• Title/Summary/Keyword: Blood-glucose meter

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Design and Implementation of a Blood-Glucose Meter to Reduce Hematocrit Interference (적혈구 용적률 간섭 보정을 위한 혈당 측정 기기의 설계 및 구현)

  • Cho, Hyuntae
    • IEMEK Journal of Embedded Systems and Applications
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    • v.15 no.4
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    • pp.167-175
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    • 2020
  • A blood-glucose meter is one of the in vitro diagnostic devices to measure and control the glucose concentration of diabetics. In order to measure the glucose level in the blood, the common method is to measure the amount of electrons, that is, the output current generated by glucose oxidation after a blood sample is inserted into the test strip containing an enzyme. The hematocrit is an obstacle in measuring accurate blood glucose concentration. This paper deals with the design and implementation of a blood-glucose meter to correct the hematocrit interference. We propose a sequential method which measures impedance using the alternating current and then measures glucose in the blood using the direct current. In addition, this paper introduces how to use commercial glucose strips based on the proposed system. Finally, we conducted the performance evaluation of the proposed system by comparing the measured current and impedance with those of the references. As a result, the standard deviation of the current measurement is approximately 0.6nA and the impedance measurement error for measuring the hematocrit is approximately within 1%. The proposed system will improve the accuracy of the conventional blood-glucose meter by reducing the hematocrit interference.

Development of Reliability Demonstration Test for Personal Blood Glucose Meters (개인용 혈당측정기의 신뢰성 보증시험 개발)

  • Kim, Gi-Young;Park, Ho-Joon;Park, Chan-Soo;Ham, Jung-Keol;Jang, Joong Soon
    • Journal of Applied Reliability
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    • v.13 no.4
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    • pp.299-307
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    • 2013
  • The value of blood sugar is measured by a personal blood glucose meter which consists of two parts: a glucose strip and a blood glucose meter. A personal blood glucose meter makes use of electric media which are composed of glucose oxidase and electron. This study is to propose a method of reliability demonstration test derived from field data analysis and FMEA(Failure Mode and Effect Analysis). Detailed Conditions for reliability demonstration test are selected from the comparison of various failure mechanisms. The most dominant failure mechanism is wear-out which is caused by strip insertion/extraction. The testing device that can reproduce the failure mechanism of strip insertion/extraction is made to conduct reliability demonstration test. Using the testing device, it is confirmed that target lifetime of selected devices is more than 2 years.

Blood Glucose Measurement Principles of Non-invasive Blood Glucose Meter: Focused on the Detection Methods of Blood Glucose (무채혈 혈당 측정기의 혈당 측정 원리: 혈당 검출방법 중심으로)

  • Ahn, Wonsik;Kim, Jin-Tae
    • Journal of Biomedical Engineering Research
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    • v.33 no.3
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    • pp.114-127
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    • 2012
  • Recent technical advancement allows noninvasive measurement of blood glucose. In this literature, we reviewed various noninvasive techniques for measuring glucose concentration. Optical or electrical methods have been investigated. Optical techniques include near-infrared spectroscopy, Raman spectroscopy, optical coherence technique, polarization, fluorescence, occlusion spectroscopy, and photoacoustic spectroscopy. Electrical methods include reverse iontophoresis, impedance spectroscopy, and electromagnetic sensing. Ultrasound, detection from breath, or fluid harvesting technique can be used to measure blood glucose level. Combination of various methods is also promising. Although there are many interesting and promising technologies and devices, there need further researches until a commercially available non-invasive glucometer is popular.

Effects of Peony-Licorice Mixture Supplementation on Blood Glucose and Lactate Levels (작약감초탕 섭취가 운동수행 후 혈당과 젖산의 변화에 미치는 영향)

  • Ha, Sung;Lee, Ho-Keun;Seo, Dong-Il
    • The Korea Journal of Herbology
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    • v.27 no.5
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    • pp.93-97
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    • 2012
  • Background : The purpose of this study was to examine that the effects of Peony-Licorice (PL) mixture supplementation on post-exercise blood glucose and lactate in professional women basketball players. Methods: Eleven professional women basketball players were participated in this study. The subjects participated in two trials, PL supplementation and water supplementation. They did 20-meter shuttle run test, and measured blood glucose and lactate level before, immediately, after 3 minutes, after 5 minutes and after 10 minutes the test. Results: There was not interaction effect on blood glucose(p<0.433) and lactate(p<0.770) levels. Blood glucose and lactate levels were increased in PL group and water group after the test. Conclusion: PL supplementation could not affect changing blood glucose and lactate level. Therefore, we suggest that PL supplementation may not be positive ergogenic aid for improving exercise performance in professional women basketball players.

