The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
권호 표지
DOI QR코드

DOI QR Code

An investigation of the relationship between cutaneous allodynia and kinesiophobia, gastrointestinal system symptom severity, physical activity and disability in individuals with migraine

  • Hafize, Altay (Physiotherapy and Rehabilitation Doctoral Program, Instute of Health Sciences, Ankara Yildirim Beyazit University) ;
  • Seyda Toprak, Celenay (Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Yildirim Beyazit University)
  • Received : 2022.09.30
  • Accepted : 2022.12.06
  • Published : 2023.01.01
Download PDF
⟨ Previous Next ⟩

Abstract

Background: To investigate the relationship between cutaneous allodynia (CA) and kinesiophobia, gastrointestinal system (GIS) symptom severity, physical activity, and disability, and to determine whether CA, pain, and disability were influencing factors for kinesiophobia, GIS symptoms, and physical activity in individuals with migraine. Methods: The study included 144 individuals with migraine. CA, kinesiophobia, GIS symptoms, physical activity level, and migraine-related disability were evaluated with the Allodynia Symptom Checklist, the Tampa Kinesiophobia Scale (TKS), the Gastrointestinal Symptom Rating Scale (GSRS), the International Physical Activity Questionnaire-7, and the Migraine Disability Assessment Scale (MIDAS), respectively. Results: The CA severity was only associated with TKS (r = 0.515; P < 0.001), GSRS-total (r = 0.336; P < 0.001), GSRS-abdominal pain (r = 0.323; P < 0.001), GSRS-indigestion (r = 0.257; P = 0.002), GSRS-constipation (r = 0.371; P < 0.001), and MIDAS scores (r = 0.178; P = 0.033). Attack frequency (P = 0.015), attack duration (P = 0.035) and presence of CA (P < 0.001) were risk factors for kinesiophobia. Attack frequency (P = 0.027) and presence of CA (P = 0.004) were risk factors for GIS symptoms. Conclusions: There was a relationship between the CA and kinesiophobia, GIS symptoms, and disability. CA and attack frequency were found to be risk factors for kinesiophobia and GIS symptoms. Migraine patients with CA should be assessed in terms of kinesiophobia, GIS, and disability. Lifestyle changes such as exercise and dietary changes and/or pharmacological treatment options for CA may increase success in migraine management.

