Animal Bioscience

  • 제37권9호
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  • Pages.1535-1547
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  • 2024
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  • 2765-0189(pISSN)
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  • 2765-0235(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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Genome-wide association research on the reproductive traits of Qianhua Mutton Merino sheep

  • Jiarong Li (College of Animal Science and Technology, Jilin Agricultural University) ;
  • Limin Sun (Institute of Animal Husbandry and Veterinary, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China)) ;
  • Jiazhi Sun (Anhua Agricultural Insurance Co., Ltd. Changchun Central Branch) ;
  • Huaizhi Jiang (College of Animal Science and Technology, Jilin Agricultural University)
  • 투고 : 2023.09.14
  • 심사 : 2024.02.01
  • 발행 : 2024.09.01
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초록

Objective: Qianhua Mutton Merino sheep is a new breed of meat wool sheep cultivated independently in China. In 2018, it was approved by the state and brought into the national list of livestock and poultry genetic resources. Qianhua Mutton Merino sheep have the common characteristics of typical meat livestock varieties with rapid growth and development in the early stage and high meat production performance. The objective of this research is to investigate the Genome-wide association of the reproductive traits of Qianhua Mutton Merino sheep. Methods: Qianhua Mutton Merino sheep from the breeding core group were selected as the research object, genome-wide association analysis was conducted on genes associated with the reproductive traits (singleton or twins, birth weight, age [in days] for sexual maturity, weaning weight, and daily gain from birth to weaning) of Qianhua mutton merino. Results: Our study findings showed that 151 loci of single-nucleotide polymorphisms (SNPs) were detected, among which 3 SNPs related to birth weight and weaning weight occupied a significant portion of the wide genome. The candidate genes preliminarily obtained were SYNE1, SLC12A4, BMP2K, CAMK2D, IMMP2L, DMD, and BCL2. Conclusion: We found 151 SNP loci for five traits related to reproduction (including singleton or twins, birth weight, age [in days] at sexual maturity, weaning weight, and daily weight gain from birth to weaning). The functions of these candidate genes were mainly enriched in nucleotide metabolism, metal ion binding, oxytocin signaling pathway, and neurotrophin signaling pathway.

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과제정보

This work was supported by National Key Research and Development Project of China (2021YFF1000702).

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