• Title/Summary/Keyword: Competing risk model

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Estimation methods and interpretation of competing risk regression models (경쟁 위험 회귀 모형의 이해와 추정 방법)

  • Kim, Mijeong
    • The Korean Journal of Applied Statistics
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    • v.29 no.7
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    • pp.1231-1246
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    • 2016
  • Cause-specific hazard model (Prentice et al., 1978) and subdistribution hazard model (Fine and Gray, 1999) are mostly used for the right censored survival data with competing risks. Some other models for survival data with competing risks have been subsequently introduced; however, those models have not been popularly used because the models cannot provide reliable statistical estimation methods or those are overly difficult to compute. We introduce simple and reliable competing risk regression models which have been recently proposed as well as compare their methodologies. We show how to use SAS and R for the data with competing risks. In addition, we analyze survival data with two competing risks using five different models.

Competing Risk Model for Mobile Phone Service (이동통신시장 서비스를 위한 경쟁위험모형)

  • Lee, Jae Kang;Sohn, So Young
    • Journal of Korean Institute of Industrial Engineers
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    • v.32 no.2
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    • pp.120-125
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    • 2006
  • Since Korean government has implemented the "Number Portability System" in the domestic mobile communications market, mobile communication companies have been striving to hold onto existing customers and at the same time to attract new customers. This paper presents a competing risk model that considers the characteristics of a customer in order to predict the customer's life under the "Number Portability System." Three competing risks considered are pricing policy, quality of communication, and usefulness of service. It was observed that the customers who pay more are less sensitive on pricing policy younger people are less sensitive than older people to the quality of communication and women are more sensitive than men to the degree of usefulness of service. We expect that the result of this study can be used as a guideline for effective management of mobile phone customers under the Number Portability System.

Regression analysis of interval censored competing risk data using a pseudo-value approach

  • Kim, Sooyeon;Kim, Yang-Jin
    • Communications for Statistical Applications and Methods
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    • v.23 no.6
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    • pp.555-562
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    • 2016
  • Interval censored data often occur in an observational study where the subject is followed periodically. Instead of observing an exact failure time, two inspection times that include it are available. There are several methods to analyze interval censored failure time data (Sun, 2006). However, in the presence of competing risks, few methods have been suggested to estimate covariate effect on interval censored competing risk data. A sub-distribution hazard model is a commonly used regression model because it has one-to-one correspondence with a cumulative incidence function. Alternatively, Klein and Andersen (2005) proposed a pseudo-value approach that directly uses the cumulative incidence function. In this paper, we consider an extension of the pseudo-value approach into the interval censored data to estimate regression coefficients. The pseudo-values generated from the estimated cumulative incidence function then become response variables in a generalized estimating equation. Simulation studies show that the suggested method performs well in several situations and an HIV-AIDS cohort study is analyzed as a real data example.

Statistical analysis of economic activity state of workers with industrial injuries using a competing risk model (경쟁위험분석을 이용한 산재 근로자의 원직장복귀에 대한 연구)

  • Doh, Gippeum;Kim, Sooyeon;Kim, Yang-Jin
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.6
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    • pp.1271-1281
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    • 2015
  • Competing risk analysis is widely applied to analyze a failure time with more than two causes. This paper discusses the application of a competing risk model to a economic activity state of workers with occupational injuries. In particular, main interest is to estimate the distribution of restarting time two kinds of economic activities, (i) returning to original working place and (ii) finding a new job. In this paper, we applied a cumulative incidence function to evaluate their patterns under several individual factors and working place's factor. Furthermore, a subdistributional regression model is applied to estimate the effect of these factors on the returning time. According to result, worker with higher education, younger age and longer working period had a higher chance to return an original working place while one with more severe injuries and skilled laborer had longer returning time to an original working place.

Joint model of longitudinal data with informative observation time and competing risk (결시적 자료에서 관측 중단을 모형화하기 위해 사용되는 경쟁 위험의 적용과 결합 모형)

  • Kim, Yang-Jin
    • The Korean Journal of Applied Statistics
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    • v.29 no.1
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    • pp.113-122
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    • 2016
  • Longitudinal data often occur in prospective follow-up studies. Joint model for longitudinal data and failure time has been applied on several works. In this paper, we extend it to the case where longitudinal data involve informative observation time process as well as competing risks survival times. We use a likelihood approach and derive an EM algorithm to obtain maximum likelihood estimate of parameters. A suggested joint model allows us to make inferences for three components: longitudinal outcome, observation time process and competing risk failure time. In addition, we can test the association among these components. In this paper, liver cirrhosis patients' data is analyzed. The relationship between prothrombin times measured at irregular visiting times and drop outs is investigated with a joint model.