Keywords

References

  1. Headache Classification Committee of the International Headache Society (IHS) the international classification of headache disorders, 3rd edition. Cephalalgia 2018; 38: 1-211. https://doi.org/10.1177/0333102417738202
  2. Stovner LJ, Hagen K, Jensen R, Katsarava Z, Lipton RB, Scher AI, et al. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 2007; 27: 193-210. https://doi.org/10.1111/j.1468-2982.2007.01288.x
  3. Chen PK, Wang SJ. Non-headache symptoms in migraine patients. F1000Res 2018; 7: 188. https://doi.org/10.12688/f1000research.12447.1
  4. Bigal ME, Ashina S, Burstein R, Reed ML, Buse D, Serrano D, et al. Prevalence and characteristics of allodynia in headache sufferers: a population study. Neurology 2008; 70: 1525-33. https://doi.org/10.1212/01.wnl.0000310645.31020.b1
  5. Burstein R, Yarnitsky D, Goor-Aryeh I, Ransil BJ, Bajwa ZH. An association between migraine and cutaneous allodynia. Ann Neurol 2000; 47: 614-24. https://doi.org/10.1002/1531-8249(200005)47:5<614::AID-ANA9>3.0.CO;2-N
  6. Celenay ST, Mete O, Coban O, Karahan N. [A comparison of pain severity, sleep quality, and psychological status between migraine patients with and without cutaneous allodynia]. Anatol Clin 2020; 25:102-7. Turkish. https://doi.org/10.21673/anadoluklin.644740
  7. Lipton RB, Bigal ME, Ashina S, Burstein R, Silberstein S, Reed ML, et al. Cutaneous allodynia in the migraine population. Ann Neurol 2008; 63: 148-58. https://doi.org/10.1002/ana.21211
  8. Kori SH, Miller RP, Todd DD. Kinisiophobia: a new view of chronic pain behavior. Pain Manage 1990; 3:35-43.
  9. McLean SA, Clauw DJ, Abelson JL, Liberzon I. The development of persistent pain and psychological morbidity after motor vehicle collision: integrating the potential role of stress response systems into a biopsychosocial model. Psychosom Med 2005; 67:783-90. https://doi.org/10.1097/01.psy.0000181276.49204.bb
  10. Benatto MT, Bevilaqua-Grossi D, Carvalho GF, Bragatto MM, Pinheiro CF, Straceri Lodovichi S, et al. Kinesiophobia is associated with migraine. Pain Med 2019; 20: 846-51. https://doi.org/10.1093/pm/pny206
  11. Chen X, D'Souza R, Hong ST. The role of gut microbiota in the gut-brain axis: current challenges and perspectives. Protein Cell 2013; 4: 403-14. https://doi.org/10.1007/s13238-013-3017-x
  12. Finkel AG, Yerry JA, Mann JD. Dietary considerations in migraine management: does a consistent diet improve migraine? Curr Pain Headache Rep 2013; 17: 373. https://doi.org/10.1007/s11916-013-0373-4
  13. Martami F, Ghorbani Z, Abolhasani M, Togha M, Meysamie A, Sharifi A, et al. Comorbidity of gastrointestinal disorders, migraine, and tension-type headache: a cross-sectional study in Iran. Neurol Sci 2018; 39: 63-70. https://doi.org/10.1007/s10072-017-3141-0
  14. Lankarani KB, Akbari M, Tabrizi R. Association of gastrointestinal functional disorders and migraine headache: a population base study. Middle East J Dig Dis 2017; 9: 139-45. https://doi.org/10.15171/mejdd.2017.64
  15. Tietjen GE, Brandes JL, Peterlin BL, Eloff A, Dafer RM, Stein MR, et al. Allodynia in migraine: association with comorbid pain conditions. Headache 2009; 49: 1333-44. https://doi.org/10.1111/j.1526-4610.2009.01521.x
  16. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep 1985; 100: 126-31.
  17. Wober C, Brannath W, Schmidt K, Kapitan M, Rudel E, Wessely P, et al. Prospective analysis of factors related to migraine attacks: the PAMINA study. Cephalalgia 2007; 27: 304-14. https://doi.org/10.1111/j.1468-2982.2007.01279.x
  18. Varkey E, Svealv BG, Edin F, Ravn-Fischer A, Cider A. Provocation of migraine after maximal exercise: a test-retest study. Eur Neurol 2017; 78: 22-7. https://doi.org/10.1159/000477166
  19. Martins IP, Gouveia RG, Parreira E. Kinesiophobia in migraine. J Pain 2006; 7: 445-51. https://doi.org/10.1016/j.jpain.2006.01.449
  20. Koppen H, van Veldhoven PL. Migraineurs with exercise-triggered attacks have a distinct migraine. J Headache Pain 2013; 14: 99. https://doi.org/10.1186/1129-2377-14-99
  21. Nijs J, Leysen L, Vanlauwe J, Logghe T, Ickmans K, Polli A, et al. Treatment of central sensitization in patients with chronic pain: time for change? Expert Opin Pharmacother 2019; 20: 1961-70. https://doi.org/10.1080/14656566.2019.1647166
  22. Renjith V, Pai MS, Castelino F, Pai A, George A. Clinical profile and functional disability of patients with migraine. J Neurosci Rural Pract 2016; 7: 250-6. https://doi.org/10.4103/0976-3147.176188
