• Title/Summary/Keyword: Calibration verification

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An Empirical Validation Study for Calibration Verification in TDM Test (검량보정 검증의 실험적 적합성에 대한 연구 -치료적 약물검사를 중심으로-)

  • Chang, Sang-Wu;Kim, Nam-Yong;Choi, Ho-Sung;Park, Yong-Won;Chu, Gyung-Bok;Yun, Keun-Young;Park, Byung-Ok
    • Korean Journal of Clinical Laboratory Science
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    • v.37 no.1
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    • pp.1-7
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    • 2005
  • The purpose of this study was to verify (i) a consistent calibration verification for the assessment of method linearity and (ii) calibration agreement with calibration settings. We validated calibration verification through method linearity with different lot number of individual calibrators that span the working range for 9 tests except salicylate with control sample in test. We evaluated that it covered broad analyte range to assay from near zero to the top of the measuring range with 5 or 6 points every three times for 10 analytes in TDM test. Target values were plotted on X-axis with assigned or observed values on the Y-axis. Working range were as follows. Calibration verification of the measuring range (maximum to minimum values) has been validated asetaminophen 0.1 to $304.6_{\mu}g/mL$, salicylate 0 to $1005_{\mu}g/mL$, valproic acid 3.2 to $154.19_{\mu}g/mL$, digoxin 0.17 to 5.65 ng/mL, vancomycine 1.3 to $80.51_{\mu}g/mL$, carbarmazepine 0.1 to $22.3_{\mu}g/mL$, phenytonin 0.6 to $40.21_{\mu}g/mL$, theophyline 0.2 to $40.21_{\mu}g/mL$, primidone 0 to $24.07_{\mu}g/mL$, phenobarbital 0.6 to $60.0_{\mu}g/mL$. Drawing a straight line through five or six points of these data showed good linearity. We are sure that it is important to assess the calibration verification of a test method to ascertain the lowest and highest test results that are reliable.

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Calibration and Verification of a Tidal Prism Eutrophication Model for the Lynnhaven Bay (U.S.A)

  • PARK Kyeong;KUO Albert Y.
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.30 no.6
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    • pp.964-973
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    • 1997
  • A tidal prism eutrophication model, an one-dimensional intertidal model, is developed to study water quality conditions at small coastal basins and tidal creeks. The model simulates the physical transport processes using the concept of tidal flushing. The concept is simple and straightforward, and thus is ideal for small coastal basins with complex geometry. The model, having twenty-four state variables in the water column, simulates salinity, temperature, dissolved oxygen, three algal groups, and the cycles of carbon, nitrogen, phosphorus and silica. The model is applied to the Lynnhaven Bay, a small coastal basin of Chesapeake Bay in U.S.A. The model is calibrated using the field data collected in 1994, and then is verified using the independently collected data in 1980. The model overall gives a good reproduction of the field data, partly owing to the data collected from the field surveys specifically designed for the model application. This paper presents the procedure, and the results of the model calibration and verification.

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Calibration and Verification of a Hydrodynamic Model in Chunsu Bay and Adjacent Coastal Water (천수만과 인근연안에서 수역학모델의 보정 및 검증)

  • Kyeong Park;Jeong Hwan Oh
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.10 no.3
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    • pp.109-119
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    • 1998
  • A horizontal tow-dimensional version of POM (Princeton Ocean Model) was modified in representing the bottom friction and the open boundary conditions. To simulate the flooding and drying of intertidal flats, a wetting-and-drying scheme was incorporated into the model. The model then was applied to the Chunsu Bay and its adjacent coastal water. Only the water movement due to tides, the dominant forcing in the study area, was considered. This presents the procedure and the results of model calibration and verification for the Chunsu Bay system. The model was calibrated, using the average tidal characteristics in Tide Tables, for the amplitudes and the phases of tidal waves throughout the modeling domain. Calibration results showed that the model gave a good reproduction of tidal waves. The calibrated model was verified using the time-series measurements of surface elevation and current velocity in the summer of 1995. The model reproduced the tides currents very well. calibration and verification results demonstrated that the model is capable of reproducing the tidal dynamics in the Chunsu Bay system.

