Journal of Marine Bioscience and Biotechnology (한국해양바이오학회지)

The Korean Society for Marine Biotechnology (한국해양바이오학회)
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Evaluation of antioxidant and skin anti-aging effects of Polysiphonia morrowii extract

큰수염붉은실(Polysiphonia morrowii) 추출물의 항산화 효과 및 피부 노화 억제 효능 평가

  • Cheol-Young Yoo (Deapartment of Seafood Science and Technology/Institute of Marine Industry, Gyeongsang National University) ;
  • So Ri Jang (Dongwon F&B Changwon Plant Q.A Team) ;
  • Seok-Chun Ko (National Marine Biodiversity Institute of Korea) ;
  • Kyung Woo Kim (National Marine Biodiversity Institute of Korea) ;
  • Ji-Yul Kim (National Marine Biodiversity Institute of Korea) ;
  • Jeong Min Lee (National Marine Biodiversity Institute of Korea) ;
  • Mi-jin Yim (National Marine Biodiversity Institute of Korea) ;
  • Dae-Sung Lee (National Marine Biodiversity Institute of Korea) ;
  • Gun-Woo Oh (National Marine Biodiversity Institute of Korea) ;
  • Hyun-Soo Kim (Deapartment of Seafood Science and Technology/Institute of Marine Industry, Gyeongsang National University)
  • 유철영 (경상국립대학교 해양식품공학과/해양산업연구소) ;
  • 장소리 ((주)동원F&B 생산팀) ;
  • 고석천 (국립해양생물자원관) ;
  • 김경우 (국립해양생물자원관) ;
  • 김지율 (국립해양생물자원관) ;
  • 이정민 (국립해양생물자원관) ;
  • 임미진 (국립해양생물자원관) ;
  • 이대성 (국립해양생물자원관) ;
  • 오건우 (국립해양생물자원관) ;
  • 김현수 (경상국립대학교 해양식품공학과/해양산업연구소)
  • Received : 2025.09.04
  • Accepted : 2025.10.10
  • Published : 2025.12.31
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Abstract

Seaweed-derived natural compounds are increasingly recognized for their potent antioxidant and skin-protective effects, offering a viable alternative to synthetic cosmetic ingredients. Oxidative stress accelerates skin aging by degrading collagen and hyaluronic acid, leading to reduced elasticity, increased wrinkle formation, and impaired moisture retention. This study investigated the antioxidant and anti-aging effects of Polysiphonia morrowii extract (PME), obtained using 70% ethanol-a red alga rich in polyphenols and flavonoids. The total polyphenol and flavonoid contents, DPPH and ABTS radical-scavenging activities, and inhibitory effects on collagenase, elastase, and hyaluronidase were evaluated. PME exhibited high polyphenol (95.79 ± 5.72 mg/g) and flavonoid (39.77 ± 0.68 mg/g) contents. It also demonstrated significant antioxidant activity, with IC50 values of 32.4 ± 0.11 ㎍/mL for the DPPH assay and 10.2 ± 0.17 ㎍/mL for the ABTS assay. Moreover, PME effectively inhibited collagenase (IC50 = 614.96 ± 1.55 ㎍/mL), elastase (IC50 = 140.63 ± 8.28 ㎍/mL), and hyaluronidase (IC50 = 11.02 ± 0.44 ㎍/mL), indicating strong anti-aging potential. These findings suggest that PME may help mitigate skin aging by modulating key enzymes involved in skin matrix degradation. Therefore, PME represents a promising natural and sustainable ingredient for anti-aging skincare and cosmetic formulations.

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Acknowledgement

이 논문은 2025년 국립해양생물관의 재원(2025M00500)으로 지원받아 수행된 연구입니다.