• Korean Journal of Adult Nursing
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• v.23 no.1
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• pp.10-19
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• 2011

Purpose: The purpose of this study was to evaluate the impact of a protocol of cryotherapy and Tai Chi on women with Fibrolmyalgia Syndrome. Methods: The study design was a pretest and posttest quasi-experimental, nonrandom assignment. The subjects were 48 outpatients with a diagnosis of fibromyalgia based on the American College of Rheumatology Standards. The setting was a University Medical Center in S city. The protocol was self administered ten times a week, for a two week period resulting in twenty treatments. Results: A protocol of cryotherapy and Tai Chi self-help program showed significant improvement in the fibromyalgia impact as measured by reports of physical impairment, feeing good, number of missed work days, ability to perform work, reports of pain, fatigue, rest, stiffness, anxiety and depression as reported by the comparison group (p<.001). No significant differences between the two regarding in reports of the tender points (p=.062). Conclusion: The results suggested that a protocol of cryotherapy and Tai Chi self-help program may be a promising multidisciplinary strategy for fibromyalgia patients.

• Journal of International Academy of Physical Therapy Research
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• v.5 no.1
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• pp.647-651
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• 2014

The purpose of this study is to provide the case of influence of myofacial release(MFR) and cryotherapy in acute whiplash injury. The subjects were consisted of 3 adults(2 males, 1 female) who had been diagnosed with whiplash injury. The performance period was 1 weeks, 6 times and 1 time is 40min(MFR: 20min, cryotherapy: 20min). We measured neck pain(Visual analogue scale, VAS) and cervical alignment(cervical curvature & line of gravity). All measurements of each subject were measured at pre-treatment and post-treatment. The results are listed below. The neck pain(VAS) index decreased from 7.54cm to 4.11cm. The cervical curvature increased from $23.62^{\circ}$ to $29.76^{\circ}$. The line of gravity decreased from 8.03mm to 3.66mm. Based on the results, it can be suggested that both MFR and cryotherapy can be used to neck pain and alignment in acute whiplash injury.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.388-391
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• 1997

A cryotherapy system using the low temperature air was developed. The developed cryotherapy system had superior low temperature characteristics and many safety devices. For a clinical evaluation, skin and intra-articular temperatures of the knee joint were measured during and after the cryotherapy. After 5-minute therapy, skin and intra-articular temperature decreased by $23.3{\pm}4.7(^{\circ}C)$ and $4.1{\pm}1.0(^{\circ}C)$ respectively. A 5-minute cryotherapy therapy is good enough to maintain low intra-articular temperatures or 2-3 hours.

• Restorative Dentistry and Endodontics
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• v.48 no.3
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• pp.29.1-29.8
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• 2023

Objectives: This study tested the hypothesis that cryotherapy duration influences lipopolysaccharide (LPS)-induced inflammation in a rat model. Materials and Methods: Six Wistar rats (Rattus norvegicus albinus) were used. Five sites were selected per animal and divided into 5 groups: a negative control group (NC), 2 positive control groups (PC1 and PC2), and 2 experimental groups (E1 and E2). Cryotherapy was applied for 1 minute (E1) or 5 minutes (E2). An acute inflammatory response was induced in the PC and E groups via subcutaneous administration of 0.5 mL/kg. In the PC2 group, a catheter was inserted without additional treatment. For the E1 and E2 groups, 2.5℃ saline solution was administered through the implanted catheters for 1 and 5 minutes, respectively. The rats were sacrificed, and samples were obtained and processed for histological analysis, specifically examining the presence of polymorphonuclear neutrophils and hemorrhage. The χ² test was used to compare the presence of acute inflammation across groups. Dependent variables were compared using the linear-by-linear association test. Results: Inflammation and hemorrhage varied significantly among the groups (p = 0.001). A significantly higher degree of acute inflammation was detected (p = 0.0002) in the PC and E1 samples than in the E2 group, in which cryotherapy was administered for 5 minutes. The PC and E1 groups also exhibited significantly greater numbers of neutrophils (p = 0.007), which were essentially absent in both the NC and E2 groups. Conclusions: Cryotherapy administration for 5 minutes reduced the acute inflammation associated with LPS and catheter implantation.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.5
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• pp.272-278
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• 2023

