• Title/Summary/Keyword: Comparative Analysis

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Bridging Comparative Genomics and DNA Marker-aided Molecular Breeding

  • Choi, Hong-Kyu;Cook, Douglas R.
    • Korean Journal of Breeding Science
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    • v.43 no.2
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    • pp.103-114
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    • 2011
  • In recent years, genomic resources and information have accumulated at an ever increasing pace, in many plant species, through whole genome sequencing, large scale analysis of transcriptomes, DNA markers and functional studies of individual genes. Well-characterized species within key plant taxa, co-called "model systems", have played a pivotal role in nucleating the accumulation of genomic information and databases, thereby providing the basis for comparative genomic studies. In addition, recent advances to "Next Generation" sequencing technologies have propelled a new wave of genomics, enabling rapid, low cost analysis of numerous genomes, and the accumulation of genetic diversity data for large numbers of accessions within individual species. The resulting wealth of genomic information provides an opportunity to discern evolutionary processes that have impacted genome structure and the function of genes, using the tools of comparative analysis. Comparative genomics provides a platform to translate information from model species to crops, and to relate knowledge of genome function among crop species. Ultimately, the resulting knowledge will accelerate the development of more efficient breeding strategies through the identification of trait-associated orthologous genes and next generation functional gene-based markers.

Development of new agrochemicals by quantitative structure-activity relationship (QSAR) methodology. III. 3D QSAR methodologies and computer-assisted molecular design (CAMD) (정량적인 구조-활성상관 (QSAR) 기법에 의한 새로운 농약의 개발. III. 3D QSAR 기법들과 컴퓨터를 이용한 분자설계(CAMD))

  • Sung, Nack-Do
    • The Korean Journal of Pesticide Science
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    • v.7 no.1
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    • pp.1-11
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    • 2003
  • Acoording to improvement of HTOS (high throughput organic synthesis) and HTS (high throughput screening) technique, the CoMFA (comparative molecular field analysis), CoMSIA (comparative molecular similarity indeces analysis) and molecular HQSAR (hologram quantitative structure-activity relationship) analysis techniques as methodology of computer assisted molecular design (CAMD) were introduced generally and summarized for some application cases.

An Analysis on the Competitive Structure of Fishery Products Export & Import between Korea and Japan (한ㆍ일 수산물 수출입 경쟁구조 분석)

  • 최정윤;김정봉
    • The Journal of Fisheries Business Administration
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    • v.34 no.2
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    • pp.141-164
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    • 2003
  • This study analysis the market status and competitive structure of Korean fishery in Japan import market, and derive policy implications for seeking main causes. Specifically', trade state between Korea and Japan is discovered and theoretical model is also used to analysis competitiveness between two countries. And then real measuring methods of competitive index is Introduced, the status of Korean fishery products in Japan import market is analysed totally through the study of comparative predominance and export competition. The analysis is based on the statistical methods such as RCA, RMI, and CMS. In summary, first, Korean fishery products have the comparative predominance in Japan, China and Thailand, but they have the comparative inferiority in USA, considering research results. Second, competitiveness of fishery products between Korea and in Japan import market extreme, relatively, competitiveness of Korean fishery products for Thailand's fishery products is lowest. Third, Korean fishery products maintain unconstant pattern, but competitive inputs result in increasing export to Japan generally.

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Exploratory Autopsy on Digital Payment Models

  • Wang, Tao;Kim, Chang-Su;Kim, Ki-Su
    • 한국경영정보학회:학술대회논문집
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    • 2007.06a
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    • pp.646-651
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    • 2007
  • Secure digital payment is critical in the successful shaping of global digital business. Digital payments are increasingly being used as a substitute to traditional payments, contributing markedly to the efficiency of the economy. The focus of every digital business transaction is to minimize risks arising from transactions. It is essential to ensure the security of digital payment whether used in internal networks or over wireless Internet. This paper analyses secure digital payment methods from the viewpoint of systemic security and transaction security. According to comparative analysis of digital payment models, this paper proposes a comparative analysis framework to investigate and evaluate secure digital payment. In conclusion, the comparative analysis framework, comparison of digital payment models and mobile payment models proposes a useful academic and practical foundation to enhance the understanding of secure digital payment methods. It also provides academic background and practical guidelines for the development of secure digital payment systems.

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Molecular Docking, 3D QSAR and Designing of New Quinazolinone Analogues as DHFR Inhibitors

  • Yamini, L.;Kumari, K. Meena;Vijjulatha, M.
    • Bulletin of the Korean Chemical Society
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    • v.32 no.7
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    • pp.2433-2442
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    • 2011
  • The three dimensional quantitative structure activity relationship (3D QSAR) models were developed using Comparative molecular field analysis (CoMFA), comparative molecular similarity indices analysis (CoMSIA) and docking studies. The fit of Quinazolinone antifolates inside the active site of modeled bovine dihydrofolate reductase (DHFR) was assessed. Both ligand based (LB) and receptor based (RB) QSAR models were generated, these models showed good internal and external statistical reliability that is evident from the $q^2_{loo}$, $r^2_{ncv}$ and $r^2_{pred}$. The identified key features enabled us to design new Quinazolinone analogues as DHFR inhibitors. This study is a building bridge between docking studies of homology modeled bovine DHFR protein as well as ligand and target based 3D QSAR techniques of CoMFA and CoMSIA approaches.

