• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.4
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• pp.15-24
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• 2014

Objectives: There were only small studies about the difference of the quality of life depending on blood stasis. We investigated that the blood stasis made the differences of quality of life. Methods: We recruited the participants stratified according to age and gender. The participants were assessed independently by two Korean medicine doctors more than 7 years of clinical experiences whether or not with blood stasis. And they responded at the questionnaire associated with blood stasis and SF-36. The analysis was done with IBM SPSS Statistics (ver. 21). Results: Total 101 participants were checked for with/without blood stasis. 40 participants were accord in the diagnosis with blood stasis by two doctors. Two researchers coincided in diagnosis with non-blood stasis in 42 participants. 19 participants showed the discrepancy between the assessment of blood stasis and they were classified as non-blood stasis. The mean age in group of blood stasis was $44.07{\pm}11.65$, it was not shown the significant difference comparing non-blood stasis group. The subscale of physical function (PF), role-physical (RP), bodily pain (BP), general health (GH), vitality (VT), mental health (MH) and role emotional (RE) in SF-36 were significantly low in the group of blood stasis. Blood test including biochemistry, fibrinogen, prothrombin time and D-dimer was not in abnormal range according to blood stasis without CRP. Conclusions: The patients that diagnosed of blood stasis showed the bad physical health status, and partially bad mental health. It is necessary to investigate whether Korean traditional treatment for blood stasis would be made improvement for quality of life. Moreover, the standardization of diagnosis on blood stasis would be needed.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.1
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• pp.84-97
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• 2005

Background and and purpose : The aim of this study is to define the concept and to arrange symptoms of Blood stasis(瘀血) by review of other thesises, literatures connected with it and reserch trend, in order to making a questionnaire of Blood stasis(瘀血) Methods: By review of other thesises and literatures connected with it, we defined the concept and arranged. symptoms of Blood stasis(瘀血). Results: The concept of Blood stasis(瘀血) is summarized as stasis of blood, pollutant of blood and external blood of vessel. The causes and Symptoms of blood stasis is arranged. Conclusion: Review of literatures led to the selection of 48 items describing blood stasis pattern(瘀血證)

• Herbal Formula Science
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• v.21 no.1
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• pp.1-15
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• 2013

Objectives : This article is a study on to which categories of modern diseases blood stasis patterns are assigned and the meaning of blood stasis interpreted with perspectives of Korean Medicine and modern medicine. Methods : We reviewed "Neijing", "Shanghanlun", "Yilingaicuo", "Xuezhenglun" and other books and modern clinical papers related with blood stasis. Results : 1. Blood stasis patterns are related with disorders of hemorrheology, hemodynamics, platelet function, microcirculation, microelements and endothelial damage. 2. From the types of syndrome differentiation, diverse diseases classified in type of qi deficiency with blood stasis and type of blood stasis due to qi stagnation are reported, which reflects qi and blood are closely connected. And many diseases are classified in type of kidney deficiency with blood stasis, which has something in common with chronic diseases can achieve effect from treatment considering blood stasis. 3. Diseases related with kidney involve menopausal disorder, mazoplasia, prostatitis, erectile dysfunction, chronic nephritis, renal calculus, osteoporosis and bursitis. Diseases related with heart involve coronary artery disease, arrhythmia and cerebral thrombosis. Diseases related with spleen involve gastritis, colonitis and digestive organ ulcer. Diseases related with liver involve hepatitis, hyperthyroidism and stroke. Diseases related with lung involve neurodermatitis, bronchitis and paranasal sinusitis. Conclusions : Blood stasis pattern which is one of the areas to draw medicine's attention has broad clinical application.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.421-433
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• 2007

