• 대한족부족관절학회지
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• 제6권1호
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• pp.66-72
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• 2002

Purpose: To evaluate the overall results and its major affecting factors(athlete/associated injury) of modified Brostrom procedure for chronic ankle lateral instability. Materials and Methods: Fifty-one patients (51 ankles) with chronic ankle lateral instability were sub-grouped athletes and non-athletes and again sub-grouped with associated injury and without associated injury. Associated injuries were osteochondral defect(6), peroneal tendon abnormality(10), os subfibularae(4), os subtibialae(4), anterior impingement(5) and loose body(2). The overall surgical results were evaluated and also see whether or not athletes and associated injury affect the result. Result: Of the 51 operations performed, there were 39 excellent, 8 good and 4 fair as a whole. Of the 24 athletes operated, there were 19 excellent, 3 good, and 2 fair. Among the 27 non-athletes, there were 20 excellent, 5 good and 2 fair results. The average time to ordinary life in the non-athlete group was 2.5 months and average time to sports activity in the athlete was 4.5 months postoperatively. Those who didn't have any associated injury had all excellent result, on the contrary, those who had associated injuries, 14 excellent, 8 good and 4 fair results. All the fair results were associated with osteochondral lesion of talus. Whether or not the patient is athlete does not affect the surgical results, but whether or not there were associated injuries does affect the surgical results. Conclusion: Modified Brostrom procedure for chronic ankle lateral instability itself is an excellent to good operation. This procedure can be used in athletic populations who need high demand of sports activity. But chronic ankle lateral instability with associated injury group showed variable, less satisfactory results than those without associated injury. Careful preoperative and intraoperative examination should be done to find out the associated injury with chronic ankle lateral instability.

• Journal of Periodontal and Implant Science
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• 제33권1호
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• pp.13-26
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• 2003

Periodontal regeneration therapy with bone-substituting materials has gained favorable clinical efficacy by enhancing osseous regeneration in periodontal bony defect. As bone-substituting materials, bone powder, calcium phosphate ceramic, modified forms of hydroxyapatite, and hard tissue replacement polymer have demonstrated their periodontal bony regenerative potency. Bone-substituting materials should fulfill several requirements such as biocompatibility, osteogenecity, malleability, biodegradability. The purpose of this study was to investigate biocompatibility, osteo-conduction capacity and biodegradability of $Na_2O$, $K_2O$ added calcium metaphosphate(CMP). Beta CMP was obtained by thermal treatment of anhydrous $Ca_2(H_2PO_4)_2$. $Na_2O$ and $K_2O$ were added to CMP. The change of weight of pure CMP, $Na_2O$-CMP, and $K_2O$-CMP in Tris-buffer solution and simulated body fluid for 30 days was measured. Twenty four Newzealand white rabbits were used in negative control, positive control(Bio-Oss), pure CMP group, 5% $Na_2$-CMP group, 10% $Na_2O$-CMP goup, and 5% $K_2O$-CMP group. In each group, graft materials were placed in right and left parietal bone defects(diameter 10mm) of rabbit. The animals were sacrificed at 3 months and 6 months after implantation of the graft materials. Degree of biodegradability of $K_2O$ or $Na_2O$ added CMP was greater than that of pure CMP in experimental condition. All experimental sites were healed with no clinical evidence of inflammatory response to all CMP implants. Histologic observations revealed that all CMP grafts were very biocompatible and osseous conductive, and that in $K_2O$-CMP or $Na_2O$-CMP implanted sites, there was biodegradable pattern, and that in site of new bone formation, there was no significant difference between all CMP group and DPBB(Bio-Oss) group. From this result, it was suggested that all experimental CMP group graft materials were able to use as an available bone substitution.

