DOI QR코드

DOI QR Code

Core decompression for early-stage avascular necrosis of the humeral head: current concepts and techniques

  • Michael D. Scheidt (Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center) ;
  • Saleh Aiyash (Department of General Surgery, Huntington Memorial Hospital) ;
  • Dane Salazar (Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center) ;
  • Nickolas Garbis (Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center)
  • Received : 2022.04.13
  • Accepted : 2022.07.07
  • Published : 2023.06.01

Abstract

Avascular necrosis (AVN) of the humeral head is a rare, yet detrimental complication. Left untreated, humeral head AVN frequently progresses to subchondral fracturing and articular collapse. Cases of late-stage humeral head AVN commonly require invasive procedures including humeral head resurfacing, hemiarthroplasty, and total shoulder arthroplasty (TSA) to improve clinical outcomes. However, in cases of early-stage AVN, core decompression of the humeral head is a viable and efficacious short-term treatment option for patients with pre-collapse AVN of the humeral head to improve clinical outcomes and prevent disease progression. Several techniques have been described, however, a percutaneous, arthroscopic-assisted technique may allow for accurate staging and concomitant treatment of intraarticular pathology during surgery, although further long-term clinical studies are necessary to assess its overall outcomes compared with standard techniques. Biologic adjunctive treatments, including synthetic bone grafting, autologous mesenchymal stem cell/bone marrow grafts, and bone allografts are viable options for reducing the progression of AVN to further collapse in the short term, although long-term follow-up with sufficient study power is lacking in current clinical studies. Further long-term outcome studies are required to determine the longevity of core decompression as a conservative measure for early-stage AVN of the humeral head.

