• Title/Summary/Keyword: A-KRS

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A-KRS GoldSim Model Verification: A Comparison Study of Performance Assessment Model (KAERI A-KRS 골드심 성능평가 모델 비교 검증 연구)

  • Lee, Youn-Myoung;Jeong, Jongtae
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.11 no.2
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    • pp.103-114
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    • 2013
  • The Korea Atomic Energy Research Institute has developed a performance assessment model implementing the A-KRS concept, which was constructed with the GoldSim. In the A-KRS concept, spent nuclear fuel produced from pressurized-water-reactor operations would be pyroprocessed to reduce waste volume and radioactivity. The wastes to be disposed of in a geologic repository are comprised of metal and ceramic waste forms. In this study, results of simulations conducted to establish credibility and build confidence for the A-KRS model are presented. Specifically, release rates and breakthrough times simulated using the A-KRS model were compared to corresponding results from the U.S. NRC SOAR model. In addition, the A-KRS model results were compared to published release rates from the SKB repository performance assessment. This comparison of the A-KRS model results to other independent performance assessments is expected to form part of a suite of model verification and validation activities to provide confidence that the A-KRS model has been implemented appropriately.

Lysyl-tRNA Synthetase Inhibits Various Shear Stress-stimulated Signaling Pathways in Endothelial Cells

  • Park, Heon-Yong
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2008.04a
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    • pp.103-115
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    • 2008
  • Hemodynamic shear stress, the dragging force generated by blood flow, is known as an anti-atherogenic factor. We tested whether lysyl-tRNA synthetase (KRS) will be utilized as an agent controlling shear-sensing systems. KRS was previously known to be secreted as a pro-inflammatory agent. Here we found that KRS inhibited various shear-stimulated signaling pathways. We further found that KRS binds to detergent-resistant membrane (DRM), indicating that KRS binding molecules exist in DRM, specialized regions of the plasma membrane. DRM plays important roles in a variety of cellular processes and consists of gangliosides, signaling molecules and cytoskeletons. We then determined that KRS was colocalized with integrins ${\alpha}4$, ${\alpha}5$ and $av{\beta}3$. In addition, KRS was shown to be associated with sialic acid, existing at the end of gangliosides. Interestingly, the adherent effect of KRS was inhibited by pretreatment with sialic acid. Moreover, treatment of endothelial cells with neuraminidase appeared to inhibit both the KRS adhesion to endothelial cells and shear-stimulated signaling. In conclusion, KRS is likely to be utilized as a vascular regulator.

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The Conformity of Korean Railway Standards with International Standards : Automatic Coupler (한국철도표준규격 국제규격 부합화 : 자동연결기)

  • Kim, Jeong-Guk;Lee, Chang-Young;Seo, Jung-Won;Kwon, Sung-Tae
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.213-218
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    • 2009
  • The Korean railway standards (KRS), formerly managed by Korea Railroad (Korail), have been managed by the Korean Ministry of Land, Transport and Maritime Affairs (ML TM). According to Korean railway safety law and its ordinances, which were established for the guarantee of railway safety, the management of KRS including enactment and revision of technical standards for railway vehicle and components, was committed to Korea Railroad Research Institute (KRRI). Currently, a total of 195 standards has been managed from the various railway applications including track, electrical, and vehicle areas. Moreover, according to the guideline on the management of KRS, the conformity of KRS with international standards is encouraged for the enlargement of international trade. In this investigation, a brief management activity of KRS and the recent activities on conformity of KRS with AAR standards on automatic coupler will be introduced.

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Antifungal and Plant Growth Promotion Activities of Recombinant Defensin Proteins from the Seed of Korean Radish (Raphanus sativus L.)

