• Title/Summary/Keyword: Bis-(hydroxyphenyl) diselenide

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Synthesis of New Diselenide Compounds as Anti-Inflammatory Agents

  • Shen, Liulan;Shin, Kyung-Min;Lee, Kyung-Tae;Jeong, Jin-Hyun
    • Archives of Pharmacal Research
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    • v.27 no.8
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    • pp.816-819
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    • 2004
  • Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine induc-ers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphe-nyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as anti-inflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.