DOI QR코드

DOI QR Code

Acupuncture Treatment for Restless Legs Syndrome: A Review of Randomized Controlled Trials

  • Go Eun Chae (Department of Acupuncture and Moxibustion Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Hyun Woo Kim (Department of Acupuncture and Moxibustion Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Hye Jeong Jo (Department of Acupuncture and Moxibustion Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Ahra Koh (Department of Rehabilitation Medicine of Korean Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Young Jin Lee (Department of Rehabilitation Medicine of Korean Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Ji Eun Choi (Department of Rehabilitation Medicine of Korean Medicine, Ulsan Jaseng Korean Medicine Hospital) ;
  • Woo Young Kim (Department of Acupuncture and Moxibustion Medicine, Ulsan Jaseng Korean Medicine Hospital)
  • Received : 2023.09.21
  • Accepted : 2023.10.23
  • Published : 2023.11.30

Abstract

To determine the effectiveness of acupuncture in treating restless legs syndrome (RLS), we conducted a literature review of randomized controlled trials (RCTs) that utilized acupuncture as an intervention for patients diagnosed with RLS. Relevant clinical studies (n = 158) from seven databases (the Cochrane Library, PubMed, Embase, CNKI, KISS, RISS, and OASIS) were included based on the inclusion and exclusion criteria and analyzed. Moreover, 6 RCTs were selected for review. In all six studies, it was indicated people who underwent acupuncture treatment showed significant improvements in their overall health. An increase in the treatment efficacy rate, sleep quality, and quality of life indicators after the acupuncture treatment was confirmed. The severity of pain as assessed using the visual analog scale (VAS) scores and International RLS Study Group Rating Scale (IRLSRS) scores and the severity of RLS symptoms were significantly reduced. Any significant side effects were not reported. Acupuncture is suggested as an effective and safe treatment method for RLS. However, further large-scale RCT studies are needed to confirm our findings.

Keywords

References

  1. Yang JY, Kim SW, Lee YJ, Cho KH, Moon SK, Jung WS, et al. A case of restless legs syndrome patient with numbness in both soles using Gyejibokryeong-hwan. J Int Korean Med 2019;40:270-278. doi: 10.22246/jikm.2019.40.2.270 
  2. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-119. doi: 10.1016/s1389-9457(03)00010-8 
  3. Cho YW, Shin WC, Yun CH, Hong SB, Kim JH, Allen RP, et al. Epidemiology of restless legs syndrome in Korean adults. Sleep 2008;31:219-223. doi: 10.1093/sleep/31.2.219 
  4. Ahn SM, Hong JS, Choo WJ, Lee SJ, Shin SJ, Choi YS. A case report on post spinal surgery syndrome in restless leg syndrome. J Int Korean Med 2016;37:717-725. doi: 10.22246/jikm.2016.37.5.717 
  5. Yim TB, Jeon GR, Lee HJ, Kim SY, Cho SY, Park SU, et al. A case report of patient with restless legs syndrome improved by Gami Ssanghwa-tang. J Soc Stroke Korean Med 2021;22:1-10. 
  6. Rui Z, Kesong L, Lizing Z. Cumulative meta-analysis on efficacy of acupuncture therapy for restless legs syndrome. Tianjin J Tradit Chin Med 2019;36:579-583. 
  7. Huang C, Tang JF, Sun W, Wang LZ, Jin YS. Effectiveness of acupuncture in the management of restless leg syndrome: a systematic review and meta-analysis. Ann Palliat Med 2021;10:10495-10505. doi: 10.21037/apm-21-2309 
  8. Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page M, et al. Cochrane handbook for systematic reviews of interventions version 6.3. Cochrane [Internet]. 2022 Feb [cited 2023 Aug 30]. Available from: https://training.cochrane.org/handbook/archive/v6.3 
  9. Fukutome T, Murashima K. Effects of acupuncture on sensory symptoms and motor signs in patients with restless legs syndrome: a crossover randomized controlled trial. Medicine (Baltimore) 2022;101:e32317. doi: 10.1097/MD.0000000000032317 
  10. Li LX, Wang GM, Wen FY, Song YQ. Therapeutic observation of acupuncture on restless legs syndrome. Chin Arch Tradit Chin Med 2007;3:621-622. doi: 10.13193/j.archtcm.2007.03.206.lilx.101 
  11. Wu YH, Sun CL, Wu D, Huang YY, Chi CM. [Observation on therapeutic effect of acupuncture on restless legs syndrome]. Zhongguo Zhen Jiu 2008;28:27-29. Chinese. 
  12. Tang SX, Tang P. Sleep quality effect of Restless Legs syndrome patients treated by acupuncture combined with medicine. Liaoning J Tradit Chin Med 2009;36:114-115. doi: 10.13192/j.ljtcm.2009.01.118.tangshx.078 
  13. Raissi GR, Forogh B, Ahadi T, Ghahramanpoori S, Ghaboussi P, Sajadi S. Evaluation of acupuncture in the treatment of restless legs syndrome: a randomized controlled trial. J Acupunct Meridian Stud 2017;10:346-350. doi: 10.1016/j.jams.2017.08.004 Erratum in: J Acupunct Meridian Stud 2018;11:380. 
  14. Fan S, Yu Q, Zhang Y. Effect analysis of pregabalin combined with acupuncture on MHD restless leg syndrome. Drug Eval 2022;21:1328-1331. 
  15. Sleep Science Group; Branch of Neurology; Chinese Medical Doctor Association; Chinese Society of Sleep Disorders; Sleep Disorders Professional Committee; Chinese Sleep Research Society. Diagnostic and therapeutic guidelines for restless legs syndrome in China (2021 edition). J Natl Med J Chin 2021;101:908-925. doi: 10.3760/cma.j.cn112137-20200820-02431 
  16. Kang SG. Updates on the diagnosis and treatment of restless legs syndrome. J Korean Neuropsychiatr Assoc 2020;59:13-19. doi: 10.4306/jknpa.2020.59.1.13 
  17. Min YS. Diagnosis and treatment of restless legs syndrome. Brain Neurorehabil 2016;9:25-30. doi: 10.12786/bn.2016.9.1.25 
  18. Karatas M. Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment. Neurologist 2007;13:294-301. doi: 10.1097/NRL.0b013e3181422589 
  19. Lee KW. Pyeonju interpretation of yellow emperor's inner canon. Yeogang. 1994:343. 
  20. Lee KW. Pyeonju interpretation of yellow emperor's inner canon. Yeogang. 1994:325. 
  21. Sh anshan W, Jianguo Z. [Current status of traditional Chinese medicine treatment of restless legs syndrome]. Chin Folk Med 2007;23:63-64. Chinese. 
  22. Doo KH, Lee JH, Cho SY, Jung WS, Moon SK, Park JM, et al. A prospective open-label study of combined treatment for idiopathic Parkinson's disease using acupuncture and bee venom acupuncture as an adjunctive treatment. J Altern Complement Med 2015;21:598-603. doi: 10.1089/acm.2015.0078 
  23. Yoo SW, Park SJ. A case report of restless leg syndrome in ischemic stroke patient by acupuncture. Korean J Joongpoong 2012;13:111-117.