• Title/Summary/Keyword: Aggregation state

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Synthesis, application of thermally stable red dyes for LCD colorfilter ; Influence of dye structures on the aggregation property in the film state

  • Sakong, Chun;Kim, Young-Do;Kim, Jae-Pil
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.847-850
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    • 2008
  • Three thermally stable red dyes of azo, quinacridone and perylene derivatives were synthesized and dye-based color filters were manufactured for liquid crystal display. Aggregation behavior of the dyes and their spectral property in film state were investigated by concentration dependent spectroscopy and field emission scanning electron microscopy (FE-SEM). These dyes have remarkable difference on their aggregation behavior in film state. Such difference of aggregation behavior affects the spectral property of the film, and it can cause decreasing the transmittance of dye-based color filters.

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Syntheses and Characterisitics of New Photochromic Spiroxazine Dyes (새로운 광변색성 Spiroxazine색소의 합성과 특성)

  • 김성훈
    • Journal of the Korean Graphic Arts Communication Society
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    • v.12 no.1
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    • pp.159-168
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    • 1994
  • The Aggregation State of thin vapor deposite Film made by Cyanine Dye were changed into Monomeric molecular state(M) and Dimeric Aggregation(D) at the acidic treatment, into reversible H-Aggregation (H) at alkalic gas or heat treatment. Photo-electric properties were higher H than D and M, this stats were effective in enhancing Photoelectric-conversion characteristic. Substitute group of Meso-Position being stronger electronic Donors, Electronic density is higher and Electric conductivity is enhanced, we confirmed Oscillator Strength calculated by PPP-Molecular Orbital Calculation and Absorption Spectra at solvent stats were agreed good.

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A Study on Coherency Aggregation Method Using Relation Index of State Variables in the Power System (상태변수들의 관계지수를 이용한 전력시스템 동적 축약기법 연구)

  • Lee, Byung-Ha;Baek, Jung-Myoung
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.8
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    • pp.1367-1372
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    • 2007
  • The modem large electric power system has made power system analysis much more complex and difficult. For effective analysis of the power system, model reduction and aggregation is required. In this paper, a new relation index to identify the coherency among the generators is presented and also a new aggregation method is presented to aggregate the coherent generators in the large scale power system while matching the power flow. In order to demonstrate the effects of this aggregation method, it is applied to the IEEE 39 bus test power system and to the 2006 summer power system of Korea Electric Power Corporation, and the simulation results are compared with those of the original system.

NMR-based structural characterization of transthyretin in its aggregation-prone state

  • Kim, Bokyung;Kim, Jin Hae
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.3
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    • pp.91-95
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    • 2020
  • Transthyretin (TTR) is an abundant protein in blood plasma and cerebrospinal fluid (CSF), working as a homo-tetrameric complex to transport thyroxine (T4) and a holo-retinol binding protein. TTR is well-known for its amyloidogenic property; several types of systemic amyloidosis diseases are caused by aggregation of either wild-type TTR or its variants, for which more than 100 mutations were reported to increase the amyloidogenicity of TTR. The rate-limiting step of TTR aggregation is the dissociation of a monomeric subunit from a tetrameric complex. A wide range of biochemical and biophysical techniques have been employed to elucidate the TTR aggregation processes, among which nuclear magnetic resonance (NMR) spectroscopy contributed much to characterize the structural and functional features of TTR during its aggregation processes. The present review focuses on discussing the recent advances of our understanding to the amyloidosis mechanism of TTR and to the structural features of its monomeric aggregation-prone state in solution. We expect that the present review provides novel insights to appreciate the molecular basis of TTR amyloidosis and to develop novel therapeutic strategies to treat diverse TTR-related diseases.

The Effect of Polyethylene Oxide on the Aggregation State and Toxicity of Amphotericin B (폴리에틸렌 옥사이드가 암포테리신-B의 응집 특성 및 독성에 미치는 영향)

  • Yu, Bong-G.
    • Journal of Pharmaceutical Investigation
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    • v.31 no.1
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    • pp.7-12
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    • 2001
  • Amphotericin B (AmB) is a drug of choice for the treatment of systemic fungal diseases, but its use is considerably limited due to a high incidence of toxicity, particularly nephrotoxicity. It has been demonstrated that the toxicity of AmB is caused by self-aggregated species of the drug and that unaggregated (monomeric) drug is nontoxic but still expresses antifungal activity. Poly (ethylene oxide) (PEO) is a water-soluble polymer, which may impact the aggregation state of AmB. We have studied the aggregation state of AmB as a function of PEO molecular weight and concentration. At 3,000 and 8,000 g/mole, there was minimal or no change of critical aggregation concentration (CAC) of AmB regardless of the concentration of polymer. By contrast at 20,000 g/mole, the CAC of AmB strikingly increased to 24.3 and $37.5\;{\mu}M$ at 5.0% and 10 % w/v of polymer, respectively. The critical overlap concentration (COC) of PEO 20,000 g/mole was 5.5%. It appears that an interaction between monomeric AmB and polymer coil increases above the COC, competing with self-aggregation of the drug. Accordingly, the degree of aggregation of AmB stayed low and the toxicity became less. There was no such effect at 3,000 and 8,000 g/mole of PEO, owing perhaps to small dimensions in comparison to AmB. Based upon these findings, less toxic AmB formulation may be developed by a pharmaceutical technique such as solid dispersion system containing both AmB and PEO 20,000 g/mole.