  • Hwang, Cher-Won
    • Korean Journal of Environmental Agriculture
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    • v.28 no.4
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    • pp.435-441
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    • 2009
  • In the present study, we analyzed the defensin protein deduced from Korean radish (Raphanus sativus L.) seeds.To express the genes in E. coli, we constructed a recombinant expression vector with a defensin gene, named rKRs-AFP gene isolated from Korean radish seeds. Over expressed rKRs-AFP proteins was separated by SDS-PAGE to determine the purity, and protein concentration was determined by the Bradford method. Antifungal activity was assessed by disk assay method against the tested fungi. As a result, when 500 mL of cell culture were disrupted by sonicator, 32.5 mg total proteins were obtained. The purified protein showed a single band on SDS-PAGE with estimated molecular weight about 6 KDa, consistent with the molecular mass calculated from the deduced amino acid sequence. The purified rKRs-AFP protein showed remarkable antifungal activities against several fungi including Aspergillus niger, Botrytis cinerea causing the gray mold disease, and Candida albicans. In field tests using the purified rKRs-AFP protein, the protein showed the reducing activity of disease spot and the mitigating effect of spreading of disease like agrichemicals. The immuno-assay of rKRs-AFP protein showed that the purified protein entirely accumulated at B. cinerea cytoplasm through the hyphal septa shown by fluorescence imaging. There was no fluorescence inside the cell, when the hypha was incubated without the protein. These all results indicate that the recombinant rKRs-AFP proteins can be utilized as a potential antifungal drug to control harmful plant fungal pathogens.

SAT#1 (Preliminary Integration) Test Results of KASS System

  • Jeong, Hwanho;Jang, HyunJin;Kim, Koontack;Lee, Jaeeun;Lee, ByungSeok
    • Journal of Positioning, Navigation, and Timing
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    • v.10 no.2
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    • pp.145-151
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    • 2021
  • According to the Korea Augmentation Satellite System (KASS) system milestone, Site Acceptance Test (SAT) has three steps test until the end of the project. SAT#1 is the first time of SAT steps and verify the KASS Reference Station (KRS) and Sub System (S/S) for the monitoring and controllable. After the equipment and software were installed at the Mission Control Center (MCC) with Central Monitoring and Control Simulator (CMS) for the SAT#1, the 1:1 test was progressed when the KRS and S/S are ready to test. SAT#1 has a 10 steps test case and it was progressed each KRS sites. The test was finished throughout the real-time monitoring and the data collection including the data analysis all of the 7 KRS sites. Finally SAT#1 was completed on December 2020 with successfully.

Multipath Error Analysis and Scenario Generation for Verifying KRS Environment

  • Cho, Sunglyong;Choi, Heonho;Lee, Byungseok;Nam, Giwook
    • Journal of Positioning, Navigation, and Timing
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    • v.9 no.2
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    • pp.71-77
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    • 2020
  • KRS which is subsystem of Korea Augmentation Satellite System (KASS) performs a role of collecting and monitoring GPS signals. In order to generate the accurate correction message, the site which meets the requirements should be selected and verification to meet each requirement should be accompanied. When the sites are selected, the environmental considerations are EMI, clear horizon (CH) and multipath. Of these, EMI and CH can be checked for satisfaction by instrumentation, but multipath error is difficult to predict. Therefore, multipath error analysis for the installation position of actual antenna at each KRS site should be preceded, and multipath scenario should be generated for each location to analyze the effects of the resulting system performance. In this paper, based on satellite signals collected from each KRS sites, the method for analyzing multipath error in each KRS sites is described, and the multipath error is analyzed. Also to perform an analysis of the effects on system performance due to multipath error, multipath error modeling is performed for the generation of simulation scenarios.

Potential repository domain for A-KRS at KURT facility site (KURT 부지 조건에서 A-KRS 입지 영역 도출)

  • Kim, Kyung-Su;Park, Kyung-Woo;Kim, Geon-Young;Choi, Heui-Joo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.10 no.3
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    • pp.151-159
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    • 2012
  • The potential repository domains for A-KRS (Advanced Korean Reference Disposal System for High Level Wastes) in geological characteristics of KURT (KAERI Underground Research Tunnel) facility site were proposed to develop a repository system design and to perform the safety assessment. The host rock of KURT facility site is one of major Mesozoic plutonic rocks in Korean peninsula, two-mica granite, which was influenced by hydrothermal alteration. The topographical features control the flow lines of surface and groundwater toward south-easterly and all waters discharge to Geum River. Fracture zones distributed in study site are classified into order 2 magnitude and their dominant orientations are N-S and E-W strike. From the geological features and fracture zones, the potential repository domains for A-KRS were determined spatially based on the following conditions: (1) fracture zone must not cross the repository; and (2) the repository must stay away from the fracture zones greater than 50 m. The western region of the fracture zones in the N-S direction with a depth below 200 m from the surface was sufficient for A-KRS repository. Because most of the fracture zones in N-S direction were inclined toward the east, we expected to find a homogeneous rock mass in the western region rather than in the eastern region. The lower left domain of potential domains has more suitable geological and hydrogeological conditions for A-KRS repository.

