• Journal of Korean Neurosurgical Society
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• v.43 no.2
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• pp.79-84
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• 2008

Objective: The length of anterior-posterior commissure (AC-PC) in racial groups, age, gender of patients with deep brain stimulation (DBS) and pallidotomy were investigated. Methods: From January 1996 to December 2003, 211 patients were treated with DBS and pallidotomy. There were 160 (76%) Caucasians, 35 (17%) Hispanics, 12 (5%) Asians and 4 Blacks (2%). There were 88 males and 52 females in DBS-surgery group and 44 males, 27 females in pallidotomy group. Mean age was 58 year-old. There were 19 males and 19 females and mean age was 54.7 years in the control group. Measurements were made on MRI and @Target software. Results: The average AC-PC distance was 24.89 mm (range 32 to 19), which increased with aging until 75 years old in Caucasian and also increased with aging in Hispanic, but the AC-PC distance peaked at 45 years old in Hispanic. The order of AC-PC distance were $24.6{\pm}2$ mm in Caucasian, $24.6{\pm}2.24$ mm in Asian, 24.53 mm in Black, $23.6{\pm}1.98$ mm in Hispanic. The average AC-PC distance in all groups was 24.22 mm in female who was mean age of 56.35, 25.28 mm in male who was mean age of 60.19 and $24.5{\pm}2$ mm in control group that was excluded because of the difference of thickness of slice. According to multiple regression analysis, the AC-PC distance was significantly correlated with age, race, and gender. Conclusion: The AC-PC distance is significantly correlated with age, gender, and race. The atlas of functional stereotaxis would be depended on the Variation of indivisual brain that can influenced by aging, gender, and race.

• KSBB Journal
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• v.15 no.4
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• pp.370-374
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• 2000

Some bacterial strains isolated from activated sludges and media and type cultures were cultivated in a pharmaceutical wastewater and a paperboard wastewater and added during batch treatment of those wastewaters in order for these strains to increase the treatment efficiency. Bacillus sp(PC-3) isolated from the charcoal media of the pharmaceutical wastewater plant grew remarkably over there strains in that wastewater and the viable cell count after 24hr cultivation was $1.1{\times}10^6m/L$. Bacillus subtills KCTC 1028 a type strain grew best in the paperboard wastewater and the viable cell count after 24hr cultivation was $1.1{\times}10^7m/L$. Addition of PC-3 in a batch treatment of the pharmaceutical wastewater increased COD removal by 18% after 8 day. And addition of Bacillus subtills KCTC 1028 in a batch treatment of the paperboard wastewater increased COD removal by 14% only after 24hy Bacillus subtills DCTC 1028 was though to be able to be produced economically using alcohol distillery wastewaters from starch material.

• Natural Product Sciences
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• v.24 no.2
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• pp.99-102
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• 2018

This study investigated the effects of ombuoside, a flavonol glycoside, on dopamine biosynthesis in PC12 cells. Ombuoside at concentrations of 1, 5, and $10{\mu}M$ increased intracellular dopamine levels at 1 - 24 h. Ombuoside (1, 5, and $10{\mu}M$) also significantly increased the phosphorylation of tyrosine hydroxylase (TH) (Ser40) and cyclic AMP-response element binding protein (CREB) (Ser133) at 0.5 - 6 h. In addition, ombuoside (1, 5, and $10{\mu}M$) combined with L-DOPA (20, 100, and $200{\mu}M$) further increased intracellular dopamine levels for 24 h compared to L-DOPA alone. These results suggest that ombuoside regulates dopamine biosynthesis by modulating TH and CREB activation in PC12 cells.

