• Title/Summary/Keyword: 폐경

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The Association between Bone Mineral Density, Bone Turnover Markers, and Nutrient Intake in Pre- and Postmenopausal Women (폐경 전.후 여성의 골밀도 및 골대사 지표에 영향을 미치는 요인)

  • Park, Ji-Youn;Choi, Mi-Youn;Lee, Seon-Heui;Choi, Yoon-Ho;Park, Yoo-Kyoung
    • Journal of Nutrition and Health
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    • v.44 no.1
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    • pp.29-40
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    • 2011
  • The purpose of this study was to examine the association among bone mineral density (BMD), biochemical bone markers, nutrients, and salt intake in premenopausal and postmenopausal women. We evaluated 431 subjects who visited a health promotion center of a university hospital between January 2008 and July 2009. We excluded those who were taking medications or who had an endocrine disorder affecting osteoporosis. The subjects were divided into premenopausal (n = 283) and postmenopausal (n = 143) women. We evaluated the correlation among BMD of the lumbar spine, femoral neck, and total femoral, as well as biochemical bone markers, hormone, serum profiles, general characteristics, nutrient intakes, and food intake frequencies. From a stepwise multiple regression analysis, lumbar spine BMD was positively correlated with weight (p < 0.001) and negatively correlated with osteocalcin (OC)(p < 0.001), Femoral neck BMD was positively correlated with weight (p < 0.001) and negatively correlated with C-telopeptide (CTx) and alkaline phosphatase (ALP)(p < 0.001, p < 0.05). In premenopausal women, femoral total BMD was positively correlated with BMI (p < 0.001) and negatively correlated with CTx (p < 0.001). In postmenopausal women, lumbar spine BMD was positively correlated with calcium intake (p < 0.01) and negatively correlated with sodium intake (p < 0.01). Femoral neck and femoral total BMD were both positively correlated with weight (p < 0.001), and femoral neck BMD was negatively correlated with age and ALP (p < 0.001, p < 0.05). Femoral total BMD was negatively correlated with age and OC (p < 0.001, p < 0.01). These results suggest that reducing sodium intake may play an important role delaying bone resorption and preventing a decrease in BMD.

Differential Association of History of Premenstrual Syndrome/Premenstrual Dysphoric Disorder with Vasomotor Symptoms According to Menopausal Stage (폐경 단계에 따른 월경전 증후군/월경전 불쾌장애의 과거력과 혈관운동증상의 차별적 연관성)

  • Hyun, Hong-Dae;Joe, Sook-Haeng;Jeong, Hyun-Ghang;Ko, Young-Hoon;Kwon, Eunjoo;Kim, Hyekyeong;Ko, Seung-Duk
    • Korean Journal of Psychosomatic Medicine
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    • v.23 no.1
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    • pp.57-65
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    • 2015
  • Objectives:Within the normal reproductive cycles of women, dramatic fluctuations of sexual hormones occur in the premenstrual and menopausal periods. In both periods, women are vulnerable to mood disturbances and show several somatic complaints. Based on these common clinical profiles and physiological changes, a relationship between vasomotor symptoms and the premenstrual syndrome has been suggested. However, attempts to establish such a link have yielded inconclusive results. The purpose of this study was to investigate the association between histories of premenstrual syndrome and menopausal vasomotor symptoms within different menopausal stages. Methods:This cross-sectional study recruited Korean women aged 45-64 years who were perimenopausal and postmenopausal from 16 branch offices of the Korean Association of Health Promotion. All subjects completed self-report questionnaires that asked about a history of premenstrual syndromes, vasomotor symptoms, and several other variables. Results:A total of 1054 participants(361 perimenopausal women and 693 postmenopausal women) completed the study. Severity of premenstrual symptoms significantly correlated with postmenopausal vasomotor symptoms, only in late perimenopausal(r=0.213, p=0.010) and early postmenopausal women(r=0.246, p<0.001). After adjusting for several factors related to vasomotor symptoms, a history of premenstrual syndrome was a significant predictor of moderate to very severe vasomotor symptoms in late perimenopausal(OR=5.197, p=0.005) and early postmenopausal women(OR=3.017, p=0.010). Conclusions:This study suggests that a history of premenstrual syndrome/premenstrual dysphoric disorder is differentially associated with vasomotor symptoms in the menopausal stage. Prospective studies with larger population are needed to confirm these findings

