• Title/Summary/Keyword: 강성

Search Result 9,463, Processing Time 0.037 seconds

Effects of Acori Rhizoma water extract on the Cerebral Cortex Neuron injured by Glucose Oxidase (석창포(石菖蒲) 전탕액(煎湯液)이 Glucose Oxidase에 의해 손상(損傷)된 대뇌피질(大腦皮質) 신경세포(神經細胞)에 미치는 영향(影響))

  • Choi, Kong-Han;Park, Seung-Taeck;Ryu, Do-Gon;Choi, Min-Ho;Hea, Jin-Young;Kang, Sung-Do;Go, Jeong-Soo;Yang, Sang-cheal;Sung, Yeun-Kyung;Cho, Nam-Su;Lee, Chun-Woo;Sou, Eui-Suk;Ryu, Young-Su
    • Journal of Oriental Physiology
    • /
    • v.14 no.2 s.20
    • /
    • pp.117-126
    • /
    • 1999
  • The purpose of this study is to examine the toxic effects caused by Glucose Oxidase(GO) and the effects of herbal extracts such as Acori Rhizoma(AR) on the treatment of the toxic effects. For this purpose, experiments with the cultured cell from the cerebrums of new born mice were done. The results of these experiments were as follows. 1. GO, a oxygen radical, decreased the survival rate of the cultured cells on NR assay and MTT assay. 2. GO, a oxygen radical, decreased the amount of neurofilaments and total protein. 3. AR have efficacy of increasing the amount of neurofilament. 4. AR have efficacy of increasing the amount of total protein. From the above results, It is concluded that AR has marked efficacy as a treatment for the damages caused in the GO-mediated oxidative process. And AR is thought to have certain pharmacological effects on controlling over aging. Further clinical study of this pharmacological effects of AR should be complemented.

  • PDF

Effects of Jagamchotang on the Cultured Rat Neonatal Myocardial Cells (자감초탕(炙甘草湯)이 배양심근세포(培養心筋細胞)에 미치는 영향(影響))

  • Lee, Lae-Chun;Cho, Nam-Su;Cho, Dong-Ki;Eom, Sang-Sup;Kang, Sung-Do;Lee, Chun-Woo;Go, Jeong-Soo;Sung, Yeun-Kyung;Lee, Kwan-Hyung;Sung, Ki-Ho;Park, Jun-Su;Ryu, Do-Gon;Moon, Byung-Sun
    • Journal of Oriental Physiology
    • /
    • v.14 no.2 s.20
    • /
    • pp.179-187
    • /
    • 1999
  • To investigate how Jagamchotang provent cellular injury by a certain starting point on reperfusion injury after ischemia in myocardial cell, conducted MTT assay, LM stydy and measured LDH secretion, heart rate and nitric oxide(NO), and got the following results. 1. Jagamchotang did not injure cells even in $20{\mu}g/ml$. 2. Jaganchotang repressed the toxicity of mitochondria and cell membrane in reperfusing after ischemia and repressed the contraction of promontory of myocardial cell and reduction of the number of cells. Also maintained regular heart rate and reduced the number of heart rate. 3. Synthesis of NO by Jagamchotang in ischemia increased 1.9 times than a control. 4. When reperfusing with sodium nitropruside (SNO), NO donor in ischemia repressed the toxicity of mitochondria as the case of reperfusing with Jagamchotang in ischemia. Therefore, putting these findings together, it. can be said the effect of Jagamchotang in ischemia will be closely related with generation of NO.

  • PDF

Exposure to Dithiopyr Alters Swimming Performance Parameters in Zebrafish (Dithiopyr에 노출이 zebrafish의 유영 행동에 미치는 영향)

  • Oh, Junyoung;Park, Eun-Jin;Kang, Seongeun;Lee, Seungheon
    • Journal of Life Science
    • /
    • v.26 no.2
    • /
    • pp.181-189
    • /
    • 2016
  • The aim of this study was to identify the effects of dithiopyr (DTP), a herbicide, on behavior in zebrafish. The toxicity of DTP has rarely been investigated in fish. In the present study, zebrafish were exposed to different concentrations of DTP in the range of 10-20 μM for 48 h in a test container, in order to measure the value of median lethal concentrations (LC50). Behavioral experiments were performed, including the novel tank test (NTT) and the open field test (OFT), to assess stress responses or locomotion. After exposure to the DTP solution at a sublethal concentration of 2.5–10 μM for 6 min, the behavior of the zebrafish was observed for 6 min. In the acute toxicity test, the LC50 value of DTP showed as 14.49 μM in the zebrafish. The NTT showed that the duration of immobility and the velocity were significantly increased by exposure at a concentration of 5 μM of DTP, compared with a control group (p<0.05). However, compared with the control group, DTP significantly decreased the distance moved and the frequency at the top of the tank, and significantly increased the turn angle and duration at the bottom, in a concentration-dependent manner (p<0.05). In addition, in the OFT, exposure to DTP significantly decreased the distance moved and velocity compared with the control group (p<0.05). Exposure to DTP also significantly increased the duration of immobility, the turn angle, and the meandering movement, in a concentration-dependent manner (p<0.05). Further, exposure to DTP at a low concentration elevated whole-body cortisol levels in the zebrafish. The results of this study thus suggest that DTP induces a toxic response and negative effects on behavior and the endocrine system in zebrafish.