• Korean Journal of Pharmacognosy
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• v.30 no.1
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• pp.79-83
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• 1999

The effects of coralyne, a protoberberine isoquinoline compound, on dopamine biosynthesis in PC12 cells were investigated. Coralyne decreased the dopamine content dose-dependently $(46.3%\;inhibition\;at\;20\;{\mu}M\;for\;24 hr).$ Dopamine content was lowered at 6 hr and reached minimal level at 24 hr after exposure to coralyne at $20\;{\mu}M.$ The decreased dopamine level was maintained up to 48 hr and recovered to the control level at about 72 hr. Tyrosine hydroxylase, the rate-limiting enzyme in the catecholamine biosynthesis, was also inhibited at $20\;{\mu}M\;of\;coralyne$ by 16.1% relative to control. These results suggest that the inhibition of tyrosine hydroxylase by coralyne with a single treatment might be partially contributed to the decrease in dopamine content in PC12 cells.

• The Journal of the Acoustical Society of Korea
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• v.19 no.3
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• pp.57-62
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• 2000

In recent, the innovative improvement of a internet and computing environment make users desire the capability of processing information in real time. In this paper we implement a PC-to-PC real time multi-user communication system on the internet environment using the efficient algorithm for a real time processing and the MFEG-4 CELP codec which can be used for a low bit-rate coding from 6 to 24kbps. The implemented system produces a compressed bit-streams with the MPEG-4 CEU Mode-I 18200bps mode. There is 5 frames for a package and 1 frame has 160 samples. We can use this system to communicate with 4 users simultaneously in real time. The system is designed and examined on the Windows operating system.

• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.351-356
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• 2009

Many isoquinoline alkaloids including berberine lower dopamine content by reducing tyrosine hydroxylase (TH) activity and aggravate L-DOPA-induced cytotoxicity in PC12 cells. In this study, the effects of berberine on 6-hydroxydopamine (6-OHDA)-induced cytotoxicity in PC12 cells and on unilateral 6-OHDA-lesioned rat models were investigated. Berberine at 10-30 ${\mu}M$ did not affect cell viability in PC12 cells. However, berberine at concentrations higher than $50{\mu}M$ caused cytotoxicity at 24 h. Berberine (10-50 ${\mu}M$) also enhanced 6-OHDA (10-50 ${\mu}M$)-induced cytotoxicity at 24 h compared to 6-OHDA alone with an apoptotic process. In addition, treatment with berberine (5 and 30 mg/kg, i.p.) for three weeks showed a dopaminergic cell loss in substantia nigra of 6-OHDA-lesioned rats: 30 mg/kg berberine was more intensive cytotoxic. The levels of dopamine were also decreased by berberine (5 and 30 mg/kg) in the ipsilateral substantia nigra of 6-OHDA-lesioned rats. These results suggest that berberine aggravated 6-OHDA-induced cytotoxicity in PC12 cells and treatment with berberine (5 and 30 mg/kg) in 6-OHDA-lesioned rats also enhanced the degeneration of dopaminergic cell death and the decrease in dopamine levels in substantia nigra. Therefore, the long-term L-DOPA therapeutic patients with isoquinoline compounds including berberine may need to be checked for the adverse symptoms.

• Journal of Animal Science and Technology
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• v.52 no.3
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• pp.167-174
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• 2010

The objectives of this study were to quantify the combination values of the principal components and factors calculated using body measurements of Hanwoo (Korean Cattle) and estimate their heritabilities. The technique of multivariate analysis was used to reduce a large number of variables to a smaller number of new variables and characterize cattle according to body shape. The analyses were performed using 1,979 cattle at 12 months of age and 936 cattle at 24 months of age. The data for the analyses was obtained from progeny tests performed on Korean Cattle for 6 years from 2003 to 2008. The phenotypic correlations among these traits were estimated to range from 0.32 to 0.90 at 12 months of age and from 0.21 to 0.82 at 24 months of age. The first principal components (PC1s) indicated a weighed average of overall body measurements, accounting for 99.91% of the total variation for both periods of test. The two first PCs had positive coefficients for all body measurements. The major sources of PC, such as chest girth (CG), body length (BL), rump height (RH), and wither height (WH) were similar for both test periods. The heritabilities for PC1, the first factor score (FS1), and the second factor score (FS2) were estimated by multivariate REML method. The estimated heritabilities for PC1, FS1, and FS2 were 0.33, 0.38, and 0.40, respectively, at 12 months of age and 0.26, 0.76, and 0.58 at 24 months of age. Further studies are needed to determine whether the heritabilities of FS1 and FS2 at 24 months of age were overestimated.

