The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Trends in Animal Experiments for Herbal Medicine Treatment of Atopic Dermatitis: During the 10 year's results

한약의 아토피피부염에 대한 국내외 동물실험 연구 동향: 최근 10년을 중심으로

  • Jeong Aram (Department of Pediatrics, College of Korean Medicine, Gachon University)
  • 정아람 (가천대학교 한의과대학 소아과학교실)
  • Received : 2023.07.14
  • Accepted : 2023.08.23
  • Published : 2023.08.31
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Abstract

Objectives The aim of this study was to analyze the research trends in herbal medicine as a treatment for atopic dermatitis (AD) in an animal model. Methods We conducted a search targeting papers published from 2013 onwards in Korean and English databases. The search terms were focused on "AD", "dermatitis", and "Korean medicine". Only animal experimental studies involving the oral administration of single or complex prescriptions of Korean medicine were included, whereas in vitro studies, local administration studies, and studies of specific components of Korean medicine were excluded. We searched the PubMed and Embase databases for English databases and the Science on Research Information Sharing Service (RISS) and Korean Studies Information Service System (KISS) databases for Korean studies. Results Among the herbal medicine intervention groups, the most commonly used single herbs were baekseonpi, danggui, and douchi, whereas a mixture of hwangryun and gamcho was used in three studies, making it the most frequently used combination. There were significant improvements in indicators related to the symptoms of AD and various pro-inflammatory markers. Conclusions These results indicate the efficacy of herbal medicines in the treatment of AD in animal models. However, this study had several limitations. Therefore, future systematic reviews that address these limitations and provide more comprehensive analyses are required.

Keywords

Acknowledgement

이 성과는 정부 (과학기술정보통신부)의 재원으로 한국연구재단의 지원을 받아 수행된 연구임 (No. 2020R1F1A1061970).

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