• Journal of Periodontal and Implant Science
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• 제39권sup2호
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• pp.213-222
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• 2009

Purpose: Recently, interest in chitosan has increased due to its excellent biological properties such as biocompatibility, antibacterial effect, and rapid healing capacity. On the other hand, hydroxyapatite is used as a bone substitute in the fields of orthopedics and dentistry. The hydroxyapatite-chitosan (HA-CS) complex containing hydroxyapatite nanoparticles was developed for synergy of both biomaterials. The objective of this study was to evaluate the effect of hydroxyapatite (HA)-chitosan (CS) membrane on bone regeneration in the rat calvarial defect. Methods: Eight-millimeter critical-sized calvarial defects were created in 70 male Sprague-Dawley rats. The animals were divided into 7 groups of 10 animals and received either 1) chitosan (CS) 100% membrane, 2) hydroxyapatite (HA) 30%/CS 70% membrane, 3) HA 30%/CS 70%, pressed membrane, 4) HA 40%/CS 60% membrane, 5) HA 50%/CS 50% membrane, 6) HA 50%/CS 50%, pressed membrane, or 7) a sham . surgery control. The amount of newly formed bone from the surface of the rat calvarial defects was measured using histomorphometry, following 2- or 8- week healing intervals. Results: Surgical implantation of the HA - CS membrane resulted in enhanced local bone formation at both 2 and 8 weeks compared to the control group. The HA - CS membrane would be significantly more effective than the chitosan membrane in early bone formation. Conclusions: Concerning the advantages of biomaterials, the HA-CS membrane would be an effective biomaterial for regeneration of periodontal bone. Further studies will be required to improve the mechanical properties to develop a more rigid scaffold for the HA-CS membrane.

• Journal of Periodontal and Implant Science
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• 제48권3호
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• pp.136-151
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• 2018

Purpose: The decontamination procedure is a challenging aspect of surgical regenerative therapy (SRT) of peri-implantitis that affects its success. The purpose of the present study was to determine the impact of additional topical gaseous ozone therapy on the decontamination of implant surfaces in SRT of peri-implantitis. Methods: A total of 41 patients (22 males, 19 females; mean age, $53.55{\pm}8.98years$) with moderate or advanced peri-implantitis were randomly allocated to the test group (ozone group) with the use of sterile saline with additional ozone therapy or the control group with sterile saline alone for decontamination of the implant surfaces in SRT of peri-implantitis. Clinical and radiographic outcomes were evaluated over a period of 12 months. Results: At the 12-month follow-up, the plaque and gingival index values were significantly better in the ozone group (P<0.05). Probing depth decreased from $6.27{\pm}1.42mm$ and $5.73{\pm}1.11mm$ at baseline to $2.75{\pm}0.7mm$ and $3.34{\pm}0.85mm$ at the end of the 12-month observation period in the ozone and control groups, respectively. Similarly, the clinical attachment level values changed from $6.39{\pm}1.23mm$ and $5.89{\pm}1.23mm$ at baseline to $3.23{\pm}1.24mm$ and $3.91{\pm}1.36mm$ at the 12-month follow-up in the ozone and control groups, respectively. According to the radiographic evidence, the defect fill between baseline and 12 months postoperatively was $2.32{\pm}1.28mm$ in the ozone group and $1.17{\pm}0.77mm$ in the control group, which was a statistically significant between-group difference (P<0.05). Conclusions: Implant surface decontamination with the additional use of ozone therapy in SRT of peri-implantitis showed clinically and radiographically significant. Trial registry at ClinicalTrials.gov, NCT03018795.

