Mycobiology

  • 제51권3호
  • /
  • Pages.148-156
  • /
  • 2023
  • /
  • 1229-8093(pISSN)
  • /
  • 2092-9323(eISSN)
한국균학회 (The Korean Society of Mycology)
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Metabolite Chemical Composition of the Bletilla striata (Thunb.) Reichb. f. Endophyte Penicillium oxalicum

  • Ran Liu (School of Pharmacy, Chengdu University of Traditional Chinese Medicine) ;
  • Xuehua Han (School of Pharmacy, Chengdu University of Traditional Chinese Medicine) ;
  • Jing Gao (School of Pharmacy, Chengdu University of Traditional Chinese Medicine) ;
  • Min Luo (School of Pharmacy, Chengdu University of Traditional Chinese Medicine) ;
  • Dale Guo (School of Pharmacy, Chengdu University of Traditional Chinese Medicine) ;
  • Guangzhi Wang (School of Pharmacy, Chengdu University of Traditional Chinese Medicine)
  • 투고 : 2022.12.20
  • 심사 : 2023.05.08
  • 발행 : 2023.06.30
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초록

Penicillium oxalicum strain can be isolated from the Bletilla striata (Thunb.) Reichb. f. tubers. Its solid-state fermentation products are concentrated by percolation extraction. Separation and purification have been conducted to the ethyl acetate extracts by preparative HPLC. Based on the use of spectrometry, we have determined 17 known compounds, 12,13-dihydroxy-fumitremorgin C (1), pseurotin A (2), tyrosol (3), cyclo-(L-Pro-L-Val) (4), cis-4-hydroxy-8-O-methylmellein (5), uracil (6), cyclo-(L-Pro-L-Ala) (7), 1,2,3,4-tetrahydro-4-hydroxy-4-quinolin carboxylic acid (8), cyclo-(Gly-L-Pro) (9), 2'-deoxyuridine (10), 1-(b-D-ribofuranosyl)thymine (11), cyclo-(L-Val-Gly) (12), 2'-deoxythymidine (13), cyclo-(Gly-D-Phe) (14), cyclo-L-(4-hydroxyprolinyl)-D-leucine (15), cyclo-(L)-4-hydroxy-Pro-(L)-Phe (16), uridine (17). Here, we report compounds 1-3, 5, 7-8, 11-12, 14-17 are first found and isolated from this endophyte.

키워드

과제정보

The authors are grateful for the support from the Basic Research Project of Science and Technology, Department of Sichuan Province (grant no. 2021YJ0110).

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