Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Analysis of Nanostructures and Organogel Properties of Lecithin-Salts Mixtures

레시틴과 염들 혼합물의 나노구조체 및 유기젤 특성 분석

  • Na-Hyeon Kim (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Min-Seok Kang (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Ju-Yeon Kim (Department of Chemical Engineering, Kumoh National Institute of Technology) ;
  • Kyo-Chan Koo (Department of Management Engineering, Dankook University) ;
  • Hee-Young Lee (Department of Chemical Engineering, Kumoh National Institute of Technology)
  • 김나현 (국립금오공과대학교 화학공학과) ;
  • 강민석 (국립금오공과대학교 화학공학과) ;
  • 김주연 (국립금오공과대학교 화학공학과) ;
  • 구교찬 (단국대학교 경영공학과) ;
  • 이희영 (국립금오공과대학교 화학공학과)
  • Received : 2024.12.09
  • Accepted : 2025.01.09
  • Published : 2025.02.10
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Abstract

Lecithin, an amphiphilic surfactant, self-assembles into spherical reverse micelles in various organic solvents. When salts with low solubility in organic solvents interact with the hydrophilic head group of lecithin, their solubility increases significantly, triggering structural changes in the lecithin molecules. These changes induce the transformation of spherical reverse micelles into cylindrical reverse micelles, and as these cylindrical micelles form a network, significant changes in the rheological properties occur. In this study, two different salts are simultaneously added to lecithin solutions to investigate the formation of self-assembled nanostructures and the resulting rheological changes. Small-angle X-ray scattering (SAXS) and rheological analyses are employed to quantitatively examine the changes in the nanostructures' morphology and physical properties.

레시틴은 양친매성 특성을 갖는 인지질의 한 종류로, 다양한 유기용매 내에서 구형 역마이셀을 자가조립한다. 유기용매에서 용해도가 낮은 염들이 레시틴의 친수성 머리 부분과 상호작용하면, 이들 염의 용해도가 현저히 향상되며 레시틴 분자의 구조적 변화를 촉발한다. 이 변화는 초기 구형 역마이셀이 역실린더형 마이셀로 변형되도록 유도하고, 이러한 역실린더형 마이셀들이 네트워크를 형성하면서 점도 등의 유변학적 특성에 현저한 변화를 일으킨다. 본 연구에서는 레시틴 용액에 두 가지 염을 동시에 첨가하여, 자가조립 나노구조체의 형성 과정과 유변학적 특성 변화를 면밀히 조사한다. 이를 위해 소각 X선 산란(SAXS)과 유동계 분석법을 활용하여, 나노구조체의 형태와 물리적 특성 변화를 정량적으로 분석한다.

Keywords

Acknowledgement

본 과제(결과물)는 교육부와 한국연구재단의 재원으로 지원을 받아 수행된 3단계 산학연협력 선도대학 육성사업(LINC 3.0)의 연구결과입니다.