• 대한치과보철학회지
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• 제55권4호
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• pp.410-418
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• 2017

법랑질 형성 부전증은 유전적인 결함으로 인해 구조적으로 약한 법랑질이 형성되는 질환이다. 이들 환자들은 이른 나이부터 진행되는 법랑질 마모에 의한 시린 증상과 비심미적인 치아를 주소로 치과에 내원하게 되며, 성장기 이후에는 전악 보철 수복을 통해 치아의 기능성과 심미성을 회복해 주게 된다. 법랑질 형성 부전증 환자에서 보여지는 전치부 개방 교합은, 구치의 교합면 마모 및 보상성 맹출에 의한 수직적 수복 공간 문제와 결부되어 보철 치료를 어렵게 하는 요인이 된다. 따라서 전치 길이의 결정 및 교합 고경의 거상 여부, 전방유도의 설정은 신중히 결정되어야 한다. 근래에는 Computer aided design-computer aided manufacturing (CAD/CAM) 기술을 이용하여 진단 및 최종 수복으로의 이행이 용이해 졌다. 본 증례에서는 전치부 개방교합을 가지고 있는 법랑질 형성 부전증 환자에서, CAD/CAM을 이용한 전악 수복을 시행한 후, 양호한 경과를 보이고 있기에 이를 보고하고자 한다.

• 구강회복응용과학지
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• 제28권3호
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• pp.301-307
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• 2012

50세 여자 환자와 남자 환자가 파노라마 방사선사진에서 우연히 발견된 무증상의 하악 구치부의 방사선투과성 병소로 인해 의뢰되었다. 임상검사에서 특이할 만한 소견은 발견되지 않았다. 파노라마 방사선사진에서 각각 우측과 좌측 하악 구치부에서 경계가 비교적 명확하며, 과골성 변연을 수반하지 않는 원형의 방사선투과성 병소가 관찰되었다. 병소 내부는 다방성의 양상이었으며, 또한 병소 부위를 주행하는 하악관의 불연속성 소견이 관찰되었다. 이에 양성 종양을 배제하기 위해서 조영증강 전산화단층사진을 촬영하였다. 전산화단층사진의 축상면에서 불규칙한 경계를 가지는 명확한 설측 함요부가 관찰되었으며, 내부는 지방 및 일부 악하선 조직으로 채워져 있었으나 다른 질환을 의심할 만한 연조직 종괴는 관찰되지 않았다. 최종적으로 비전형적 형태의 발육성 타액선 골결손으로 진단하였으며, 이 중 한 증례에서, 4개월 후의 재검사시 촬영한 파노라마 방사선사진에서 뚜렷한 변화가 관찰되지 않았다. 본 증례들과 같은 비전형적 발육성 타액선 골결손을 다른 질환과 감별하기 위해서는 단면 및 내부 구조물에 대한 보다 정확한 평가가 이루어져야 하므로 일반방사선사진뿐만 아니라 전산화단층영상 또는 자기공명영상이 추가적으로 필요하리라 생각된다.

• 수면정신생리
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• 제1권1호
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• pp.87-98
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• 1994

연구배경 : 정신분열증 환자들이 정보처리 과정의 문제가 있을 것이라는 가설을 지지해 주는 사건관련유발 전위인 P3의 이상을 보고하는 연구들이 있어 저자들은 정신분열증 환자들에게 청각사건관련유발 전위를 실시하여 P3의 이상을 확인하고자 하였다. 또한, 음성 및 양성 정신분열증환자에 P3의 차이가 있는지 비교하였으며, 가족력이나 전기충격경련요법, 밖에 임상양상과 P3와의 연관성을 알아보기 위하여 본 연구를 실시하였다. 방법 : DSM-III-R 진단기준에 맞는 정신분열증 환자 54명 (남자 31, 여자 23) 과 그 대조군 75 명 (남자 33, 여자 42) 을 대상으로 oddball paradigm 을 이용한 사건관련유발전위를 실시하여 P3의 잠복기와 진폭을 측정하였으며, 정신분열증의 인지기능이상을 알아볼 수 있는 프랑크푸르트 임상검사를 같이 실시하였다. 결과 : 정신분열증 환자의 P3 잠복기는 그 대조군에 비해 의미 있게 지연되어 있었으며, 또한 모든 진폭도 대조군에 비해 의미 있게 감소되어 있었다. 정신분열증 환자군에서 프랑크푸르트 임상검사의 10가지 임상증상 모두에서 통계적으로 유의하게 높은 점수를 보였다. PANSS의 종합점수에 따라 음성과 양성으로 나누어 비교한 결과, P3의 잠복기 및 진폭에서 의미 있는 차이가 발견되지 않았다. 또한, 정신과질환의 가족력의 유무에 따라, 전기 충격경련요법 유무에 따라 비교한 결과 의미 있는 차이를 발견할 수 없었다. 환자군에서 프랑크푸르트 임상검사의 임상증상, 그밖에 임상특성과 P3의 잠복기와 진폭 사이에 연관성을 발견할 수 없었다. 결론 : 본 연구의 결과로 정신분열증 환자들에서 선택적 주의집중 과정의 이상이 있을 것이고 추측할 수 있었으며, 임상양상이나 가족력 유무와 P3사이에 연관성이 없다는 것을 시사해 주었다.

