• Title/Summary/Keyword: Anti-oxidation

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Anti-oxidation and Anti-atopic Dermatitis Effect of Herbal Wood Vinegar (한방목초액의 항산화 및 항 아토피 효과)

  • Kim, Tagon;Nho, Hwa Jung;Jun, Sang Hui;Kim, Kang Bae;Kim, Donguk
    • Korean Chemical Engineering Research
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    • v.48 no.6
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    • pp.690-694
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    • 2010
  • In this study, herbal wood vinegar including Bambusoideae, Cinnamomi Cortex, Zingiberis Rhizoma was tested to see possibility for cosmetic or skin related medicine. Anti-oxidation effect of herbal wood vinegar was tested by DPPH free radical scavenging activity, and showed 97% inhibition rate at $50{\mu}g/ml$. Anti-bacterial effect was tested by disc diffusion method, and it indicated strong anti-bacterial activity against normal skin flora Staphylococcus aureus. Whitening effect was measured by tyrosinase inhibition assay, and it was lower compared with vitamin C. Stability test was done by MTT assay, and cell toxicity was relatively high. Stability was also checked, and there was not significant change in color, aroma, appearance and pH during storage. Anti-atopic dermatitis test was done by hairless mouse and herbal wood vinegar recovered damaged skin to almost normal condition after 9 days of application. IgE concentration in herbal wood vinegar treated mouse was also reduced 30% compared with control. From the study, herbal wood vinegar showed good anti-oxidation, anti-bacterial and anti-atopic dermatitis effect, and had promising application in cosmetic or skin related medicine.

Anti-oxidative and anti-inflammatory effects of aerial parts of Rumex japonicus Houtt. in RAW 264.7 cells (양제엽(羊蹄葉) 메탄올 추출물의 항산화 및 항염증 효과)

  • Cho, Hyun-Jin;Yun, Hyun-Jeong;Park, Sun-Dong
    • The Korea Journal of Herbology
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    • v.26 no.1
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    • pp.87-96
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    • 2011
  • Objectives : The aerial parts of Rumex japonicus Houtt. (RF) is used by traditional clinics to treat parasite infection in East asia. This study aims a verification of anti-oxidative and anti-inflammatory effects of RF methanol extract. Methods : Anti-oxidative effects of RF were measured by scavenging activities of DPPH, superoxide, nitric oxide (NO) and peroxynitrite radicals. And also scavenging activities of anti-oxidation in lipopolysaccharide (LPS)-treated RAW 264.7 cells were measured. The inhibitory effects against the production of inflammatory mediators including NO, prostaglandin $E_2$ ($PGE_2$), tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$), IL-6, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and the translocation of nuclear factor (NF)-${\kappa}B$ in LPS-stimulated RAW 264.7 cells by RF were tested. Results : RF scavenged DPPH, superoxide, NO and peroxynitrite radicals, and RF (at $200{\mu}g/m{\ell}$) reduced the inflammatory mediators definitely. Conclusions : These results indicate that RF may be a potential drug source for oxidative stress related inflammatory diseases.

Effect of anti-skin disorders of ginsenosides- A Systematic Review

  • Lele Cong;Jinli Ma;Yundong Zhang;Yifa Zhou;Xianling Cong;Miao Hao
    • Journal of Ginseng Research
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    • v.47 no.5
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    • pp.605-614
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    • 2023
  • Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play antiaging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.

The Effect of Oxides Additives on Anti-corrosion Properties of Sintered 316L Stainless Steel (STS 316L 소결체의 부식 저항 특성에 미치는 금속산화물 첨가의 영향)

  • Lee, Jong-Pil;Hong, Ji-Hyun;Park, Dong-Kyu;Ahn, In-Shup
    • Journal of Powder Materials
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    • v.22 no.4
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    • pp.271-277
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    • 2015
  • As wrought stainless steel, sintered stainless steel (STS) has excellent high-temperature anti-corrosion even at high temperature of $800^{\circ}C$ and exhibit corrosion resistance in air. The oxidation behavior and oxidation mechanism of the sintered 316L stainless was reported at the high temperature in our previous study. In this study, the effects of additives on high-temperature corrosion resistances were investigated above $800^{\circ}C$ at the various oxides ($SiO_2$, $Al_2O_3$, MgO and $Y_2O_3$) added STS respectively as an oxidation inhibitor. The morphology of the oxide layers were observed by SEM and the oxides phase and composition were confirmed by XRD and EDX. As a result, the weight of STS 316L sintered body increased sharply at $1000^{\circ}C$ and the relative density of specimen decreased as metallic oxide addition increased. Compared with STS 316L sintered parts, weight change ratio corresponding to different oxidation time at $900^{\circ}C$ and $1000^{\circ}C$, decreased gradually with the addition of metallic oxide. The best corrosion resistance properties of STS could be improved in case of using $Y_2O_3$. The oxidation rate was diminished dramatically by suppression the peeling on oxide layers at $Y_2O_3$ added sintered stainless steel.

