• Title/Summary/Keyword: %24K_i%24

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A 24 GHz I/Q LO Generator for Heartbeat Measurement Radar System (심장박동 측정 레이더를 위한 24GHz I/Q LO 발생기)

  • Yang, Hee-Sung;Lee, Ockgoo;Nam, Ilku
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.11
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    • pp.66-70
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    • 2016
  • This paper presents an 24 GHz I/Q LO generator for a heartbeat measurement radar system. In order to improve the mismatch performance between I and Q LO signals against process variation, a 24 GHz I/Q LO generator employing a low-pass phase shifter and a high-pass phase shifter composed of inductors and capacitors is proposed. The proposed 24 GHz I/Q LO generator consists of an LO buffer, a low-pass phase shifter and a high-pass phase shifter. It was designed using a 65 nm CMOS technology and draws 8 mA from a 1 V supply voltage. The proposed 24 GHz I/Q LO generator shows a gain of 7.5 dB, a noise figure of 2.3 dB, 0.1 dB gain mismatch and $4.3^{\circ}$ phase mismatch between I and Q-path against process and temperature variations for the operating frequencies from 24.05 GHz to 24.25 GHz.

Expression and Characterization of catA1 (catechol 1,2-dioxygenase I1) of Acinetobacter lwoffii K24 in Escherichia coli

  • Kim, Seung-Il;Kweon, Soo-Mi;Kim, Soo-Hyun;Ha, Kwon-Soo
    • BMB Reports
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    • v.30 no.5
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    • pp.342-345
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    • 1997
  • Catechol 1,2-dioxygenase $I_1$ (CD $I_1$) gene of Acinetobacter Iwoffii K24, $catA_1$ was expressed in Escherichia coli and was partially purified by using a MonoQ column. Expressed CD $I_1$ had the same molecular weight as purified CD $I_1$ from A. Iwoffii K24 on SDS-PAGE. Expressed CD $I_1$ was also identified by Western blotting and peptide sequencing of N-terminal and internal regions. When compared with purified CD $I_1$ of A. Iwoffii K24, expressed CD $I_1$ had similar substrate specificities and the effects of compounds on enzyme activity. N-terminal amino acid sequence of CD I expressed in E. coli was the same as that of purified CD $I_1$, suggesting that CD $I_1$ may be under the same posttranslational processing in E. coli and A. Iwoffii K24.

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Optimal Imaging Time for Diagnostic I-123 Whole Body Scan in the Follow-up of Patients with Differentiated Thyroid Cancer: Comparison between 6- and 24-Hour Images of the Same Subjects (분화 갑상선 암의 추적 관찰에서 진단적 I-123 전신 스캔의 최적 영상 시점: 동일 환자에서 6시간과 24시간 영상의 비교)

  • Lee, Hong-Je;Lee, Sang-Woo;Song, Bong-Il;Kang, Sung-Min;Seo, Ji-Hyoung;Yoo, Jeong-Soo;Ahn, Byeong-Cheol;Lee, Jae-Tae
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.2
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    • pp.129-136
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    • 2009
  • Purpose: To determine optimal imaging time for diagnostic I-123 whole body scan in the follow-up of patients with differentiated thyroid cancer(DTC), we compared the image quality of 6- and 24-hour images of the same subjects. Materials and Methods: Four hundred ninety-eight patients(M:F = 55:443, Age $47.6{\pm}12.9$ years) with DTC who had undergone total thyroidectomy and I-131 ablation therapy underwent diagnostic whole body scanning 6 hour and 24 hour after oral ingestion of 185 MBq(5 mCi) of I-123. Serum thyroglobulin measurement and ultrasonography of the neck were performed at the time of imaging. In 40 patients underwent additional I-131 therapy, post-therapy I-131 images were obtained and compared with diagnostic I-123 images. Results: In 440 patients(88.4%), 6- and 24-hour diagnostic I-123 images were concordant, and 58 patients(11.6%) showed discordant findings. Among 58 discordant patients, 31 patients showed abnormal tracer uptake on only 6-hour image, which turned out false-positive findings in all cases. In 12 patients with positive findings on only 24-hour image, remnant thyroid tissue(4 patients) and cervical lymph node metastasis(3 patients) were presented. Among 40 patients underwent additional I-131 therapy, 6-hour and 24-hour images were discordant in 13 patients. All 5 patients with abnormal uptake on only 6-hour image revealed false-positive results, whereas most of 24-hour images were concordant with post-therapy I-131 images. Conclusion: I-123 imaging at 24-hour could reduce false-positive findings and improve diagnostic accuracy, compared with 6-hour image in the follow-up of patient with DTC.