Objectives : This study was performed to evaluate the relationships among blood-stasis. cardio-ankle vascular index(CAVI) and cardiovascular risk. Methods : We obtained general characteristics. blood-stasis score and CAVI from 150 stroke patients. Blood-stasis score was evaluated by blood-stasis criteria. Cardiovascular risk (the following. Stuart's risk score) was evaluated by Stuart's risk scoring scale. We divided subjects into a blood-stasis group and a non blood-stasis group by blood-stasis scores. high CAVI and normal CAVI groupsby CAVI. We compared the general characteristics. CAVI (excluded from comparison between high CAVI group and normal CAVI group), Stuart's risk score and blood-stasis score (excluded from comparison between blood-stasis group and non blood-stasis group) between each pair of groups. Pearson correlation analysis was applied to examine the relationship between blood stasis score and CAVI, blood stasis score and Stuart's risk score. CAVI and Stuart's risk score. Results : The blood-stasis group had significantly higher CAVI and Stuart's risk scores than the non blood stasis group. The high CAVI group had significantly higher blood-stasis score and Stuart's risk score than the normalCAVI group. In correlation analysis. there were significant positive relationship between blood stasis score and Stuart's risk score, CAVI and Stuart's risk score. and blood stasis score and CAVI. Conclusions : This study suggeststhat there is a significant relationship among blood stasis,CAVI and cardiovascular risk.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.148-160
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• 2009

Purpose: We intended to observe the correlations between Primary dysmenorrhea severity and Questionnaires for Blood Stasis Pattern. Methods: After initial approval by Kyung-Hee University Oriental Medical Hospital Institutional Review Board of Clinical Trials, volunteers for the clinical trial were recruited. We selected the 52 primary dysmenorrhea patients by the screening tests (clinical examination and inquiry). The severity of dysmenorrhea was evaluated by VAS (Visual Analog Scale), VRS (Verbal Rating Scale) & MVRS (Multidimensional Verbal Rating Scale). The severity of Blood Stasis was evaluated by Questionnaires for Blood Stasis Pattern. For statistics, we used Spearman's rho correlations, SPSS 13.0 for windows. Results: In case of VAS, though two items (眼瞼下靑紫, 便黑) of Questionnaires for Blood Stasis Pattern were correlated, total score & discriminant function score of Questionnaires for Blood Stasis Pattern were not correlated. In case of VRS, though two items (小腹痛, 夜間痛) of Questionnaires for Blood Stasis Pattern were correlated, total score & discriminant function score of Questionnaires for Blood Stasis Pattern were not correlated. In case of MVRS, though one items (久痺症) of Questionnaires for Blood Stasis Pattern were correlated, total score & discriminant function score of Questionnaires for Blood Stasis Pattern were not correlated. Conclusion: Though the results showed partial correlation of Primary dysmenorrhea severity and Questionnaires for Blood Stasis Pattern, we need further study after improvement and complementation of Questionnaires for Blood Stasis Pattern.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.1
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• pp.92-108
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• 2013

Objectives: The aim of this study is to understand current status in diagnosis of blood stasis for making a questionnaire of blood stasis specially designed for Korean obstetrics & gynecology. Methods: We searched concept of blood stasis presented in the textbook of chinese Korean obstetrics & gynecology and reviewed papers concerning diagnosis of blood stasis published in South Korea, Japan and China recently. Results: From the textbooks & papers concerning diagnosis of blood stasis, there was no specialized diagnostic guidelines with Korean obstetrics & gynecology and some gynecological symptoms, and diseases were contained in each criteria. Conclusions: Recent studies had a relatively unified awareness in diagnosis of blood stasis and we need an additional criteria for signs and symptoms within Korean obstetrics & gynecology to improve clinical efficiency.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.22 no.1
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• pp.1-10
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• 2018

Objectives The purpose of this study is to compare the representative differential diagnosis methods of blood stasis pattern used in Korea, China and Japan, and then to characterize each diagnostic method. Methods Through the journal databases, we have selected representative tools that were developed for differential diagnosis of blood stasis pattern in Korea, China and Japan. In order to characterize the selected check-lists or questionnaires, we investigated the number of items, contents, score calculation method, internal consistency, and accuracy of each selected tool. Results A total of four diagnostic tools were finally selected; quantitative diagnosis scale of blood stasis syndrome (QDSBSS), diagnostic criteria for blood stasis (DCBS), blood stasis questionnaire (BSQ), and blood stasis syndrome questionnaire (BSSQ). The key points in the differential diagnosis for blood stasis were different for each of the diagnostic tool. The key point was oral mucosa (including tongue) status in the QDSBSS. Meanwhile it was abdominal pain/resistance in the DCBS, and general pain in the BSQ. Accuracy of the QDSBSS, the BSQ and the BSSQ were powerful but all of them was not generalized. Conclusions Therefore, it is desirable to select and apply a plurality of appropriate tools according to the characteristics of the blood stasis patients.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.4
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• pp.281-288
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• 2015

