Journal of Marine Bioscience and Biotechnology (한국해양바이오학회지)

The Korean Society for Marine Biotechnology (한국해양바이오학회)
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The potential of marine polysaccharide in biomedical applications for applying glycomics technologies

당질체학 기술 적용을 위한 해양 다당체의 의공학적 응용 가능성

  • Tae-Hee Kim (Research Center for Marine-Integrated Bionics Technology, Pukyong National University) ;
  • Se-Chang Kim (Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University) ;
  • Won-Kyo Jung (Research Center for Marine-Integrated Bionics Technology, Pukyong National University)
  • 김태희 (국립부경대학교 공학연구원 해양바이오닉스융합기술센터) ;
  • 김세창 (국립부경대학교 교육부 지정 이공분야 대학중점연구소 해양바이오닉스융합기술센터) ;
  • 정원교 (국립부경대학교 공학연구원 해양바이오닉스융합기술센터)
  • Received : 2024.10.21
  • Accepted : 2024.11.12
  • Published : 2024.12.31
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Abstract

Marine polysaccharides, such as alginate, chitosan, and fucoidan, have excellent biocompatibility and biodegradability as well as low inflammatory response, making them promising candidates for application in biomedical engineering. Biomedical engineering, which aims to develop physiological and biological substitutes to treat tissue loss due to disease, congenital abnormalities, or trauma, has garnered considerable attention. Moreover, the field highly emphasizes on designing biomimetic materials. Although understanding the biological effects and mechanisms of these materials through omics technologies is essential for advancing personalized or disease-targeted biomedical technologies, relatively few studies have explored the biological interactions and mechanisms of marine polysaccharide-based composites. This study provides a thorough overview of marine polysaccharides as biomaterials and examines recent omics-based research trends within biomedical engineering. Although marine polysaccharides have various physiological functions, including potential uses as functional ingredients, nutraceuticals, and cosmetic agents, this review focuses specifically on their effects relevant to biomedical applications.

Keywords

Acknowledgement

This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2021R1A6A1A03039211). This research was also supported by Development of technology for biomaterialization of marine fisheries by-products of Korea institute of Marine Science & Technology Promotion (KIMST) funded by the Ministry of Oceans and Fisheries (KIMST-20220128).

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