• Title/Summary/Keyword: BMI

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Non-linear Relationship Between Body Mass Index and Lower Urinary Tract Symptoms in Korean Males

  • Choi, Chang Kyun;Kim, Sun A;Jeong, Ji-An;Kweon, Sun-Seog;Shin, Min-Ho
    • Journal of Preventive Medicine and Public Health
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    • v.52 no.3
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    • pp.147-153
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    • 2019
  • Objectives: The purpose of this study was to evaluate the association between body mass index (BMI) and severe lower urinary tract symptoms (LUTS) in Korean males. Methods: This study was conducted on males aged ${\geq}50years$ who participated in the 2011 Korean Community Health Survey. LUTS severity was assessed using the Korean version of the International Prostate Symptom Score (IPSS) questionnaire, and was dichotomized as severe (IPSS >19) and non-severe ($IPSS{\leq}19$). BMI was divided into 6 categories: <18.5, 18.5-22.9, 23.0-24.9, 25.0-27.4, 27.5-29.9, and ${\geq}30.0kg/m^2$. To evaluate the relationship between BMI and LUTS, a survey-weighted multivariate Poisson regression analysis was performed to estimate prevalence rate ratios (PRRs). Age, smoking status, alcohol intake, physical activity, educational level, household income, and comorbidities were adjusted for in the multivariate model. Results: A U-shaped relationship was detected between BMI and severe LUTS. Compared with a BMI of $23.0-24.9kg/m^2$, the PRR for a BMI < $18.5kg/m^2$ was 1.65 (95% confidence interval [CI], 1.35 to 2.02), that for a BMI of $18.5-22.9kg/m^2$ was 1.25 (95% CI, 1.09 to 1.44), that for a BMI of $25.0-27.4kg/m^2$ was 1.20 (95% CI, 1.00 to 1.45), that for a BMI of $27.5-29.9kg/m^2$ was 1.11 (95% CI, 0.83 to 1.47), and that for a BMI ${\geq}30.0kg/m^2$ was 1.85 (95% CI, 1.18 to 2.88). Conclusions: This study showed that both high and low BMI were associated with severe LUTS.

Correlation between Craniovertebral Angle and Body Mass Index in Middle Age for Improvement of Life Care (라이프케어 증진을 위한 중년층에서 두개척추각과 신체지수의 상관관계)

  • Moon, Ok-Kon;Choi, Tae-Seok;Choi, Wan-Seok
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.231-236
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    • 2020
  • The purpose of this study was to investigate the correlation between craniovertebral angle(CVA), age, and body mass index(BMI) in middle-aged people in their 40s and 50s. The forward head posture(FHP) was measured using a posture measuring device using a 3D sensor for 456 healthy men and women. As a result of the study, the middle-aged CVA had a high level of negative correlation with age (r=-.937; p<.01) and a very low level of positive correlation with BMI (r=.071). CVA of middle-aged men had a high negative correlation with age (r=-.932; p<.01) and a very low positive correlation with BMI. There was a correlation (r=.056), whereas, for middle-aged women, there was a high level of negative correlation (r=.939, p<.01) only with age, but had a weak (low level of negative) correlation with BMI. This study suggests that CVA has a significant negative correlation with age in both males and females however, has a weak relationship with BMI.

A Study of Nutrient Intake and Immune Status in Korean Young Women by BMI (체질량지수에 따른 일부 젊은 여성의 영양상태 및 면역상태에 관한 연구)

  • 이현옥
    • Journal of Nutrition and Health
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    • v.32 no.4
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    • pp.430-436
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    • 1999
  • This study investigated the correlations among nutrient intakes, and immune status in Korean young women in relation to body mass index(BMI). Subjects were classified as underweight, normal or overweight, with anthropometric measurements of these three groups significatly different in terms of weight, body fat, waist measurement, hip measurement, waist/hip ratio(WHR), and skindfold thickness(p<0.001). Average vitamin A, vitamin B1, vitamin B2, calcium and zinc levles were lower than the Korean RDA. Vitamin A levels were found to be significantly correlated with BMI(p<0.05). There was no significant difference in total T and B lymphocytes or IgG, IgG, and IgM levels with respect to BMI, but Natural Killer(NK) cell levels were found significantly increased with increased BMI(p<0.05). BMI was also positively correlated with iron intake and negatively correlated with vitamin A intake in the normal group. Based upon this study, further research on nutritional, immune and trace-mineral status of overweight and underweight young women is required for better health promotion in this female populaton.

