• Bulletin of the Korean Chemical Society
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• v.25 no.6
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• pp.927-930
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• 2004

• Advances in nano research
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• v.10 no.1
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• pp.71-76
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• 2021

Synthesis of nanoparticles using green technology using plants is gaining significant attention as it is an environmentally friendly substitute to conventional physical and chemical methods. The present study was focused on the chemical and green synthesis of Iron Oxide nanoparticles from ferric chloride. The green synthesis was achieved by utilizing the bio components of Hibiscus rosa-sinensis. The Fe3O4 nanoparticles with the size range of 87-400 nm were synthesized by wet chemical reduction technique which are unstable, prone to aggregation while in green synthesis the phytochemicals present in the leaf extract acts as the capping as well as the reducing agent thus the green synthesized iron (III) oxide nanoparticles were naturally stabilized, spherical shaped and are in the size range of 2-80 nm. The results of both the protocols are compared and presented briefly.

• Bulletin of the Korean Chemical Society
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• v.32 no.8
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• pp.2776-2778
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• 2011

• Bulletin of the Korean Chemical Society
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• v.26 no.11
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• pp.1803-1806
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• 2005

Formation of octahedral shaped PbSe quantum dots at higher synthesis temperature is being reported in this paper. The synthesis includes the reaction between lead oleate and trioctylphosphine selenide under inert gas conditions to produce PbSe. TEM, SEM, XRD and EDS were used to characterize the samples. The SEM exhibited the formation of spherical shaped nanocrystals at temperature below 140 ${^{\circ}C}$ and octahedral shaped nanoparticles at higher temperatures. Moreover, the TEM also showed the well resolved (111) lattice fringes proving that the nanocrystals were crystalline in nature. Synthesis of highly pure PbSe nanocrystals was another interesting aspect of this research.

• Bulletin of the Korean Chemical Society
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• v.30 no.6
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• pp.1325-1330
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• 2009

A general method has been developed for the solid phase synthesis of drug-like 7-aryl-benzo[b][1,4]oxazin-3(4H)- one derivatives 6. The method relies on a novel, microwave irradiation promoted cyclization reaction of the BOMBA resin bound, N-substituted-$\alpha$-(2-chloro-4-bromophenoxy)acetamide 3 that takes place via a Smiles rearrangement. The 7-bromobenzo[1,4]oxazine 4, produced in this process is converted to 7-aryloxazin analogs 5 by utilizing Suzuki coupling with various substituted arylboronic acids. Finally, the target 7-aryl-benzo[b][1,4]oxazin-3(4H)-ones 6 are liberated from the resin by treatment with 5% TFA. The progress of the reactions involved in this preparative route can be monitored by using ATR-FTIR spectroscopy on a single bead. The target compounds, obtained by using this five-step sequence, are produced in high yields and purities.

• Bulletin of the Korean Chemical Society
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• v.27 no.5
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• pp.769-772
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• 2006

• Proceedings of the PSK Conference
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• 2003.10a
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• pp.89-89
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• 2003

Numerous lead compounds, based on multipurpose privileged structures, can be generated that address a variety of targets from a gene family of interest, irrespective of therapeutic area. Solid-phase organic synthesis has been emerged as a powerful technique in generating combinatorial libraries of small organic molecules useful for drug discovery. Heterocyclic compounds provide scaffolds on which pharmacophores can be arranged to yield potent and selective drugs and a variety of heterocycles have been synthesized on solid support. (omitted)

• Bulletin of the Korean Chemical Society
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• v.29 no.2
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• pp.313-318
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• 2008

An enantioselective ring opening of racemic terminal epoxides has been achieved by using heterobimetallic cobalt salen complexes with variety of nucleophiles. They were proven to be highly enantioselective and reactive for the synthesis of valuable chiral building blocks in enantio-riched forms up to 98% ee.

• Bulletin of the Korean Chemical Society
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• v.30 no.12
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• pp.3085-3088
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• 2009

• BMB Reports
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• v.38 no.5
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• pp.517-525
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• 2005

Solid phase peptide synthesis method, which was introduced by Merrifield in 1963, has spawned the concept of combinatorial chemistry. In this review, we summarize the present technologies of solid phase peptide synthesis (SPPS) that are related to combinatorial chemistry. The conventional methods of peptide library synthesis on polymer support are parallel synthesis, split and mix synthesis and reagent mixture synthesis. Combining surface chemistry with the recent technology of microelectronic semiconductor fabrication system, the peptide microarray synthesis methods on a planar solid support are developed, which leads to spatially addressable peptide library. There are two kinds of peptide microarray synthesis methodologies: pre-synthesized peptide immobilization onto a glass or membrane substrate and in situ peptide synthesis by a photolithography or the SPOT method. This review also discusses the application of peptide libraries for high-throughput bioassays, for example, peptide ligand screening for antibody or cell signaling, enzyme substrate and inhibitor screening as well as other applications.