DOI QR코드

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ON THE ADAPTED EQUATIONS IN VARIOUS DYPLOID MODEL AND HARDY-WEINBURG EQUILIBRIUM IN A TRIPLOID MODEL

  • Won Choi (Department of Mathematics, Incheon National University)
  • 투고 : 2022.11.07
  • 심사 : 2023.01.02
  • 발행 : 2023.03.30

초록

For a locus with two alleles (IA and IB), the frequencies of the alleles are represented by $$p=f(I^A)={\frac{2N_{AA}+N_{AB}}{2N}},\;q=f(I^B)={\frac{2N_{BB}+N_{AB}}{2N}}$$ where NAA, NAB and NBB are the numbers of IAIA, IAIB and IBIB respectively and N is the total number of populations. The frequencies of the genotypes expected are calculated by using p2, 2pq and q2. Choi defined the density and operator for the value of the frequency of one gene and found the adapted partial differential equation as a follow-up for the frequency of alleles and applied this adapted partial differential equation to several diploid model [1]. In this paper, we find adapted equations for the model for selection against recessive homozygotes and in case that the alley frequency changes after one generation of selection when there is no dominance. Also we consider the triploid model with three alleles IA, IB and i and determine whether six genotypes observed are in Hardy-Weinburg for equilibrium.

키워드

과제정보

This research was supported by Incheon National University Research Grant, 2022-2023.

참고문헌

  1. W. Choi, On the adapted equations for several dyploid model in population genetics, Korean J. Math. 30 (1) (2022), 62-72. 
  2. W. Choi, On the genotype frequencies and generating function for frequencies in a dyploid model, Korean J. Math. 29 (1) (2021), 75-80. 
  3. M. Kimura, A Stochastic model of Compensatory Neutral Evolution , Proceedings of a Workshop held in Nagoya, July 8-12, Stochastic Methods in Biology (1985). 
  4. R. Lewis, Human Genetics : Concepts and Applications, McGraw-Hill Education (2016). 
  5. B. A. Pierce, Genetics Essentials : Concepts and Connections, W.H.Freeman and Company (2014), 216-240.