• Journal of the Korea Society of Computer and Information
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• v.8 no.4
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• pp.28-34
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• 2003

ASN.1 is the most fundamental technology in network management. The develoment of ASN.1 environment requires three steps : compiler work to parse ASN.1 languages, updating database with the parsing results, and pretty-printing work for data in the database. This paper presents the design and implementation of the translator which automatically translates the specification of ASN.1 to the object-oriented language C++. This system provides a total environment including for various graphic user interface, DB interface, browser to develop ASN.1 for development environment of ASN.1 For the implementation, Objectivity DB is used for database, flex and yacc for compiling, and Tcl/Tk for user interface.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.33A no.3
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• pp.28-37
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• 1996

Syntax notation one (ASN.1) defined by ITU-T and ISO, is a formal abstrct specification language which has been widely used in international standards specifiation to inteconnect distributed open systems. It si necessary to have well defined encoder/decoder modules which taranslate ASN.1 datum to BER octets stream to interconnect distributed open systems. In this paper, we designed and implemented a new ASN.1-to-C compiler, called HYASNC (hanyang ASN.1-to-C), which atutomatically translates and ASN.1-to-C compiler, called HYASNC (hanyang ASN.1-to-C), which automatically translates an ASN.1 specification into C-language BER encoders and decoders with simple and neat I/F for the defined ASN.1 data types, and enhanced BER (basic encoding rules)encoding/decoding libraries, called HY(hanyang)BER library, and useful utility functions. And this paper discusses HYASNC compiler, HY BER runtime library's design and implementation principles, and also evaluates the perfomrance of HY BER library and the interoperability with other ASN.1 compilers.

• The KIPS Transactions:PartC
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• v.11C no.4
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• pp.463-470
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• 2004

ASN.1/GDMO is the management object used in network management of TMN(Telecommunication Management of Network). However, ASN.1/GDMO is not directly used for managing the network, but translated Into a language with object-oriented paradigm. Therefore we need a development environment for handling ASN.1/GDMO. In this paper we present an integrated development environment(IDE) which consists of an editor and a browser. A user manages ASN.1/GDMO elements with GUI. The IDE is implemented with FLEX and BYACC in UNIX. And Objectivity DB is used as the DB and Tcl/Tk is used for developing GUI. This paper shows how the integrated environment of ASN.1 and GDMO works, and that it enables to manage efficiently the network.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3299-3303
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• 2012

Objective: To investigate the association between xeroderma pigmentosum group D (XPD) Asp312Asn polymorphism and esophageal cancer (EC) susceptibility by meta-analysis. Methods: We searched PubMed up to April 9th, 2012, to identify relevant papers, and 8 published case-control studies including 2165 EC patients and 3141 healthy controls were yielded. Odds ratios (ORs) with relevant 95% confidence intervals (CIs) were applied to assess the association between XPD Asp312Asn polymorphism and EC susceptibility with the Comprehensive Meta-Analysis software, version 2.2. Results: Overall, the meta-analysis results suggested the XPD Asp312Asn polymorphism to be significantly associated with EC susceptibility [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.20, 95%CI=1.05-1.36, p=0.01; and Asp/Asn vs. Asp/Asp: OR=1.15, 95%CI =1.01-1.31, p=0.04]. In the subgroup analysis by ethnicity and cancer type, significantly associations were found for Caucasian populations [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.26, 95%CI =1.08-1.47, p<0.001; Asp/Asn vs. Asp/Asp: OR=1.19, 95%CI =1.02-1.40, p=0.03] and esophageal squamous cell carcinoma [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.19, 95%CI=1.01-1.41, p=0.04]. There was no heterogeneity and no publication bias existed. Conclusions: This meta-analysis shows that the XPD Asp312Asn polymorphism may be a risk factor for developing EC, especially for Caucasian populations and esophageal squamous cell carcinoma.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.33A no.6
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• pp.1-10
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• 1996

Protocol specifications and service definitions for distributed open system applications are defined using ASN.1. Therefore, to implement an open system application likes MHS, it is necessary to have well defined encoding/decoding modules which translate ASN.1 protocol specifications into their transfer syntaxes. However, that work is usually tedius, time consuming, and error prone. In this paper, we designed and implemented a new ASN.1 tool set which includes a new ASN.1 run-time library, called HY BER/DER, and an enhanced ASN.1-to-C compiler, called HYASNC$^{+}$. HYASNC$^{+}$ automatically generates C language encoder/decoder stub files and heder files for basic ASN.1 types and subtypes defiend in X.208 recommandation, and all X400 MHS system macro definitions. And, we evaluated the performance of HYASNC$^{+}$ compiler and HY BER/DER run-tiem library, and tested the interoperability of ASN.1 run-time library.

• Journal of Acupuncture Research
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• v.38 no.2
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• pp.140-145
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• 2021

Background: Aconitum sinomontanum Nakai (ASN) has been reported to have analgesic effects. In this study an animal model of pharmacopuncture using ASN (100-500 mg/kg) was examined. Methods: Sprague-Dawley (SD) rats (n = 40) were randomly assigned to ASN-Low (1 mg/mL, 1.8 mL, ASN-L), ASN-Intermediate (5 mg/mL, 1.8 mL, ASN-M), ASN-High (10 mg/mL, 1.8 mL, ASN-H), negative control (0.2 mL normal saline), and positive control (0.2 mL 0.5% lidocaine) groups. All experiments were administered to the rats' left hind leg. The analgesic response was assessed by monitoring the physical (hot plate, and von Frey test) and chemical (formalin) responses to pain. Results: All ASN pharmacopuncture groups demonstrated significant differences in pain response to the hot plate test, von Frey test, and formalin test, compared to the control group (p < 0.05). The response of the ASN-M group and ASN-H groups to the hot plate, the formalin, and the von Frey tests were significantly different, compared to the lidocaine group (p < 0.05). Conclusion: ASN pharmacopuncture had a significant analgesic effect on SD rats in response to physical and chemical models of pain.

