• Title/Summary/Keyword: Compositional correlations

Search Result 13, Processing Time 0.019 seconds

Compositional Correlations in Canine Genome Reflects Similarity with Human Genes

  • Joy, Faustin;Basak, Surajit;Gupta, Sanjib Kumar;Das, Pranab Jyoti;Ghosh, Shankar Kumar;Ghosh, Tapash Chandra
    • BMB Reports
    • /
    • v.39 no.3
    • /
    • pp.240-246
    • /
    • 2006
  • The base compositional correlations that hold among various coding and noncoding regions of the canine genome have been analysed. The distribution pattern of genes, on the basis of $GC_3$ composition, shows a wide range similar to that observed in human. However the occurrence of maximum number of genes was observed in the range of 65-75% of $GC_3$ composition. The correlation between the coding DNA sequences of canine with the different noncoding regions (introns and flanking regions) is found to be significant and in many cases the degree of correlation show similarity to human genome. We found that these correlations are not limited to the GC content alone, but is holding at the level of the frequency of individual bases as well. The present study suggests that canines ideally belong to the predicted 'general mammalian pattern' of genome composition along with human beings.

A guideline for the statistical analysis of compositional data in immunology

  • Yoo, Jinkyung;Sun, Zequn;Greenacre, Michael;Ma, Qin;Chung, Dongjun;Kim, Young Min
    • Communications for Statistical Applications and Methods
    • /
    • v.29 no.4
    • /
    • pp.453-469
    • /
    • 2022
  • The study of immune cellular composition has been of great scientific interest in immunology because of the generation of multiple large-scale data. From the statistical point of view, such immune cellular data should be treated as compositional. In compositional data, each element is positive, and all the elements sum to a constant, which can be set to one in general. Standard statistical methods are not directly applicable for the analysis of compositional data because they do not appropriately handle correlations between the compositional elements. In this paper, we review statistical methods for compositional data analysis and illustrate them in the context of immunology. Specifically, we focus on regression analyses using log-ratio transformations and the alternative approach using Dirichlet regression analysis, discuss their theoretical foundations, and illustrate their applications with immune cellular fraction data generated from colorectal cancer patients.

Esthnation of the Heritabilities and Genetic Correlations on Egg Compositional Trsaits in Korean Native Chicken (한국재래계의 난구성분에 대한 유전력 및 유전상관의 추정)

  • 한성욱;상병찬;이준현;정욱수;상병돈
    • Korean Journal of Poultry Science
    • /
    • v.25 no.1
    • /
    • pp.11-19
    • /
    • 1998
  • This study was conducted to estimate the heritabilities and genetic correlations on egg weight and egg compositional traits for breeding plan and selection in Korean native chicken. Data analyzed were the records of 46,908 eggs from 430 layers produced from 180 dam and 26 sire families, from April, 1994 to September, 1995. On egg weight and egg compositional traits at 1st egg, 300 and 500 days of age, the egg weights were 41.489, 49.544 and 52.770g ; the albumin weights were 25.953, 29.979 and 31.288g; the yolk weights were 11.091, 14.541 and 16.368g; shell weights were 4.472, 5.037 and 5.099g, respectively. The estimates of heritability of egg weights and egg compositional traits based on the variance of sires, dams and combined components at 300 days of age were 0.214, 0.226 and 0.720 for egg weight ; 0.307, 0.152 and 0.730 for albumin weight ; 0.124, 0.953 and 0.699 for yolk weight ; 0.047, 0.026 and 0.536 for shell weight. The genetic correlation coefficient between egg weight and albumen weight was 0.083~0.951 ; 0.310~0.507 between egg weight and yolk weight ; 0.242~0.523 between egg weight and shell weight ; 0. 237~0. 413 between albumen weight and yolk weight ; 0.232~0.449 between albumen weight and shell weight ; -0.264~0.239 between yolk weight and shell weight, respectively.

