• Title/Summary/Keyword: Berberis

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Effect of Immune Activity on Berberis koreana Palibin by Ultra High Pressure Low Temperature Process (초고압 저온처리에 의한 매자나무의 면역 활성)

  • Jin, Ling;Han, Jae-Gun;Ha, Ji-Hye;Jeong, Hyang-Suk;Kwon, Min-Chul;Ahn, Ju-Hee;Kim, Jin-Chul;Choi, Geun-Pyo;Chung, Eul-Kwon;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.16 no.6
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    • pp.439-445
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    • 2008
  • This study was performed to investigate a methodology of improving immune activities of Berberis koreana Palibin by ultra high pressure on low temperature extraction process. Extraction yield was enhanced up to more than 35% by above process, compare to the control and extraction average. The cytotoxicity on human kidney cell (HEK293) was showed below 20.4%, 21.6% in adding 1.0 mg/ml of the highest concentration. Generally, the extracts by ultra high pressure extraction process showed less toxicity about 5% than the other processes. It could tell that toxic materials that existing in the plant could be reduced or broken by ultra high pressure process due to can be broken bond such the hydrogen bond, the electrostatic bond, the van der Waals bond, and the hydrophobic bond, can be broken by high pressure. The result could be employed to develop a new type of functional food from B. koreana Palibin by low temperature high pressure process.

Morphological Variation of Berberis amurensis Complex (Berberis amurensis complex의 형태 변이 분석)

  • Hyun, Chang-Woo;Kim, Young-Dong
    • Korean Journal of Plant Taxonomy
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    • v.38 no.2
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    • pp.93-109
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    • 2008
  • The morphological variation was analysed to examine previous hypotheses on the taxonomy of B. amurensis complex which includes B. amurensis Rupr. var. amurensis, B. amurensis var. quelpaertensis (Nakai) Nakai and B. amurensis var. latifolia Nakai. The results from the univariational and principal components analyses employing 22 putatively diagnostic characters indicate that B. amurensis var. quelpaertensis is distinct from var. amurensis in the length and width of leaves, angle of leaf apex, distance between spinose teeth, length of internode, number of flowers per inflorescence, whereas B. amurensis var. latifolia is different from other varieties in the angle of leaf apex and leaf length/width ratio. In principal component analysis, the characters of the leaf including leaf width and length were the main characteristics to distinguish those three taxa. The evidence both from the principal components analyses and current geographical distribution pattern suggest that retaining the varietal status for the two taxa, B. amurensis var. latifolia and B. amurensis var. quelpaertensis is reasonable.

A study on the fruit color characteristics and persisting period of deciduous woody landscape plants in Middle area of Korea (중부지방 낙엽조경수목의 열매색 특성 및 지속 기간에 관한 연구)

  • 서병기;심경구;정해준;심재성
    • Journal of the Korean Institute of Landscape Architecture
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    • v.23 no.3
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    • pp.144-154
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    • 1995
  • The fruit color characteristics and persisting period of deciduous woody landscape plants were investigated through the field survey in Suwon region from January 1, 1992 to March 20, 1993. The summary of the study results was as follows; The total fruit color persisting period was about 320 days from May 1, 1992 when Prunus mume was beginning of fruit coloring, to March 20, 1993 when the fruits of Platanus occidentalis and platanus X acerifolia were persisting. And the plants of fruit persisting period over 60 days after leaf falling were Vibumum erosum, Ilex serrata, Ilex verticillata 'Christmas Cheer', Platanus X acerifolia, Platanus occidentalis, Berberis thunbergii 'Atropupurea', Ligustrum obtusifolium. According to the KBS standard color number, 52.6% of of the fruit color were red, 18.9% yellow, 11.6% black, green 9.5%, white 2.1%, violet 1.1%, and red is followed black 4.2%. Evodia daniellii, Ilex verticillata 'Christmas Cheer', Ilex serrata, Ginkgo biloba, Lindera obtusiloba, and Lindera erythrocarpa should be planted male and female species together for fruits. We got the new information on the fruit color characteritics and persisting period of Malus 'Hopa', Malus 'Almey', Malus 'Pioneer X', Acer rubrum, Malus prunifolia, Pyrus serotina, Berberis thunbergii 'Atropurpurea', Vibumum rhytidophyllum, Rosa spp. Vitis vinifera, Vaccinium angustifolium, Ilex verticillata 'Christmas Cheer', Magnolia stellata, Aronia arbutifolia, Sorbus alnifolia, Lonicera japonica var. aueroreticulta, and Ligustrum X vicaryi. And we need to introduce new cultivars of woody landscape plants including Malus spp, Berberis spp, Sorbus alnifolia yellow autumn leaf clone etc. for the better planting design. The fruit persisting period of woody landscape plants studied by fruit name was that sorosis 276 days, samara 155 days, legume 153 days, hip 133 days, pome was 124 days, drupe 92 days, berry 73 days, capsule 67 days, follicle 55 days and nut 52 days respectively.