A Multivariate Mixture of Linear Failure Rate Distribution in Reliability Models

  • EI-Gohary A wad
    • International Journal of Reliability and Applications
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    • v.6 no.2
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    • pp.101-115
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    • 2005
  • This article provides a new class of multivariate linear failure rate distributions where every component is a mixture of linear failure rate distribution. The new class includes several multivariate and bivariate models including Marslall and Olkin type. The approach in this paper is based on the introducing a linear failure rate distributed latent random variable. The distribution of minimum in a competing risk model is discussed.

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A Mixture of Multivariate Distributions with Pareto in Reliability Models

  • El-Gohary Awad
    • International Journal of Reliability and Applications
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    • v.7 no.1
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    • pp.55-69
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    • 2006
  • This paper presents a new class of multivariate distributions with Pareto where dependence among the components is characterized by a latent random variable. The new class includes several multivariate and bivariate models of Marshall and Olkin type. It is found the bivariate distribution with Pareto is positively quadrant dependent and its mixture. Some important structural properties of the bivariate distributions with Pareto are discussed. The distribution of minimum in a competing risk Pareto model is derived.

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Survival of Colorectal Cancer Patients in the Presence of Competing-Risk

  • Baghestani, Ahmad Reza;Daneshvar, Tahoura;Pourhoseingholi, Mohamad Amin;Asadzade, Hamid
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6253-6255
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    • 2014
  • Background: Colorectal cancer (CRC) is considered to be a main cause of malignancy-related death in the world, being commonly diagnosed in both men and women. It is the third leading cause of cancer dependent death in the world and there are one million new cases diagnosed per year. In Iran the incidence of colorectal cancer has increased during the last 25 years and it is the fifth cause of cancer in men and the third in women. Materials and Methods: In this article we analyzed the survival of 475 colorectal patients of Taleghani hospital in Tehran with the semi-parametric competing-risks model. Results: There were 55% male cases and at the time of the diagnosis most of the patients were between 48 and 67years old. The probability of a patient death from colorectal cancer with survival of more than 25 years was about 0.4. Body mass index, height, tumour site and gender had no influence. Conclusions: According to these data and by using semi-parametric competing-risks method, we found out that only age at diagnosis has a significant effect on these patient survival time.

A Study on Determinants of the Elderly's Self-employment Exits - Focusing on why they exit from their owned business (중고령층 자영업 이탈 요인 분석: 자영업 이탈 이유를 중심으로)

  • Moon, Sanggyun;Park, Sae Jung
    • Journal of Labour Economics
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    • v.43 no.3
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    • pp.1-31
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    • 2020
  • This study analyzed the determinants of self-employment exits among the middle-aged and senior adults. For the analysis, we used KLoSA(Korean Longitudinal Study of Ageing) data from the first(2006) to the sixth(2016) and vocational data, which is a retrospective data surveyed in 2007. Among the reasons for exiting the self-employment, we find that the group that went out of their businesses due to management difficulties were more likely to have economic difficulties after the exit. Therefore, we analyzed the determinants of self-employment exits considering the exit reason due to management difficulties. The analysis model used a competing risk regression model that defined the only exit due to management difficulties as failures. As a result, the significance of gender, age, and education variables, which were well known as determinants of exiting the self-employment, disappeared. On the other hand, we find that the prior experience in the same industry tended to lower the risk of exiting the self-employment. To summarize the results, we suggest that we need some ways to help the middle-aged and senior adults who start their own businesses without any experience in the same industry to prevent them from failures.

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Constructing a Competing Risks Model for the Combined Structure with Dependent Relations (종속적 관계를 갖는 혼합구조에 대한 경쟁적 위험모형의 구축)

  • Park, Seonghwan;Park, Jihyun;Bae, Kiho;Ahn, Suneung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.3
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    • pp.92-98
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    • 2017
  • The rapid growth of engineering technology and the emergence of systemized and large-scale engineering systems have resulted in complexity and uncertainty throughout the lifecycle activities of engineering systems. This complex and large-scale engineering system consists of numerous components, but system failure can be caused by failure of any one of a number of components. There is a real difficulty in managing such a complex and large-scale system as a part. In order to efficiently manage the system and have high reliability, it is necessary to structure a system with a complex structure as a sub-system. Also, in the case of a system in which cause of failures exist at the same time, it is required to identify the correlation of the components lifetime and utilize it for the design policy or maintenance activities of the system. Competitive risk theory has been used as a theory based on this concept. In this study, we apply the competitive risk theory to the models with combined structure of series and parallel which is the basic structure of most complex engineering systems. We construct a competing risks model and propose a mathematical model of net lifetime and crude lifetime for each cause of failure, assuming that the components consisting a parallel system are mutually dependent. In addition, based on the constructed model, the correlation of cause of failure is mathematically analyzed and the hazard function is derived by dividing into net lifetime and crude lifetime.