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Study of statistical distribution for four-port TEM cell

  • Jeon, Sangbong;Kwon, Jong-Hwa
    • Journal of Multimedia Information System
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    • v.1 no.2
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    • pp.127-132
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    • 2014
  • The transverse electromagnetic (TEM) cells are widely used for electromagnetic compatibility (EMC) testing and field probe calibrations. We propose the verification of TEM mode with statistical method using a four-port TEM cell. The verification results are compared with Normal, Rayleigh, and Gamma distribution. As a result, the 75 % quantile of the Rayleigh distribution is excellent agreement with the true quantiles for a number of calibration points.

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Analysis of Calibration Facilities for Acoustic Doppler Current Profilers (ADCPs) (초음파 도플러 유속계 교정 시설 현황)

  • Lee, Jung-Han;Hwang, Keun-Choon;Kim, Eun-Soo
    • Ocean and Polar Research
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    • v.33 no.2
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    • pp.171-183
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    • 2011
  • Despite technological developments and application advances of Acoustic Doppler Current Profilers (ADCPs), no standard procedure has been adopted or accepted for calibration of ADCPs. Limitations of existing facilities for calibrating ADCPs, the complexity of ADCP instruments, and rapid changes in ADCP technology are some of the reasons why a standard procedure has not been adopted. However, there is increasing realization of the need for effective Quality Assurance (QA) and as part of that the importance of standardized calibration. In this study, the significance of calibration and QA plans for ADCPs is discussed and the calibration facilities for ADCPs at home and abroad are reported. Furthermore, the method for calibrating ADCPs using a towed car and its limitations are discussed. This study contributes to discussions surrounding the establishment of standard procedures for calibrating ADCPs and QA plans, and the construction of calibration facilities in the future.

Simulation of the Reduction Effect of Soil Loss Using SWAT Model (SWAT 모형을 이용한 토양유실량 저감효과 모의)

  • Jeong, Jin-Kweon;Kim, Hwan-Gi
    • Journal of Environmental Impact Assessment
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    • v.17 no.4
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    • pp.243-253
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    • 2008
  • The purpose of this study was to simulate the reduction effect of soil loss in the Yongdam reservoir watershed using SWAT model. To evaluate accuracy for flow and sediment yield of SWAT model, calibration was performed for the period from Jan. 2002 to Dec. 2003, and the verification for Jan. 2005 to Dec. 2005. The calibration and the verification were carried out using data observed at the Cheoncheon gaging station. The $R^2$ and EI values in terms of a flow were 0.8 and 0.78 respectively for calibration, whereas they for verification were 0.88 and 0.86 respectively. In terms of a sediment yield, they were 0.7 and 0.48 respectively for calibration, whereas for verification were 0.64 and 0.54 respectively. As a results from model simulation, annual mean soil loss rates in terms of forest, paddy and upland were 0.02 ton/ha/yr, 0.15 ton/ha/yr and 7.58 ton/ha/yr, respectively. The results show that the land use type of a upland has more significant impact on a total soil loss as well as a sediment yield than other types of land use. The sediment delivery ratio was determined to be about 0.35. In this study 2 land cover change scenarios for upland area were considered. These scenarios were used an input to SWAT model in order to evaluate their impact on soil loss and sediment delivery. The results show that a reduction of the upland area would reduce the soil loss and sediment yield.

Development of a Hybrid Watershed Model STREAM: Test Application of the Model (복합형 유역모델 STREAM의 개발(II): 모델의 시험 적용)

  • Cho, Hong-Lae;Jeong, Euisang;Koo, Bhon Kyoung
    • Journal of Korean Society on Water Environment
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    • v.31 no.5
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    • pp.507-522
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    • 2015
  • In this study, some of the model verification results of STREAM (Spatio-Temporal River-basin Ecohydrology Analysis Model), a newly-developed hybrid watershed model, are presented for the runoff processes of nonpoint source pollution. For verification study of STREAM, the model was applied to a test watershed and a sensitivity analysis was also carried out for selected parameters. STREAM was applied to the Mankyung River Watershed to review the applicability of the model in the course of model calibration and validation against the stream flow discharge, suspended sediment discharge and some water quality items (TOC, TN, TP) measured at the watershed outlet. The model setup, simulation and data I/O modules worked as designed and both of the calibration and validation results showed good agreement between the simulated and the measured data sets: NSE over 0.7 and $R^2$ greater than 0.8. The simulation results also include the spatial distribution of runoff processes and watershed mass balance at the watershed scale. Additionally, the irrigation process of the model was examined in detail at reservoirs and paddy fields.

