• Title/Summary/Keyword: Charged particle therapy

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A Scheduling System for the Patient Treatment on a Heavy-ion Radiotherapy

  • Toyama, Hinako;Shibayama, Kouichi;Kanatsu, Syusuke;Kuroiwa, Toshitaka;Watanabe, Hideo;Wakaisami, Mitsuji;Tsuji, Hiroshi;Endo, Masahiro;Tsujii, Hirohiko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.177-179
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    • 2002
  • We have developed a scheduling system for heavy ion radiotherapy considering the condition of three treatment rooms and treatment planning for each patient. This system consists of a database (patient information, treatment method and machine schedule), a schedule for radiotherapy and WEB server. All operation of this system, such as data input, to change and to view the schedule, are performed by using a WEB browser. In order to protect personal information for the patients, access privilege to each information are limited by according to the occupational category. This system is connected with a hospital central information management system (AMIDAS) and an irradiation-managing computer for the heavy ion radiotherapy. A basic information for the patient is got from AMIDAS and the daily schedule sends to the treatment control computer at each treatment room through the irradiation-managing computer every morning. The daily, weekly, monthly schedules in the treatment room and the treatment condition of each patient are shared on the WEB browser with the all participants of the heavy ion therapy. This system could be useful to save a time to generate a treatment schedule and to inform us the most up-to-date treatment schedule and the related information at the same time.

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Profile and Dose Distribution for Therapeutic Heavy Ion Beams

  • Sasaki, Hitomi;Komori, Masataka;Kohno, Toshiyuki;Kanai, Tatsuaki;Hirai, Masaaki;Urakabe, Eriko;Nishio, Teiji
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.211-213
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    • 2002
  • The purpose of this work is acquiring some parameters of therapeutic heavy ion beams after penetrating a thick target. The experiments were performed using a pencil-like $\^$12/C beam of about 3 mm in diameter from NIRS-HIMAC, and the data were taken at several points of the target thickness for $\^$12/C beam of 290 MeV/u and 400 MeV/u. By the simultaneous measurements using some detectors, the atomic number of each fragment particle was identified, and the beam profile, the dose distribution and the LET spectrum for each element were derived.

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An Analysis on Treatment Schedule of Carbon Ion Therapy to Early Stage Lung Cancer

  • Sakata, Suoh;Miyamoto, Tadaaki;Tujii, Hirohiko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.174-176
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    • 2002
  • A total of 134 patients with stage 1 of non-small cell lung cancer treated by carbon ion beam of HIMAC NIRS were investigated for control rate and delivered dose. The delivered dose of every patient was converted to biological effective dose (BED) of LQ model using fraction number, dose per fraction and alpha beta ratio which shows the maximum correlation between BED and tumor control. The BED of every patient was classified to establish a BED response curve for control. Assuming fraction numbers, dose response curves were introduced from BED response curve. The total doses to realize several control rates were obtained for the treatment of small fraction number.

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Basics of particle therapy I: physics

  • Park, Seo-Hyun;Kang, Jin-Oh
    • Radiation Oncology Journal
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    • v.29 no.3
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    • pp.135-146
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    • 2011
  • With the advance of modern radiation therapy technique, radiation dose conformation and dose distribution have improved dramatically. However, the progress does not completely fulfi ll the goal of cancer treatment such as improved local control or survival. The discordances with the clinical results are from the biophysical nature of photon, which is the main source of radiation therapy in current field, with the lower linear energy transfer to the target. As part of a natural progression, there recently has been a resurgence of interest in particle therapy, specifically using heavy charged particles, because these kinds of radiations serve theoretical advantages in both biological and physical aspects. The Korean government is to set up a heavy charged particle facility in Korea Institute of Radiological & Medical Sciences. This review introduces some of the elementary physics of the various particles for the sake of Korean radiation oncologists' interest.