Scoping Calculations on Criticality and Shielding of the Improved KAERI Reference Disposal System for SNFs (KRS+)

  • Kim, In-Young;Cho, Dong-Keun;Lee, Jongyoul;Choi, Heui-Joo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.18 no.spc
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    • pp.37-50
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    • 2020
  • In this paper, an overview of the scoping calculation results is provided with respect to criticality and radiation shielding of two KBS-3V type PWR SNF disposal systems and one NWMO-type CANDU SNF disposal system of the improved KAERI reference disposal system for SNFs (KRS+). The results confirmed that the calculated effective multiplication factors (keff) of each disposal system comply with the design criteria (< 0.95). Based on a sensitivity study, the bounding conditions for criticality assumed a flooded container, actinide-only fuel composition, and a decay time of tens of thousands of years. The necessity of mixed loading for some PWR SNFs with high enrichment and low discharge burnup was identified from the evaluated preliminary possible loading area. Furthermore, the absorbed dose rate in the bentonite region was confirmed to be considerably lower than the design criterion (< 1 Gy·hr-1). Entire PWR SNFs with various enrichment and discharge burnup can be deposited in the KRS+ system without any shielding issues. The container thickness applied to the current KRS+ design was clarified as sufficient considering the minimum thickness of the container to satisfy the shielding criterion. In conclusion, the current KRS+ design is suitable in terms of nuclear criticality and radiation shielding.

A Deterministic Safety Assessment of a Pyro-processed Waste Repository (A-KRS 처분 시스템 결정론적 안전성 평가)

  • Lee, Youn-Myoung;Jeong, Jongtae;Choi, Jongwon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.10 no.3
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    • pp.171-188
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    • 2012
  • A GoldSim template program for a safety assessment of a hybrid-typed repository system, called "A-KRS," in which two kinds of pyro-processed radioactive wastes, low-level metal wastes and ceramic high-level wastes that arise from the pyro-processing of PWR nuclear spent fuels are disposed of, has been developed. This program is ready both for a deterministic and probabilistic total system performance assessment which is able to evaluate nuclide release from the repository and farther transport into the geosphere and biosphere under various normal, disruptive natural and manmade events, and scenarios. The A-KRS has been deterministically assessed with 5 various normal and abnormal scenarios associated with nuclide release and transport in and around the repository. Dose exposure rates to the farming exposure group have been evaluated in accordance with all the scenarios and then compared among other.

Geodetic Survey Campaigns and Maintenance Plan for KASS Reference Station Antenna Coordinates

  • Hwanho, Jeong;Hyunjin, Jang;Youngsun, Yun;ByungSeok, Lee
    • Journal of Positioning, Navigation, and Timing
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    • v.12 no.1
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    • pp.83-89
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    • 2023
  • The Korea Augmentation Satellite System (KASS) system is a Satellite Based Augmentation System (SBAS) under development to provide APV-I SBAS service in the Republic of Korea. The KASS ground segment generates correction and integrity information for GPS measurements of KASS users using the accurate positions of KASS Reference Station (KRS) antenna phase centers. For this reason, the accuracy of KRS reference points through geodetic survey campaigns is one of the important factors for providing the KASS service in compliance with the required navigation performance. In order to obtain accurate positions, two geodetic survey campaigns were performed at several reference points, such as Mark, Center of Mast at Ground Level (CMGL), and Center of Hole in Top Plate (CHTP), of each KRS site using three different survey methods, the Virtual Reference Station (VRS), Flächen Korrektur Parameter (FKP), and raw data post-processing methods. By comparing and analyzing the results, the computed coordinates of the reference points were verified and Antenna Phase Center (APC) positions were calculated using KRS Antenna Reference Point (ARP) data, and the first KASS Site Acceptance Test (SAT#1) was performed successfully using the verified APC coordinates. After the first site survey activities, the KASS operators should maintain the coordinates with the required performance such that the overall KASS navigation performance commitment is guaranteed during the lifetime of 15 years. Therefore, the maintenance plan for the KRS antenna coordinates should be developed before the commissioning of KASS operation planned after 2023. Therefore, this paper presents a geodetic survey method selected for the maintenance activities and provides the rationale for using this method.