• Title/Summary/Keyword: DCC

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ROLE OF DCC(DELETED IN COLORECTAL CANCER) GENE IN ORAL SQUAMOUS CELL CARCINOMA (구강편평상피암종에서 DCC 유전자의 역할)

  • Ko, Seong-Kyu;Han, Se-Jin;Kim, Kyung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.5
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    • pp.518-524
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    • 2008
  • Chromosome 18q alteration plays a key role in colorectal tumorigenesis, and loss of heterozygosity at 18q is associated with a poor prognosis in colon cancer. DCC(Deleted in Colorectal Cancer) is a putative tumor- suppressor gene at 18q21 that encodes a transmembrane protein with structural similarity to neural cell adhesion molecule that is involved in both epithelial and neuronal cell differentiation. DCC is implicated in regulation of cell growth, survival and proliferation. Thus, tumor progression in squamous cell carcinoma, stomach cancer, colorectal cancer correlates with downregulation of DCC expression. The mechanism for DCC suppression is associated with hypermethylation of the DCC gene promoter region. Hence, the goal of this study is to identify the promoter methylation responsible for the down-regulation of DCC expression in oral squamous cell carcinoma. 12 of tissue specimens for the study are excised and gathered from 12 patients who are diagnosed as SCC in department of OMS, dental hospital, dankook university. To find expression of DCC in each tissue samples, immunohistochemical staining, RT-PCR gene analysis and methylation specific PCR are processed. The results are as follows. 1. In the DCC gene RT-PCR analysis, 5(41.6%) of 12 specimens of oral squamous cell carcinoma did not expressed DCC gene. 2. In the promoter methylation specific PCR analysis, 5(41.6%) of 12 specimens showed promoter methylation of DCC gene. 3. In the immunohistochemical staining of poor differentiated and invasive oral squamous cell carcinoma, loss of DCC expression was observed. These findings suggest that methylation of the DCC gene may play a role in loss of gene expression in invasive oral squamous cell carcinoma.

Control Effect of Sodium Dichloroisocyanurate for Pear Scab (Venturia nashicola) on Niitaka Pear during Flowering Period (신고배 개화기 NaDCC 처리에 의한 검은별무늬병의 방제)

  • Nam, Ki-Woong;Han, Mi-Kyong;Yoon, Deok-Hoon
    • Korean Journal of Organic Agriculture
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    • v.22 no.2
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    • pp.347-357
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    • 2014
  • This study was conducted to evaluate the control effect of sodium dichloroisocyanurate (NaDCC) for Venturia nashicola on Niitaka pear during flowering period. As a nontoxic disinfectant, sodium dichloroisocyanurate is widely used in the field of hygiene and disease prevention, medical treatment, aquiculture as well as plant protection. NaDCC was sprayed on the pear tree inoculated with conidia ($4.5{\times}10^5spores/mL$) of Venturia nashicola and as a result the incidence of pear scab was 23.8% in 750mg/L and 26.2% in 1,000mg/L compare to the 51.6% incidence in untreated tree. No damage in the pollen of pear flower was detected with NaDCC treatments in the full bloom period for six pear cultivar including Wonwhang. A NaDCC single treatment in the early bloom of Niitaka pear showed more than 98% of fertilization rate. Furthermore, there was no incidence of Venturia nashicola on Nitaka pear trees treated with NaDCC 4 times during their growth period.

Fast Image Compression and Pixel-wise Switching Technique for Hardware Efficient Implementation of Dynamic Capacitance Compensation (하드웨어 효율적인 동적 커패시턴스 보상 구현을 위한 고속 영상 압축 및 화소별 스위칭 기법)

  • Choi, Joon-Hwan;Song, Won-Suk;Choi, Hyuk
    • Journal of KIISE:Software and Applications
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    • v.36 no.8
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    • pp.616-622
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    • 2009
  • Thanks to Dynamic Capacitance Control (DCC) technique, response time of an LCD display has greatly improved. However, DCC requires hi-speed memory for the real-time writing/reading of an image of a previous frame, which results in increases in hardware overhead and cost. In this paper, we propose Modified Exponential Golomb (MEG) coding, a low-complex high-speed image compression method, which can remarkably reduce memory requirement for DCC. We also propose a pixel-wise DCC switching technique to prevent a compression error from affecting the quality of a final image on LCD. In our experiment, the degradation in visual quality was not noticeable when we cut the DCC memory size of 1080i HD data by 1/3.