References

  1. J. N. Israelachvili, Intermolecular Surface Forces, 3rd ed., 540-549, Academic Press, San Diego, CA, USA (2011).
  2. D. F. Evans and H. Wennerstorm, The Colloidal Domain: Where Physics, Chemistry, Biology, and Technology Meet, 2nd ed., 78-80, New York, NY, USA (1999).
  3. K. Mukherjee, S. Moulik, and D. Mukherjee, Thermodynamics of micellization of aerosol OT in polar and nonpolar solvents. A calorimetric study, Langmuir, 9, 2838-1730 (1993).
  4. D. M. Willard, R. E. Riter, and N. E. Levinger, Dynamic of polar solvation in lecithin/water/cyclohexane reverse micelles, J. Am. Chem. Soc., 120, 4151-4160 (1998). https://doi.org/10.1021/ja980086k
  5. S. H. Tung, H. Y. Lee, and S. R. Raghavan, A facile route for creating "reverse" vesicles: Insights into "reverse" self-assembly inorganic liquids, J. Am. Chem. Soc., 130, 8813-8817 (2008). https://doi.org/10.1021/ja801895n
  6. H. Y. Lee, K. K. Diehn, S. W. Ko, S. H. Tung, and S. R. Raghavan, Can simple salts influence self-assembly in oil? Multivalent cations as efficient gelators of lecithin organosols, Langmuir, 26, 13831-13838 (2010). https://doi.org/10.1021/la1019108
  7. L. K. Shrestha, R. G. Shrestha, and K. Aramaki, Intrinsic parameters for the structure control of nonionic reverse micelles in styrene: SAXS and rheometry studies, Langmuir, 27, 5862-5873 (2011). https://doi.org/10.1021/la200663v
  8. M. G. Kim, E. J. Oh, K. S. Jin, J. W. Chang, and H. Y. Lee, Effect of sugar alcohols on the reverse self-assembly of lecithin in diverse organic solvents, J. Mol. Liq., 330, 115670 (2021). https://doi.org/10.1016/j.molliq.2021.115670
  9. C. Y. Lin and S. H. Tung, On the length of lecithin reverse wormlike micelles induced by inorganic salts: Binding site matters, J. Mol. Liq., 329, 115543 (2021).
  10. H. J. Lee, H. J. Kim, D. G. Park, K. S. Jin, J. W. Chang, and H. Y. Lee, Mechanism for transition of reverse cylindrical micelles to spherical micelles induced by diverse alcohols, Langmuir, 36, 8174-8183 (2020). https://doi.org/10.1021/acs.langmuir.0c01246
  11. S. T. Lin, C. S. Lin, Y. Y. Chang, A. E. Whitten, A. Sokolova, C. M. Wu, V. A. Ivanov, A. R. Khokhlov, and S. H. Tung, Effects of alkali cations and halide anions on the self-assembly of phosphatidylcholine in oils, Langmuir, 32, 12166-12174 (2016). https://doi.org/10.1021/acs.langmuir.6b03449
  12. E. J. Oh, D. G. Park, Y. S. Lim, K. S Jin, and H. Y. Lee, Structural transition of reverse cylindrical micelles to reverse vesicles by mixtures of lecithin and inorganic salts, J. Colloid Interface Sci., 615, 768-777 (2022). https://doi.org/10.1016/j.jcis.2022.02.015
  13. E. A. Chu, D. G. Park, E. J. Oh, Y. S. Lim, N. H. Kim, Y. M. Lee, K. S. Jin, J. H. Choi, and H. Y. Lee, Robust sugar alcohol with lecithin functionalities for sustainable gelation of edible oils, Food Biosci., 55, 103068 (2023). https://doi.org/10.1016/j.fbio.2023.103068
  14. Y. A. Shchipunov, Lecithin organogel: A micellar system with unique properties, Colloids Surf. A: Physicochem. Eng. Asp., 183-185, 541-554 (2001). https://doi.org/10.1016/S0927-7757(01)00511-8
  15. S. H. Tung, Y. E. Huang, and S. R. Raghavan, A new reverse wormlike micellar system: Mixtures of bile salt and lecithin in organic liquids, J. Am. Chem. Soc., 128, 5751-5756 (2006). https://doi.org/10.1021/ja0583766
  16. H. Y. Lee, K. K. Diehn, K. Sun, T. Chen and S. R. Raghavan, Reversible photorheological fluids based on spiropyran-doped reverse micelles, J. Am. Chem. Soc., 133, 8461-8463 (2011). https://doi.org/10.1021/ja202412z
  17. C. R. Lee, Y. K. Lee, E. J. Oh, K. S. Jin, H. Y. Lee, Effect of aliphatic solvents on the reverse self-assembly of lecithin and calcium chloride mixtures, J. Mol. Liq., 316, 113790 (2020). https://doi.org/10.1016/j.molliq.2020.113790
  18. C. A. Dreiss, Wormlike micelles: Where do we stand? Recent developments, linear rheology and scattering techniques, Soft Matter, 3, 956-970 (2007). https://doi.org/10.1039/b705775j
  19. L. A. Feigin and D. I. Svergun, Structure Analysis by Small-Angle X-Ray and Neutron Scattering, 1st ed., 94-98, Plenum Press, New York, NY, USA (1987).
  20. J. S. Pedersen, Analysis of small-angle scattering data from colloids and polymer solutions: Modeling and least-squares fitting, Adv. Colloid Interface Sci., 70, 171-210 (1997). https://doi.org/10.1016/S0001-8686(97)00312-6
  21. O. Glatter and O. Kratky, Small Angle X-Ray Scattering, 1st ed., 81-82, Academic Press, New York, NY, USA (1982).
  22. S. T. Lin, C. S. Lin, Y. Y. Chang, A. E. Whitten, A. Sokolova, C. M. Wu, V. A. Ivanov, A. R. Khokhlov, and S. H. Tung, Effects of alkali cations and halide anions on the self-assembly of phosphatidylcholine in oils, Langmuir, 32, 12166-12174 (2016). https://doi.org/10.1021/acs.langmuir.6b03449