Keywords

References

  1. Cruess RL. Corticosteroid-induced osteonecrosis of the humeral head. Orthop Clin North Am 1985;16:789-96.  https://doi.org/10.1016/S0030-5898(20)30444-2
  2. LaPorte DM, Mont MA, Mohan V, Jones LC, Hungerford DS. Multifocal osteonecrosis. J Rheumatol 1998;25:1968-74. 
  3. Loebenberg MI, Plate AM, Zuckerman JD. Osteonecrosis of the humeral head. Instr Course Lect 1999;48:349-57. 
  4. Usher BW Jr, Friedman RJ. Steroid-induced osteonecrosis of the humeral head. Orthopedics 1995;18:47-51.  https://doi.org/10.3928/0147-7447-19950101-10
  5. L'Insalata JC, Pagnani MJ, Warren RF, Dines DM. Humeral head osteonecrosis: clinical course and radiographic predictors of outcome. J Shoulder Elbow Surg 1996;5:355-61.  https://doi.org/10.1016/S1058-2746(96)80066-8
  6. Cruess RL. Experience with steroid-induced avascular necrosis of the shoulder and etiologic considerations regarding osteonecrosis of the hip. Clin Orthop Relat Res 1978;(130):86-93. 
  7. Levy O, Tsvieli O, Merchant J, et al. Surface replacement arthroplasty for glenohumeral arthropathy in patients aged younger than fifty years: results after a minimum ten-year follow-up. J Shoulder Elbow Surg 2015;24:1049-60.  https://doi.org/10.1016/j.jse.2014.11.035
  8. Raiss P, Kasten P, Baumann F, Moser M, Rickert M, Loew M. Treatment of osteonecrosis of the humeral head with cementless surface replacement arthroplasty. J Bone Joint Surg Am 2009;91:340-9.  https://doi.org/10.2106/JBJS.H.00560
  9. Franceschi F, Franceschetti E, Paciotti M, et al. Surgical management of osteonecrosis of the humeral head: a systematic review. Knee Surg Sports Traumatol Arthrosc 2017;25:3270-8.  https://doi.org/10.1007/s00167-016-4169-z
  10. Kennon JC, Smith JP, Crosby LA. Core decompression and arthroplasty outcomes for atraumatic osteonecrosis of the humeral head. J Shoulder Elbow Surg 2016;25:1442-8.  https://doi.org/10.1016/j.jse.2016.01.022
  11. Harreld KL, Marulanda GA, Ulrich SD, Marker DR, Seyler TM, Mont MA. Small-diameter percutaneous decompression for osteonecrosis of the shoulder. Am J Orthop (Belle Mead NJ) 2009;38:348-54. 
  12. LaPorte DM, Mont MA, Mohan V, Pierre-Jacques H, Jones LC, Hungerford DS. Osteonecrosis of the humeral head treated by core decompression. Clin Orthop Relat Res 1998;(355):254-60. 
  13. Mont MA, Maar DC, Urquhart MW, Lennox D, Hungerford DS. Avascular necrosis of the humeral head treated by core decompression: a retrospective review. J Bone Joint Surg Br 1993;75:785-8.  https://doi.org/10.1302/0301-620X.75B5.8376440
  14. Sahajpal DT, Zuckerman JD. Core decompression for nontraumatic osteonecrosis of the humeral head: a technique article. Bull NYU Hosp Jt Dis 2008;66:118-9. 
  15. Hua KC, Yang XG, Feng JT, et al. The efficacy and safety of core decompression for the treatment of femoral head necrosis: a systematic review and meta-analysis. J Orthop Surg Res 2019;14:306. 
  16. Marker DR, Seyler TM, Ulrich SD, Srivastava S, Mont MA. Do modern techniques improve core decompression outcomes for hip osteonecrosis. Clin Orthop Relat Res 2008;466:1093-103.  https://doi.org/10.1007/s11999-008-0184-9
  17. Mazieres B, Marin F, Chiron P, et al. Influence of the volume of osteonecrosis on the outcome of core decompression of the femoral head. Ann Rheum Dis 1997;56:747-50.  https://doi.org/10.1136/ard.56.12.747
  18. Mont MA, Jones LC, Pacheco I, Hungerford DS. Radiographic predictors of outcome of core decompression for hips with osteonecrosis stage III. Clin Orthop Relat Res 1998;(354):159-68. 
  19. Iorio R, Healy WL, Abramowitz AJ, Pfeifer BA. Clinical outcome and survivorship analysis of core decompression for early osteonecrosis of the femoral head. J Arthroplasty 1998;13:34-41.  https://doi.org/10.1016/S0883-5403(98)90073-0
  20. Yoon TR, Song EK, Rowe SM, Park CH. Failure after core decompression in osteonecrosis of the femoral head. Int Orthop 2001;24:316-8.  https://doi.org/10.1007/s002640000186
  21. Pierce TP, Jauregui JJ, Elmallah RK, Lavernia CJ, Mont MA, Nace J. A current review of core decompression in the treatment of osteonecrosis of the femoral head. Curr Rev Musculo-skelet Med 2015;8:228-32.  https://doi.org/10.1007/s12178-015-9280-0
  22. Patel S, Colaco HB, Elvey ME, Lee MH. Post-traumatic osteonecrosis of the proximal humerus. Injury 2015;46:1878-84.  https://doi.org/10.1016/j.injury.2015.06.026
  23. Hernigou P, Hernigou J, Scarlat M. Shoulder osteonecrosis: pathogenesis, causes, clinical evaluation, imaging, and classification. Orthop Surg 2020;12:1340-9.  https://doi.org/10.1111/os.12788