  • PDF

The alignment between contextual and model generalization: An application with PISA 2015

  • Wan Ren;Wendy Chan
    • Communications for Statistical Applications and Methods
    • /
    • v.31 no.5
    • /
    • pp.467-485
    • /
    • 2024
  • Policymakers and educational researchers have grown increasingly interested in the extent to which study results generalize across different groups of students. Current generalization research in education has largely focused on the compositional similarity among students based on a set of observable characteristics. However, generalization is defined differently across various disciplines. While the concept of compositional similarity is prominent in causal research, generalization among the statistical learning community refers to the extent to which a model produces accurate predictions across samples and populations. The purpose of this study is to assess the extent to which concepts related to contextual generalization (based on compositional similarity) are associated with the ideas related to model generalization (based on accuracy of prediction). We use observational data from the Programme for International Student Assessment (PISA) 2015 wave as a case study to examine the conditions under which contextual and model generalization are aligned. We assess the correlations between statistical measures that quantify compositional similarity and prediction accuracy and discuss the implications for generalization research.

Source Evaluation of Rhyolitic Dike Swarm from Compositional Correlations of Igneous Intrusions in the Northern Cheongsong, Korea (청송 북부 화성관입체들의 조성대비에 의한 청송 암맥군의 공급원 고찰)

  • Hwang, Sang Koo;Kwon, Tae Ho;Kim, Hyo Jin;Ahn, Ung San;Jeong, Gi Young
    • The Journal of the Petrological Society of Korea
    • /
    • v.27 no.2
    • /
    • pp.73-84
    • /
    • 2018
  • In the northern Cheongsong, there are occurred igneous intrusions: Cheongsong dike swarm, Jungtaesan laccolith, Galpyeongji stock. The swarm is composed of rhyolitic dikes that have developed many various spherulites. The dikes represent an geometrically radical pattern centering the Galpyeongji stock, but also geochemistry of the intrusions indicate the swarm source. Here we report the compositional data for 28 samples from the three intrusions. All of the intrusions belong to rhyolitic composition, but according to compositional correlation, there are considerable overlaps between intrusion compositions. In particular, the Cheongsong dike swarm is divided into several dike groups by rock color and shows compositional diversity, but the composition of the dikes generally overlap with compositions of other intrusions. The Jungtaesan laccolith is enriched in alkali, $K_2O$ and $Al_2O_3$ and depleted in $Fe_2O_3{^t}$, $TiO_2$ and REE compared to the Cheongsong dike swarm. In contrast, the Galpyeongji stock is narrow in composition range, and commonly has sharp compositional overlaps with the Cheongsong dike swarm. According to the compositional correlations, the stock is considered to be a source of the swarm and it is connected to an episode of volcanism.

Tissue Specific Expression Levels of Apoptosis Involved Genes Have Correlations with Codon and Amino Acid Usage

  • Hajjari, Mohammadreza;Sadeghi, Iman;Salavaty, Abbas;Nasiri, Habib;Birgani, Maryam Tahmasebi
    • Genomics & Informatics
    • /
    • v.14 no.4
    • /
    • pp.234-240
    • /
    • 2016
  • Different mechanisms, including transcriptional and post transcriptional processes, regulate tissue specific expression of genes. In this study, we report differences in gene/protein compositional features between apoptosis involved genes selectively expressed in human tissues. We found some correlations between codon/amino acid usage and tissue specific expression level of genes. The findings can be significant for understanding the translational selection on these features. The selection may play an important role in the differentiation of human tissues and can be considered for future studies in diagnosis of some diseases such as cancer.

Anthropometric and Body Compositional Measurements and Pregnancy Outcomes (임신부의 체위와 체조성 및 임신의 결과)

  • 이종임;임현숙;조영숙
    • Journal of Nutrition and Health
    • /
    • v.31 no.6
    • /
    • pp.1057-1065
    • /
    • 1998
  • Anthropometric and body compositional changes and the outcomes of the pregnancies of 90 healthy Korean women were investigated in a longitudinal study. Their weight increased from 51.3$\pm$5.9kg to 65.1$\pm$7.8kg during their pregnancies. The total weight gain was 13.8$\pm$4.5kg, and therefore, weekly weight gain was 340$\pm$110g during the entire period of the pregnancy. The weight gain was composed of approximately 50-60% fat mass and 40-50% fat-free mass. Skinfold thicknesses, both of triceps and subscapular, increased during the pregnancies. The fat mass calculated from skinfold thickness and that measured with bioelectrical impedance analysis went on increasing during the pregnancies. Although there was a considerable difference with respect to the fat mass observed using the three methods, fat mass gain was 5.0-6.1kg and fat-free mass gain was 4.0-5.3kg from the first trimester to the third trimester of pregnancies. There were significant correlations between maternal anthropometric parameters and indices of pregnancy outcomes. Especially, the infant's birth weight was associated with maternal pre-pregnancy weight and weight gains during the pregnancies. The infant's birth length was related to the maternal weight observed at term(p<0.05) and weight gain during the entire pregnancies (p<0.05) . Neither increase of fat mass nor fat-free mass affected the outcomes of pregnancy. These results show that maternal weight gain during pregnancy is led by increments of approximately above 50% fat mass. The fat mass increase seems to be larger in central areas than in subcutaneous areas. Maternal weight gain during pregnancy, especially during late pregnancy, is a factor affecting the birth weight and length of infant. On the basis of the body compositional changes, it can be predicted that the additional energy requirement for pregnancy in Korean women is more than 200-230 MJ (64,500-76,250kca1). (Korean J Nutrition 31(6) : 1057-1065, 1998)

