DOI QR코드

DOI QR Code

Growth performance of pigs fed low-protein diets supplemented with crystalline amino acids at different growth stages

  • Inho Cho (Department of Animal Science and Biotechnology, Kyungpook National University) ;
  • Changsu Kong (Department of Animal Science and Biotechnology, Kyungpook National University)
  • Received : 2024.05.20
  • Accepted : 2024.07.17
  • Published : 2025.02.01

Abstract

Objective: This study aimed to investigate the impact of reducing dietary crude protein (CP) coupled with supplementation of indispensable amino acids (AA) on growth performance of pigs at different growth stages. Methods: A total of 126 (63 barrows and 63 gilts), 90 (45 barrows and gilts), and 72 (36 barrows and 36 gilts) pigs with average weights of 9.8±1.62, 30.6±2.31, and 58.3±2.95 kg in the nursery, growing, and finishing stages, respectively, were assigned to three dietary treatments with six replicates in a randomized complete block design. The pigs had ad libitum access to water and fed three experimental diets, each supplemented with all indispensable AA and subjected to a 2% reduction in CP from the upper limits of 18%, 16%, and 16% established for the nursery, growing, and finishing stages, respectively. Results: In the nursery stage, from 0 to 2 weeks, reducing dietary CP concentrations decreased average daily feed intake (ADFI; linear, p = 0.04). From 2 to 4 weeks, dietary CP reduction decreased average daily gain (ADG; linear, p<0.01; quadratic, p = 0.02), ADFI (linear, p = 0.04), and gain-to-feed ratio (G:F; linear, p = 0.01). From 0 to 4 weeks, reduction in dietary CP concentrations decreased ADG (linear p<0.01), and G:F (linear, p = 0.01). In the growing stage, the dietary CP reduction did not affect growth performance. During the finishing stage, decrease in dietary CP concentrations decreased ADFI from 3 to 6 weeks (quadratic, p<0.01) and 0 to 6 weeks (quadratic, p = 0.01). Conclusion: Dietary CP reduction with indispensable AA supplementation potentially decreases the growth performance of nursery pigs but may not decrease the growth performance of growing and finishing pigs.

Keywords

Acknowledgement

The authors would like to thank Prof. Yoo Yong Kim for assistance throughout the experiment.