  24. Solberg BD, Moon CN, Franco DP, Paiement GD. Surgical treatment of three and four-part proximal humeral fractures. J Bone Joint Surg Am 2009;91:1689-97.  https://doi.org/10.2106/JBJS.H.00133
  25. Greiner S, Kaab MJ, Haas NP, Bail HJ. Humeral head necrosis rate at mid-term follow-up after open reduction and angular stable plate fixation for proximal humeral fractures. Injury 2009;40:186-91.  https://doi.org/10.1016/j.injury.2008.05.030
  26. Hertel R, Hempfing A, Stiehler M, Leunig M. Predictors of humeral head ischemia after intracapsular fracture of the proximal humerus. J Shoulder Elbow Surg 2004;13:427-33.  https://doi.org/10.1016/j.jse.2004.01.034
  27. Resch H, Povacz P, Frohlich R, Wambacher M. Percutaneous fixation of three-and four-part fractures of the proximal humerus. J Bone Joint Surg Br 1997;79:295-300.  https://doi.org/10.1302/0301-620X.79B2.0790295
  28. Crosby LA, Finnan RP, Anderson CG, Gozdanovic J, Miller MW. Tetracycline labeling as a measure of humeral head viability after 3- or 4-part proximal humerus fracture. J Shoulder Elbow Surg 2009;18:851-8.  https://doi.org/10.1016/j.jse.2008.12.016
  29. Hattrup SJ, Cofield RH. Osteonecrosis of the humeral head: relationship of disease stage, extent, and cause to natural history. J Shoulder Elbow Surg 1999;8:559-64.  https://doi.org/10.1016/S1058-2746(99)90089-7
  30. Jones JP Jr. Concepts of etiology and early pathogenesis of osteonecrosis. Instr Course Lect 1994;43:499-512. 
  31. Chung SM, Ralston EL. Necrosis of the humeral head associated with sickle cell anemia and its genetic variants. Clin Orthop Relat Res 1971;80:105-17. https://doi.org/10.1097/00003086-197110000-00015
  32. Jacobs B. Epidemiology of traumatic and nontraumatic osteonecrosis. Clin Orthop Relat Res 1978;(130):51-67. 
  33. Hernigou P, Flouzat-Lachaniette CH, Roussignol X, Poignard A. The natural progression of shoulder osteonecrosis related to corticosteroid treatment. Clin Orthop Relat Res 2010;468:1809-16.  https://doi.org/10.1007/s11999-009-1094-1
  34. Milner PF, Kraus AP, Sebes JI, et al. Osteonecrosis of the humeral head in sickle cell disease. Clin Orthop Relat Res 1993;(289):136-43. 
  35. da Silva Junior GB, Daher Ede F, da Rocha FA. Osteoarticular involvement in sickle cell disease. Rev Bras Hematol Hemoter 2012;34:156-64.  https://doi.org/10.5581/1516-8484.20120036
  36. Mont MA, Payman RK, Laporte DM, Petri M, Jones LC, Hungerford DS. Atraumatic osteonecrosis of the humeral head. J Rheumatol 2000;27:1766-73. 
  37. Orlic D , Jovanovic S, Anticevic D, Zecevic J. Frequency of idiopathic aseptic necrosis in medically treated alcoholics. Int Orthop 1990;14:383-6.  https://doi.org/10.1007/BF00182650
  38. Jacobs B. Alcoholism-induced bone necrosis. N Y State J Med 1992;92:334-8. 
  39. Gerster JC, Camus JP, Chave JP, Koeger AC, Rappoport G. Multiple site avascular necrosis in HIV infected patients. J Rheumatol 1991;18:300-2. 
  40. Attarian DE. Multifocal osteonecrosis and human immunodeficiency virus infection. J South Orthop Assoc 2002;11:172-3. 
  41. Verbon A, Prins JM. Shoulder pain in two HIV-seropositive patients: avascular necrosis (AVN) of the bone. Neth J Med 2010;68:322-5. 
  42. Gregg PJ, Walder DN. Caisson disease of bone. Clin Orthop Relat Res 1986;(210):43-54. 
  43. Slichter SJ, Stegall P, Smith K, Huang TW, Harker LA. Dysbaric osteonecrosis: a consequence of intravascular bubble formation, endothelial damage, and platelet thrombosis. J Lab Clin Med 1981;98:568-90. 
  44. Colegate-Stone TJ, Aggarwal S, Karuppaiah K, Tavakkolizadeh A, Sinha J, Reichert IL. The staged management of gleno-humeral joint osteonecrosis in patients with haematological-in-duced disease: a cohort review. Int Orthop 2018;42:1651-9.  https://doi.org/10.1007/s00264-018-3957-0
  45. Ficat RP. Idiopathic bone necrosis of the femoral head: early diagnosis and treatment. J Bone Joint Surg Br 1985;67:3-9.  https://doi.org/10.1302/0301-620X.67B1.3155745
  46. Dines JS, Strauss EJ, Fealy S, Craig EV. Arthroscopic-assisted core decompression of the humeral head. Arthroscopy 2007;23:103e1-4. 
  47. Steffensmeier AM, Kirkham K, Wiemann JM. Core decompression with synthetic grafting as a joint preservation strategy in humeral avascular necrosis due to sickle cell anemia: a case report. J Orthop Case Rep 2016;6:62-4. 
  48. Makihara T, Yoshioka T, Sugaya H, Yamazaki M, Mishima H. Autologous concentrated bone marrow grafting for the treatment of osteonecrosis of the humeral head: a report of five shoulders in four cases. Case Rep Orthop 2017;2017:4898057. 
  49. Galloway MR, Horodyski M, Wright TW. Arthroscopically assisted fibular strut allograft for treatment of osteonecrosis of proximal humerus. J Surg Orthop Adv 2013;22:277-82.  https://doi.org/10.3113/JSOA.2013.0277
