Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis

  • Jihun Oh (Department of Acupuncture and Moxibustion, Mokhuri Neck and Back Hospital) ;
  • Jaewoo Yang (Department of Acupuncture and Moxibustion, Mokhuri Neck and Back Hospital) ;
  • Jungmin Yang (Department of Korean Internal Medicine, Mokhuri Neck and Back Hospital) ;
  • Minsoo Kang (Mokhuri Neck and Back Hospital) ;
  • Sukyoung Kim (Mokhuri Neck and Back Hospital) ;
  • Minjun Lee (Mokhuri Neck and Back Hospital) ;
  • Jinwoong Lim (Department of Acupuncture and Moxibustion, Wonkwang University Gwangju Korean Medicine Hospital)
  • Received : 2023.05.05
  • Accepted : 2023.06.16
  • Published : 2023.08.31
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Abstract

Laryngopharyngeal reflux (LPR) disease is a condition in which the stomach contents return to the larynx and pharynx via the esophagus, causing mucosal injury. While conventional treatments, such as proton pump inhibitors, have limitations, acupuncture has been shown to reduce LPR symptoms. However, its effectiveness has not been systematically assessed. This study aimed to systematically evaluate the effectiveness of acupuncture in treating LPR. We review 10 electronic databases with a consistent search strategy, and 2 independent reviewers screened the articles based on the inclusion and exclusion criteria. This study selected and analyzed 7 randomized controlled trials after the screening to assess primary outcomes, including reflux symptom index and reflux finding score, and secondary outcomes, including upper and lower esophageal sphincter pressure. The results revealed the statistically significant effectiveness of acupuncture in combination with conventional treatment in reducing LPR symptoms compared with conventional treatment alone. The most commonly used acupuncture points were CV22, ST36, and LR3. However, the meta-analysis demonstrated low reliability, as assessed using the GRADE Tool. Further research is needed to improve the evidence and draw clear conclusions regarding the clinical use of acupuncture for treating LPR.

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References

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