Attention, an important element of human cognitive function, is an important cognitive function that focuses only on necessary stimuli from various stimuli through sensory systems. Although various studies have shown that environmental conditions may affect the level of attention, the effect on attention by applying cooling directly to the skin has not been studied much. Differences in attention depending on when and whether cryotherapy was applied during learning and relaxation activities were examined among 36 subjects. The FAIR attention test, a visual attention evaluation tool, was used, and statistical analysis was conducted on the results of the sub-index of FAIR: Performance index, Quality index, and Continuity index. Among participants who performed rest activities, the application of cryotherapy appeared to have no effect on any subindex. Among the participants who performed learning activities, the group that applied pre-cryotherapy (P=469.0, C=435.4)) and the group that applied post-cryotherapy (P=457.4, C=425.4) showed higher Performance index and Continuity index than the group that did not apply cryotherapy (P=335.8, C=301.7). From these results, it can be concluded that cryotherapy maintains the level of alertness and awakens attention, albeit to a limited extent.

• Tuberculosis and Respiratory Diseases
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• v.77 no.4
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• pp.193-196
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• 2014

Acute airway obstruction after hemoptysis occurs due to the presence of blood clots. These conditions may result in lifethreatening ventilation impairment. We report a case of obstruction of the large airway by endobronchial blood clots which were removed using bronchoscopic cryotherapy at the bedside of intensive care unit. A 66-year-old female with endometrial cancer who had undergone chemotherapy, was admitted to the intensive care unit due to neutropenic fever. During mechanical ventilation, the minute ventilation dropped to inadequately low levels and chest radiography showed complete opacification of the left hemithorax. Flexible bronchoscopy revealed large blood clots obstructing the proximal left main bronchus. After unsuccessful attempts to remove the clots with bronchial lavage and forceps extraction, blood clots were removed using bronchoscopic cryotherapy. This report shows that cryotherapy via flexible bronchoscopy at the bedside in the intensive of intensive care unit is a simple and effective alternative for the removal of endobronchial blood clots.

• Physical Therapy Korea
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• v.7 no.1
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• pp.22-31
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• 2000

Despite research to treat delayed onset muscle soreness (DOMS), no effective treatment has been reported. The purpose of this study is to investigate the effect of a hold-relax technique and cryotherapy on DOMS. Thirty-three subjects were randomly assigned to one of three treatment groups: control, hold-relax technique, or hold-relax technique and cryotherapy. DOMS was induced in the non-dominant biceps muscle through repeated eccentric contractions. Resting elbow joint position, flexion and extension (universal goniometer), pain (Visual Analogue Scale; VAS), and WBC count (blood analysis) were measured one hour before DOMS was induced and 24, 48, and 72 hours after DOMS was induced. The data were analyzed by repeated measure of two-way ANOVA. The results of this study were summarized as follows: 1) While analysis showed no significant differences between groups in relation to a resting elbow joint position, there were significant differences over time, especially at 24, 48 hours after DOMS was induced compared with resting elbow joint position before DOMS was induced. 2) While analysis showed no significant differences between groups in relation to range of flexion, there were significant differences between range of flexion before DOMS was induced and range of flexion 72 hours after DOMS was induced. 3) There were no significant differences between groups or over time in relation to range of extension. 4) While analysis showed no significant differences between groups in relation to VAS, there were significant differences over time in different hours. 5) There were no significant differences between groups or over time in relation to WBC count. 6) There were no interactions between groups or over time in all variables. This results suggested that hold-relax technique and cryotherapy were not effective to reduce DOMS.