• Computers and Concrete
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• v.24 no.6
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• pp.571-578
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• 2019

This study aimed to investigate the permeable nature of pervious concretes (PC) through the moving particle simulation (MPS) method. In the simulation, the complex structure of a pervious concrete was virtually demonstrated as a lattice model (LM) of spherical beads, where the test of permeability was conducted. Results of the simulation were compared with the experimental ones for validation. As a result, MPS results showed the permeability index of the LM as almost twice as big as the actual PCs. A proposed virtual model was created to prevent the stuck of water flow in the MPS simulation of PC or LM. Successful simulation results were demonstrated with the model.

• Journal of the Mineralogical Society of Korea
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• v.24 no.1
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• pp.19-29
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• 2011

Clay mineral assemblages of core PC25A collected from the northern part of the Aleutian Basin in the Bering Sea were examined in order to investigate changes in sediment provenances and transport pathways. Ages of core PC25A were determined by both Last Appearance Datum of radiolaria (L. nipponica sakaii; $48.6{\pm}2\; ka$) and age control points obtained by the correlations of $a^{\ast},\; b^{\ast}$, and laminated sediment layers with the adjacent core PC23A, whose ages are well constrained. The corebottom age of core PC25A was calculated to be about 57,600 yr ago and core-top might be missing during coring execution. Average contents of smectite, illite, kaolinite, and chlorite during the last glacial period are 11% (5~24%), 47% (36~58%), 13% (9~19%), and 29% (21~40%), respectively. Clay mineral assemblages of the last glacial period are characterized by higher illite and lower smectite contents than those of core MC24 representing the modern values. Illite-rich clay sediments during the warm Early Holocene were transported from the northern part of Alaska continent (Province 1) through the ice-melt waters. During the deglacial period (B${\phi}$lling-All${\phi}$rod) of MIS 2, clay-sized particles seemed to be also transported by ice-melt waters mainly from Province 2 and Province 3 located farther south than Province 1. Higher smectite content during the Last Glacial Maximum is attributed to increased amounts of clay particles from the adjacent Alaska Peninsula (Province 4). From the early to the middle MIS 3, illite and smectite contents decreased, whereas chlorite content increased. With the low sea level standing during MIS 3 the supply of clay sediments from Province 2 and Province 3 was most likely intensified. Changes in clay mineral assemblages of core PC25A located in the northern part of the Aleutian Basin in the Bering Sea are closely related to the change of surface current system caused by sea level variation during the last glacial period.

• Polymer(Korea)
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• v.37 no.6
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• pp.694-701
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• 2013

A new copolymer named T-TI24T (poly((5,5-(2-butyl-5,6-bisdecyloxy-4,7-di-thiophen-2-yl-isoindole-1,3-dione))- alt-(2,5-thiophene))) based on phthalimide derivative and thiophene is synthesized by the Stille-coupling reaction. The polymer shows relatively high number average molecular weight of 86500 g/mol with good solubility in common organic solvents such as chloroform, 1,2-dichlorobenzene, and toluene and is thermally stable up to $380^{\circ}C$. Besides, it possesses a relatively low highest occupied molecular orbital (HOMO) energy level of -5.33 eV, promising the high open circuit voltage ($V_{oc}$) for photovoltaic applications. Active layer solution of polymer T-TI24T-as a donor and (6)-1-(3-(methoxycarbonyl)- {5}-1-phenyl[5,6]-fullerene (PCBM)-as an acceptor in different weight ratios is applied to fabricate the polymer solar cell devices. The ratio of polymer/PCBM affects the solar cell efficiency and the best performance exhibits in the device with polymer/PCBM = 1:3 (w/w), which shows a power conversion efficiency (PCE) of 0.199% and a $V_{oc}$ of 0.99 V, respectively. Even though the device shows the very low PCE, the $V_{oc}$ is higher than that of well known bulk heterojunction type solar cell based on P3HT:PC61BM (c.a. 0.5 V).