Determination of Glucose Distribution of Potato Tuber Using Blood Glucose Meter and Its Application to Estimate Processing Quality (혈당측정기를 이용한 감자 괴경의 포도당 분포 분석과 이의 가공적성 평가에의 활용)

  • Kwon, Byoung-Hoon;Kim, Si Un;Lim, Soo Yeon;Namgung, Hyeju;Lee, Hong Jin
    • Horticultural Science & Technology
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    • v.32 no.2
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    • pp.171-177
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    • 2014
  • In an effort to investigate special distribution of glucose content of potato tuber of a cultivar 'Superior' after harvest, a whole tuber was longitudinally cut into halves and cut-surface was divided into 11 regions. Approximate glucose concentration of each section was determined using a commercial blood glucose meter. Higher level of glucose was detected in the outer layers of tissue than inner part of tuber although there were lower coefficients of variation value, 37.4% and 34.1% among individual tubers and among defined sections, respectively. A positive correlation between the whole tuber and individual section was existed in glucose content, where the central pith tissue gave the highest coefficient (r = 0.921) and bud end tissue did the lowest (r = 0.544). Glucose content of the tubers stored for 4 months at $2.0^{\circ}C$ was 5.5 fold higher compared to the tubers kept in ambient temperature. The chip color of the former tubers was much brighter than those of the latter tubers. The result obtained in the present study suggests that the blood glucose meter can be used to a rapid and simple evaluation of glucose content and therein be applied to estimate the processing quality of potato tubers during postharvest handling.

Analytical Evaluation of PPG Blood Glucose Monitoring System - researcher clinical trial (PPG 혈당 모니터링 시스템의 분석적 평가 - 연구자 임상)

  • Cheol-Gu Park;Sang-Ki Choi;Seong-Geun Jo;Kwon-Min Kim
    • Journal of Digital Convergence
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    • v.21 no.3
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    • pp.33-39
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    • 2023
  • This study is a performance evaluation of a blood sugar monitoring system that combines a PPG sensor, which is an evaluation device for blood glucose monitoring, and a DNN algorithm when monitoring capillary blood glucose. The study is a researcher-led clinical trial conducted on participants from September 2023 to November 2023. PPG-BGMS compared predicted blood sugar levels for evaluation using 1-minute heart rate and heart rate variability information and the DNN prediction algorithm with capillary blood glucose levels measured with a blood glucose meter of the standard personal blood sugar management system. Of the 100 participants, 50 had type 2 diabetes (T2DM), and the average age was 67 years (range, 28 to 89 years). It was found that 100% of the predicted blood sugar level of PPG-BGMS was distributed in the A+B area of the Clarke error grid and Parker(Consensus) error grid. The MARD value of PPG-BGMS predicted blood glucose is 5.3 ± 4.0%. Consequentially, the non-blood-based PPG-BGMS was found to be non-inferior to the instantaneous blood sugar level of the clinical standard blood-based personal blood glucose measurement system.

Research on a Non-invasive Blood Glucose level Estimation Algorithm based on Near- infrared Spectroscopy (근적외선 분광법 기반 비침습식 혈당 수치 추정 알고리즘 연구)

  • Young-Man Kang;Soon-Hee Han
    • The Journal of the Korea institute of electronic communication sciences
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    • v.18 no.6
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    • pp.1353-1362
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    • 2023
  • Various methods are being attempted to resolve the inconvenience of blood glucose meters used to check blood sugar levels. In this paper, we attempted to estimate blood sugar levels non-invasively using machine learning technology from spectral data acquired using a near-infrared sensor. The non-invasive blood glucose meter used in the study has a total of six near-infrared ray emitters, including visible rays, and a light receiver that receives them. It is a device created to collect spectral data on specific parts of the human body, such as the fingers. To verify whether there was a significant difference depending on blood sugar level, we attempted to estimate blood sugar level through machine learning algorithms. As a result of applying five machine learning algorithm techniques to the collected data and adjusting various hyper parameters, it was confirmed that the support vector regression algorithm showed the best performance.