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The Effect of Extracts of Berberis koreana Bark by Lactobacillus Fermentation on the Concentration of Serotonin and Melatonin in the Serum of Treated ICR Mice (유산균 발효된 매자나무 추출물이 마우스 혈청중의 Melatonin 및 Serotonin의 함량에 미치는 영향)

  • Ling, Jin;Kim, Ji-Seon;Seo, Yong-Chang;Choi, Woon-Yong;Ahn, Ju-Hee;Ma, Choong-Je;Yoon, Chang-Soon;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.2
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    • pp.117-125
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    • 2011
  • This study was to investigate the effect of fermentation extracts on the concentration of serotonin and melatonin in the serum of the ICR mice. The ICR mice were divided into water control group, lactobacillus fermentation solution including (Lactobacillus paracasei and Bifidobacterium longum B6) control group, positive control group (milk and doxylamine succinate), negative control group (caffein) and the groups treated with the extracts of Berberis koreana bark (WE: water extracts, FE-L.P: fermentation extracts of Lactobacillus paracasei, FE-B.L: fermentation extracts of Bifidobacterium longum B6). After ten-day feeding treatment, the mean concentration of serotonin for water control, WE, FE-L.P and FEB. L group was 134.72, 183.01, 232.09 and $223.78 ng/m{\ell}$, respectively. The mean concentration for FE-L.P and FE-B.L group were approximately 66% larger than that for water control group. The mean concentration of melatonin for water control, WE, FE-L.P and FE-B.L group was 76.92, 106.66, 157.56 and $141.81pg/m{\ell}$, respectively. The mean concentration of melatonin for FE-L.P and FE-B.L group were also larger than that for water control group. Our results indicated that the fermentation extracts of Berberis koreana bark have relatively greater potential to induce secretion of serotonin and melatonin. Therefore, the fermentation extracts have antidepressant effect.

Enhancement of Cosmeceutical Activities of Berberis koreana Bark by High Pressure and Ultrasonification Extraction Processes (초고압 및 초음파 추출공정을 이용한 매자나무 수피의 향장활성 증진)

  • Ling, Jin;Ha, Ji-Hye;Choi, Yoon-Yong;Seo, Yong-Chang;Kim, Ji-Seon;Kim, Young-Ock;Cha, Seon-Woo;Kim, Jin-Chul;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.1
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    • pp.54-65
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    • 2011
  • This study was performed to investigate the enhancement of cosmeceutical activities of Berberis koreana bark by different extraction processes. The extracts are WE (water extract at $100^{\circ}C$, control), USE (ultrasonification for 1 hours at $60^{\circ}C$ with water), HPE (high pressure for 5 minutes at $60^{\circ}C$ with water) and USE + HPE (ultrasonification process for 1 hours after high pressure for 5 minutes at $60^{\circ}C$ with water), respectively. The cytotoxicity of the extracts was in the range of 24.02~26.94% at 1.0 mg/ml concentration. The USE + HPE showed the lowest cytotoxicity. Compared to the WE, total phenolic and flavonoid contents in the USE + HPE increased to 121.5% and 154.2%. The USE + HPE showed the highest activity at 1.0 mg/ml concentration in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging, inhibition activity of xanthine oxidase and superoxide dismutase (SOD)-like test, respectively. Tyrosinase inhibition of WE, USE, HPE and USE + HPE at 1.0 mg/ml concentration was measured as 17.72, 19.62, 22.83 and 24.16%, respectively. Hyaluronidase inhibition activities of the USE + HPE were higher than 20.8%~29.5% of the WE. Our results suggested that the extracts from ultrasonification process after high pressure extraction has relatively high cosmeceutical activities, and that the bark of Berberis koreana could be considered as a candidate of new functional cosmetic agents.

Correlation Analysis between Forest Vegetation Type and Environment Factor in Mt. Hwaak (화악산의 산림군락과 환경요인의 상관관계 분석)

  • Yun, Chung-Weon;Kim, Hye-Jin;Yang, Hee-Moon;Lim, Jong-Hwan;Kim, Young-Kul;Shin, Joon-Hwan;Lee, Byeng-Cheon
    • Journal of Environmental Science International
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    • v.18 no.5
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    • pp.579-588
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    • 2009
  • The purpose of this study was to explain relationship between community structure and their environment variables in Mt. Hwaak. Samples were collected by 101 plots using ZM phytosociological method and followed by cluster, importance value and canonical correspondence analysis. The forest vegetation classified into 8 community types such as Pinus densiflora community, Berberis amurensis community, Betula ermani community, Betula schmidtii community, Larix leptolepis community, Pinus koraiensis community, Cornus controversa community and Salix koreensis community. Altitude was considered as the highest factor correlated to the community types. Berberis amurensis community and Betula ermani community were located in upper slope area of high elevation, Comus controversa community and Salix koreensis community in valley area, and Pinus densiflora community in ridge area, respectively.