A Study of the Construction in order to 24/25 I-NRZI Modulator Designs for DVCR (DVCR용 24/25 I-NRZI 변조기의 설계를 위한 구조 고찰)

  • Park, Jong-Jin;Kook, Il-Ho;Kim, Eun-Won;Cho, Won-Kyung
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.37 no.1
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    • pp.35-41
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    • 2000
  • This paper considers the consturction of 24/25 I-NRZI (Interleaved - Non Return to Zero Inverse) modulator designs for DVCR (Digital Video Cassette Recorder), and size of validity bit in order to store the amplitude value of square-wave and the standard data ( sine and cosine coefficients) at ROM Table that to acceptable the spectrum standard. The validity bit size of the standard data and the amplitude value of square-wave that to store at ROM Table are affected the size of pilot signal on the output spectrum, and the hardware size of modulator. At the designable 24/25 I-NRZI modulator, we simulated using random pattern (F0,F1,F2) that to verification the output data of the spectrum. Moreover, the resultant of the spectrum analysis, at the optimizing value, is 0.065 on the amplitude value of square-wave, and 3bit on the size of bit in order to store the standared data at ROM Table. In order to verify the hardware of designable 24/25 I-NRZI modulator, we perform to modeling of C-language firstly, and coding to Verilog HDL (Cadence Verilog XL) and synthesized using Synopsys (Library "Samsung KG75") tool as a base of spectrum results. In a foundation of this result, we are considered the size of hardware. In this paper, a considerable 24/25 I-NRZI modulator designable less than 10,000 gates as that is improved consturction as regards the path method of pre-coder etc, and able to application digital camcorders as now practical use.

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In Vivo Image and Biodistribution of $^{123}I$-15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (BMIPP) in Liposarcoma Bearing Nude Mice (지방육종형성 동물모델에서 $^{123}I$-15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid (BMIPP)의 생체분포와 생체영상)

  • Lee, Tae-Sup;Suh, Yong-Sup;Choi, Chang-Woon;Woo, Kwang-Sun;Chung, Wee-Sup;Lim, Soo-Jung;Lim, Sang-Moo;Awh, Ok-Doo
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.5
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    • pp.324-333
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    • 2001
  • Purpose: $^{123}I$-labeled fatty acids have been used in the evaluation of regional myocardial energy metabolism. This study aimed to evaluate the usefulness of $^{123}I$-BMIPP as a liposarcoma-imaging agent. Materials and Methods: We compared in vitro uptakes between liposarcoma(SW872) and glioma(9L) cell lines, and examined biodistribution and in vivo images of $^{123}I$-BMIPP in liposarcoma-bearing nude mice. Cold-BMIPP was labeled with $^{123}I\;using\;Cu^{2+}$ as catalyst. After purification by Sep-pak, radiochemical purity was determined by TLC. We compared cellular uptake between glioma and liposarcoma after incubation of 5, 10, 15, 30, 60, 120, and 180 mins with culture medium containing $^{123}I$-BMIPP. The difference in biodistribution was determined between non-feeding (water only) group for 18 hr and feeding group in normal mice (n=6/group) at 0.5, 2, and 24 hr. In liposarcoma-hearing nude mice model, liposarcoma, SW872, ceil lines were injected subcutaneously into the felt thigh of nude mice. The biodistribution of $^{123}I$-BMIPP was evaluated at 0.5, 2, and 24 hr (n:5 / group) and in vivo Image of $^{123}I$-BMIPP was obtained with gamma camera at 2 and 24 hr in liposarcoma-hearing nude mice. Results: Radiolabeling yield and radiochemical purity were 95% and above 99%, respectively. SW872 cell line showed more increased uptake than 9L with 1.5 times at 180 mins. The clearance of $^{123}I$-BMIPP in various tissues was more delayed in the non-feeding group than in the feeding group, especially at delayed time (24 hr) in normal mice, and the major excreting organ was the gastrointestinal tract. In liposarcoma-bearing nude mice, tumor/blood ratio of $^{123}I$-BMIPP was 0.94, 0.75, and 1.38 and tumor/muscle ratio was 0.66, 1.53, and 1.11 at 0.5, 2, and 24hr, respectively. $^{123}I$-BMIPP was selectively localized in liposarcoma at 24 hr image. Conclusions: These results suggest that $^{123}I$-BMIPP can be used as a liposarcoma-imaging agent.