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Factors Associated with Body Mass Index (BMI) and Physical Activity among Korean Juveniles

  • Jeong, Chankyo;Song, Jong-Kook
    • Korean Journal of Exercise Nutrition
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    • v.14 no.2
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    • pp.81-86
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    • 2010
  • The purpose of this study was to identify the factors associated with child's Body Mass Index (BMI) and physical activity. The participants (n = 133) were Korean juveniles (3rd and 4th graders) and their parents. They completed a questionnaire packet including the SPARK (Sports, Play, and Active Recreation for Kids) survey and the parent equivalent survey. Correlation, multiple linear regression and binary logistic regression analyses were applied to identify the association between child's BMI and 10 factors of SPARK as predict or variables. 25.6% of the participants were classified as overweight (21.1%) or obesity (4.5%). 3 parental factors including mother's BMI and frequency of mother's and father's physical activity were identified as significant predictors of children's BMI. The 10 variables accounted for 28% of the variance (p<.01) in the linear regression model. These results provide insight into parental factors which are related to a child's BMI and physical activity. Parental role modeling which refers to parents' efforts to model an active lifestyle for children plays an important role.

Estimation of Absorbed Dose for Anterior and Posterior Organs with Body Mass Index in Standing Whole Spine Examination (Standing Whole Spine 검사 시 체질량지수 (BMI)에 따른 전방 및 후방장기의 흡수선량 평가)

  • Shim, Ji Na;Lee, Yong-Gu;Lee, Youngjin
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.12
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    • pp.147-151
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    • 2016
  • Automatic exposure control (AEC) is frequently used in many hospitals for Standing Whole Spine examination which is able to control radiation dose with respect to the body type such as body mass index (BMI) and we can measure dose area product (DAP) based on respective patient information. However, few studies have been conducted organ absorbed dose evaluation based on location of patient organ. The purpose of this study was to evaluate the relationships between BMI and organ absorbed dose along with location of patient organ. For that purpose, we calculated absorbed dose with selected 5 patient organ (thyroid, breast, heart, kidney, and pancreas) using a PCXMC simulation tool with measured DAP. According to the results, measured DAP increases with BMI and organ absorbed dose decreases with BMI in anterior organs such as thyroid, breast, and heart. On the other hand, there is no correlation between organ absorbed dose and BMI in posterior organs such as kidney and pancreas. In conclusion, our results demonstrated that the radiation effects are different with respect to BMI and location of patient organ in Standing Whole Spine examination.

Influence on Enlisted Soldiers' Health behavior, Body-shape perception, and Weight control toward the BMI change (현역병의 건강행태, 주관적 체형인식, 체중조절 활동이 BMI 변화에 미치는 영향)

  • Lee, Hyun-Ju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.5
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    • pp.3353-3360
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    • 2015
  • This study was conducted to identify the BMI of enlisted soldiers, to understand the difference between their BMI and that of other men in their age group, and to identify the influence factors of enlisted soldiers' BMI change. The survey has been conducted self-evaluation questionnaire from 23 Feb. 2009 to 31 Mar. 2009 from 4 different forces as methods. Independent-sample T-test, chi-square test and multiple linear regression analysis were used for statistical analysis from 301 collected data. As a result of surveying enlisted soldiers' BMI, their obesity rate 18.6% was lower than 22.1% of other men in their age group. In terms of health behavior, the underweight&normal weight group(2.39) showed higher diet score than the overweight group(2.13), showing that the underweight&normal weight group ate relatively slowly, less spicy and less sweet food compared to the overweight group. The overweight group(2.25) showed lower satisfaction with their body type than the underweight&normal weight group(2.98), while the overweight group(4.01) showed a significantly higher score than the underweight&normal weight group(3.37) for weight control activity. The influence factors of BMI change were diet habit, subjective perception of body type, and weight control activity. In order to improve of enlisted soldiers' BMI, it would be necessary to improve the food service and the snack bars for interventional control of food that influence obesity, rather than personal effort, in addition, education for right body-shape perception and encouraging on weight control activity.

Effects of BMI-1026, A Potent CDK Inhibitor, on Murine Oocyte Maturation and Metaphase II Arrest

  • Choi, Tae-Saeng
    • Reproductive and Developmental Biology
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    • v.31 no.2
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    • pp.71-76
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    • 2007
  • Previous studies have shown that BMI-1026 is a potent inhibitor of the cyclin-dependent kinases (cdk). In cell culture, the compound also arrests G2/M strongly and G1/S and S weakly. Two key kinases, cdk1 (p34cdc2 kinase) and mitogen-activated protein (MAP) kinase (erk1 and 2), perform crucial roles during oocyte maturation and, later, metaphase II (MII) arrest. In mammalian oocytes, both kinases are activated gradually around the time of germinal vesicle breakdown (GVBD) and maintain high activity in eggs arrested at metaphase II. In this study, we examined the effects of BMI-1026 on GVBD and MII arrest in mouse oocytes. BMI-1026 inhibited GVBD of immature oocytes and activated MII-arrested oocytes in a concentration-dependent manner, with more than 90% of oocytes exhibiting GVBD inhibition and MII activation at 100 nM This is approximately 500$\sim$1,000 times more potent than the activity reported for the cdk inhibitors roscovitine (${\sim}50{\mu}M$) and butyrolactone (${\sim}100{\mu}M$). Based on the results of previous in vitro kinase assays, we expected BMI-1026 to inhibit only cdk1 activation in oocytes and eggs, not MAP kinase. However, in our cell-based system, it inhibited the activity of both kinases. We also found that the effect of BMI-1026 is reversible. Our results suggest that BMI-1026 inhibits GVBD and activates MII-arrested oocytes efficiently and reversibly and that it also inhibits both cdk1/histone HI kinase and MAP kinase in mouse oocytes.

