• Korean Journal of Pharmacognosy
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• v.45 no.3
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• pp.268-274
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• 2014

The aim of this study is to explore the potent phosphodiesterase 4 and 7 inhibitor from various herbal medicines for atopy treatment. In this study, 51 kinds of each herbal medicine, which were extracted with ethanol, was carried out the screening of PDE 4 and 7 inhibition using enzyme inhibitory assay. Of these, 8 species of herbal medicines, Rubus coreanus, Duchesnea chrysantha, Alisma orientale, Rehmannia glutinosa, Angelica dahurica, Thuja orientalis, Astragalus membranaceus and Perilla frutescens were screened as potential inhibitor against PDE 4 and 7. Among 8 species, Duchesnea chrysantha showed poteinial anti-atopic effect on DNCB-induced atopic model. Duchesnea chrysantha extract decreased serum IgE and histamine release significantly.

• The Korea Journal of Herbology
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• v.31 no.2
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• pp.47-62
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• 2016

Objectives : This study was aimed to analyze the correlation between the Herbology and contemporary research results, KCD and terms of Alismatis Rhizoma. The study will present information that can be used to find the direction of further researches and be applied to the education of Herbology.Methods : Papers were searched in Riss4U and PubMed, and categorized. Medicine or pharmacy articles about Alismatis Rhizoma were matched with the Herbology treatment and KCD. KCD-codes and terms were arranged by the Herbology treatment. The Degree of Herbology research (HDR) was calculated by numbers of papers, study method, citation rates.Results : There were 392 articles about Alismatis Rhizoma. Among these there were 141 medicine and pharmacy articles about Alismatis Rhizoma, and 51 articles were matched to the Herbology treatment. Studies about Phlegm-Fluid Retention and Dizziness, Edema and Distention and Fullness was more active than others. Analysis of other articles showed that studies about anti-cancer, anti-biotic effect, anti-diabetes mellitus, anti-oxidant effect, anti-inflammation, hepatoprotective effect were active, too. In HDR, Phlegm-Fluid Retention and Dizziness was scored by 181, Edema- Distention and Fullness by 173, Hyperlipidemia by 83, Dysuria 64, Heat strangury pain by 18, Diarrhea and decreased urine volum by 0.Conclusions : 141 articles about Alismatis Rhizoma were analyzed and 51 articles were matched to the Herbology treatment. Studies about Phlegm-Fluid Retention and Dizziness, Edema and Distention and Fullness were more active than others. And studies about anti-cancer, anti-biotic effect, anti-oxidant effect, anti-inflammation, Osteoporosis should be more studied and be more discussed among Herbology researchers.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.15 no.4
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• pp.61-80
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• 2012

This study is to offer the basic data for restoration and conservation of wetland ecosystem by surveying and analysing the flora distributed in the Binae marsh, Namhan River, Chungju-si. The flora in the Binae marsh were verified 204 taxa including 48 families, 152 genera, 179 species, 23 varieties and 2 forms. In flora, pteridophyta were 2 taxa including 1 family, 1 genus and 2 species, among angiospermae, dicotyledonae were 153 taxa including 37 families, 110 genera, 138 species, 13 varieties and 2 forms and monocotyledonae were 49 taxa including 10 families, 41 genera, 39 species and 10 varieties. In the result of classifying the life form of flora, megaphanerophytes (M), nanophanerophytes (N) and chamaiphytes (Ch) were each 9 taxa (4.4%), 37 taxa (18.1%) of hemicryptophytes (H), 19 taxa (9.3%) of geophytes (G), 97 taxa (47.6%) of therophytes (Th) and 24 taxa (11.8%) of hydrophytes (HH). The rare plant designated by Korea Forest Service was 1 taxa (Aristolochia contorta), and the endemic plant was 1 taxa (Salix koriyanagi) too. The specific plants by floristic region were 6 taxa. From among these, the species of degree I were 5 taxa including Salix chaenomeloides, Aristolochia contorta, Artemisia selengensis, Cirsium pendulum and Vallisneria natans, and degree III was 1 taxa including Alisma orientale. The naturalized plants were 45 taxa and the invasive alien plants were 3 taxa including Sicyos angulatus, Ambrosia artemisiifolia and Ambrosia trifida. The naturalized index (NI) was about 22.1%, 16.1% of urbanized index (UI) and 27.3% of disturbed index (DI). The extinct species by construction were 17 taxa including Persicaria sagittata, Typha orientalis, Zizania latifolia and so forth. The new-occured species were 14 taxa including Brassica juncea, Thlaspi arvense, Carduus crispus and so forth. The important species among the extinct species were Aristolochia contorta, Alisma orientale and Vallisneria natans.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.15-22
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• 2011