This paper researches the features of blood stasis theory of Wangqingren, who wrote 『Yilingaicuo』 that greatly contributed in the development of blood stasis theory at Qing dynasty period. And the disease cause, disease mechanism of blood stasis and scope of modern diseases related with blood stasis are studied by research on clinical papers which used 33 prescriptions in 『Yilingaicuo』 in modern times. Research on the features of blood stasis theory of Wangqingren is proceeded by referring to the annotations of 『Yilingaicuopingyi』 and the papers which related with blood stasis from Korea and China. And clinical papers are searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) to analyse the scope of modern diseases related with blood stasis. The features of blood stasis theory in 『Yilingaicuo』 expanded the range of existing theory. Wangqingren thought that chronic disease, weird disease, the disease of no effect from normal treatments were related with blood stasis. And he attached great importance to qi and blood and thought that the main pathogenesis of blood stasis was qi deficiency. And a lot of Astragalus membranaceus Bunge were combined in many prescriptions to reinforce qi. He also used different herbs according to the location of the disease. Musk and Allium fistulosum were used for the disease located at head or upper part of the patient's trunk. Bupleurum falcatum L., Aurantii Fructus Pericarpium and Platycodon grandiflorum A. De Candolle were used for the disease located at thorax. Cyperus rotundus L., Linderae Radix and Aurantii Fructus Pericarpium were used for the disease located at the stomach or below the costal angle. Foeniculi Fructus and Corydalis remota were used for the disease located at belly or lower part of the patient's trunk. Trogopterorum Faeces, myrrha, Cyperus rotundus L. and Cnidium officinale were used for the disease located at extremity or joint.

• Journal of Korean Medical classics
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• v.24 no.6
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• pp.29-38
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• 2011

The concept of Blood Stasis had been cognized merely as a sign in disorder of blood circulation since "Huangjenaegyeong(黃帝內經)" until "Sanhanron(傷寒論)" and "Geumgweyoryak(金匱要略)" started to describe, explain and apply independent symptom of blood stasis to practice. In this article, establishing the estimate feature of symptom of blood stasis in "Geumgweyoryak(金匱要略)" is the main subject, in sequence the pathological mechanism and targets of prescriptions suggested in "Geumgweyoryak(金匱要略)" are analyzed and restructured. In conclusion, the symptom of blood stasis in "Geumgweyoryak(金匱要略)" is caused not only from disorder of blood circulation but also from metal depression, therefore there are always appearances of excessive and deficient status simultaneously, in the process of symptom. The research on concept of blood stasis from the literatures in early ages will be the basis of future studies about disease of circulation in Korean Traditional Medicine.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.3
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• pp.45-55
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• 2011

Objectives : The main purpose of this study is to investigate the efficacy of Kyejibokryong-whan(Guizhifuling-wan) and examine the blood stasis for patients with motor vehicle accident. Methods : Of the patients who have visited Dong-Shin university oriental hospital for general pan due to motor vehicle accident from June 2010 to November 2010, we enrolled 29 patients and performed blood stasis diagnosis. Patients were divided into groups according to blood stasis findings. Patients who had more than twenty blood stasis diagnosis point were classified as blood stasis group. Patients who had under twenty blood stasis diagnosis point were classified as non blood stasis group. We administered Kyejibokryong-whan(Guizhifuling-wan) to all group. The effect was assessed by VAS(visual analogue scale), SF-MPQ(short form-McGill pain questionnaire) ODI(Oswestry disability index) & NDI(neck disability index). Results : The pain & function index decreased in both groups after treatment. Conclusions : The difference between blood stasis group and non blood stasis group were not significant at after treatment stage. This data suggested that the method of classifying blood stasis is useful and the Kyejibokryong-whan(Guizhifuling-wan) can be effective means that decrease pain caused by motor vehicle accident.