• CELLMED
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• v.8 no.1
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• pp.2.1-2.4
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• 2018

A case of chronic dry cough which was tried to be treated through so many medications in a period of two months, responded very well to a simple ayurvedic remedy composing of a common formulation chosen as per the ayurvedic principles of pathogenesis and management. This case may be an eye opener to the concurrent ayurvedic clinical practice and invites ayurvedic practitioners to stick to their own principles of disease management for obtaining better responses.

• CELLMED
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• v.8 no.3
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• pp.15.1-15.5
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• 2018

Helminthiasis is one of the most common worm diseases which causes a range of adverse health problems in humans. Ayurveda is one of the most prominent and ancient systems of traditional medicines in India. Most Ayurvedic drugs used against intestinal helminths have been developed by traditional wisdom and therefore lack a proper validation through controlled studies. The aim of the present study was to scientifically validate the in vitro efficacy of three common Indian Ayurvedic anthelmintic drugs, viz. Krimimudgar Ras, Kriminol and Vidangasava in relation to the synthetic broad-spectrum anthelmintic drugs, praziquantel and albendazole. The in vitro testing of Ayurvedic anthelmintics was done against an intestinal cestode, Raillietina sp. and a nematode, Syphacia obvelata, employing 10 mg/ml, 30 mg/ml and 50 mg/ml concentrations of each medicine. The anthelmintic efficacy was judged on the basis of paralysis and mortality time of worms after exposing to these Ayurvedic drugs. Of the three tested Ayurvedic medicines, Krimimudgar ras (KR) showed the most prominent efficacy, against both the cestode and nematode parasites. At 50 mg/ml concentration, KR caused mortality of cestodes in $7.53{\pm}0.15hr$, and of nematodes in $7.61{\pm}0.19hr$. Vidangasava was found to be comparatively less effective against the tested helminth parasites. The results of this study indicate that Ayurvedic formulations do possess significant anthelmintic effects, however, an evidence-based research is required to validate all currently used Ayurvedic anthelmintics, using proper controlled studies.

• The Korea Journal of Herbology
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• v.25 no.4
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• pp.161-169
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• 2010

Objectives & Methods : To compare the medicinal herbs between Ayurvedic medicine and traditional Korean medicine(TKM), we took reference of major publications related to Ayurvedic medicinal herbs such as Indian Herbal Remedies, Prime Ayurvedic Plant Drugs, with those of TKM. We selected most widely used 130 herbal species of Ayurvedic medicine and compared the similarities and differences with TKM. Comparative factors were the origin, habitation, synonyms, usage, medicinal parts, and precautions. Results : 1. The medicinal herbs Resinatum Lignum(沈香), Arecae Pericarpium(大腹皮), Arecae Semen(檳榔), Carthami Flos (紅花), Camphorum(樟腦), Crotonis Semen(巴豆), Curculiginis Rhizoma(仙茅) used in TKM did exactly correlate in their origins with those of Ayurvedic medicine. 2. Varieties of allied species were found in their origins. Benincasae Pericarpium(冬瓜皮), and Benincasae Semen(冬瓜子) derive from the same plant Benincasa hispida Cogn. for both Ayurvedic medicine and TKM. Interestingly, B. cerifera Savi. is also claimed for same uses in Ayurvedic medicine. This broadened use of allied species is found in various Ayurvedic herbal medicine such as Cannabis Semen(火麻仁) using Cannabis indica Lam., and Curcuma Longae Rhizoma(薑黃) using Curcuma domestica Valeton. This suggests the possibility of their usage also in TKM. 3. Myrrha(沒藥), and Curculiginis Rhizoma concorded their usage with TKM. While Arecae Pericarpium(大腹皮), Arecae Semen(檳榔), Aquilariae Resinatum Lignum(沈香), Pericarpium(冬瓜皮), Benincasae Semen(冬瓜子), Cannabis Semen(火麻仁), Carthami Flos(紅花), Camphorum(樟腦), Crotonis Semen(巴豆), Curcumae Radix(鬱金), Curcuma Longae Rhizoma(薑黃) and Zedoariae Rhizoma(莪朮) revealed varied efficacies according to their part used or usage forms. Conclusion : Both Ayurvedic medicine and TKM reflect the traditional medicine of its regions where is founded. Mutual understanding improves the capability of coping of diverse ailments of present days and also replacing some plants in the days of increasing threat to our environment. Abundant external applications of various plants found in Ayurvedic medicine were particularly useful for TKM to complement its strength in herbal intake.