Anti-wrinkle Effect of Safflower (Carthamus tinctorius) Seed Extract (I) (홍화씨추출물의 피부 주름개선 효과(I))

  • 윤경섭;김미진;김자영;최상원;홍진태
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.1
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    • pp.15-22
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    • 2004
  • Anti-wrinkle Effect of safflower (Carthamus tinctorius L.) seed extract (CTSE) was evaluated by determination of the anti-oxidation, collagen synthesis and elastase inhibition in normal human fibroblast. CTSE showed anti-oxidation and collagen synthesis ability as much as or greater than other phytoestrogenic compounds such as genistein or resveratrol. Consistent with collagen synthesis promotion, CTSE also showed inhibitory effect on elastase activity. In the human skin irritation test, 0.2% CTSE did not show any adverse effect. These results demonstrate that CTSE can be useful as an anti-wrinkle cosmetic ingredient.

Effects of Jowiseungcheung-tang Extract on the Lipid Metabolism, Anti-oxidation and Inflammatory Reflex High Fat Diet Obese Rats (조위승청탕(調胃升淸湯) 추출액이 비만유도 쥐의 지질대사, 항산화계 및 염증반응계에 미치는 영향)

  • Oh, Sung-Won;Kim, Byoung-Woo
    • The Journal of Internal Korean Medicine
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    • v.34 no.1
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    • pp.1-13
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    • 2013
  • Objectives : The purpose of this study was to investigate the effects of Jowiseungcheung-tang (JWSCT) extract on the lipid metabolism, anti-oxidation and inflammatory reflex. Methods : Male Sprague-Dawley rats were fed a high fat diet for 8 weeks and were randomly divided into 4 groups (10 mice in each group): control group, 100 mg/kg JWSCT group, 200 mg/kg JWSCT group, 300 mg/kg JWSCT group. The control group was administered 100 mg/kg of water, but the other three groups were administered 100, 200, 300 mg/kg JWSCT extract for 4 weeks. After 4 weeks, we measured lipid level, thiobarbituric acid reactive substance (TBARS), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and cytokines in plasma and liver. The gene expression level and the ratio of apo-B and apo-E were then investigated by way of reverse transcription -polymerase chain reaction (RT-PCR). Results : In the JWSCT group, compared with the control, free fatty acid, triglyceride, total cholesterol, LDL-cholesterol, TBARS, IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ decreased significantly in plasma and liver. However HDL-cholesterol, IL-10, GSH-Px, SOD and CAT increased. In the JWSCT group, compared with the control, the gene expression level and the ratio of apo-A and apo-E decreased significantly in the RT-PCR analysis. Conclusions : The extract of JWSCT has anti-obesity, anti-inflammatory and anti-oxidant effects.

Inhibitory Effect of Melanogenesis and Anti-inflammatory Effect of Elsholtzia ciliata Extract and Its Application as a Cosmeceutical Ingredient (향유의 멜라닌 생성 억제효과 및 항염효과와 화장품 원료로서의 특성)

  • Lee, Dae-Woo;Kim, Young-Jin;Kim, Young-Sil;Eom, Sang-Yong;Kim, Jong-Heon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.4 s.59
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    • pp.219-225
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    • 2006
  • In this study, we evaluated anti-oxidation, whitening and anti-inflammatory effects of Elsholtzia ciliata extract for use as the cosmeceuticals. Elsholtzia ciliata extracts (30, 70 and 100% methanol extract) exhibited a significant tree radical scavenging effect (up to 80% over 0.025% concentration of 30 and 70% methanol extract, over 0.01% concentration of 100% methanol extract) against DPPH radical generation and showed a significant inhibitory effect (up to 80% over 0.1% concentration) on melanin synthesis in B-16 Melanoma cells. We separated 4 fractions from Elsholtzia ciliata extract (70% methanol extract) by MPLC. The 1st, 2nd, and 3rd fractions showed anti-oxidation (DPPH radical scavenging activity and suppressive effect on Mn-SOD), whitening(inhibitory effect on melanin synthesis) and anti-inflammatory (suppressive effects on $IL-1{\alpha}$, IL-6, COX-2, and total NO synthesis) effects.

Effects of Isatis indigitica on Anti-lipid Peroxidation and Low Density Lipoprotein Oxidation (판람근의 지질과산화 및 저밀도지단백산화에 미치는 영향)

  • 장현진;양기숙
    • YAKHAK HOEJI
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    • v.46 no.6
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    • pp.448-451
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    • 2002
  • Isatis indigotica is commonly used as traditional chinese medicine for antipyretic, antiviral, and detoxifying purpose in China. In order to examine whether it prevents lipid peroxidation, root of Isatis indigotica was extracted with methanol and fractionated with hexane, ethyl acetate, butanol and water. The activity was evaluated by DPPH method and lipid peroxidation in rat liver homogenate and C $u^{++}$ -induced oxidated LDL. The results showed that ethyl acetate fraction and indigo, which is known as its constituent, had significantly anti-lipid peroxidative effects.s.

Oxidation Stability of Regenerated Lubricating Oils (Ⅰ). Properties of Regenerated Oils (潤滑再生油의 酸化安定性能 (第1報) 再生油의 性能)

  • Yun Ho Nha
    • Journal of the Korean Chemical Society
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    • v.18 no.6
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    • pp.443-446
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    • 1974
  • The regenerated lubricating oils for an internal combustion engine, obtained from the sulfuric acid and clay treatment, showed an improved thermal oxidation stability regardless of additives, especially anti-oxidant, originally presented in the oils. It is believed that such improvement is due to the formation of anti-oxidant materials, which is observed by the in crease of 25 % of aromatic compounds.

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