Journal of Korean Dental Science

Korean Academy of Dental Science (대한치의학회)
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Antimicrobial Persistence of Silver Diamine Fluoride and Silver Fluoride against Streptococcus mutans

  • Hyeon-Jin Kim (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • So-Youn An (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University)
  • Received : 2023.06.13
  • Accepted : 2023.09.20
  • Published : 2023.12.30
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Abstract

Purpose: To evaluate the antimicrobial persistence of silver diamine fluoride (SDF) and silver fluoride (AgF) on Streptococcus mutans. Materials and Methods: An in vitro experiment was conducted to observe changes in the diameter of the inhibition zone of various materials, including AgF (Riva Star AquaTM step 1; SDI), potassium iodine (Riva star aquaTM step 2; SDI), Fluor protector® (FP, Ivoclar Vivadent), SDF (Riva starTM step 1; SDI), Ampicillin (Sigma-Aldrich), Amphotericin B (Nexstar) and negative control on S. mutans. Result: SDF, AgF and FP exhibited significant antimicrobial persistence over the 4 weeks period (P<0.05). At day 28, the diameter of inhibition zone was larger in SDF than in AgF. Conclusion: SDF and AgF have significant antibacterial durability against bacteria commonly associated with dental caries, with the antimicrobial effect lasting for at least 4 weeks. Further clinical studies are needed to validate these findings in vivo.

Keywords

Acknowledgement

This study was supported by Wonkwang University. This paper is the result of the scholarly activities of the Korean Dvosion of the International Association of Dental Research.

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