Risk Factors Affecting Severity of Menopausal Symptoms in Early and Late Postmenopasusal Woman (초기와 후기 폐경후기 여성에서의 폐경기 증상의 심각도와 위험 요인들)

  • Kim, Jong-Hun;Lee, Moon-Soo;Yang, Jae-Won;Ko, Young-Hoon;Ko, Seung-Duk;Joe, Sook-Haeng
    • Korean Journal of Psychosomatic Medicine
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    • v.17 no.2
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    • pp.52-61
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    • 2009
  • Objectives : The aim of this study was to assess health-related quality of life and evaluate the risk factors affecting severity of menopausal symptoms in early and late postmenopausal women based on the stages of reproductive aging workshop(STRAW) paradigm. Methods : This cross-sectional study examined 497 Korean postmenopausal women aged 41-59 years in Seoul and Gyeonggi province. We divided subjects into early postmenopause group and late postmenopause group. Menopause Rating Scale(MRS) was used to measure the quality of life. MRS scores, sociodemographic variables, smoking, alcohol use, age at menopause, and risk factors such as attitude to menopause, depression, history of premenstrual dysphoric disorder were compared between early and late postmenopause groups. Multiple regression analysis was performed in each group to assess the independent contribution of several variables. Results : Early postmenopause group showed significantly higher MRS scores, more negative attitude toward menopause, higher scores of depressive symptoms than late postmenopause group. Moderate to very severe hot flush group showed significantly, more negative attitude toward menopause, higher score of depressive symptoms, and higher MRS scores than none to mild hot flush groups. Depressive symptoms and attitude toward menopause contributed to the severity of menopausal symptom in both early and late postmenopause groups. Chronological age, age at menopause, history of PMDD contributed to severity of menopausal symptoms in early postmenopause group while marital status and occupation contributed in late postmenopause group. Conclusion : Health-related quality of life in postmenopause women was significantly lower in early postmenopause group than the late. Attitude toward menopause and depressive symptoms contributed significantly to quality of life in both early and late postmenopause groups but other variables contributed differently in each group. Further studies on clinical samples of postmenopausal women in order to confirm quality of life and its risk factor are needed to be done.

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Characteristics of the Health Factors in 45~60 Year Old Korean Women related to Menopausal Stages - Based on 2008~2009 Korean National Health and Nutrition Examination Survey - (2008~2009년 국민건강영양조사를 활용한 45~60세 한국여성의 폐경 여부에 따른 건강인자 특성)

  • Lee, Hye-Jin;Cho, Kwang-Hyun;Lee, Kyung-Hea
    • Korean Journal of Community Nutrition
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    • v.17 no.4
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    • pp.450-462
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    • 2012
  • We analyzed data from the combined 2008~2009 Korean National Health and Nutrition Examination Survey (KNHANES) to compare the health factors related to menopausal stages in 45~60 year old Korean women. In this study, we classified the subjects into a premenopausal group (n = 439) and a postmenopausal group (n = 683). In the postmenopausal group, age was higher (p < 0.001), monthly income (p < 0.01) and education levels (p < 0.001) were significantly lower than in the premenopausal group. Body fat % and waist circumferences were also higher in the postmenopausal group than in the premenopausal group. The serum glucose (p < 0.05), total cholesterol (p < 0.001), LDL-cholesterol (p < 0.001), triglyceride (p < 0.001), GOT (p < 0.001), GPT (p < 0.001) in the postmenopausal group were higher than in the premenopausal group. The postmenopausal group showed a significantly lower quality of life compared to the premenopausal group (p < 0.01). With regard to dietary quality, nutrient adequacy ratio (NAR) of vitamin A, vitamin $B_1$, vitamin $B_2$ and niacin in the postmenopausal group were significantly lower than in the premenopausal group. The levels of glucose, total cholesterol, LDL-cholesterol, and triglyceride showed a significantly positive correlation with age, waist circumferences, body fat % and BMI. The 45~60 year old Korean women in this study showed high levels of obesity and serum lipids. Also, intakes of the vitamins and minerals of the women did not meet the level of Dietary reference intakes for Koreans. Therefore, nutritional risk may be high in the women, especially in postmenopausal women. In order to prevent the health risk, women's health care including the quality of the meal should be considered.