Proton Beam Dosimetry Intercomparison

  • Fukumura, Akifumi;Kanai, Tatsuaki;Kanematsu, Nobuyuki;Yusa, Ken;Maruhashi, Akira;Nohtomi, Akihiro;Nishio, Teiji;Shimbo, Munefumi;Akagi, Takashi;Yanou, Toshihiro;Fukuda, Shigekazu;Hasegawa, Takashi;Kusano, Yohsuke;Masuda, Yasutaka
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.252-254
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    • 2002
  • A new protocol for dosimetry in external beam radiotherapy is published by the Japan Society of Medical Physics (JSMP) in 2002. The protocol deals with proton and heavy ion beams as well as photon and electron beams, in accordance with IAEA Technical Report Series No. 398. To establish inter-institutional uniformity in proton beam dosimetry, an intercomparison program was carried out with the new protocol. The absorbed doses are measured with different cylindrical ionization chambers in a water phantom at a position of 30-mm residual range for a proton beam, that had range of 155 mm and a spread out Bragg peak (SOBP) of 60-mm width. As a result, the intercomparison showed that the use of the new protocol would improve the +/- 1.0 % (one standard deviation) and 2.7 % (maximum discrepancy) differences in absorbed doses stated by the participating institutions to +/- 0.3% and 0.9 %, respectively. The new protocol will be adopted by all of the participants.

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Theoretical Background on Heavy Charged Particle Therapy and Proton Monte Carlo Simulation (중하전입자 치료의 이론적 배경과 양성자에 대한 몬테칼로 시뮬레이션)

  • 이정옥;이상공;김종일;정동혁;문성록;강정구
    • Progress in Medical Physics
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    • v.8 no.1
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    • pp.47-52
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    • 1997
  • Simulations were performed using a Monte Carlo technique in order to show physical phenomena occurring when a heavy charged particle such as proton or alpha particle traverses the medium. It was confirmed that the sharp Bragg peak occurred deeper in the water with the increasing proton energy. It is found that the use of such a sharp Bragg peak due to heavy charged particles would be far superior to the case of the photon or electron, since the absorbed dose in the target tissues would be better localized, thereby minimizing the damage to the surrounding tissues.

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Precise Measurement of Beam Energy and Range with TOF and Counter Telescope System

  • Nanbu, Shuya;Kanai, Tatsuaki;Kohno, Toshiyuki;Ohno, Yumiko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.225-227
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    • 2002
  • In order to improve the accuracy of charged-particle radiation therapy, the beam energy was measured precisely using a TOF-system, and the range using a counter telescope system. A Si detector and a Ge detector were used to estimate the range straggling as a $\Delta$E and an E detector, respectively, because they have good energy resolution and the output pulse heights don't depend on the atomic number of detected particles. The results were compared with the theoretical values by a calculation code.

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Feasibility study of using triple-energy CT images for improving stopping power estimation

  • Yejin Kim;Jin Sung Kim ;Seungryong Cho
    • Nuclear Engineering and Technology
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    • v.55 no.4
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    • pp.1342-1349
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    • 2023
  • The planning accuracy of charged particle therapy (CPT) is subject to the accuracy of stopping power (SP) estimation. In this study, we propose a method of deriving a pseudo-triple-energy CT (pTECT) that can be achievable in the existing dual-energy CT (DECT) systems for better SP estimation. In order to remove the direct effect of errors in CT values, relative CT values according to three scanning voltage settings were used. CT values of each tissue substitute phantom were measured to show the non-linearity of the values thereby suggesting the absolute difference and ratio of CT values as parameters for SP estimation. Electron density, effective atomic number (EAN), mean excitation energy and SP were calculated based on these parameters. Two of conventional methods were implemented and compared to the proposed pTECT method in terms of residuals, absolute error and root-mean-square-error (RMSE). The proposed method outperformed the comparison methods in every evaluation metrics. Especially, the estimation error for EAN and mean excitation using pTECT were converging to zero. In this proof-of-concept study, we showed the feasibility of using three CT values for accurate SP estimation. Our suggested pTECT method indicates potential clinical utility of spectral CT imaging for CPT planning.