Uncertainty Assessment: Relative versus Absolute Point Dose Measurement for Patient Specific Quality Assurance in EBRT

  • Mahmood, Talat;Ibrahim, Mounir;Aqeel, Muhammad
    • Progress in Medical Physics
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    • v.28 no.3
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    • pp.111-121
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    • 2017
  • Verification of dose distribution is an essential part of ensuring the treatment planning system's (TPS) calculated dose will achieve the desired outcome in radiation therapy. Each measurement have uncertainty associated with it. It is desirable to reduce the measurement uncertainty. A best approach is to reduce the uncertainty associated with each step of the process to keep the total uncertainty under acceptable limits. Point dose patient specific quality assurance (QA) is recommended by American Association of Medical Physicists (AAPM) and European Society for Radiotherapy and Oncology (ESTRO) for all the complex radiation therapy treatment techniques. Relative and absolute point dose measurement methods are used to verify the TPS computed dose. Relative and absolute point dose measurement techniques have a number of steps to measure the point dose which includes chamber cross calibration, electrometer reading, chamber calibration coefficient, beam quality correction factor, reference conditions, influences quantities, machine stability, nominal calibration factor (for relative method) and absolute dose calibration of machine. Keeping these parameters in mind, the estimated relative percentage uncertainty associated with the absolute point dose measurement is 2.1% (k=1). On the other hand, the relative percentage uncertainty associated with the relative point dose verification method is estimated to 1.0% (k=1). To compare both point dose measurement methods, 13 head and neck (H&N) IMRT patients were selected. A point dose for each patient was measured with both methods. The average percentage difference between TPS computed dose and measured absolute relative point dose was 1.4% and 1% respectively. The results of this comparative study show that while choosing the relative or absolute point dose measurement technique, both techniques can produce similar results for H&N IMRT treatment plans. There is no statistically significant difference between both point dose verification methods based upon the t-test for comparing two means.

Development of Easy Measurement Method of Orthogonal Triple-Sensor Hot-Wire Anemometer (삼직교 열선유속계의 간편한 측정법 개발)

  • Kim, Jin-Kwon;Kang, Shin-Hyoung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.1
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    • pp.85-92
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    • 2000
  • Easy measurement method of orthogonal triple-sensor hot-wire anemometer is developed. Advantages of the new method is that it does not require either the exact orthogonality of the installed wires which cannot be kept during the probe manufacture and repair, nor the knowledge of the wire installation angles and the yaw and pitch coefficient of the wires. The new method introduced yaw and pitch calibration coefficients which are designed to increase monotonically with yaw and pitch angles. So the resulting calibration network is simple to recognize compared with that of the previously suggested calibration method. Verification experiments showed good accuracy and independency of the directional calibration on velocity.

Auto Calibration of Water Quality Modeling Using NGIS (NGIS자료와 연계한 수질모의 결과의 자동보정)

  • Han, Kun Yeun;Lee, Chang Hee;Kim, Kang Mo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2004.05b
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    • pp.1400-1403
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    • 2004
  • The current industrial development and the Increase of population along Nakdong River have produced a rapid Increase of wastewater discharge. This has resulted in problem of water quality control and management. Although many efforts have been carried out, water quality has not significantly improved. The goal of this study is to design a NGIS-based water quality management system for the scientific water quality control and management in the Nakdong River. For general water quality analysis, QULA2E model was applied to the Nakdong River. A sensitivity analysis was made to determine significant parameters and an optimization was made to estimate optimal values. The calibration and verification were performed by using observed water quality data for Nakdong River. A water qualify management system for Nakdong River was made by connecting the QUAL2E model to ArcView. It allows a Windows-based Graphic User Interface(GUI) to implement all operation with regard to water quality analysis. The modeling system in this study will be an efficient NGIS for planning of water quality management.

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