The Relationship between Menopausal Symptoms, Perceived Awareness of Menopausal Symptom, Menopausal Attitude and Menopausal Management in Middle Age Women (중년여성의 폐경 증상, 폐경증상에 대한 주관적 인식, 폐경태도 및 폐경관리와의 관계)

  • Kim, Sung Ju;Kim, Young Ran;Lee, Ok Suk;Choi, So Young
    • Journal of the Korea Convergence Society
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    • v.12 no.2
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    • pp.347-356
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    • 2021
  • The purpose of this study was to investigate the correlation between menopausal symptoms, perceived awareness of menopausal symptom, menopausal attitude and of menopausal management in middle aged women and to identify factors affecting menopausal symptoms. The subjects of study were 242 middle aged women who are living in G, J, K city and understood the research items and agreed to participate in the research. Data were collected from April 10 to May 30, 2019. Data were analyzed using t-test, ANOVA, Pearson's Correlation Coefficient and Stepwise Multiple Regression with SPSS/WIN 25.0. In this study, it was founded that perceived awareness of menopausal symptom(β=. 51, p<.001), menstruation status(β=. 23, p<.001), perceived health status(β=. 19, p=. 002), satisfaction of life(β=. 14, p=. 019) and religion(β=. 10, p=. 045) were found to be influential factors affecting menopausal symptoms in middle aged women. The most influential factor was perceived awareness of menopausal symptom. A nursing intervention program is needed to change positively the awareness of menopausal symptom.

The Difference of Predictor of Bone Mineral Density in Pre and Postmenopausal Women (폐경에 따른 골밀도 예측인자의 차이)

  • Kim, Mi-Young;Kim, Hwa-Sun
    • Journal of radiological science and technology
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    • v.34 no.3
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    • pp.195-201
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    • 2011
  • We studied the relationship between prediction parameters and bone mineral density for pre-and-post menopausal women. We measured BMI%Fat by BIA, blood pressure and lipid profiles for 483 adult women who are in NPO state. SBP, TC, TG, LDL have significant statistical value in the postmenopause women group and postmenopause woman. The value of postmenopause women of these parameters are lower than premenopause woman. BMD has the most strongest relationship with LBM. The BMD and LDL level of postmenopause women have statistically negative relationship. The results show that for the premenopause cases, weight, BF, and HDL level were the major factors which affect the BMD. For postmenopause cases, however, weight, age, and LDL level turned out to be the most significant factors.

The Effects of Menopause on the Metabolic Syndrome in Korean Women (폐경이 대사증후군에 미치는 영향)

  • Bang, SoYoun;Cho, IlGu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2704-2712
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    • 2015
  • This study was the secondary analysis using the Korea National Health and Nutrition Examination Survey of 2012 and purpose was to investigate the effects of menopause on the metabolic syndrome(MetS) in Korean women. In raw data, total 2,746 women aged ${\geq}19$ years and provided the correct data about menstruation and menopause were analysed. The results were as follows: First, components of MetS were significantly different according to menopausal status. Second, the prevalence of MetS was 13.2% in premenopausal women and 42.7% in postmenopausal women. Third, the Odds ratio of postmenopausal women was 4.88(95% CI=3.888-6.126) compared with premenopausal women for MetS. As 5 years from 40 years increased, the Odds ratios of postmenopausal women were 3.15(95% Confidence Interval=1.862-5.331), 4.159(2.558-6.761), 5.971(3.955-9.016), 9.52(6.591-13.749) compared with premenopausal women for MetS, respectively. Based on the results, the intervention should be developed and provided for preventing and managing the MetS in postmenopausal women.

