Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
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Malignant Transformation from Oral Epithelial Dysplasia: Two Case Reports on the Ventral Tongue

  • Yeonseo Kim (Department of Oral Medicine, Seoul National University Dental Hospital) ;
  • Hee-Kyung Park (Department of Oral Medicine, Seoul National University Dental Hospital)
  • Received : 2024.11.22
  • Accepted : 2024.12.13
  • Published : 2024.12.30
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Abstract

Tongue cancer is one of the most prevalent malignancies in oral and maxillofacial area. Early diagnosis is crucial for improved clinical outcome. Regarding malignant transformation, it is important to understand the concept of oral potentially malignant disorders and oral epithelial dysplasia (OED). We present two cases of oral squamous cell carcinoma (OSCC) developing from OED on ventral tongue. Both of our cases progressed from mild OED to moderate OED, and then severe OED, eventually resulting in OSCC. Our cases underscore that clinicians must look into pathological description of epithelial dysplasia, not only clinical diagnosis of the lesion. Clinical features such as indurated nodules, a mixed white and red appearance, and thick verrucous plaques were closely monitored, enabling the prompt detection of OSCC through biopsy of the relevant site.

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References

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