Diversity and Bioactive Potential of Culturable Fungal Endophytes of Medicinal Shrub Berberis aristata DC.: A First Report

  • Sharma, Supriya;Gupta, Suruchi;Dhar, Manoj K.;Kaul, Sanjana
    • Mycobiology
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    • v.46 no.4
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    • pp.370-381
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    • 2018
  • Bioactive natural compounds, isolated from fungal endophytes, play a promising role in the search for novel drugs. They are an inspiring source for researchers due to their enormous structural diversity and complexity. During the present study fungal endophytes were isolated from a well-known medicinal shrub, Berberis aristata DC. and were explored for their antagonistic and antioxidant potential. B. aristata, an important medicinal shrub with remarkable pharmacological properties, is native to Northern Himalayan region. A total of 131 endophytic fungal isolates belonging to eighteen species and nine genera were obtained from three hundred and thirty surface sterilized segments of different tissues of B. aristata. The isolated fungi were classified on the basis of morphological and molecular analysis. Diversity and species richness was found to be higher in leaf tissues as compared to root and stem. Antibacterial activity demonstrated that the crude ethyl acetate extract of 80% isolates exhibited significant results against one or more bacterial pathogens. Ethyl acetate extract of Alternaria macrospora was found to have potential antibacterial activity. Significant antioxidant activity was also found in crude ethyl acetate extracts of Alternaria alternata and Aspergillus flavus. Similarly, antagonistic activity of the fungal endophytes revealed that all antagonists possessed inhibition potential against more than one fungal pathogen. This study is an important step towards tapping endophytic fungal diversity for bioactive metabolites which could be a step forward towards development of novel therapeutic agents.

Enhancement of the Antioxidant and Anticancer Activities of Berberis koreana Bark by Using a Low Temperature and High-Pressure Extraction Process (저온고압 추출공정을 이용한 매자나무 수피의 항산화 및 항암활성 증진)

  • Jin, Ling;Ha, Ji-Hye;Jeong, Myoung-Hoon;Chung, Eul-Kwon;Chung, Ae-Ran;Kim, Jin-Chul;Ahn, Ju-Hee;Lee, Hyeon-Yong
    • Korean Journal of Food Science and Technology
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    • v.41 no.3
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    • pp.284-291
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    • 2009
  • This study was conducted to characterize the enhanced antioxidant and anticancer activities of Berberis koreana bark following a low temperature and high pressure extraction process. The results indicate that the B. koreana bark extracted as described showed a 93% increase in DPPH radical scavenging activity. Inhibition activity of xanthine oxidase was highest by this extraction process. In addition the growth of human lung cancer cells (A549), human stomach cancer cells (AGS), human breast cancer cells (MCF-7) and human liver cancer cells (Hep3B) were inhibited by 70.8%, 86.2%, 84.3% and 62.5% respectively. These data indicate that this low temperature and high pressure extraction technique results in the efficient extraction of bioactive compounds from rigid plant materials. This process could also be combined with other techniques to improve extraction yields and identify new biologically active substances from relatively hard plants.

Enhancement of Antioxidant Activities of Bark of Berberis koreana Palibin by Lactic Acid Fermentation (유산균 발효를 통한 매자나무 수피부의 항산화 활성 증진)

  • Ha, Ji-Hye;Jeong, Myoung-Hoon;Seo, Yong-Chang;Choi, Woon-Yong;Kim, Ji-Seon;Kim, Haeng-Hoon;Ahn, Ju-Hee;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.6
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    • pp.421-428
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    • 2010
  • The bark of Berberis koreana Palibin was fermented by Bifidobacterium longum B6 and Lactobacillus paracasei at $37^{\circ}C$ for 72 hour, then extracted by water solvent at $100^{\circ}C$ for 180 min. Total pholyphenol and flavonoid contents were improved by fermentation process, compared to conventional water extraction. The barks of B. koreana Palibin extracts by B. longum B6 (FE-B.L.) and by L. paracasei (FE-L.P.) showed 17% and 16% cytotoxicity on human normal cell lines(HEK293) at 1.0 mg/$m{\ell}$ of the highest concentration, respectively, which was about 3~5% lower than 20% from normal extracts (NE). DPPH radical scavenging activity of the FE-B.L. and FE-L.P. were about 73% and 75.9% higher than 56.8% of NE. The highest inhibitory potency on xathine oxidase and superoxide dismutase (SOD)-like activities were also measured as 31.9% and 61.9% by adding FE-L.P. of 1.0 mg/$m{\ell}$. On tyrosinase inhibition test, the FE-L.P. showed highest activity as 75.9% at 1.0 mg/$m{\ell}$. Generally, FE-L.P. showed higher antioxidant activities as well as higher tyrosinase inhibition activity, possibly due to high contents of total pholyphenol and flavonoid. In general, fermentation of barks of B. koreana Palibin has relatively better biological activities than normal extracts. Specifically, the extracts fermented by L. paracasei showed higher activities than that from B. longum B6.