Effects of Menopause Symptoms on Stress and Quality of Life Satisfaction (폐경증상이 스트레스와 삶의 질 만족도에 미치는 영향)

  • Lee, Mi-Na
    • The Journal of the Korea Contents Association
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    • v.20 no.12
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    • pp.198-205
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    • 2020
  • This study was conducted to explore the relationship between stress and quality of life experienced by middle-aged women according to menopause and to provide basic data for improving the quality of life and health of middle-aged women. The data collection period was from September 02, 2019 to November 29, 2019, and a total of 400 questionnaires were distributed and 362 copies were used, excluding unscrupulous responses. As a result of the study, it was found that the more severe the menopause symptoms, the higher the effect on physical stress and psychological stress(p<.001). In addition, in terms of quality of life satisfaction, the more severe the menopause symptoms were, the higher the satisfaction was with physical and psychological health, but it could be seen that it did not have a significant effect on the satisfaction of social and environmental relationships. In future studies, further studies require a detailed observation of various menopause conditions and symptoms, and a multi-view approach. In addition, education and intervention programs should be activated to alleviate the symptoms of menopause and to receive relevant information.

Comparison of metabolic syndrome indicators and nutrient intakes in postmenopausal women : from the Korean National Health and Nutrition Examination Survey, 2010~2012 (폐경 후 여성의 대사증후군 지표와 영양소 섭취에 대한 비교 융합연구 : 2010~2012 국민건강영양조사자료 이용)

  • Hwang, Hyo-Jeong;Choi, Yean Jung
    • Journal of the Korea Convergence Society
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    • v.10 no.9
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    • pp.99-110
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    • 2019
  • The purpose of this study was to investigate the comparison between metabolic syndrome indicators and nutrient intakes in Korean menopausal women from the Korean National Health and Nutrition Examinations Survey data (2010~2012). Menopausal Status were classified into premature menopause(n=214) and natural menopause(n=2,546). Among the nutrient groups, retinol intake was a significant factor in natural menopausal women according to BMI levels and riboflavin intake was another significant factor in premature menopausal women according to fasting glucose levels. The results suggested that micronutrient including retinol, riboflavin, fiber and calcium were significantly associated with metabolic syndrome risk in Korean postmenopausal women. Further research is required for elucidating the association between nutrient intakes and incidence of metabolic syndrome in postmenopausal women within a large population in prospective studies.

Relation between Health Status and Intake of Soy Isoflavone among Adult Women in Seoul (서울 거주 성인 여성의 대두 이소플라본 섭취와 건강과의 관련성)

  • Lee, Min-June;Sohn, Chun-Young;Park, Ok-Jin
    • Journal of the East Asian Society of Dietary Life
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    • v.20 no.2
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    • pp.218-230
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    • 2010
  • This study was conducted to survey isoflavone intake among adult women in menopause with diseases such as metabolic syndrome and osteoporosis and to analyze the relationship between each of these chronic diseases followed by isoflavone intake and the related health risk index. The average age of the subjects was 49.97 years old, while that of the pre-menopausal subjects was 45.14 years, and the post-menopausal subjects was 55.99 years. The average body mass index (BMI), waist-hip circumference, body fat percentage, blood pressure, blood sugar and blood lipid content of the post-menopausal subjects were higher in significant difference than those of the pre-menopausal subjects. The bone density of the hip and spine in post-menopausal subjects was lower in significant difference than that of the pre-menopausal subjects. After menopause, the subjects had a lower ratio of individuals at risk of anemia when compared with the subjects before menopause, but had higher health risk ratio related to each type of chronic disease, including obesity, hypertension, high cholesterol and osteoporosis than the subjects before menopause. The intake frequency of each soybean food was similar among subjects before/after menopause. The most common soybean based foods consumed by the subjects were soybean, soybean curd and soybean paste. The average daily intake level of isoflavone among subjects before menopause was 25.48 mg, while that of subjects after menopause was 32.25 mg. Evaluation of the distribution of the isoflavone level revealed that the pre-menopausal subjects consumed 3.29~78.36 mg and the post-menopausal subjects consumed 3.18~116.59 mg. The intake level by each individual varied greatly. The pre-menopausal subjects had a low BMI index and systolic blood pressure as much as their isoflavone intake level was high. Additionally, the post-menopausal subjects had a low menarche age and high menopause age when their isoflavone intake level was high, the BMI index and waist-hip circumference ratio was highest among individuals with lowest isoflavone intake level. This study showed that there was a possible relationship between soybean isoflavone intake and health problems such as obesity, high cholesterol, and osteoporosis in women after menopause with diseases such as metabolic syndrome and osteoporosis, even if this relationship was not great.