Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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The healing pattern of a 4 mm proximal infrabony defect was not significantly different from a 2 mm defect adjacent to dental implant in a canine mandible

  • An, Min Kuk (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Kim, Hyun Ju (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Choi, Jin Uk (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Kim, Kyoung-Hwa (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Lee, Yong-Moo (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Rhyu, In-Chul (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Seol, Yang-Jo (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University)
  • Received : 2021.12.16
  • Accepted : 2022.04.20
  • Published : 2022.10.30
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Abstract

Purpose: The purpose of this study was to evaluate and compare the healing patterns of 2-mm and 4-mm proximal infrabony defects adjacent to dental implants in canine mandibles. Methods: Four male beagles were used. Two groups were created: a 2-mm group (n=4) and a 4-mm group (n=4) depending on the horizontal dimension of proximal infrabony defects adjacent to implants. Bone healing patterns between the 2 groups were evaluated and compared at 8 and 16 weeks using radiographic, histological, histomorphometric, and fluorescent labelling analyses. Results: According to microcomputed tomography, the median bone volume fraction, bone mineral density, and the percentage of radiographic distance from the defect bottom to the most coronal bone-to-implant contact (radio-mcBIC) were 32.9%, 0.6 g/cm3, and 73.7% (8 weeks) and 45.7%, 0.7 g/cm3, and 76.0% (16 weeks) in the 2-mm group and 57.7%, 0.8 g/cm3, and 75.7% (8 weeks) and 50.9%, 0.8 g/cm3, and 74.7% (16 weeks) in the 4-mm group, respectively. According to histomorphometry, the median bone area fraction, mcBIC and the percentage of BIC amounted to 36.7%, 3.4 mm, and 58.4% (8 weeks) and 49.2%, 3.4 mm, and 70.2% (16 weeks) in the 2-mm group and 50.0%, 3.0 mm, and 64.8% (8 weeks) and 55.7%, 3.0 mm, and 69.6% (16 weeks) in the 4-mm group, respectively. No statistically significant differences were found between the groups for any variables (P>0.05). Conclusions: The proximal defects that measured 2 mm and 4 mm showed similar healing patterns at 8 and 16 weeks, and the top of bone formation in the defects was substantially limited to a maximum of 1.6 mm below the implant shoulder in both groups.

Keywords

Acknowledgement

The authors thank Ms. Mi-Jung Kang for her excellent assistance.

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