• Title/Summary/Keyword: Characterization

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Characterization of Test Substance in the GLP (GLP 시험에서의 시험물질 특성파악)

  • Lee, Eun-Jung;Song, Kyung-Seuk;Yu, Il-Je
    • Toxicological Research
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    • v.23 no.2
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    • pp.173-177
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    • 2007
  • The GLP contains specific language concerning characterization of the test, control and reference substances used in toxicity studies. This paper will describe and discuss what types of documents are required to support test/reference substance characterization under GLP system. The purpose of this article is to present an overview of data needed in the characterization package that will adequately define the substance. Most sponsors use a certificate of analysis (COA) to communicate the test sub-stance characterization status information to the contracting research organizations. The COA should provide the test $material^{\circ}{\phi}s$ characterization results, substance storage requirements, expiration dates, verification of the collection of the retention sample, archival location of the data to support the characterization and GLP compliance status of the characterization.

Influence of Silicon and Seed Particles on the Reconstruction Characteristics and Exaggerated Grain Growth of MgO Protective Layer by Over-Frequency Accelerated Discharge in ACPDPs

  • Kwon, Sang-Koo;Kim, Jeong-Ho;Moon, Seung-Kyu;Choi, Jong-Kwon;Park, Kyu-Ho;Han, Sung-Su
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.957-960
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    • 2008
  • The influences of silicon and MgO seed particle on the reconstruction characteristics of MgO protective layer were investigated to clarify the mechanism of reconstruction and exaggerated grain growth (EGG) in AC-PDP. The reconstruction and EGG are closely correlated with the driving force for nucleation and growth, interface energy and initial size distribution of MgO protective layer in plasma space during discharge in AC-PDP.

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Electrochemistry Characterization of Nickel Using Ethanolamine Compound Additives (에탄올아민화합물 첨가에 대한 니켈의 전기화학적 특성)

  • Park, Keun-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.4
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    • pp.531-538
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    • 2010
  • The electrochemistry characterization of metal is important in many industrial applications. In this study, we investigated the C-V diagrams related to the electrochemistry characterization of nickel. We determined electrochemical measurement by using cyclic voltammetry with a three electrode system. A measuring range was reduced from initial potential to -1350mV, continuously oxidized to 1650mV and measured to the initial point. The scan rate were 100, 150, 200 and 200mV/s. As a result, the C-V characterization of nickel using ethanolamine and ethylethanolamine inhibitor appeared irreversible process caused by the oxidation current from the cyclic voltammogram. After adding ethanolamine compound additive, adsorption film constituted, and the passive phenomena happened. According to the results by cyclic voltammetry method, it was revealed that the effect of the electrochemistry characterization of nickel depends on ethanolamine structure interaction to adsorption complex.

Virtual Experimental Characterization of 3D Orthogonal Woven Composite Materials (직교 직물 복합재료 물성치 예측을 위한 가상 수치 실험)

  • Lee, Chang-Sung;Shin, Hun;Kim, Seung-Jo
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2001.05a
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    • pp.205-210
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    • 2001
  • In this work, virtual material characterization of 3D orthogonal woven composites is performed to predict the elastic properties by a full scale FEA. To model the complex geometry of 3D orthogonal woven composites, an accurate unit structure is first prepared. The unit structure includes warp yarns, filler yarns, stuffer yams and resin regions and reveals the geometrical characteristics. For this virtual experiments by using finite element analysis, parallel multifrontal solver is utilized and the computed elastic properties are compared to available experimental results and the other analytical results. It is founded that a good agreement between material properties obtained from virtual characterization and experimental results. Using the method of this virtual material characterization, the effects of inconsistent filler yarn distribution on the in-plane shear modulus and filler yarn waviness on the transverse Young's modulus are investigated. Especially, the stiffness knockdown of 3D woven composite structures is simulated by virtual characterization. Considering these results, the virtual material characterization of composite materials can be used for designing the 3D complex composite structures and may supplement the actual experiments.

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Review of Site Characterization Methodology for Deep Geological Disposal of Radioactive Waste (방사성폐기물의 심층 처분을 위한 부지특성조사 방법론 해외 사례 연구)

  • Park, Kyung-Woo;Kim, Kyung-Su;Koh, Yong-Kwon;Jo, Yeonguk;Ji, Sung-Hoon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.15 no.3
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    • pp.239-256
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    • 2017
  • In the process of site selection for a radioactive waste disposal, site characterization must be carried out to obtain input parameters to assess the safety and feasibility of deep geological repository. In this paper, methodologies of site characterization for radioactive waste disposal in Korea were suggested based on foreign cases of site characterization. The IAEA recommends that site characterization for radioactive waste disposal should be performed through stepwise processes, in which the site characterization period is divided into preliminary and detailed stages, in sequence. This methodology was followed by several foreign countries for their geological disposal programs. General properties related to geological environments were obtained at the preliminary site characterization stage; more detailed site characteristics were investigated during the detailed site characterization stage. The results of investigation of geology, hydro-geology, geochemistry, rock mechanics, solute transport and thermal properties at a site have to be combined and constructed in the form of a site descriptive model. Based on this site descriptive model, the site characteristics can be evaluated to assess suitability of site for radioactive waste disposal. According to foreign site characterization cases, 7 or 8 years are expected to be needed for site characterization; however, the time required may increase if the no proper national strategy is provided.