Journal of Korean Medicine Rehabilitation (한방재활의학과학회지)

The society of Korean Medicine Rehabilitation (한방재활의학과학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of Neuromuscular Electrical Stimulation on Muscle Wasting with Cancer Patient: Study Protocol for a Systematic Review

신경근전기자극치료가 암환자의 근육 손실에 미치는 영향: 체계적 문헌고찰을 위한 프로토콜

  • Eun Soo Park (Clinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University) ;
  • Jong Hee Kim (Clinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University) ;
  • Soo Dam Kim (Clinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University) ;
  • Dong Hyun Kim (National Clinical Research Center of Korean Medicine, Korean Medicine Hospital, Pusan University) ;
  • Min Seok Oh (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Eun Jung Lee (Department of Korean Medicine Rehabilitation, College of Korean Medicine, Daejeon University) ;
  • Hwa Seung Yoo (Clinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University)
  • 박은수 (대전대학교 대전한방병원 임상시험센터) ;
  • 김종희 (대전대학교 대전한방병원 임상시험센터) ;
  • 김수담 (대전대학교 대전한방병원 임상시험센터) ;
  • 김동현 (부산대학교 한방병원 한의약 임상연구센터) ;
  • 오민석 (대전대학교 한의과대학 한방재활의학교실) ;
  • 이은정 (대전대학교 한의과대학 한방재활의학교실) ;
  • 유화승 (대전대학교 대전한방병원 임상시험센터)
  • Received : 2023.03.15
  • Accepted : 2023.04.09
  • Published : 2023.04.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives The purpose of this study is to analyze randomized controlled trials about neuromuscular electrical stimulation for muscle wasting with cancer patient and evaluate it's motor functionality effect. Methods Studies will be searched from 7 online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Participants will be cancer patients with muscle loss, regardless of cause, gender, race or age, interventions will be neuromuscular electrical stimulation. Other treatments than interventions will be the control group and the main outcome will be reviewed by motor functionality effect. Results Randomized controlled trials about neuromuscular electrical stimulation for muscle wasting should be included in the study. Primary outcomes include motor functionality effect. Secondary outcomes evaluate adverse event. The data uses Review Manager Software 5.4. Conclusions The conclusion of this study will provide a basis for determining whether neuromuscular electrical stimulation treatment for muscle wasting with cancer patient treatment is an effective and safe treatment method in clinical practice.

Keywords

Acknowledgement

This study was supported by the 2022 Startup Commercialization Support Project funded by the Ministry of Small and Medium-sized Enterprises and Startups (Project No. 20052267).

References

  1. National Cancer Information Center. National Cancer Registration Project statistics report (2020 cancer registration statistics). National Cancer Information Center. 2020. 
  2. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2021;71(3):209-49.  https://doi.org/10.3322/caac.21660
  3. Park SB, Yoon JH, Kim EH, Lee JY, Yoon SW. A review of studies using syndrome differentiation questionnaire in cancer patients. Journal of Korean Traditional Oncology. 2021;26(1):1-15.  https://doi.org/10.15432/JKTO.2021.26.1.001
  4. Choi YJ, Lee JS, Cho SH. Use of Korean medicine among cancer patients. The Journal of Korean Medicine. 2012;33(3):46-53.  https://doi.org/10.3341/jkos.2012.53.4.559
  5. Barreto R, Mandili G, Witzmann FA, Novelli F, Zimmers TA, Bonetto A. Cancer and chemotherapy contribute to muscle loss by activating common signaling pathways. Frontiers in Physiology. 2016;7:472. 
  6. Barreto R, Waning DL, Gao H, Liu Y, Zimmers TA, Bonetto A. Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. Oncotarget. 2016;7(28):43442-60.  https://doi.org/10.18632/oncotarget.9779
  7. Daly LE, Ni Bhuachalla EB, Power DG, Cushen SJ, James K, Ryan AM. Loss of skeletal muscle during systemic chemotherapy is prognostic of poor survival in patients with foregut cancer. J Cachexia Sarcopenia Muscle. 2018;9(2):315-25.  https://doi.org/10.1002/jcsm.12267
  8. Stene GB, Helbostad JL, Amundsen T, Sorhaug S, Hjelde H, Kaasa S, Gronberg BH. Changes in skeletal muscle mass during palliative chemotherapy in patients with advanced lung cancer. Acta Oncologica. 2015;54(3):340-8.  https://doi.org/10.3109/0284186X.2014.953259
  9. Windholz T, Swanson T, Vanderbyl BL, Jagoe RT. The feasibility and acceptability of neuromuscular electrical stimulation to improve exercise performance in patients with advanced cancer: a pilot study BMC Palliative Care. 2014;13:23. 
  10. Bax L, Staes F, Verhagen A. Does neuromuscular electrical stimulation strengthen the quadriceps femoris? A systematic review of randomised controlled trials. Sports Medicine. 2005;35(3):191-212.  https://doi.org/10.2165/00007256-200535030-00002
  11. Maillefert JF, Eicher JC, Walker P, Dulieu V, Rouhier-Marcer I, Branly F, Cohen M, Brunotte F, Wolf JE, Casillas JM, Didier JP. Effects of low-frequency electrical stimulation of quadriceps and calf muscles in patients with chronic heart failure. Journal of Cardiopulmonary Rehabilitation. 1998;18(4):277-82.  https://doi.org/10.1097/00008483-199807000-00004
  12. Deley G, Eicher JC, Verges B, Wolf JE, Casillas JM. Do low-frequency electrical myostimulation and aerobic training similarly improve performance in chronic heart failure patients with different exercise capacities? Journal of Rehabilitation Medicine. 2008;40(3):219-24.  https://doi.org/10.2340/16501977-0153
  13. Crevenna R, Marosi C, Schmidinger M, Fialka-Moser V. Neuromuscular electrical stimulation for a patient with metastatic lung cancer-a case report. Support Care Cancer. 2006;14(9):970-73.  https://doi.org/10.1007/s00520-006-0033-x
  14. Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA; Cochrane Bias Methods Group, Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. 
  15. Yazaki Y. Asakura internal medicine. 11th ed. Wooripub. 2020:28. 
  16. Freter CE, Longo DL. 125 late consequences of cancer and its treatment. In: Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J, eds. Harrison's principles of internal medicine. 19th ed. McGraw-Hill Professional Pub. 2018:620-5. 
  17. Yates JS, Mustian KM, Morrow GR, Gillies LJ, Padmanaban D, Atkins JN, Issell B, Kirshner JJ, Colman LK. Prevalence of complementary and alternative medicine use in cancer patients during treatment. Support Care Cancer. 2005;13(10):806-11.  https://doi.org/10.1007/s00520-004-0770-7
  18. Anjanappa M, Corden M, Green A, Roberts D, Hoskin P, McWilliam A, Choudhury A. Sarcopenia in cancer: risking more than muscle loss. Technical Innovations & Patient Support in Radiation Oncology. 2020;16:50-7.  https://doi.org/10.1016/j.tipsro.2020.10.001
  19. Fong DY, Ho JW, Hui BP, Lee AH, Macfarlane DJ, Leung SS, Cerin E, Chan WY, Leung IP, Lam SH, Taylor AJ, Cheng KK. Physical activity for cancer survivors: meta-analysis of randomised controlled trials. BMJ. 2012;344:e70. 
  20. Larsson L, Degens H, Li M, Salviati L, Lee YI, Thompson W, Kirkland JL, Sandri M. Sarcopenia: aging-related loss of muscle mass and function. Physiological Reviews. 2019;99(1):427-511. https://doi.org/10.1152/physrev.00061.2017