Deep Reinforcement Learning-Based C-V2X Distributed Congestion Control for Real-Time Vehicle Density Response (실시간 차량 밀도에 대응하는 심층강화학습 기반 C-V2X 분산혼잡제어)

  • Byeong Cheol Jeon;Woo Yoel Yang;Han-Shin Jo
    • Journal of IKEEE
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    • v.27 no.4
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    • pp.379-385
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    • 2023
  • Distributed congestion control (DCC) is a technology that mitigates channel congestion and improves communication performance in high-density vehicular networks. Traditional DCC techniques operate to reduce channel congestion without considering quality of service (QoS) requirements. Such design of DCC algorithms can lead to excessive DCC actions, potentially degrading other aspects of QoS. To address this issue, we propose a deep reinforcement learning-based QoS-adaptive DCC algorithm. The simulation was conducted using a quasi-real environment simulator, generating dynamic vehicular densities for evaluation. The simulation results indicate that our proposed DCC algorithm achieves results closer to the targeted QoS compared to existing DCC algorithms.

Public ATM Networks and AESA Address (공중 ATM 망과 AESA 주소체계)

  • 김상현;송호영주성순
    • Proceedings of the IEEK Conference
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    • 1998.10a
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    • pp.301-304
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    • 1998
  • 이 논문에서는 ITU-T E.164 및 AESA ICD/DCC 주소체계 및 형태를 비교분석하고, 공중 ATM 망에서 ITU-T E.164 주소체계외에 AESA ICD, DCC 주소체계를 수용할 경우 E.164 및 AESA ICD/DCC 주소형태(format), AESA ICD/DCC 주소체계를 사용한 망 계획 및 ATM 망에서 이러한 주소체계를 수용하여야 하는 이유를 분석하였다. 그리고 공중망 및 사설망을 포함한 전체 ATM 망에서 AESA ICD/DCC 주소체계를 사용할 경우 AESA ICD/DCC 주소형태(format)에 포함되어야 하는 서브 계위(hierarchy)와 이들을 사용한 망 계획 방안을 제시하였다. 본 논문에서 제시한 내용은 AESA ICD 주소체계를 수용할 경우에도 유사하게 적용되어야 할 것으로 판단된다.

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Design of clock duty-cycle correction circuits for high-speed SoCs (고속 SoC를 위한 클락 듀티 보정회로의 설계)

  • Han, Sang Woo;Kim, Jong Sun
    • Journal of Korea Society of Industrial Information Systems
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    • v.18 no.5
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    • pp.51-58
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    • 2013
  • A clock duty-cycle corrector (DCC) which is an essential device of clocking circuits for high-speed system-on-chip (SoC) design is introduced in this paper. The architectures and operation of conventional analog feedback DCCs and digital feedback DCCs are compared and analyzed. A new mixed-mode feedback DCC that combines the advantages of analog DCCs and digital DCCs to achieve a wider duty-cycle correction range, higher operating frequency, and higher duty-cycle correction accuracy is presented. Especially, the architectures and design of a mixed-mode duty-cycle amplifier (DCA) which is a core unit circuit of a mixed-mode DCC is presented in detail. Two mixed-mode DCCs based on a single-stage DCA and a two-stage DCA were designed in a 0.18-${\mu}m$ CMOS process, and it is proven that the two-stage DCA-based DCC has a wider duty-cycler correction range and smaller duty-cycle correction error.

Effect of Gamma Irradiation and Its Convergent Treatments on Lily Leaf Blight Pathogen, Botrytis elliptica, and the Disease Development (감마선 및 화학 대체제 융복합 처리가 백합 잎마름병균 및 잎 절편 감염에 미치는 영향)