엘라스타제는 폐의 탄성 섬유를 파괴하여 폐기종과 폐고혈압을 유발하는 역할을 한다. 이에 본 연구는 택사(澤瀉) 약침액(藥鍼液)의 엘라스타제 억제효능과 항산화효능을 측정하여 폐기종과 폐고혈압 치료의 가능성을 확인하고자 실시 하였다. 방법 : 택사(澤瀉) 약침액(藥鍼液)의 엘라스타제에 대한 억제효능과 di(phenyl)-(2,4,6-trinitrophenyl) iminoazanium (DPPH) 및 nitric oxide (NO) 자유기 소거능을 측정하였다. 결과 : 택사(澤瀉) 약침액(藥鍼液)은 엘라스타제 활성을 통계적으로 유의하게 억제하였고, DPPH 및 NO 자유기 소거능이 있음이 통계적으로 유의하게 확인되었다. 결론 : 본 연구를 통해 택사(澤瀉) 약침액(藥鍼液)의 엘라스타제 억제효능과 항산화 효능이 확인되었다. 본 연구 결과를 근거로 시험관내 실험이외의 추가적인 연구를 통해 폐기종과 폐고혈압 치료제로서 택사(澤瀉) 약침액(藥鍼液)의 활용을 고려해 볼 수 있을 것으로 기대한다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.4
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• pp.958-962
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• 1999

Hydroxy methylglutaryl CoA(HMG CoA) reductase and acyl CoA:cholesterol acyltransferase(ACAT) are two important enzymes that are associated with regulation of cholesterol metabolism. The inhibitors of HMG CoA reductase and ACAT are very effective in lowering serum cholesterol in most animal species. In present study, various plant extracts with hot water were used to examine the inhibitory activities against HMG CoA reductase and ACAT that are involved in cholesterol biosynthesis and cholesterol esterification in tissues, respectively. The extracts of Fagophyrum rotundatum, Rosa multiflora, Rosa rugosa and Alisma orientalis exhibited significant inhibitory activities against the ACAT, 29%, 24%, 19%, and 18%, respectively. However the extracts of Typha augustifolia, Polygonum cuspidatum, Crataegus pinnatifida, Polygonum multiflorum inhibited the HMG CoA reductase activity by 53%, 42%, 37%, and 33% respectively. Results suggest that these plant extracts might play important roles in the regulation of the cholesterol metabolism in vivo.

• Food Science and Preservation
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• v.18 no.4
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• pp.620-625
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• 2011

This is a part of the study on the food materials that are effective for diabetes treatment and for use in the development of functional bread products. In this study, various commercially available Oriental medicines with the intestinal absorption enzyme called ${\alpha}$-glucosidase, which is known to be effective for diabetes treatment, were explored. According to the research results on the water and methanol in 200 kinds of Oriental medicines, which were separated by layer to investigate the inhibitory activity of ${\alpha}$-glucosidase, Astragalus membranaceus (70.9%) in the water layer and Pericaeta communissima (72.9%) in the MeOH layer showed a strong inhibitory effect of over 70%. Myristica fragrans (69%), Morus alba (66.9%), Schisandra chinensis (65%), Panax notoginsens (63.9%), Anthriscus sylvestris (62.9%), Asparagus cochinchinensis (62.1%), Erycibe obtusifolia (60.9%), Polygonum cuspidatum (60.7%), Atractylodes lancea (60.2%), and Perilla frutescens (60.2%) in the water layer, and Codonopsis pilosula (67.8%), Prunus persica batsch (67.6%), Sinomenium acutum (63.5%), and Malvae semen (61.6%) in the MeOH layer, showed a more than 60% inhibitory effect. Thirty one species, including Polygonatum sibiricum (59.8%), Medicata fementata (59.7%), Alisma canaliculatum (59.5%), Coix lacryma-jobi (59.2%), Asiasarum sieboldi (59.0%), and Bupleurum falcatum (53.0%), in the water layer, and 10 species [Quisqualis indica (58.8%), Lycium chinense (58.3%), Trichosanthes kirilowii (58.0%), Thuja orientalis (55.9%), Bombyx mori (55.6%), Gallus domesticus (55.4%), Aralia continentalis (55.3%), Cibotium barometz (52.7%), Euphorbia pekinensis (52.7%), and Dolichos lablab (52.5%)] in the MeOHlayer, showed a more than 50% inhibitory effect. Therefore, such materials are expected to be the basic materials that will be used for the development of functional materials for diabetes treatment.