• Bulletin of the Korean Chemical Society
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• v.12 no.1
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• pp.4-7
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• 1991

• Bulletin of the Korean Chemical Society
• /
• v.8 no.2
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• pp.130-132
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• 1987

• Bulletin of the Korean Chemical Society
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• v.13 no.6
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• pp.695-699
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• 1992

• Bulletin of the Korean Chemical Society
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• v.13 no.4
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• pp.444-447
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• 1992

• Bulletin of the Korean Chemical Society
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• v.14 no.6
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• pp.661-663
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• 1993

• Journal of Applied Biological Chemistry
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• v.62 no.1
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• pp.109-109
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• 2019

• Bulletin of the Korean Chemical Society
• /
• v.13 no.4
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• pp.346-348
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• 1992

• Bulletin of the Korean Chemical Society
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• v.12 no.4
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• pp.360-361
• /
• 1991

• Bulletin of the Korean Chemical Society
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• v.32 no.11
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• pp.3928-3932
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• 2011

We synthesized peptide-resin conjugates (1 and 2) by immobilizing ${\beta}$-sheet antibacterial peptide and ${\alpha}$ helical antibacterial peptide on PEG-PS resin, respectively. Conjugate 1 showed considerable antibacterial activity in various conditions, whereas conjugate 2 did not exhibit antibacterial activity. The growths of various bacteria were inhibited by conjugate 1 even at lower concentrations than MIC. Conjugate 1 killed bacteria at MIC and had a potent synergistic effect with current antibacterial agents such as vancomycin and tetracycline, respectively. Overall results indicate that polymer surface modification using antibacterial ${\beta}$ sheet peptide is a powerful way to prevent microbial contamination on polymer surfaces.

• Bulletin of the Korean Chemical Society
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• v.32 no.4
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• pp.1407-1410
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• 2011