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Safety and Effectiveness of Liposuction Modalities in Managing Lipedema: Systematic Review and Meta-analysis

  • Hatan Mortada (Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University) ;
  • Sultan Alaqil (College of Medicine, King Saud University) ;
  • Imtinan Al Jabbar (College of Medicine, King Khalid University) ;
  • Fatimah Alhubail (College of Medicine, King Faisal University) ;
  • Nicolas Pereira (Specialized Center in Lymphedema and Lipedema, Clinica Nea, Hospital del Trabajador) ;
  • Joon Pio Hong (Department of Plastic and Reconstructive Surgery, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Feras Alshomer (Division of Plastic Surgery, Department of Surgery, King Saud Bin Abdulaziz University for Health and Sciences)
  • 투고 : 2023.09.29
  • 심사 : 2024.05.19
  • 발행 : 2024.09.15

초록

Background Lipedema is a chronic, incurable disorder characterized by painful fat accumulation in the extremities. While the application of liposuction in lipedema management has become increasingly popular, the safety and effectiveness of this approach remain contentious. Our systematic review and meta-analysis aimed to assess various liposuction modalities in lipedema management to verify their safety and efficacy. Methods In-line with the Preferred Reporting Items for Systematic Reviews and Metaanalyses guidelines, we performed a comprehensive literature review from inception untilMarch 2023 using the following electronic databases: CENTRAL,MEDLINE, Google Scholar, and EMBASE. Results From the 562 initially identified articles, 20 met our inclusion/exclusion criteria for evaluation. Our review encompassed 14 prospective cohort studies, 3 retrospective studies, 2 case series, and 1 cross-sectional study. Ameta-analysis of nine articles revealed a notable improvement in the quality of life, pain, pressure sensitivity, bruising, cosmetic impairment, heaviness, walking difficulty, and itching among lipedema patients who underwent liposuction. Although complications such as inflammation, thrombosis, seroma, hematoma, and lymphedema-related skin changes were reported, severe complications were rare. Crucially, no instances of shock, recurrence, or mortality were reported.

키워드

과제정보

We would like to express our deepest gratitude to all the authors and researchers whose significant contributions in the form of previously published papers and studies have made this work possible. The breadth and depth of the insights presented in their work have been instrumental in shaping our research. Their meticulous efforts and pioneering work in this field have provided a solid foundation upon which our study stands. Their contributions to the body of knowledge surrounding this topic are not only appreciated but crucial for the advancement of this field of study. It is our honor to build upon their work and continue the dialogue that they have so capably initiated.

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