Effects of Dietary Supplementation of a New Probiotic CS61 Culture on Performance in Broiler Chickens (새로운 생균제 CS61 배양액의 사료 내 급여가 육계의 생산성에 미치는 영향)

  • Kim, Sung-Hwan;Lee, In-Chul;Baek, Hyung-Seon;Kang, Seong-Soo;Kim, Hyoung-Chin;Yoo, Jin-Cheol;Kim, Jong-Choon
    • Journal of Life Science
    • /
    • v.22 no.3
    • /
    • pp.340-346
    • /
    • 2012
  • Bacterial resistance to antibiotics and residues of antibiotics in poultry products have encouraged the use of probiotics, prebiotic substrates, and synbiotic combinations of prebiotics and probiotics as alternative approaches to the use of antibiotics in poultry. The present study was carried out to evaluate the effect of a new probiotic CS61 culture on growth performance, feed conversion efficiency, and safety in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Two dosages of CS61 culture (0.1% and 1%) were fed to chickens for 28 days. The results showed that terminal body weight and daily weight gain in the treatment groups increased in a dose-dependent manner when compared with the control group. Dietary supplementation with CS61 culture also improved feed conversion rate compared to the control group. There were no treatment-related toxic effects in terms of clinical findings, mortality, necropsy findings, hematology, or serum biochemistry parameters in any group tested. The nitric oxide assay showed that CS61 peptide has a dose-dependent inhibitory effect on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells. The results of this experiment indicated that dietary supplementation of CS61 culture may improve growth performance and feed conversion efficiency in chickens through its anti-inflammatory effect.

Screening and Identification of Alkaline Protease Inhibitor-Producing Marine-derived Actinomyces. (Alkaline protease inhibitor를 생산하는 해양유래 방선균의 탐색 및 동정)

  • Kang, Sung-Il;Kong, Jai-Yul;Choi, Yeung-Joon;Kim, Min-Yong;Son, Hong-Joo
    • Journal of Life Science
    • /
    • v.18 no.4
    • /
    • pp.482-487
    • /
    • 2008
  • In this study, we screened and identified the bacterial strain showing high alkaline pretense inhibitor activity from marine environment. Nine bacterial strains with alkaline pretense inhibitor activity were isolated from marine sediments. Among them, strain C12 had the highest alkaline pretense inhibitor activity and was selected for further taxonomical study. On the basis of morphological and physiological characteristics, strain C12 was identified as the genus Streptomyces. A phylogenetic analysis of the 165 rDNA showed that the isolated strain was actually a member of the genus Streptomyces, because the determined sequence exhibited a higher homology with Streptomyces thermocarboxydus. Morphological characteristics showed cylindrical spore chain and smooth spore surface by scanning electron microscope. Strain C12 was grown on all media except for ISP 9 agar. This strain could be grown in the medium containing up to 9% NaCl.

The Ultra-Centrifuge Rotordynamics (초고속 원심분리기의 회전체동역학 설계)

  • 이안성;김영철;박종권
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 1996.10a
    • /
    • pp.319-323
    • /
    • 1996
  • \ulcorner\ulcorner\ulcorner\ulcorner 80,000 rpm \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner(ultra-centrifuge)\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner. \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner(critical speed)\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner(separation margin)\ulcorner \ulcorner\ulcorner, \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner-\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner. \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner \ulcorner\ulcorner\ulcorner, \ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner(extra slender shaft)\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner. \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner, \ulcorner\ulcorner 1\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner(bumper ring) \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner(guide bearing)\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner. \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner(finite element method)\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner, \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner\ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner \ulcorner\ulcorner\ulcorner \ulcorner\ulcorner(damping)\ulcorner \ulcorner\ulcorner\ulcorner\ulcorner.

  • PDF

Measurement of Width and Step-Height of Photolithographic Product Patterns by Using Digital Holography (디지털 홀로그래피를 이용한 포토리소그래피 공정 제품 패터닝의 폭과 단차 측정)

  • Shin, Ju Yeop;Kang, Sung Hoon;Ma, Hye Joon;Kwon, Ik Hwan;Yang, Seung Pil;Jung, Hyun Chul;Hong, Chung Ki;Kim, Kyeong Suk
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.36 no.1
    • /
    • pp.18-26
    • /
    • 2016
  • The semiconductor industry is one of the key industries of Korea, which has continued growing at a steady annual growth rate. Important technology for the semiconductor industry is high integration of devices. This is to increase the memory capacity for unit area, of which key is photolithography. The photolithography refers to a technique for printing the shadow of light lit on the mask surface on to wafer, which is the most important process in a semiconductor manufacturing process. In this study, the width and step-height of wafers patterned through this process were measured to ensure uniformity. The widths and inter-plate heights of the specimens patterned using photolithography were measured using transmissive digital holography. A transmissive digital holographic interferometer was configured, and nine arbitrary points were set on the specimens as measured points. The measurement of each point was compared with the measurements performed using a commercial device called scanning electron microscope (SEM) and Alpha Step. Transmission digital holography requires a short measurement time, which is an advantage compared to other techniques. Furthermore, it uses magnification lenses, allowing the flexibility of changing between high and low magnifications. The test results confirmed that transmissive digital holography is a useful technique for measuring patterns printed using photolithography.