A Study on Anthropometric Data of 5th Grade Students with Demographic, Biochemical and Personality Factors (국교 5년생의 체격에 따른 인구학적, 생화학적 요인 및 인성과 기타 요인에 대한 연구)

  • 문현경
    • Journal of Nutrition and Health
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    • v.21 no.4
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    • pp.213-222
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    • 1988
  • The purpose of this study was to investigate physical condition, physical fitness, sociodemographic factors, biochemical factors and personality factors of 5th grade students of elementary school. The number of students surveyed was 760 from each school of urban, middle and rural areas. All data analysis was done by BMI group which is based on previous study. 1) The children whose parents were on low education level and mother had a job had lower BMI values than others. Nine percent of male and 21% of female subjects skipped breakfast almost everyday. The 21.7% of all subjects regularly took nutritive pills, which had no difference in various BMI groups. 2) The physical condition of children had a high correlation with that of parents. 3) The physical fitness in BMI 5 groups was weaker than other groups, especially in male. 4) The contents of blood hemoglobin, cholesterol and glucose and hematocrit value were estimated. In female, the values of hemoglobin content and hematocrit had significant difference between BMI groups, but there are no trends. 5) The impulsiveness of male was the highest in BMI 1 group and the lowest in BMI 5 group among 5 groups. Besides, general activity, reflectivity and sociality in BMI 5 group had a low level. In female, personality factors except sociality didn't show any considerable difference.

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BMI-1026 treatment can induce SAHF formation by activation of Erk1/2

  • Seo, Hyun-Joo;Park, Hye-Jeong;Choi, Hyung-Su;Hwang, So-Yoon;Park, Jeong-Soo;Seong, Yeon-Sun
    • BMB Reports
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    • v.41 no.7
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    • pp.523-528
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    • 2008
  • BMI-1026 is a synthetic aminopyrimidine compound that targets cyclin dependent kinases (cdks) and was initially designed as a potential anticancer drug. Even though it has been well documented that BMI-1026 is a potent cdk inhibitor, little is known about the cellular effects of this compound. In this study, we examined the effects of BMI-1026 treatment on inducing premature senescence and then evaluated the biochemical features of BMI-1026-induced premature senescence. From these experiments we determined that BMI-1026 treatment produced several biochemical features of premature senescence and also stimulated expression of mitogen activated protein kinase (MAPK) family proteins. BMI-1026 treatment caused nuclear translocation of activated Erk1/2 and the formation of senescence associated heterochromatin foci in 5 days. The heterochromatin foci formation was perturbed by inhibition of Erk1/2 activation.

Prospective Study of Central versus Peripheral Obesity in Total Knee Arthroplasty

  • Armstrong, John G.;Morris, Tyler R.;Sebro, Ronnie;Israelite, Craig L.;Kamath, Atul F.
    • Knee surgery & related research
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    • v.30 no.4
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    • pp.319-325
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    • 2018
  • Purpose: Body mass index (BMI) is often used to predict surgical difficulty in patients receiving total knee arthroplasty (TKA); however, BMI neglects variation in the central versus peripheral distribution of adipose tissue. We sought to examine whether anthropometric factors, rather than BMI alone, may serve as a more effective indication of surgical difficulty in TKA. Materials and Methods: We prospectively enrolled 67 patients undergoing primary TKA. Correlation coefficients were used to evaluate the associations of tourniquet time, a surrogate of surgical difficulty, with BMI, pre- and intraoperative anthropometric measurements, and radiographic knee alignment. Similarly, Knee Injury and Osteoarthritis Outcome Score (KOOS) was compared to BMI. Results: Tourniquet time was significantly associated with preoperative inferior knee circumference (p=0.025) and ankle circumference (p=0.003) as well as the intraoperative depth of incision at the quadriceps (p=0.014). BMI was not significantly associated with tourniquet time or any of the radiographic parameters or KOOS scores. Conclusions: Inferior knee circumference, ankle circumference, and depth of incision at the quadriceps (measures of peripheral obesity) are likely better predictors of surgical difficulty than BMI. Further study of alternative surgical indicators should investigate patients that may be deterred from TKA for high BMI, despite relatively low peripheral obesity.