• CELLMED
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• v.9 no.4
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• pp.9.1-9.4
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• 2019

Ayurveda is one of the ancient systems of traditional medicine in India, however, there is a lack of proper scientific research and controlled studies on efficacy and toxicity of several Ayurvedic formulations using the methods of modern science, which hinders the proper development of Ayurveda, both in India and abroad. The present study was undertaken to further corroborate the efficacy of some popular anthelmintic Ayurvedic medicines, as evident by the pharmacological effects of Ayurvedic formulations on body surface of a cestode parasite. This study employed a common intestinal cestode of domestic fowl, Raillietina sp., as a model parasite, that was exposed in vitro to different concentrations of three common Indian Ayurvedic anthelmintic drugs, namely Krimimudgar Ras, Kriminol and Vidangasava, and also to a modern anthelmintic drug, praziquantel (PZQ). After the paralysis of parasites, the specimens from the highest drug-treated concentration (50 mg/ml), praziquantel (1 mg/ml), and control groups, were collected and processed for scanning electron microscopic studies to document the effects of drugs on the body surface of parasite. In this study, maximum degree of alterations on parasite body surface was observed in the worms exposed to Krimimudgar Ras, indicating this drug to be highly efficacious against intestinal worms and brings out a transtegumental mode of action on parasite. In conclusion, the findings of present study suggest that of the three Ayurvedic formulations tested, Krimimudgar Ras possesses significant anthelmintic effects, which are mediated through parasite's body surface. Therefore, Krimimudgar Ras may be considered as a reliable anthelmintic Ayurvedic formulation, as validated through this study.

• Fashion & Textile Research Journal
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• v.9 no.4
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• pp.425-430
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• 2007

This study was to present these results as basic data for the effects of Ayurvedic oil and the development of alopecia treatment programs. The results were as follows: 1) After Ayurvedic treatment, the hair density of vertex and occiput were 264.2 hair/$cm^2$ and 299.8 hair/$cm^2$ each. There was the increase of total 29.2% in hair density. 2) The hair growth rates on vertex and occiput after Ayurvedic treatment were 310.8 ${\mu}m$/day and 345.8 ${\mu}m$/day respectively, there was the increase of total 79% in hair growth.

• CELLMED
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• v.7 no.2
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• pp.9.1-9.6
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• 2017

Recurrent Acute Pancreatitis/ Chronic Pancreatitis (RAP/ CP) is generally marked by sudden onset of symptoms like severe abdominal pain, vomiting and weight loss that needs emergency hospitalization. Owing to irreversible and progressive nature of the disease and limitations of conventional treatment, many patients look for an alternative solution. Here, we report data of 250 well diagnosed cases of acute recurring/ chronic pancreatitis, enrolled in between January 1997 to August 2016, in our Ayurvedic clinical practice in Northern part of India. Ayurveda is well recognized as an independent medical system parallel to conventional medicines in India and a subject is free to opt for any system of medicine for the prevention and treatment of any ailment. The subjects were treated with a complex herbo-mineral formulation based on the principles of Rasa Shastra in Ayurveda that deals with the therapeutics of processed metals in the prevention and treatment of diseases. They were also prescribed a regulated balanced diet and lifestyle. Significant improvement has been noted in subjects who have completed the treatment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.9
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• pp.3375-3379
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• 2010

Objective: The purpose of this study was to investigate the characteristics of facial skin parameters (hydration, lipid and pH) on forehead and cheek according to Ayurvedic constitution classification of Vata, Pitta and Kapha. The condition of hydration, lipid and pH in the facial skin was measured using non-invasive diagnostic technique. The collected data was analyzed with the SPSS 16.0 windows statistical program. Design: Eighty-nine Korean female subjects were recruited for this study and the average age of them was $19.9{\pm}0.84$ years. Three groups by the Ayurvedic constitution were classified by questionnaire. Results: There was a significant difference in hydration, lipid and pH according to Ayurvedic constitution. The measurement of hydration on the face depending on the constitution were shown in the order of Pitta, Kapha and Vata (p<0.001). The measurement of lipid on the face depending on the constitution were shown in the order of Kapha, Pitta and Vata (p<0.001, p<0.01). The measurement of pH on the face depending on the constitution were shown in the order of Kapha, Pitta and Vata (p<0.01). Conclusion: Facial skin surface seemed to be dependent on Ayurvedic constitution classification in Korean. These findings indicated that Ayurvedic constitution classification might be a useful esthetic treatment for caring facial skin in the future.