References

  1. Gloaguen M, Le Floc'h N, Corrent E, Primot Y, van Milgen J. The use of free amino acids allows formulating very low crude protein diets for piglets. J Anim Sci 2014;92:637-44. https://doi.org/10.2527/jas.2013-6514
  2. Florou-Paneri P, Christaki E, Giannenas I, et al. Alternative protein sources to soybean meal in pig diets. J Food Agric Environ 2014;12:655-60. https://doi.org/10.1234/4.2014.5214
  3. Giuliana P, Francesca T, Riccardo F, et al. Protein hunger of the feed sector: the alternatives offered by the plant world. Ital J Anim Sci 2020;19:1204-25. https://doi.org/10.1080/1828051X.2020.1827993
  4. NRC. Nutrient requirements of swine. 10th ed. Washington, DC, USA: National Academic Press; 1998.
  5. Dourmad JY, Jondreville C. Impact of nutrition on nitrogen, phosphorus, Cu and Zn in pig manure, and on emissions of ammonia and odours. Livest Sci 2007;112:192-8. https://doi.org/10.1016/j.livsci.2007.09.002 
  6. Cappelaere L, Grandmaison JLC, Martin N, Lambert W. Amino acid supplementation to reduce environmental impacts of broiler and pig production: a review. Front Vet Sci 2021;8:689259. https://doi.org/10.3389/fvets.2021.689259 
  7. Jha R, Berrocoso JFD. Dietary fiber and protein fermentation in the intestine of swine and their interactive effects on gut health and on the environment: a review. Anim Feed Sci Technol 2016;212:18-26. https://doi.org/10.1016/j.anifeedsci.2015.12.002
  8. Pluske JR, Pethick DW, Hopwood DE, Hampson DJ. Nutritional influences on some major enteric bacterial diseases of pig. Nutr Res Rev 2002;15:333-71. https://doi.org/10.1079/NRR200242
  9. Wheeler T, Reynolds C. Predicting the risks from climate change to forage and crop production for animal feed. Anim Front 2013;3:36-41. https://doi.org/10.2527/af.2013-0006
  10. World agriculture towards2030/2050: the 2012 revision [Internet]. Rom, Italy: Food and Agriculture Organization of the United Nations; c2012 [cited 2023 Nov 20]. Available from: https://ageconsearch.umn.edu/record/288998/?v=pdf
  11. Wang Y, Zhou J, Wang G, Cai S, Zeng X, Qiao S. Advances in low-protein diets for swine. J Anim Sci Biotechnol 2018; 9:60. https://doi.org/10.1186/s40104-018-0276-7 
  12. Corring T, Aumaitre A, Durand G. Development of digestive enzymes in the piglet from birth to 8 weeks: I. pancreas and pancreatic enzymes. Nutr Metab 1978;22:231-43. https://doi.org/10.1159/000176219 
  13. Elefson SK, Lu N, Chevalier T, et al. Assessment of visceral organ growth in pigs from birth through 150 kg. J Anim Sci 2021;99:skab249. https://doi.org/10.1093/jas/skab249 
  14. McConnell JC, Barth KM, Griffin SA. Nutrient digestibility and nitrogen metabolism studies at different stages of growth with fat and lean type swine fed two levels of protein. J Anim Sci 1971;32:654-7. https://doi.org/10.2527/jas1971.324654x 
  15. NRC. Nutrient requirements of swine. 11th ed. Washington, DC, USA: National Academic Press; 2012. 
  16. AOAC. Official methods of analysis of AOAC International. 20th ed. Gaithersburg, MD, USA: AOAC International; 2016. 
  17. Rezaei R, Knabe DA, Tekwe CD, et al. Dietary supplementation with monosodium glutamate is safe and improves growth performance in postweaning pigs. Amino Acids 2013;44:911-23. https://doi.org/10.1007/s00726-012-1420-x 
  18. Tuitoek K, Young LG, de Lange CFM, Kerr BJ. The effect of reducing excess dietary amino acids on growing-finishing pig performance: an elevation of the ideal protein concept. J Anim Sci 1997;75:1575-83. https://doi.org/10.2527/1997.7561575x
  19. Mavromichalis I, Webel DM, Emmert JL, Moser RL, Baker DH. Limiting order of amino acids in a low-protein cornsoybean meal-whey-based diet for nursery pigs. J Anim Sci 1998;76:2833-7. https://doi.org/10.2527/1998.76112833x
  20. Nyachoti CM, Omogbenigun FO, Rademacher M, Blank G. Performance responses and indicators of gastrointestinal health in early-weaned pigs fed low-protein amino acidsupplemented diets. J Anim Sci 2006;84:125-34. https://doi.org/10.2527/2006.841125x
  21. Wu G. Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition. J Anim Sci Biotechnol 2014;5:34. https://doi.org/10.1186/2049-1891-5-34
  22. Deng D, Yao K, Chu W, et al. Impaired translation initiation activation and reduced protein synthesis in weaned piglets fed a low-protein diet. J Nutr Biochem 2009;20:544-52. https://doi.org/10.1016/j.jnutbio.2008.05.014
  23. Fang LH, Jin YH, Do SH, et al. Effects of dietary energy and crude protein levels on growth performance, blood profiles, and nutrient digestibility in weaning pigs. Asian-Australas J Anim Sci 2019;32:556-63. https://doi.org/10.5713/ajas.18.0294
  24. He L, Wu L, Xu Z, et al. Low-protein diets affect ileal amino acid digestibility and gene expression of digestive enzymes in growing and finishing pigs. Amino Acids 2015;48:21-30. https://doi.org/10.1007/s00726-015-2059-1
  25. Le Bellego L, van Milgen J, Noblet J. Effect of high temperature and low-protein diets on the performance of growing-finishing pigs. J Anim Sci 2002;80:691-701. https://doi.org/10.2527/2002.803691x
  26. Morales A, Buenabad L, Castillo G, et al. Serum concentration of free amino acids in pigs of similar performance fed diets containing protein-bound or protein-bound combined with free amino acids. Anim Feed Sci Technol 2020;267:114552. https://doi.org/10.1016/j.anifeedsci.2020.114552
  27. Yi XW, Zhang SR, Yang Q, Yin HH, Qiao SY. Influence of dietary net energy content on performance of growing pigs fed low crude protein diets supplemented with crystalline amino acids. J Swine Health Prod 2010;18:294-300. https://doi.org/10.54846/jshap/642
  28. Zhao Y, Tian G, Chen D, et al. Effect of different dietary protein levels and amino acids supplementation patterns on growth performance, carcass characteristics and nitrogen excretion in growing-finishing pigs. J Anim Sci Biotechnol 2019;10:75. https://doi.org/10.1186/s40104-019-0381-2
  29. Souza FNC, Genova JL, Gregory CR, et al. Low- and highprotein diets supplemented up to the fourth limiting amino acid for genetic lines of grower-finisher pigs. Livest Sci 2023; 267:105144. https://doi.org/10.1016/j.livsci.2022.105144
  30. Song W, Wu Z, Li W, Li Y. Multiple amino acid supplementations to reduce dietary protein for pigs during early and late finisher periods under commercial conditions. J Sci Food Agric 2023;103:3205-9. https://doi.org/10.1002/jsfa.12438
  31. Li Q, Patience JF. Factors involved in the regulation of feed and energy intake of pigs. Anim Feed Sci Technol 2017;233: 22-33. https://doi.org/10.1016/j.anifeedsci.2016.01.001
  32. Sun Y, Teng T, Bai G, et al. Protein-restricted diet balanced for lysine, methionine, threonine, and tryptophan for nursery pigs elicits subsequent compensatory growth and has long term effects on protein metabolism and organ development and tryptophan for nursery pigs elicits subsequent compensatory growth and has long term effects on protein metabolism and organ development. Anim Feed Sci Technol 2020;270: 114712. https://doi.org/10.1016/j.anifeedsci.2020.114712
  33. Li Y, Wei H, Li F, et al. Supplementation of branched-chain amino acids in protein-restricted diets modulates the expression levels of amino acid transporters and energy metabolism associated regulators in the adipose tissue of growing pigs. Anim Nutr 2016;2:24-32. https://doi.org/10.1016/j.aninu.2016.01.0