Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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A Systematic Review of Traditional Herbal Medicine Treatments for Metabolic Syndrome in Patients Receiving Antipsychotic Drugs

항정신병약물 복용 환자의 대사증후군에 대한 한약치료의 체계적 문헌고찰

  • Sun-Woo Lim (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • O-Reun Park (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • So-Hyeon Park (Department of Neuropsychiatry, School of Korean Medicine, Pusan National University) ;
  • Sung-Youl Choi (Department of Neuropsychiatry, College of Korean Medicine, Gachon University) ;
  • Bo-Kyung Kim (Department of Neuropsychiatry, School of Korean Medicine, Pusan National University) ;
  • Jung-Hwa Lim (Department of Neuropsychiatry, School of Korean Medicine, Pusan National University)
  • 임선우 (부산대학교 한의학전문대학원 한의학과) ;
  • 박오른 (부산대학교 한의학전문대학원 한의학과) ;
  • 박소현 (부산대학교 한의학전문대학원 한방신경정신과) ;
  • 최성열 (가천대학교 한의과대학 한방신경정신과) ;
  • 김보경 (부산대학교 한의학전문대학원 한방신경정신과) ;
  • 임정화 (부산대학교 한의학전문대학원 한방신경정신과)
  • Received : 2024.02.25
  • Accepted : 2024.03.25
  • Published : 2024.03.30
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Abstract

Objectives: This study aimed to systematically review the effectiveness and safety of traditional herbal medicine treatments for metabolic syndrome (MS) in patients receiving antipsychotic drugs (APs). Methods: We searched 11 domestic and foreign databases for randomized controlled trials (RCTs) using traditional herbal medicines for MS in patients receiving APs. Results: Twenty RCTs conducted in China were included in the analysis. The most common disease among the participants was schizophrenia. Most studies used the 2004 Chinese Diabetes Society (CDS) standards as the diagnostic criteria for MS. The most used prescription was Yukultang (Liuyu-tang). The most used herbal material was Pinelliae Rhizoma, followed by Poria, Citri Reticulatae Pericarpium, and Glycyrrhizae Radix et Rhizoma. Traditional herbal medicines were mostly reported to improve the symptoms of MS. Conclusions: Traditional herbal medicines may be effective in improving the symptoms of MS in patients receiving APs. However, the quality of the included studies was low, and the studies were heterogeneous. Methodologically rigorous clinical studies on traditional herbal medicine treatments for MS in patients receiving APs are needed.

Keywords

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