Comparison of QSAR Methods (CoMFA, CoMSIA, HQSAR) of Anticancer 1-N-Substituted Imidazoquinoline-4,9-dione Derivatives

  • Suh, Myung-Eun;Park, So-Young;Lee, Hyun-Jung
    • Bulletin of the Korean Chemical Society
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    • v.23 no.3
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    • pp.417-422
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    • 2002
  • Comparison studies of the Quantitative Structure Activity Relationship (QSAR) methods with new imidazo-quinolinedione derivatives were conducted using Comparative Molecular Field Analysis (CoMFA), Comparative Molecular Similarity Indices Analysis (CoMSIA), and the Hologram Quantitative Structure Activity Relationship (HQSAR). When the CoMFA crossvalidation value, q2, was 0.625, the Pearson correlation coefficient, r2, was 0.973. In CoMSIA, q2 was 0.52 and r2 was 0.979. In the HQSAR, q2 was 0.501 and r2 was 0.924. The best result was obtained using the CoMSIA method according to a comparison of the calculated values with the real in vitro cytotoxic activities against human ovarian cancer cell lines.

International Comparative Study on Sports for All Policy Patterns (생활체육정책 유형에 관한 국가 간 비교연구)

  • Jo, Woog-Yeon
    • The Journal of the Korea Contents Association
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    • v.12 no.4
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    • pp.457-467
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    • 2012
  • The purpose of the study was to explore the general characteristics of sports for all through the patterns of sports for all policy and analysis of causal relation of the determinants. To achieve this goal, 26 countries among OECD 30 members which provide useful data sources were selected. The data were analyzed by Qualitative Comparative Analysis(QCA) with cluster analysis. GDP, leisure time, social expenditure, Gini's coefficient, poverty rate and tax burden ratio were used as casual variables for Qualitative Comparative Analysis. The findings of this study were as follows. First, three patterns were examined and Korea was classified into the pattern which has low sports for all participation and sportsclub participation. Second, as a result of Qualitative Comparative Analysis for analyzing the determinants of sports for all patterns, the pattern in which includes Korea showed that GDP, leisure time, social expenditure, tax burden ratio had negative relationship and Gini's coefficient, poverty rate had positive relationship.

Comparative Education and Educational Evaluation (비교교육학과 교육평가학)

  • Park, Chanho
    • Korean Journal of Comparative Education
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    • v.28 no.1
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    • pp.135-151
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    • 2018
  • This study was conducted to help establish the status of comparative education as an academic discipline by investigating its relationship with educational evaluation. Comparative education as a subfield of education covers other areas of study in education, while educational evaluation is a study of methodology. First, international comparative study was investigated, and recent methodologies in educational evaluation were introduced. International comparative study started in 1960's, and is being expanded. The participating countries hope for better education by comparing their educational curricula and practices with others. For international comparative studies, a differential item functioning analysis as a multigroup analysis can provide information on what sociocultural factors other than the construct are affecting the measurement results. The study dataset has a hierarchical structure so that multilevel item response theory is suitable to obtain multidimensional national profiles. Although there have been methodological advances in educational evaluation, the methods are not available in comparative education. In order to reduce the gap, scholars in educational evaluation should try to make the methods easily available, while those in comparative education should try to use the exact and precise methods in their studies.

A Study on the Comparative Analysis of Brassiere Pattern between Girl Students and Adults (청소년 여학생(靑少年 女學生)과 성인 여성(成人 女性)의 브래지어 패턴 비교연구(比較硏究))

  • Sohn, Hee-Soon;Cha, Su-Joung
    • Journal of Fashion Business
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    • v.10 no.4
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    • pp.95-113
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    • 2006
  • This study was conducted comparative analysis of juvenile brassiere and adult brassiere to identify the problems of brassieres on the market. The raw data for this study was processed by SPSS 10.1 version(statistical software) and the results of this study can be summarized as follows. 1) The result of comparative analysis of juvenile brassiere and adult brassiere pattern is that each pattern showed no difference. 2) The results of the comparative analysis of juvenile and adult brassiere pattern in wing's length and angle is that even though there are some difference between juvenile and adult in side line inclination of brassiere. there is no setting difference but size of that brassiere. 3) The result of a comparative analysis pattern and cup size measurement of juvenile brassiere and adult brassiere is that even though the adult cup girth and angle is bigger than the juvenile because adults have more protrusive and bigger volume and well developed breast, some case rather the adult's cup angle is smaller than the juvenile as brand. And as we grow up to be a woman, difference of lower breast girth and breast girth are become big while difference of upper breast girth and breast girth are become small for that reason upper cup must be lower and lower cup must be higher but there is almost no difference between adult and juvenile. 4) The result of a comparative analysis of juvenile brassiere and adult brassiere bust point of the pattern is that adult brassiere's distance between bust points 6.12cm, and juvenile's 5.6cm, there are only 0.52cm difference between two products and just 0.4cm, size grading. These results are explained that even though when grow up to be a woman the distance between two bust points become to be long and breast toward out side but brassiere size don't vary with body characteristic.