A Study for a Near-Field Microwave Microscope Using a Tuning Fork Distance Control System in liquid Environment (튜닝폭 거리조절 센서를 이용한 근접장 마이크로파 현미경의 수중 측정을 위한 연구)

  • Kim, Song-Hui;Yoo, Hyung-Keun;Babajanyan, Arsen;Kim, Jong-Chul;Lee, Kie-Jin
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.27 no.4
    • /
    • pp.345-353
    • /
    • 2007
  • We have obtained a topographical image nondestructively for a Cu thin film in liquid using a near-field scanning microwave microscope (NSMM), its operating frequency was 3.5 to 5.5 GHz. We have kept a distance of 10 nm between tip and sample using a quartz tuning fork shear force feedback system. As an end of tip was attached to one prong of the quartz tuning fork has a length of 2 mm, the only tip of tuning fork was immersed in water tank. A loss cause by evaporation in water tank is regulated with actuator was connected to a supplementary tank. Moreover, using a revise program of LabView, we could increase the accuracy of a measurement in liquid.

Effect of Planting Site and Direction of Fruiting on Fruit Frost Damage in Persimmon (Diospyros kaki 'Fuyu') Fruits from Environment-friendly Orchard (친환경 과원의 단감 '부유'(Diospyros kaki 'Fuyu') 과실의 동상해에 미치는 나무의 식재위치와 착과방향의 영향)

  • Kang, Sung-Ku;Ahn, Kwang-Hwan;Choi, Seong-Tae;Do, Kyung-Ran;Cho, Kwang-Sik
    • Korean Journal of Organic Agriculture
    • /
    • v.22 no.4
    • /
    • pp.789-799
    • /
    • 2014
  • We have analyzed the effect of planting site (elevation) and direction of fruiting on the frost damage (tolerance to transparent skin and blemishes) of persimmon (Diospyros kaki Thunb) 'Fuyu' fruit subjected to the early fall frost (November 2, 2012) in environment-friendly orchards of Changnyeong and Changwon (Gyeongsangnam-do Korea). In Changnyeong, the direction of fruiting showed a significant effect on the fruit weight and the fruit width (p<0.01), and the fruit firmness (p<0.05) while the planting site (elevation) did a highly significant effect on the fruit width and the frost damage (p<0.01), and fruit length (p<0.05). In particular, severe frost damage of fruit (15.2%) and leaves (about 90%) was observed in the plants located in the low elevation area of orchard. The damaged fruit had an transparent skin color and/or blemishes. In Changwon, there was no effect of the planting site and the direction of fruiting on the frost damage, and the fruit characteristics except the fruit width having been related to the planting site (p<0.05). So, the main effects for the fruit frost damage was a terrain factor around the orchards.

Characteristics of Nutrient Distribution by the Natural and Artificial Controlling Factors in Small Stream Estuary (소하천 하구(남해 당항포)에서 자연적, 인위적 요인이 영양염 분포에 미치는 영향)

  • KANG, SUNGCHAN;PARK, SOHYUN;AN, SOONMO
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
    • /
    • v.22 no.1
    • /
    • pp.1-17
    • /
    • 2017
  • This study was conducted to investigate the nutrient distribution and controlling factors in small stream estuaries. The seasonal variations of nutrient concentration (nitrate, ammonium and phosphate) were observed from 2010 to 2012 in the three streams located in Dang-hang (closed estuary: Go-seong, open estuary: Gu-man and Ma-am). The nutrient concentrations in Go-seong were significantly higher than other estuaries, because Go-seong is relatively large and has large nutrient load from the watershed. The dyke located at the estuary, also, caused the high nutrient concentration by reducing the dilution and increasing residence time. In all three streams, nitrate concentration was high at upstream and decreased toward the downstream, because high load of nutrient input were located at upstream. Dilution and biogeochemical removal toward the downstream also caused the trends. Especially, denitrification, a typical nitrogen removing process showed clear tendency of gradual decreasing from upstream to downstream. However, Ammonium and phosphate concentrations were high at upstream and decreased toward the downstream only when the nutrient loads from the rivers were high. Nutrient concentrations were low in summer and high in winter. Freshwater discharge in summer caused a decrease of the residence time and increase of the transport of nutrients to downstream and reduced the nutrient concentrations in the estuary. Nutrient removal by the biological production during high temperature periods also affected the low nutrient concentrations. Small stream estuaries showed distinct nutrient dynamics. It is necessary to understand these characteristics in order to properly manage the small stream estuary.