  • PDF

Skarn-Ore Associations and Phase Equilibria in the Yeonhwa-Keodo Mines, Korea (태백산광화대(太白山鑛化帶) 연화(蓮花)-거도광산(巨道鑛山)에 있어서의 스카른과 광석광물(鑛石鑛物)의 수반관계(隨伴關係) 및 상평형(相平衡))

  • Yun, Suckew
    • Economic and Environmental Geology
    • /
    • v.16 no.1
    • /
    • pp.1-10
    • /
    • 1983
  • The Yeonhwa (I, II) and Keodo mines, neighboring in the middle part of the Taebaegsan mineral belt, contain three distinct classes of skarn deposits: the zinc-lead skarn at Yeonhwa (I, II), the iron skarn at Keodo south (Jangsan orebodies), and the copper skarn at Keodo north (78 orebodies). The present study characterizes the three classes of skarn deposits mainly in terms of skarn/ore associations examined from chemical compositional point of view, and applies existing quantitative phase diagrams to some pertinent mineral assemblages in these mines. At Yeonhwa I the Wolam I orebody shows a vertical variation in skarn minerals ranging from clinopyroxene/garnet zone on the lower levels through clinopyroxene (without garnet) zone on the intermediate levels, and finally to rhodochrosite veins on the upper levels and surface. Ore minerals, sphalerite and galena, associate most closely with the intermediate clinopyroxene zone. At Keodo, the Jangsan iron skarn hosted in quartz monzodiolite as a typical endoskarn, shows a skarn zoning, from center of orebody to outer side, magnetite zone, magnetite/garnet zone, garnet clinopyroxene zone, and clinopyroxene/epidote/plagioclase zone. The 78 copper skarn in the Hwajeol limestone indicates a zoning, from quartz porphyry side toward limestone side, orthoclase/epidote zone, epidote/clinopyroxene zone, and clinopyroxene/garnet zone; chalcopyrite and other copper sulfides tend to be in clinopyroxene/garnet zone. Mioroprobe analyses of clinopyroxenes and garnets from the various skarn zones mentioned above revealed that the Yeonhwa zinc/lead skarns are characterized by johansenitic clinopyroxene (Hd 25-78, Jo 15-23) and manganoan andraditic garnet (Ad 13-97, Sp 1-24), whereas the Jangsan iron skarn at Keodo by Mn-poor diopsidic clinopyroxene (Di 78-93, Jo 0.2-1.0) and Mn-poor grossularitic grandite (Gr 65-77, Sp 0.5-1.0). The 78 copper skarn at Keodo is characterized by Mn-poor diopsidic-salite (Di 66-91, Jo 0.2-1.1) and Mn-poor andraditic grandite(Ad 40-74, Sp 0.5-1.1). The compositional charateristics of iron, copper, and zinc-lead skarns in the Yeonhwa-Keodo mines are in good correlations with those of the foreign counterparts. Compiling a $T-XCO_2$ phase diagram for the Jangsan endoskarns, a potential upper limit of temperature of the main stage of skarn formation is estimated to be about $530^{\circ}C$, and a lower limit to be $400^{\circ}C$ or below assuming $XCO_2=0.05$ at P total=1kb. Applying a published log $fS_2$-log $fo_2$ diagram to the Keodo 78 and Yeonhwa exoskarns, it is revealed that copper sulfides and zinc-lead sulfides do not co-exist stably below log $fS_2=-4$ and log $fO_2=-23$ at $T=400^{\circ}C$ and ${\times}CO=1$ atm.