  • Kim, Ji-Hoon;Yun, Sung-Chul
    • Research in Plant Disease
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    • v.20 no.2
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    • pp.71-78
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    • 2014
  • Gamma irradiation and its convergence with nano-silver particles and sodium dichloroisocyanurate (NaDCC) were investigated to inhibit germination and mycelial growth of Botrytis elliptica, the pathogen of lily leaf blight. In addition, the same treatments were studied on the process of disease development with detached leaf of lily cv. Siberia. Spray inoculation, which is closer to natural infection than wound inoculation, can be a way to investigate infection ability of the treated pathogen. The irradiating dose required to reduce the population by 90%, $D_{10}$, was 526 Gy irradiating with 0-2000 Gy gamma ray on the conidial suspension as well as the growing mycelia. Even at 2000 Gy, the mycelium was not killed but just delayed its growth at 1-2 days behind. Convergent treatment with 40 mg/l of NaDCC just before 200 Gy gamma irradiation was the best way to decrease the conidial germination about 1/1000 times. The control values of gamma irradiation were 23% and 19.5% at wound inoculation and spray inoculation, respectively. On wound-inoculation, the control value of NaDCC only was 89%, and that of NaDCC convergent with 200 Gy gamma irradiation was 32%. On sprayinoculation, the highest control value was NaDCC at 50%, and that of NaDCC convergent with gamma irradiation was 24%.

DLL Design of SMD Structure with DCC using Reduced Delay Lines (지연단을 줄인 SMD 구조의 DCC를 가지는 DLL 설계)

  • Hong, Seok-Yong;Cho, Seong-Ik;Shin, Hong-Gyu
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.6
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    • pp.1133-1138
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    • 2007
  • DLLs(Delay Locked Loops) have widely been used in many systems in order to achieve the clock synchronization. A SMD (Synchronous Mirror Delay) structure is used both for skew reduction and for DCC (Duty Cycle Correction). In this paper, a SMD based DLL with DCC using Reduced Delay Lines is proposed in order to reduce the clock skew and correct the duty cycle. The merged structure allows the forward delay array to be shared between the DLL and the DCC, and yields a 25% saving in the number of the required delay cells. The designed chip was fabricated using a $0.25{\mu}m$ 1-poly, 4-metal CMOS process. Measurement results showed the 3% duty cycle error when the input signal ranges from 80% to 20% and the clock frequency ranges from 400MHz to 600MHz. The locking operation needs 3 clock and duty correction requires only 5 clock cycles as feature with SMD structure.

Study on the Synthesis of N,N'-Dicyclohexylcarbodiimide from N,N'-Dicyclohexylurea (디사이클로헥실우레아로부터 디사이클로헥실카르보디이미드의 합성에 관한 연구)

  • Kim, Jae Young;Chung, Dae-Won
    • Applied Chemistry for Engineering
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    • v.22 no.3
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    • pp.319-322
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    • 2011
  • N,N'-Dicyclohexylcarbodiimide (DCC) known as powerful dehydrating reagent in amide or ester synthesis is converted into N,N'-dicyclohexylurea (DCU) during the reaction. In the paper, DCU was recovered from the reaction for the synthesis of the hydrophilic derivative of ${\beta}$-sitosterol, and the purification of the recovered DCU and the dehydration of DCU into DCC were investigated. In the presence of tosyl chloride, (TsCl) and triethylamine (TEA), DCU was converted into DCC, and the optimum molar ratio of [DCU] : [TsCl] : [TEA] was found to be 1.0 : 1.5 : 3.0. Pure DCC was obtained with a 46% yield by the sublimation after the purification process, and characterized by GC/MS, FT-IR and $^{13}C-NMR$.

Analysis of Multivariate-GARCH via DCC Modelling (DCC 모델링을 이용한 다변량-GARCH 모형의 분석 및 응용)

  • Choi, S.M.;Hong, S.Y.;Choi, M.S.;Park, J.A.;Baek, J.S.;Hwang, S.Y.
    • The Korean Journal of Applied Statistics
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    • v.22 no.5
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    • pp.995-1005
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    • 2009
  • Conditional correlation between financial time series plays an important role in risk management, asset allocation and portfolio selection and therefore diverse efforts for modeling conditional correlations in multivariate-GARCH processes have been made in last two decades. In particular, CCC (cf. Bollerslev, 1990) and DCC(dynamic conditional correlation, cf. Engle, 2002) models have been commonly used since they are relatively parsimonious in the number of parameters involved. This article is concerned with DCC modeling for multivariate GARCH processes in comparison with CCC specification. Various multivariate financial time series are analysed to illustrate possible advantages of DCC over CCC modeling.