Present Status and Analysis for IEEE 11073 Personal Health Device Specializations (IEEE 11073 개인건강기기별 표준 현황 및 분석)

  • Park, Han-Na;Kim, Seung-Hwan;Yoo, Done-Sik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.6C
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    • pp.469-475
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    • 2012
  • Increasing interest of life expectancy and health has made the u-health industry activating and the several international standard developing organizations(SDO) are dealing with u-health services and technologies. Among them, IEEE 11073 PHD(Personal Health Devices) Work Group is developing standards of personal health device communication for interoperability. There are many studies for introducing SDOs and analyzing the IEEE 11073-20601 standard. However, due to the rare study of PHD standards analysis, there are a lot of difficulties to utilize the standards. In this paper, present status of national and international SDOs including IEEE 11073 standards for PHD will be introduced. Moreover, device specialization standards such as thermometer, weighing scale, glucose meter, blood pressure monitor, electrocardiograph (ECG) etc.. will be analyzed based on the IEEE 11073-20601.

Risk Factors in Relation to Blood Pressure in Schoolchildren (국민학교 학동의 혈압에 관련된 요인분석)

  • Lee, Dong-Soo;Lee, Kyeong-Soo;Kang, Pock-Soo
    • Journal of Yeungnam Medical Science
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    • v.10 no.2
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    • pp.345-359
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    • 1993
  • This study was conducted to identify the factors related to the blood pressure in school children. The study subjects were 144 boys and 140 girls aged 10 years old, 4th grade student of one elementary school in Taegu City. Blood pressure and 18 variables for 284 school children were measured in May 1992. A weight-for-height index, R$\ddot{o}$hrer index(weight/$height^3$) was calculated for each individual as a measure of obesity. Body fat percent, fat weight, and lean body mass were measured by impedance fat meter(Model SIF-891). Serum total cholesterol, high-density lipoprotein, triglyceride, uric acid, total protein, and electrolyte were measured by automated clinical chemistry analyzer(Hitachi 4020). Low-density lipoprotein and atherogenic index were calculated by the equation. The variables assessed were sex, systolic blood pressure, diastolic blood pressure. R$\ddot{o}$hrer index, body fat percent, body fat weight, lean body mass, total cholesterol, high-density lipoprotein, low-density lipoprotein, uric acid, total protein, serum electrolyte and blood glucose. The mean systolic and diastolic blood pressures for boys were 104.1mmHg and 66.6mmHg and those for girls were 102.9mmHg and 67.5mmHg. Systolic blood pressure of boys was positively correlated with height, weight, R$\ddot{o}$hrer index, fat weight, lean body mass, and triglyceride. Systolic blood pressure of girls was positively correlated with height, weight, lean body mass, and uric acid. Diastolic blood pressure of boys was positively correlated with weight. R$\ddot{o}$hrer index, and lean body mass. Diastolic blood pressure of girls was positively correlated with height, weight, fat weight, and lean body mass and negatively with total serum protein. In multiple regression analysis for the systolic blood pressure, the significant independent variables were R$\ddot{o}$hrer index and serum sodium in boys, and serum uric acid, fat percent, and R$\ddot{o}$hrer index in girls. In multiple regression analysis of the diastolic blood pressure, the significant independent variables were R$\ddot{o}$hrer index in boys and total serum protein in girls. This study indicated that important factors influencing blood pressure in school children were R$\ddot{o}$hrer index, fat percent, serum sodium, uric acid, and total protein. R$\ddot{o}$hrer index was most important among these. It is recommended to enforce the nutritional education for diet control of obesity to prevent hypertention in children and to adopt healthy life-styles that promote good health and prevent development of cardiovascular risk factors.

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