Lingual dystonia is an uncommon focal type of oromandibular dystonia that only affects the tongue. Although the use of several treatment modalities has been attempted to reduce involuntary tongue movements, such as anticonvulsants and anticholinergics, the results do not seem promising, and the efficacy of such treatments is unpredictable among patients. This case report describes botulinum toxin injection for a patient with lingual dystonia with favorable clinical results. Botulinum toxin injection to the muscles of the tongue could be an alternative treatment option for lingual dystonia.

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References

  1. Albanese A, Bhatia K, Bressman SB, et al. Phenomenology and classification of dystonia: a consensus update. Mov Disord 2013;28:863-873. https://doi.org/10.1002/mds.25475
  2. Yoshida K. Botulinum neurotoxin therapy for lingual dystonia using an individualized injection method based on clinical features. Toxins (Basel) 2019;11:51. https://doi.org/10.3390/toxins11010051
  3. Yousafzai ZA, Qayyum W, Khan S, Iftikhar M, Amin QK. Case report: isolated lingual dystonia. F1000Res 2020;9:314. https://doi.org/10.12688/f1000research.23237.1
  4. Britton D, Alty JE, Mannion CJ. Oromandibular dystonia: a diagnosis not to miss. Br J Oral Maxillofac Surg 2020;58:520-524. https://doi.org/10.1016/j.bjoms.2020.02.018
  5. Nutt JG, Muenter MD, Aronson A, Kurland LT, Melton LJ 3rd. Epidemiology of focal and generalized dystonia in Rochester, Minnesota. Mov Disord 1988;3:188-194. https://doi.org/10.1002/mds.870030302
  6. Raoofi S, Khorshidi H, Najafi M. Etiology, diagnosis and management of oromandibular dystonia: an update for stomatologists. J Dent (Shiraz) 2017;18:73-81.
  7. Esper CD, Freeman A, Factor SA. Lingual protrusion dystonia: frequency, etiology and botulinum toxin therapy. Parkinsonism Relat Disord 2010;16:438-441. https://doi.org/10.1016/j.parkreldis.2010.04.007
  8. Termsarasab P, Thammongkolchai T, Frucht SJ. Medical treatment of dystonia. J Clin Mov Disord 2016;3:19. Erratum in: J Clin Mov Disord 2018;5:8. https://doi.org/10.1186/s40734-018-0075-5
  9. Budak F, Aydin E, Kockaya A, Ilbay G. Botulinum toxin in the treatment of lingual dystonia induced by speaking. Case Rep Neurol 2013;5:18-20. https://doi.org/10.1159/000347000
  10. Hennings JM, Krause E, Botzel K, Wetter TC. Successful treatment of tardive lingual dystonia with botulinum toxin: case report and review of the literature. Prog Neuropsychopharmacol Biol Psychiatry 2008;32:1167-1171. https://doi.org/10.1016/j.pnpbp.2007.09.010
  11. Nigam PK, Nigam A. Botulinum toxin. Indian J Dermatol 2010;55:8-14. https://doi.org/10.4103/0019-5154.60343
  12. Nastasi L, Mostile G, Nicoletti A, Zappia M, Reggio E, Catania S. Effect of botulinum toxin treatment on quality of life in patients with isolated lingual dystonia and oromandibular dystonia affecting the tongue. J Neurol 2016;263:1702-1708. https://doi.org/10.1007/s00415-016-8185-1