• Journal of Software Engineering Society
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• v.25 no.2
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• pp.35-47
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• 2012

Variable Message Format(VMF) is a communications protocol that allows computers to exchange tactical military information over low-data-rate bearers. VMF is designed to define message length and structure variably in order to allow the user to transmit only the relevant information by using indicators. However, flexibility of messages makes it difficult to analyze messages structure and figure out meanings. Furthermore, whenever messages are added or modified, message processing software should be updated and distributed to systems. In this paper, we propose a systematic approach to defining VMF messages that uses the international standard notation ASN.1. By describing VMF messages in ASN.1, protocol architects can deal with VMF messages accurately and conveniently, and use various ASN.1 tool. This paper develops ASN.1 description templates for VMF message segments, and presents an approach to describing VMF messages in ASN.1 by combining the templates.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3821-3824
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• 2012

Aim: SNPs of ERCC1 and ERCC2 genes have been found to be associated with response to platinum therapy in different clinical settings. In the current study, we investigated the relationship of SNPs in ERCC1 and ERCC2 to cisplain response and survival in osteosarcoma patients. Methods: 267 consecutive patients diagnosed with osteosarcoma between January 2003 to January 2005 were followed up until the end of January 2010. ERCC1 Asn118Asn, ERCC1 Gln504Lys, ERCC2 Asp312Asn and ERCC2 Lys751Gln polymorphisms were detected based upon the Sequenom MassARRAY platform.Results: For ERCC1 Asn118Asn, the variant genotype T/T was strongly significantly associated with a higher event free survival when compared with the wild-type C/C, with an adjusted OR (95% CI) of 0.39 (0.14-0.95). ERCC2 751 A/A genotype showed increased event free survival of osteosarcoma (HR=0.44; 95%CI=0.10-0.87). However, we did not find significant association of ERCC1 Gln504Lys and ERCC2 Asp312Asn polymorphisms with prognosis of osteosarcoma. Conclusions: We first report associations of four SNPs, ERCC1 Asn118Asn, ERCC1 Gln504Lys, ERCC2 Asp312Asn and ERCC2 Lys751Gln, with risk of death from osteosarcoma in a Chinese population, indicating ERCC1 118T/T and ERCC2 A/A may be used as surrogate markers for clinical outcome of osteosarcoma treatmetn with cisplain.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.231-236
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• 2013

Background: Published data regarding the association between xeroderma pigmentosum group D (XPD) Lys751Gln and Asp312Asn polymorphisms and gastric cancer susceptibility havew been inconclusive. This meta-analysis was therefore performed toobtain a more precise estimation of any relationship. Materials and Methods: A comprehensive literature search was conducted to identify all case-control studies of Lys751Gln and Asp312Asn polymorphisms and susceptibility to gastric cancer. Summary odds ratios (ORs) and its 95% confidence intervals (95% CIs) were calculated using a random-effects model with the software STATA (version10.0). Results: A total of 12 case-control studies including 3,147 cases and 4,736 controls were included. Overall, no significant associations were found in some models (for Lys751Gln: Lys/Gln vs Lys/Lys: OR=1.144, 95% CI=0.851-1.541, Gln/Gln vs Lys/Lys: OR=1.215, 95% CI = 0.740-1.955, dominant model: OR=1.137, 95% CI=0.818-1.582; recessive model: OR=1.123, 95% CI=0.765-1.650; for Asp312Asn: Asp/Asn vs Asp/Asp: OR=1.180, 95% CI=0.646-2.154, dominant model: OR=1.380, 95% CI = 0.812-2.346), but significantly elevated susceptibility was found for Asp312Asn polymorphism in some models (Asn/Asn vs Asp/Asp: OR=2.045, 95% CI=1.254-3.335, recessive model: OR=1.805, 95% CI =1.219-2.672), for the additive model, the XPD Lys751Gln and Asp312Asn polymorphisms were not significantly associated with gastric cancer susceptibility. In stratified analyses, significantly elevated susceptibility was found for some models in the Chinese population. Conclusion: This meta-analysis suggested the XPD Asp312Asn polymorphism might be a potential biomarker of gastric cancer susceptibility in overall population, while both XPD Lys751Gln and Asp312Asn polymorphisms might be risk factors of gastric cancer susceptibility in Chinese.

• Mycobiology
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• v.42 no.4
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• pp.322-330
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• 2014

The aim of this study was to identify and characterize new Flammulina velutipes laccases from its whole-genome sequence. Of the 15 putative laccase genes detected in the F. velutipes genome, four new laccase genes (fvLac-1, fvLac-2, fvLac3, and fvLac-4) were found to contain four complete copper-binding regions (ten histidine residues and one cysteine residue) and four cysteine residues involved in forming disulfide bridges, fvLac-1, fvLac-2, fvLac3, and fvLac-4, encoding proteins consisting of 516, 518, 515, and 533 amino acid residues, respectively. Potential N-glycosylation sites (Asn-Xaa-Ser/Thr) were identified in the cDNA sequence of fvLac-1 (Asn-454), fvLac-2 (Asn-437 and Asn-455), fvLac-3 (Asn-111 and Asn-237), and fvLac4 (Asn-402 and Asn-457). In addition, the first 19~20 amino acid residues of these proteins were predicted to comprise signal peptides. Laccase activity assays and reverse transcription polymerase chain reaction analyses clearly reveal that $CuSO_4$ affects the induction and the transcription level of these laccase genes.