  50. Zlotolow DA, Catalano LW 3rd, Barron OA, Glickel SZ. Surgical exposures of the humerus. J Am Acad Orthop Surg 2006;14:754-65.  https://doi.org/10.5435/00124635-200612000-00007
  51. Mont MA, Ragland PS, Etienne G. Core decompression of the femoral head for osteonecrosis using percutaneous multiple small-diameter drilling. Clin Orthop Relat Res 2004;(429):131-8. 
  52. Gerber C, Schneeberger AG, Vinh TS. The arterial vascularization of the humeral head: an anatomical study. J Bone Joint Surg Am 1990;72:1486-94.  https://doi.org/10.2106/00004623-199072100-00009
  53. Chapman C, Mattern C, Levine WN. Arthroscopically assisted core decompression of the proximal humerus for avascular necrosis. Arthroscopy 2004;20:1003-6.  https://doi.org/10.1016/S0749-8063(04)00796-0
  54. Liu ZH, Guo WS, Li ZR, et al. Porous tantalum rods for treating osteonecrosis of the femoral head. Genet Mol Res 2014;13:8342-52.  https://doi.org/10.4238/2014.October.20.10
  55. Nadeau M, Seguin C, Theodoropoulos JS, Harvey EJ. Short term clinical outcome of a porous tantalum implant for the treatment of advanced osteonecrosis of the femoral head. Mcgill J Med 2007;10:4-10.  https://doi.org/10.26443/mjm.v10i1.462
  56. Zhang Y, Li L, Shi ZJ, Wang J, Li ZH. Porous tantalum rod implant is an effective and safe choice for early-stage femoral head necrosis: a meta-analysis of clinical trials. Eur J Orthop Surg Traumatol 2013;23:211-7.  https://doi.org/10.1007/s00590-012-0962-7
  57. Li X, Xu X, Wu W. Comparison of bone marrow mesenchymal stem cells and core decompression in treatment of osteonecrosis of the femoral head: a meta-analysis. Int J Clin Exp Pathol 2014;7:5024-30. 
  58. Civinini R, De Biase P, Carulli C, et al. The use of an injectable calcium sulphate/calcium phosphate bioceramic in the treatment of osteonecrosis of the femoral head. Int Orthop 2012;36:1583-8.  https://doi.org/10.1007/s00264-012-1525-6
  59. Sionek A, Czwojdzinski A, Ko walcze wski J, et al. Hip osteonecroses treated with calcium sulfate-calcium phosphate bone graft substitute have different results according to the cause of osteonecrosis: alcohol abuse or corticosteroid-induced. Int Orthop 2018;42:1491-8.  https://doi.org/10.1007/s00264-018-3892-0
  60. Luo Y, Li D, Xie X, Kang P. Porous, lithium-doped calcium polyphosphate composite scaffolds containing vascular endothelial growth factor (VEGF)-loaded gelatin microspheres for treating glucocorticoid-induced osteonecrosis of the femoral head. Biomed Mater 2019;14:035013. 
  61. Yu PA, Peng KT, Huang TW, Hsu RW, Hsu WH, Lee MS. Injectable synthetic bone graft substitute combined with core decompression in the treatment of advanced osteonecrosis of the femoral head: a 5-year follow-up. Biomed J 2015;38:257-61.  https://doi.org/10.4103/2319-4170.138307
  62. Chang CH, Liao TC, Hsu YM, Fang HW, Chen CC, Lin FH. A poly(propylene fumarate)--calcium phosphate based angiogenic injectable bone cement for femoral head osteonecrosis. Biomaterials 2010;31:4048-55.  https://doi.org/10.1016/j.biomaterials.2010.01.124
  63. Zhao P, Hao J. Analysis of the long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on nontraumatic osteonecrosis of the femoral head. Med Sci (Paris) 2018;34:43-6.  https://doi.org/10.1051/medsci/201834f108
  64. Jiang HJ, Huang XJ, Tan YC, Liu DZ, Wang L. Core decompression and implantation of calcium phosphate cement/Danshen drug delivery system for treating ischemic necrosis of femoral head at Stages I, II and III of antigen reactive cell opsonization. Chin J Traumatol 2009;12:285-90. 
  65. Evaniew N, Tan V, Parasu N, et al. Use of a calcium sulfate-calcium phosphate synthetic bone graft composite in the surgical management of primary bone tumors. Orthopedics 2013;36:e216-22.  https://doi.org/10.3928/01477447-20130122-25
  66. Yashavantha Kumar C, Nalini KB, Menon J, Patro DK, Banerji BH. Calcium sulfate as bone graft substitute in the treatment of osseous bone defects, a prospective study. J Clin Diagn Res 2013;7:2926-8.  https://doi.org/10.7860/JCDR/2013/6404.3791
  67. Yoshioka T, Mishima H, Akaogi H, Sakai S, Li M, Ochiai N. Concentrated autologous bone marrow aspirate transplantation treatment for corticosteroid-induced osteonecrosis of the femoral head in systemic lupus erythematosus. Int Orthop 2011;35:823-9.  https://doi.org/10.1007/s00264-010-1048-y
  68. Hernigou J, Bastard C, Dubory A, Zilber S, Flouzat Lachaniette CH, Rouard H, et al. Cell therapy for posttraumatic shoulder osteonecrosis. Morphologie 2021;105:162-9. https://doi.org/10.1016/j.morpho.2020.11.006