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Spectroscopic Evidence for Aggregation of Stilbene Derivatives in Solution

  • Aguiar, M.;Akcelrud, L.;Pinto, M.R.;Atvars, T.D.Z.;Karasz, F.E.;Saltiel, Jack
    • Journal of Photoscience
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    • v.10 no.1
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    • pp.149-155
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    • 2003
  • The absorption, fluorescence and fluorescence-excitation spectra of concentrated toluene solutions of selected para substituted trans-stilbene derivatives provide strong evidence for aggregation. A red-shifted fluorescence spectrum peaking at 420 nm gains in intensity as the stilbene concentration is increased. The excitation spectrum of this new emission is well to the red of the normal stilbene absorption spectrum, consistent with the appearance of a red shifted shoulder in the UV spectrum. Formation of a fluorescent ground state dimer (or higher aggregate) is proposed to account for these observations. The presence of polar substituents is crucial to the formation of this ground state complex.

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Numerical Simulation far the Non-Spherical Aggregation of Charged Particles (하전 입자의 비구형 응집 성장에 대한 수치적 연구)

  • Park, Hyeong-Ho;Kim, Sang-Su;Jang, Hyeok-Sang
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.26 no.2
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    • pp.227-237
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    • 2002
  • A numerical technique for simulating the aggregation of charged particles was presented with a Brownian dynamic simulation in the free molecular regime. The Langevin equation was used for tracking each particle making up an aggregate. A periodic boundary condition was used for calculation of the aggregation process in each cell with 500 primary particles of 16 nm in diameter. We considered the thermal force and the electrostatic force for the calculation of the particle motion. The electrostatic force on a particle in the simulation cell was considered as a sum of electrostatic forces from other particles in the original cell and its replicate cells. We assumed that the electric charges accumulated on an aggregate were located on its center of mass, and aggregates were only charged with pre-charged primary particles. The morphological shape of aggregates was described in terms of the fractal dimension. In the simulation, the fractal dimension for the uncharged aggregate was D$\_$f/ = 1.761. The fractal dimension changed slightly for the various amounts of bipolar charge. However, in case of unipolar charge, the fractal dimension decreased from 1.641 to 1.537 with the increase of the average number of charges on the particles from 0.2 to 0.3 in initial states. In the bipolar charge state, the average sizes of aggregates were larger than that of the uncharged state in the early and middle stages of aggregation process, but were almost the same as the case of the uncharged state in the final stage. On the other hand, in the unipolar charge state, the average size of aggregates and the dispersion of particle volume decreased with the increasing of the charge quantities.

An Improvement Delay Efficient Scheduling Scheme for Data Aggregation in Duty-Cycle MWSNs (듀티 사이클 MWSN 에서 데이터 집계를위한 개선 지연 효율적인 스케줄링 체계)

  • Vo, Van-Vi;Kim, Moonseong;Choo, Hyunseung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2020.11a
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    • pp.175-177
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    • 2020
  • In multi-channel wireless sensor networks, optimizing data aggregation delay without any channels and timeslots conflicts has been concerned these days. The aggregation delay can be reduced by using different aggregation tree construction methods or scheduling in different methods in bottom-up or top-down manners. In this paper, we propose a new way of constructing aggregation tree purposing to decrease the total aggregation delay. The result shows that our proposed scheme can improve up to 64% comparing with state-of-the-art schemes.

Control and Aggregation (I)

  • Han, Sung-Shin
    • Journal of the Korean Statistical Society
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    • v.8 no.2
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    • pp.139-163
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    • 1979
  • Utilization of the aggregation concept applied in economics has been a traditional way of describing the state of an economic system and of predicting the future economic conditions. In addition, certain aggregate variables have also played a crucial role as indicators of the business cycle. Quick examples would be the price index, the productivity changes, the industrial production index, GNP, and so on. The methods of aggregation could be either simple summations, like GNP, or sophisticated weighted average, like the price index.

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Interaction of Indigo Carmine with Cetyltrimethylammonium Bromide and Application to Determination of Cationic Surfactant in Wastewater

  • Wang, Hong-Yan;Gao, Hong-Wen;Zhao, Jian-Fu
    • Bulletin of the Korean Chemical Society
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    • v.24 no.10
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    • pp.1444-1448
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    • 2003
  • The microsurface adsorption - spectral correction (MSASC) technique has been applied to the interaction of indigo carmine (IC) with cetyltrimethylammonium bromide (CTAB). The aggregation of IC on CTAB obeys Langmuir isothermal adsorption. The results show that both the monomer complex $IC{\cdot}CTAB$ and the micellar complex $(IC{\cdot}CTAB)_{78}$ were formed. The binding constant of the monomer complex was calculated to be $K_{IC{\cdot}CTAB}$ = 2.20 ${\times}10^5L{\cdot}mol^{-1}$, and the molar absorptivity of the micellar complex was calculated to be ${\varepsilon}_{(IC{\cdot}CTAB)78}\;^{560nm}$ = 8.58 ${\times}10^5L{\cdot}mol^{-1}{\cdot}cm^{-1}$. The aggregation was applied to the determination of cationic surfactant in wastewater.