  23. Louter MA, Bosker JE, van Oosterhout WP, van Zwet EW, Zitman FG, Ferrari MD, et al. Cutaneous allodynia as a predictor of migraine chronification. Brain 2013; 136(Pt 11): 3489-96. https://doi.org/10.1093/brain/awt251
  24. Kwong WJ, Pathak DS. Validation of the eleven-point pain scale in the measurement of migraine headache pain. Cephalalgia 2007; 27: 336-42. https://doi.org/10.1111/j.1468-2982.2007.01283.x
  25. Yalin OO, Uluduz D, Sungur MA, Sart H, Ozge A. Identification of allodynic migraine patients with the Turkish version of the allodynia symptom checklist: reliability and consistency study. Noro Psikiyatr Ars 2017; 54: 260-6. https://doi.org/10.5152/npa.2016.15953
  26. Yilmaz OT, Yakut Y, Uygur F, Ulug N. [Turkish version of the Tampa Scale for Kinesiophobia and its test-retest reliability]. Fizyoter Rehabil 2011; 22: 44-9. Turkish.
  27. Branstrom H, Fahlstrom M. Kinesiophobia in patients with chronic musculoskeletal pain: differences between men and women. J Rehabil Med 2008; 40:375-80. https://doi.org/10.2340/16501977-0186
  28. Turan N, Asti TA, Kaya N. Reliability and validity of the Turkish version of the Gastrointestinal Symptom Rating Scale. Gastroenterol Nurs 2017; 40: 47-55. https://doi.org/10.1097/SGA.0000000000000177
  29. Saglam M, Arikan H, Savci S, Inal-Ince D, Bosnak-Guclu M, Karabulut E, et al. International physical activity questionnaire: reliability and validity of the Turkish version. Percept Mot Skills 2010; 111: 278-84. https://doi.org/10.2466/06.08.PMS.111.4.278-284
  30. Ertas M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache 2004; 44: 786-93. https://doi.org/10.1111/j.1526-4610.2004.04146.x
  31. Turk DC, Wilson HD. Fear of pain as a prognostic factor in chronic pain: conceptual models, assessment, and treatment implications. Curr Pain Headache Rep 2010; 14: 88-95. https://doi.org/10.1007/s11916-010-0094-x
  32. Crombez G, Vlaeyen JW, Heuts PH, Lysens R. Painrelated fear is more disabling than pain itself: evidence on the role of pain-related fear in chronic back pain disability. Pain 1999; 80: 329-39. https://doi.org/10.1016/S0304-3959(98)00229-2
  33. Cai L, Liu Y, Xu H, Xu Q, Wang Y, Lyu P. Incidence and risk factors of kinesiophobia after total knee arthroplasty in Zhengzhou, China: a cross-sectional study. J Arthroplasty 2018; 33: 2858-62. https://doi.org/10.1016/j.arth.2018.04.028
  34. Bilgin S, Cetin H, Karakaya J, Kose N. Multivariate analysis of risk factors predisposing to kinesiophobia in persons with chronic low back and neck pain. J Manipulative Physiol Ther 2019; 42: 565-71. https://doi.org/10.1016/j.jmpt.2019.02.009
  35. Aamodt AH, Stovner LJ, Hagen K, Zwart JA. Comorbidity of headache and gastrointestinal complaints. The Head-HUNT Study. Cephalalgia 2008; 28: 144-51. https://doi.org/10.1111/j.1468-2982.2007.01486.x
  36. Midenfjord I, Grinsvall C, Koj P, Carnerup I, Tornblom H, Simren M. Central sensitization and severity of gastrointestinal symptoms in irritable bowel syndrome, chronic pain syndromes, and inflammatory bowel disease. Neurogastroenterol Motil 2021; 33:e14156. https://doi.org/10.1111/nmo.14156
  37. Saberi HR, Moravveji AR. Gastrointestinal complaints in shift-working and day-working nurses in Iran. J Circadian Rhythms 2010; 8: 9. https://doi.org/10.1186/1740-3391-8-9
  38. Goyal O, Nohria S, Dhaliwal AS, Goyal P, Soni RK, Chhina RS, et al. Prevalence, overlap, and risk factors for Rome IV functional gastrointestinal disorders among college students in northern India. Indian J Gastroenterol 2021; 40: 144-53. https://doi.org/10.1007/s12664-020-01106-y
  39. Stronks DL, Tulen JH, Bussmann JB, Mulder LJ, Passchier J. Interictal daily functioning in migraine. Cephalalgia 2004; 24: 271-9. https://doi.org/10.1111/j.1468-2982.2004.00661.x
  40. Amin FM, Aristeidou S, Baraldi C, Czapinska-Ciepiela EK, Ariadni DD, Di Lenola D, et al. The association between migraine and physical exercise. J Headache Pain 2018; 19: 83. https://doi.org/10.1186/s10194-018-0902-y
  41. Seefeldt V, Malina RM, Clark MA. Factors affecting levels of physical activity in adults. Sports Med 2002; 32: 143-68. https://doi.org/10.2165/00007256-200232030-00001
  42. Burstein R, Jakubowski M, Rauch SD. The science of migraine. J Vestib Res 2011; 21: 305-14. https://doi.org/10.3233/VES-2012-0433
  43. Latremoliere A, Woolf CJ. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain 2009; 10: 895-926. https://doi.org/10.1016/j.jpain.2009.06.012
  44. Polk AN, Protti TA, Smitherman TA. Allodynia and disability in migraine: the mediating role of stress. Headache 2020; 60: 2281-90. https://doi.org/10.1111/head.14012