• Title/Summary/Keyword: BChE

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Optimal Quantization Bits Decision of Soft-Decision BCH Codes for DVB-RCS NG Systems (DVB-RCS NG 시스템을 위한 연판정 e-BCH 부호의 구현을 위한 최적 양자화 비트 수 결정)

  • Kim, Min-Hyuk;Park, Tae-Doo;Lim, Byeong-Su;Jung, Ji-Won
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.9
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    • pp.1895-1902
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    • 2011
  • The soft-decision e-BCH decoding algorithm based on the Chase algorithm is adopted in DVB-RCS NG systems. For implementation, it is necessary to decide the number of optimal quantization bits when soft-decision e-BCH decoding algorithm is processed. Also, the performance must be satisfied. Therefore, in this paper, when the soft-decision e-BCH decoder is implemented, we select the number of optimal quantization bits using BER performance.

The Study of Synergy between the BchE-k Variant and the ApoE Gene in the Alzheimer Dementia of the Korean Population

  • Shin, Eun-Sim;Yoon, Song-Ro;Choi, Soo-Kyung;Kim, Soo-Young
    • Journal of Genetic Medicine
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    • v.3 no.1
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    • pp.29-32
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    • 1999
  • The Apolipoprotein E type 4 allele (ApoE ${\varepsilon}4$) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease. The BchE-k variant, which is the common variant of the BchE gene, has been reported to show allelic association with AD in subjects who are also carriers of the ${\varepsilon}4$ allele of the ApoE, especially in subjects over the age of 75. This study was performed to evaluate the distribution of the ApoE and the BchE genotypes in the healthy and AD groups and to evaluate the synergy between the BchE-k variant and the ApoE ${\varepsilon}4$ in AD. The ApoE and the BchE genotypes were determined in DNA samples from 610 healthy people and 60 LOAD patients by using ARMS by standard agarose gel electrophoresis. The effect of the ApoE ${\varepsilon}4$ was closely related to AD(p<0.05). A comparison between the AD patients and the healthy individuals, both with the ${\varepsilon}4$ allele, indicated an interaction between the BchE-k and the ApoE ${\varepsilon}4$(p<0.05). The association of the BchE-k with AD was limited to carriers of the ApoE ${\varepsilon}4$ allele, among whom the presence of the BchE-k gave an odds ratio of AD 3.48 (95% C.I. 1.3-9.2). Therefore, these results suggested that further evidence of an association between the ApoE ${\varepsilon}4$ and LOAD, and the BchE-k acts in synergy with the ApoE ${\varepsilon}4$ as a susceptibility gene for AD.

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Production of an Anti-dementia Butyrylcholinesterase Inhibitor from Non-pathogenic Wild Yeast, Saccharomyces cerevisiae WJSL 0113 (비병원성 야생효모 Saccharomyces cerevisiae WJSL 0113으로부터 항치매성 Butyrylcholinesterase 저해물질의 생산)

  • Han, Sang-Min;Park, Seon-Jeong;Jang, Ji-Eun;Lee, Jong-Soo
    • The Korean Journal of Mycology
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    • v.49 no.2
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    • pp.243-248
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    • 2021
  • In this study, screening of potent non-pathogenic wild yeast with high anti-dementia butyrylcholinesterase (BChE) inhibitory activity and production condition of a BChE inhibitor were described. Among 36 non-pathogenic wild yeasts, Saccharomyces cerevisiae WJSL 0113 showed the highest BChE inhibitory activity of 85.2%. The specific BChE inhibitor was maximally produced when S. cerevisiae WJSL 0113 was cultured at 30℃ for 48 h in a yeast extract-peptone-dextrose medium.

A Study on Application of Shortened TPC Algorithm for DVB-RCS NG Systems (DVB-RCS NG시스템에서 Shortened TPC 알고리즘 적용 방안에 관한 연구)

  • Lim, Byeong-Su;Kim, Min-Hyuk;Park, Tae-Doo;Jung, Ji-Won
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.11C
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    • pp.712-719
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    • 2011
  • In this paper, we analyzed the performance of soft decision e-BCH codes which presented in DVB-RCS NG system. However, the performance of soft-decision decoding for e-BCH is not much improved as to increase the iterations. Therefore this paper proposed rate-compatible TPC which makes various coding rates by zero padding the row and/or column to adapt next generation (NG) DVB-RCS system. And so we proposed new model of extended BCH code and researches how to develop performance of extended BCH code.

LDH/ AChE and LDH/BChE Ratios (Paralichthys olivaceus) as Biomarkers of Coastal Pollution on Coast of Korea.

