Pediatric Infection and Vaccine

  • 제31권1호
  • /
  • Pages.64-74
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  • 2024
  • /
  • 2384-1079(pISSN)
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  • 2384-1087(eISSN)
대한소아감염학회 (The Korean Society of Pediatric Infectious Diseases)
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Hospital-Acquired Measles: A Systematic Review Using the Outbreak Reports and Intervention Studies of Nosocomial Infection (ORION) Statement

  • Erdenetuya Bolormaa (Department of Preventive Medicine, Korea University College of Medicine) ;
  • Cho Ryok Kang (College of Nursing, Seoul National University) ;
  • Han Ho Kim (Department of Pediatrics, Korea University Anam Hospital) ;
  • Young June Choe (Department of Pediatrics, Korea University Anam Hospital)
  • 투고 : 2022.12.18
  • 심사 : 2024.01.11
  • 발행 : 2024.04.25
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초록

최근 의료기관 관련 홍역 유행 사례가 보고되고 있지만, 유행 역학조사 보고서가 표준화되어 있지 않아 질병부담의 크기를 이해하는 데 어려움이 있다. 본 연구에서는 의료기관 관련 감염을 측정하기 위해 개발된 Outbreak Reports and Intervention Studies of Nosocomial Infection (ORION) 조사도구를 사용하여 병원 내에서의 홍역 발생의 크기를 측정하고자 하였다. 본 연구에서는 PubMed, Web of Science, Embase, Scopus 및 Cochrane에서 "measles," "nosocomial," "hospital," 및 "healthcare" 등의 주제어를 사용하여 검색을 수행하였다. 총 24건의 의료기관 관련 홍역 유행 역학조사 연구를 ORION 도구를 활용하여 검토했다. 연구 결과 전 세계적으로 의료기관 내에서의 홍역 전파는 발병률, 사망률 및 경제적으로 중대한 부담을 주고 있는 것을 확인하였다. 의료기관 관련 홍역을 예방하기 위해 의사 및 간호사 등 의료 종사자들의 예방접종 지침이 준수되어야 할 것이며, 특히 표준화된 유행 역학조사 보고서의 활용이 필요하다.

Purpose: Despite the recent increased number of nosocomial measles, the outbreak investigation reports are not usually standardized, thus posing unclear understanding of magnitude of its public health burden. We used the Outbreak Reports and Intervention Studies of Nosocomial Infection (ORION) statement, to compare nosocomial outbreaks and synthesize evidence to prevent hospital transmission of measles. Methods: A PubMed, Web of Science, Embase, Scopus, and Cochrane search in English, using the medical subject headings "measles," "nosocomial," "hospital," and "healthcare," was performed. We evaluated the quality of outbreak reports of nosocomial measles infection worldwide using the ORION statement findings and recommendations. Results: We reviewed 24 studies in accordance to the ORION statement. Measles transmission in healthcare settings is a significant burden on the morbidity, mortality, and economy of measles. The healthcare workers' booster vaccination guidelines should be monitored and enhanced during the post-elimination period of measles. The outcomes of infections must be explicit for outbreak reports. Conclusions: This study identified the epidemiological and clinical characteristics of nosocomial measles infections and provided strong evidence for infection control policies in hospitals.

키워드

과제정보

This study was supported by the Korean Society of Pediatric Infectious Diseases Academic Award, Fall of 2021.

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