• CELLMED
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• v.2 no.2
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• pp.17.1-17.5
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• 2012

Ayurveda is a nearly 3000 years old traditional medical system of India. Most of the time, people turn to ayurvedic physicians in desperate conditions. Here clinical practices of Ayurveda were initially found effective in the management of migraine among few patients. Later, it was developed as an ayurvedic treatment protocol (ATP) which consists of four herbo-mineral formulations (HMF), three meals and three snacks in a day with eight hours sleep at night. ATP brought significant relief in reducing the frequency, intensity of pain and associated symptoms in the migraine patients. IHS diagnostic criteria was followed to establish the diagnosis of migraine and uniform ATP was prescribed to each patient who were primarily treated by the ayurvedic physicians at their respective clinics. Such observations were presented at appropriate international forums. In an effort to validate the above, the present study carries the details of nine migraine patients who were first diagnosed and treated for migraine by a leading headache expert at Mumbai in India and were then referred to receive ATP. A total number of nine subjects volunteered to this program. Out of those, seven subjects completed 120 days of ATP. Five subjects reported significant improvement in overall symptoms of migraine. All subjects were followed up periodically for four years. No Grade II side effects were observed in any treated case. HMF has also been proved to be safe in experimental studies. Further pharmacological and randomized controlled clinical studies are in progress at the respective departments of a premier medical institute in India.

• CELLMED
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• v.6 no.4
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• pp.27.1-27.4
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• 2016

Anxiety is a common clinical presentation. Primary anxiety poses a significant problem in its management. Many among the current treatment options of anxiety are habit forming causing significant withdrawal symptoms. There are dose dependent responses often associated with drug adversities. Day time sedation is an undesired effect of many drugs used for anxiety management limiting its usage. Ayurveda recommends a bio- physical procedure to manage anxiety. Shirodhara, a dripping procedure is utilized as a front line therapy for anxiety in Ayurveda. Seeing the limitations of conventional biomedical management of anxiety requiring an improvement upon the existing protocols of managements, and also seeing the use of shirodhara for anxiety management in ayurvedic clinics, a pragmatic study to evaluate the effect of shirodhara in generalized anxiety disorder was done. This was a pragmatic study consisting of shirodhara with ksheer bala oil as an intervention upon generalized anxiety disorder patients. The study was conducted upon 13 patients and observations were done for six weeks. The responses observed through the changes in Hamilton Anxiety Scale were evaluated using paired t test to observe the pre-post significance.

• Journal of Pharmacopuncture
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• v.20 no.1
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• pp.36-44
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• 2017

Objectives: The goal of this study was to characterize Suvarna Bhasma Parada Marit by using the Ayurvedic test parameters, physico-chemical tests, and various instrumentation techniques. Methods: Suvarna Bhasma, an Ayurvedic formulation manufactured as per Bharat Bhaishajya Ratnakar 5/8357 (BBR), has been studied using various instrumentation techniques: X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), laser particle size distribution (PSD) analysis, fourier transform infrared spectroscopy (FT-IR), and atomic absorption spectroscopy (AAS), and physico-chemical parameters, such as the loss on drying (LOD), loss on ignition (LOI), and acid insoluble Ash (AIA) were determined. In addition, Ayurvedic tests, such as Rekhapurnatva (enterable in the furrows of the fingers), Varitaratwa (floatable over water), Nirdhoomta (smokeless), Dantagre Kach-Kach (gritty particle feeling between the teeth), were performed. Results: The XRD study showed Suvarna Bhasma to be crystalline in nature and to contain more than 98% gold. The mean size of the gold crystallites was less than 10 microns, and the morphology was globular and irregular. Suvarna Bhasma contains gold as its single and major element, with EDAX and FT-IR spectra showing that it is more than 98% pure gold. The moisture content (LOD) is less than 0.5%, the LOI is less than 2%, and the AIA is not less than 95%. The Ayurvedic tests, as specified above, helped to confirm the quality of Suvarna bhasma prepared as per the text reference (BBR). Conclusion: This chemical characterization of Suvarna Bhasma performed in this study by using modern instrumentation techniques will be helpful in understanding its pharmacological actions and will help in establishing quality protocols and specifications to substantiate the safety, efficacy & quality of Suvarna Bhasma.