  • PDF

On the Homotoneity of Species Composition in the Phytosociologically Synthesized Community Tables (식물사회학적 식생자료의 종조성 균질성에 대하여)

  • Kim, Jong-Won;Eom, Byeong-Cheol
    • Korean Journal of Environment and Ecology
    • /
    • v.31 no.5
    • /
    • pp.433-443
    • /
    • 2017
  • Securing the species compositional integrity (typicalness and representativeness) is the essential prerequisite for an integrated management of vegetation resources using the phytosociological $relev\acute{e}s$ and plant communities of the Z.-M. school. This study is intended to develop a tool for qualitative and quantitative evaluation of species compositional homotoneity of a set of $relev\acute{e}s$ per syntaxon. The new homotoneities, actual homotoneity ($H_{act}$), and optimal homotoneity ($H_{opt}$) taking into account the heterogeneous factors of $relev\acute{e}s$ are proposed. The correlations between the floristic variables such as the vegetation type, the new homotoneities, and the previously studied homogeneous measures (e.g. Pfeiffer's homogeneity, basic homotoneity-coefficient, corrected homotoneity-coefficient, and mean floristic similarity) are analyzed by using Spearman's rank correlation coefficient. $H_{act}$ and $H_{opt}$ are effective in determining the difference of inter-synthesized units and of inter-$relev\acute{e}s$, respectively. $H_{act}$ is the homotoneity that is the most independent of the number of $relev\acute{e}s$. On actual vegetation with long-term human impact in the Korean Peninsula, $H_{opt}$ has become an aid to the more precise understanding of $H_{act}$ as substantive homogeneousness of species composition of syntaxa. It is expected that $H_{act}$ and $H_{opt}$ can be used for the selection of a sort of homogeneous vegetation data to build a phytosociological $relev\acute{e}$-database with consistency and objectiveness for national vegetation resources.

Geochemical Study on Pegmatites in Central Region of Taebaek Mineralized Area (태백산(太白山) 광화대(鑛化帶) 중부지역(中部地域) 페그마타이트에 대한 지화학적(地化學的) 연구(硏究))

  • Choi, Sung-Hoon;Chi, Jeong-Mahn
    • Economic and Environmental Geology
    • /
    • v.23 no.1
    • /
    • pp.35-57
    • /
    • 1990
  • This study has been carried out on the Pegmatites, Naedeogri Granites, Nonggeori Granites and Metasedimentary rocks in the middle area of Taebaeksan region to investigate the geochemical properties and possibility of productivity. Pegmatites are characterized by metamorphosed anatectic pegmatite and differentiated magmatic pegmatite, and are mixed type of rare-element pegmatite and mica-bearing pegmatite by the classification of Ginsburg(1979). The petrological type of the igneous rocks is thought to be calcalkali, subalkaline and peralumious. According to chemical variations against D. I., differentiation trends from Naedeogri and Nonggeori Granites through non-mineralized pegmatites to mineralized pegmatites are supposed. From the relationship between oxided and $SiO_2$, pegmatites and Nonggeori Granite have shown similar tendencies and bulk composition of pegmatites and similar to metasedimentary rocks near the intrusives. By judging the correlations of trace elements, it is elucidated that pegmatites adjacent to Naedeogri and Nonggeori Granites have been originated in magma differentiation from these granites and the others have been differentiated by remelting or partial melting from metasedimentary rocks. $Sp_5$, $Sp_8$, and $Sp_9$ pegmatites are considered as productive rocks, and $Sp_4$, $Sp_6$, $Sp_7$, $Sp_{10}$, $Sp_{11}$, and $Sp_{12}$ pegmatites and granites are supposed to have a weak productivity, in terms of element ratios related with Sn mineralizations. Tourmalines in productive pegmatites are formed under the circumstance of Li-poor granitoids and associated with pegmatites, and the others are seemed to be originated in metapelites and metapsammites which are not coexisting with an Al-saturating phase. Three types of chemical zoning are noticed in tourmalines: (1) apparently homogeneous compositional patterns, (2) a continuous core-to-rim zoning and, (3) a discontinuous core-to-rim zoning. From results of EPMA of tourmalines, Al, Mg and Ca increase closer to rim, while Fe decreases.

  • PDF