  • Choi Jin-Ho;Kim Dong-Woo;Kim Chang-Mok;Yang Dong Beom
    • Fisheries and Aquatic Sciences
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    • v.2 no.2
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    • pp.167-171
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    • 1999
  • This study was designed to develop biomarkers of coastal pollution using biochemical indices of flounder (Paralichthys olivaceus) by changes in lactate dehydrogenase (LDH) activity in the serum and cholinesterase activities in brain membranes. For this purpose acetylcholiesterase (AChE) activity, butyrylcholinesterase (BChE) activity, LDH/AChE ratio and LDH/BChE ratio of cultured flounders at 5 different sites on the southern coast of Korea were compared to those of wild flounders caught in the Pohang, eastern coast of Korea as a control group. Relatively high LDH activities were measured in the serum of flounders cultured on the southern coast of Korea (0.101-0.145 unit) than those in the Pohang control group (0.093 unit). AChE activities were significantly low $(about\;10-20\%)$ in brain membranes of cultured flounders compared to those in the Pohang control group. The ratios of LDH/AChE and LDH/BChE were consistently higher $(136-178\%,\; 155-214\%)$ in cultured flounders than those of Pohang control group. Thus, we propose that the ratios of LDH/AChE and LDH/BChE in flounders could be applicable for the diagnosis of marine pollution.

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Regulation of Photosynthesis Genes (puf, puc, puhA, bchC, bchE, bchF, and bchI) in Rhodobacter sphaeroides (Rhodobacter sphaeroides에서의 광합성유전자(puf, puc, puhA, bchC, bchE, bchF와 bchI)의 발현조절)

  • Ko, In-Jeong;Kim, Yong-Jin;Lee, Jin-Mok;Shin, Sun-Joo;Oh, Jeong-Il
    • Journal of Life Science
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    • v.16 no.4
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    • pp.632-639
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    • 2006
  • Here we examined the expression patterns and regulation of seven photosynthesis (PS) genes (puf, puc, puhA, bchC, bchE, bchF, and bchI) in the anoxygenic photosynthetic bacterium, Rhodobacter sphaeroides, based on lacZ reporter gene assay. Expression of the tested PS genes, except puhA and bchI, were strongly induced in R. sphaeroides grown under anaerobic conditions relative to that under aerobic conditions. The puhA and bchI genes appear to form the operons together with bchFNBHLM-RSP0290 and crtA, respectively. Expression of the puf, puc, and bchCXYZ operons in R. sphaeroides grown photosynthetically was proportional to the incident light intensity, whereas that of bchFNBHLM(RSP0290-puhA) was inversely related to light intensity. Expression of bchEJG was lowest under medium-light photosynthetic conditions $(10\;W/m^2)$ and highest under high light conditions $(100\;W/m^2)$. The regulation of PS genes by the three major regulatory systems involved in oxygen- and light-sensing in R. sphaeroides is as following: puf and bchC are regulated by both the PpsR repressor and the PrrBA two-component system. The puc operon is under control of PpsR, FnrL, and PrrBA system. Expression of bchE is controlled by FnrL and PrrBA two-component system, whereas bchF is regulated exclusively by PpsR. It was demonstrated that the PpsR repressor is responsible for high-light repression of bchF and that FnrL might be involved in perceiving the cellular redox state in addition to sensing $O_2$ itself.

Low Computational Algorithm of Soft-Decision Extended BCH Decoding Algorithm for Next Generation DVB-RCS Systems (차세대 DVB-RCS 시스템을 위한 저 계산량 연판정 e-BCH 복호 알고리즘)

  • Park, Tae-Doo;Kim, Min-Hyuk;Lim, Byeong-Su;Jung, Ji-Won
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.22 no.7
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    • pp.705-710
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    • 2011
  • In this paper, we proposed the low computational complexity soft-decision e-BCH decoding algorithm based on the Chase algorithm. In order to make the test patterns, it is necessary to re-order the least reliable received symbols. In the process of ordering and finding optimal decoding symbols, high computational complexity is required. Therefore, this paper proposes the method of low computational complexity algorithm for soft-decision e-BCH decoding process.

Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution III. Changes in Cholinesterase Activity of Flounder(Paralichthys olivaceus)in the Yellow Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 III. 황해산 넙치(Paralichthys olivaceus)의 콜린에스테라아제 활성의 변화)

  • Choi, Jin-Ho;Kim, Dong-Woo;Moon, Young-Sil;Park, Chung-Kil;Yang, Dong-Beom
    • Journal of Life Science
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    • v.7 no.1
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    • pp.17-23
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    • 1997
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of maine pollutions by changes in cholinesterase activity of the flounder (Paralichthys olivaceus)in Yellow Sea of Korea. Acetylcholinesterase (AChE) activities in brain and muscle of cultured flounders in Yellow Sea were remarkably lower (40-50% and 40-55%, respectively)than those of wild flounder in Pohang (control) of East Sea, but AChE activities in brain and muscle of wild flounders in Yellow Sea were significantly lower(15-40% and 25-35%, respectively)than those of wild flounder in Pohang of East Sea. Butyrylcholinesterase(BChE) activities in barin and muscle of cultured flounders in Yellow Sea were remarkably lower(70-75% and 65-75%, respectively) than those of wild flounder in Pohang of East Sea, but BChE activities in barin and muscle of wild flounders in Yellow Sea were significantly lower (15-40%and 25-35%, respectively)than those of wild flounder in Pohang of East Sea. Lactate dehydrogenase (LDH) activities in serum of cultured flounders in Yellow Sea were significantly 10-50% higher than those of wild flounder in Pohang of East Sea, but LDH activities in serum of wild flounders in Yellow Sea were significantly 20-25% higher than those of wild flounder in Pohang of East Sea. It suggests that AChE and BChE activities in brain and muscle of cultured and wild flounders of Yellow Sea may be used as the most effective mean in a biochemical markers for diagnosis of pollutant effects by organophosphorus pesticides.

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Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution IX. Changes in Cholinesterase Activity of the Flounder (Paralichthys olivaceus) in the South Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 IX. 남해산 넙치 (Paralichthys olivaceus)의 콜린에스테라아제의 변화)

  • CHOI Jin-Ho;KIM Dong-Woo;PARK Soo-Hyun;PARK Chung-Kil;YANG Dong Beom;LEE Jong-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.1
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    • pp.37-41
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    • 1999
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of marine pollutions by changes in cholinesterase activity of the flounder (Paralichthys olivaceus) in tie South Sea of Korea. Aceflcholinesterase (AChE) activities in brain and muscle of cultured flounders in the South Sea were significantly lower ($10\~20\%$ and $12\~19\%$, respectively) than those of wild flounder in Pohang of the East Sea as a control. Buthrylcholinesterase (BChE) activites in brain and muscle of cultured flounders in the South Sea were also remarkably lower ($25\~40\%$ and $22\~35\%$, respectively) than those of wild flounder in Pohang. Lactate dehydrogenase (LDH) activites in serum of cultured flounders in South Sea were significantly higher ($10\~55\%$) than those of wild flounder in Pohang. It suggests that AChE, BChE and LDH activities of the flounders clould be used as effective biochemical markers for early warning of environmental damages caused by organophosphorus pesticides.

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An In Vitro and In Vivo Cholinesterase Inhibitory Activity of Pistacia khinjuk and Allium sativum Essential Oils

  • Ghajarbeygi, Peyman;Hajhoseini, Ashraf;Hosseini, Motahare-Sadat;Sharifan, Anoosheh
    • Journal of Pharmacopuncture
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    • v.22 no.4
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    • pp.231-238
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    • 2019
  • Objectives: Alzheimer's disease (AD), an overwhelming neurodegenerative disease, has deleterious effects on the brain that consequently causes memory loss and language impairment. This study was intended to investigate the neuroprotective activity of the two essential oils (EOs) from Iranian Pistacia khinjuk (PK) leaves and Allium sativum (AS) cloves against β-Amyloid 25-35 (Aβ25-35) induced elevation of cholinesterase enzymes in AD. Methods: The EOs of PK (PKEO) and AS (ASEO) were prepared and analyzed in terms of extraction yield, phenolic content, and cholinergic markers in vitro. Moreover, both were administered orally to adult male Wistar rats at concentrations of 1, 2, and 3%. The inhibitory potential of PKEO and ASEO was compared with Donepezil (0.75 mg/kg) against the high activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. Results: PKEO reached an inhibition rate of 83.6% and 81.4% against AChE and BChE, respectively. ASEO had lower anti-cholinesterase activity (65.4% and 31.5% for the inhibition AChE and BChE). PKEO was found to have more phenolic content than ASEO. A significantly positive correlation was observed between the total phenolics and anti-cholinesterase potential. In rats, both EOs decreased the enzyme activity in a concentration-dependent manner. As compared with Donepezil, the significant difference in the AChE and BChE inhibition occurred as rats were treated with PKEO 3% (p < 0.05). Conclusion: It could be concluded that PKEO and ASEO are potent inhibitors of AChE and BChE in rats that hold promise to be used for the treatment of AD.