• The Journal of Korean Physical Therapy
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• v.13 no.3
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• pp.653-664
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• 2001

Delayed onset muscle soreness (DOMS) was the sensation of discomfort and stiffness in the muscle, often after taking part in unaccustomed physical activity. No universally accepted treatment exist. The aim of this study was to examine the influence of cryotherapy and intermittent compression on the delayed onset muscle soreness. Flexion elbow joint position and extension(Universal Goniometer). pain(Muscle Soreness Rating Scale) and mechanical pain threshold(Algometer) were measured before 30minutes DOMS was induced.The data were analyzed by measure of Mann-Whitney test and Kruskal-Wallis test. The result were as follow; 1. There were no significantly differences between groups or over time in relation to range of motion. 2. Muscle Soreness Rating was significantly high in cryotherapy and intermittent compression at 48, 72 hours after DOMS was induced(p<.05). 3. Mechanical pain threshold begin to increased at 24 hours and significantly in cryotherapy and intermittent compression groups at 48, 72 hours after DOMS was induced(p>.05). 4. A negative Correlation between muscle soreness rating scale and mechanical Pain threshold graphs at 24, 48, and 72 hours after exercise indicated in cryotherapy and intermittent compression groups.

• Journal of Korean Academy of Nursing
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• v.49 no.2
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• pp.149-160
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• 2019

Purpose: The purpose of this study was to examine the effects of oral cryotherapy on oral mucositis, reactive oxygen series, inflammatory cytokines, and oral comfort in patients undergoing chemotherapy for gynecologic cancers. Methods: Participants were randomly assigned to the experimental group (n=25, receiving oral cryotherapy during chemotherapy) and the control group (n=25, receiving the usual care consisting of 0.9% normal saline gargles three times before meals). Oral mucositis was assessed using the oral assessment guide, while oral comfort was assessed using the oral perception guide. Reactive oxygen series was measured as total oxidant stress, and the level of two inflammatory markers, interleukin-6 (IL-6) and tumor necrosis factor-alpha ($TNF-{\alpha}$), were examined. The data were analyzed using t-test, chi-square test, Fisher's exact test, Mann-Whitney U-test, and repeated measures analysis of variance. Results: There was a significant difference in the oral mucositis score, reactive oxygen series score, $TNF-{\alpha}$ level, and oral comfort score between the two groups, and there were significant changes over time and in the group-by-time interactions. There was a significant difference in the IL-6 score between the two groups, but there were no significant changes over time or in the group-by-time interactions. Conclusion: The study results revealed that oral cryotherapy was more effective than the usual care regime of normal saline gargles for reducing oral mucositis, reactive oxygen series, and inflammatory cytokines and for improving oral comfort in gynecologic cancer patients undergoing chemotherapy.

• PNF and Movement
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• v.21 no.1
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• pp.37-45
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• 2023

Purpose: Whiplash-associated disorder is often caused by external impact, such as a car accident, and it involves acceleration and deceleration of the flexion and extension of the neck. The purpose of this study is to determine whether the combination of cyrotherapy and a joint mobilization intervention in patients with acute whiplash-associated disorder is effective for pain, cervical range of motion (ROM), and muscle tone in the neck muscles. Methods: In this study, 20 patients with acute whiplash-associated disorder were randomly assigned to two groups. Group A was treated with cyrotherapy for 5 minutes, while group B was treated with cyrotherapy and a joint mobilization intervention. In both groups, visual analogue scale (VAS), neck disability index (NDI), cervical ROM, and muscle tone values were measured pre- and post-intervention. Results: According to the VAS values, both groups showed significant differences pre- and post-intervention (p<0.05), and in both groups, NDI was significantly decreased pre- and post-intervention (p<0.05). Finally, in terms of muscle tone, both groups showed significant changes before and after the intervention (p<0.05). Conclusion: These results showed that cryotherapy and joint mobilization can be effective interventions in patients with whiplash-associated disorder. In addition, to improve the ROM of the cervical joint and reduce NDI, the combination of cryotherapy and joint mobilization is considered more effective than the single intervention of cryotherapy.