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A Study on the Weldability of Magnesium Alloy by Laser Heat Source (I) - Comparison on Laser Weldability of AZ31B-H24 and AZ31B-O - (레이저 열원을 이용한 마그네슘 합금의 용접성에 관한 연구 (I) - AZ31B-H24 및 AZ31B-O의 레이저 용접성 비교 -)

  • Lee, Jung-Han;Kim, Jong-Do;Lee, Mun-Yong
    • Journal of Welding and Joining
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    • v.30 no.5
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    • pp.70-75
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    • 2012
  • This study is related to the laser weldability of AZ31B magnesium alloy, an all-purpose wrought alloy with good strength and ductility. In general, AZ31B is classified into AZ31B-H24 and AZ31B-O depending on temper designation. Thus, in this study, the laser weldability of AZ31B-H24 and AZ31B-O was investigated and compared. CW Nd:YAG laser was used to produce bead and butt joints. And the effects of welding conditions on the weldability of these joints were examined in detail. As a result of this study, AZ31B-H24 was found to have thinner oxide film and smaller grain size compared with AZ31B-O. Due to such difference, in bead welding, AZ31B-H24 had more wide welding range for full penetration compared with AZ31B-O. Furthermore, it was also confirmed that AZ31B-H24 and AZ31B-O have different welding conditions to obtain stable keyhole in butt welding.

Effect of Insulin-like Growth Factor-I and Cumulus Cells on In Vitro Maturation in Porcine Oocytes (돼지난자의 체외성숙시 Insulin-like Growth Factor-과 난구세포의 영향)

  • Park, C.K.;Cho, J.W.;Shin, M.K.;Cheong, H.T.;Yang, B.K.;Kim, C.I.
    • Korean Journal of Animal Reproduction
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    • v.23 no.4
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    • pp.323-331
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    • 1999
  • The effects of insulin-like growth factor-I (IGF-I) and cumulus cells during in vitro maturation in porcine oocytes were examined. When follicular oocytes were cultured in medium with different concentrations of IGF-I, maturation rates were 60, 61 and 62 and 72% for 0, 15 and l0ng/$m\ell$ IGF-I. In medium with 10ng/$m\ell$ IGF-I, maturation rates were not significantly difference between oocytes with (68%) and without (52%) cumulus cells during the culture. In medium with-out IGF-I, however, the maturation rates in oocytes with cumulus cells (63%) was significantly (P<0.05) higher than oocytes without cumulus cells (32%). On the other hand, when IGF-I was added for first 24 h period or later 24 h period of culture, maturation rates were higher in oocytes with (61 and 49%) that than without (49 and 45%) cumulus cells. In experiment used medium without fetal calf serum (FCS) and porcine follicular fluid (PFF), the maturation rates in oocytes with cumulus cells for 48 h (48 and 67%) or first 24 h (46 and 63%) period after culture were significantly (P<0.01) higher than in oocytes without cumulus cells (16 and 18%) in the presence or absence of IGF-I. These results indicated that cumulus cells is essential on maturation in vitro in porcine oocytes, but IGF-I can promote oocytes maturation of oocytes without cumulus cells in medium with FCS and PFF.

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Hormonal Changes in Cultured Medium on In Vitro Culture of Bovine Splenic Macrophages (소 비장 유래 Macrophage의 체외배양에 의한 배양액내 호르몬 변화)

  • Choi, Sun-Ho;Cho, Sang-Rae;Han, Man-Hye;Kim, Hyun-Jong;Yeon, Seong-Heum;Son, Dong-Soo;Kim, Young-Keun
    • Development and Reproduction
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    • v.8 no.2
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    • pp.113-117
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    • 2004
  • This study was performed to investigate the hormonal changes in cultured medium during in vitro culture of bovine splenic macrophages. Both pregnant and non-pregnant slaughterhouse spleen were obtained and the macrophages were separated and cultured for 24~120 hrs at 39$^{\circ}C$. Progesterone productions of pregnant group were higher than non-pregnant group for 24~96hrs and significantly higher for 120 hrs. The production of estradiol was higher in 24 hrs in pregnant group and no differences post 24 hrs. Insulin-like growth factor- I(IGF-I) production of pregnant was higher than non-pregnant group at all the culture time point. Inconclusion, splenic macrophages were able to produce peptides by in vitro culture and have important role for the successful pregnancy in bovine.

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