• Tuberculosis and Respiratory Diseases
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• 제54권2호
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• pp.230-235
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• 2003

저자들은 폐색전증 의심하에 항응고제를 포함한 약물치료를 시행하였으나 임상증상의 호전이 없는 환자에서, 흉부 전산화단층촬영과 흉부 자기공명영상촬영을 통해 색전을 동반한 혈관의 종물을 발견한 후 수술적 제거로 진단한 원발성 폐동맥 육종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.9-12
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• 2008

반강접합은 핀접합의 단점을 보완하고 강접합의 장점을 수용할 수 있는 중간 형태이다. 현재 국내에서 핀접합에 대한 연구는 활성화 되어있으나 반강접합에 대한 연구는 많지 않기 때문에 본 연구에서는 3가지 형태의 실험체를 제작하여 성능을 입증하려 했다. 실험체는 강접합 HI-R, 반강접합 HI-S, 핀접합 HI-P등 총 3개이다. 실험결과 HI-R은 접합부 전단파괴, HI-S는 고정단 상부 휨파괴, HI-P는 경사계단 슬래브 하부 휨파괴로 나타났고 최대내력은 각각 51.74, 51.4, 24.63kN으로 측정되었고, 강성은 1.58, 1.19, 0.37을 나타냈다. 항복강도는 각각 44.5, 47.3, 24kN을 보유하고, 연성비는 3.31, 2.32, 1.54로 나타냈고, 사용하중 작용 시의 처짐은 KBC기준에 의거하여 HI-P실험체가 기준을 초과하는 것으로 나타났다. 철근 변형률분포로 보아 HI-S는 초기에 HI-R과 유사한 거동을 보이나 항복이후 접합부 내부요소들의 응력분담으로 핀접합보다는 우수한 성능을 보유한 반강접 접합부로 판단할 수 있었다.

• 대한두개안면성형외과학회지
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• 제17권3호
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• pp.128-134
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• 2016

Background: Blowout fracture is one of the most common facial fractures, and patients usually present with accompanying ocular complications. Many studies have looked into the frequency of persistent ocular symptoms, but there is no study on assault patients and related ocular symptoms. We evaluated the incidence of residual ocular symptoms in blowout fractures between assaulted and non-assaulted patients, and sought to identify any connection among the degree of enophthalmos, defect size, and assault-related injury. Methods: A retrospective review was performed for any patient who sustained a unilateral blowout fracture between January 2010 to December 2014. The collected data included information such as age, gender, etiology, and clinical ocular symptoms as examined by an ophthalmologist. This data was analyzed between patients who were injured through physical altercation and patients who were injured through other means. Results: The review identified a total of 182 patients. Out of these, 74 patients (40.7%) have been struck by a fist, whereas 108 patients (59.3%) have sustained non-assault related injuries. The average age was 36.1 years, and there was a male predominance in both groups (70 patients [94.6%] in the assaulted group and 87 patients [80.6%] in the non-assault group). Diplopia and enophthalmos were more frequent in patients with assault history than in non-assaulted patients (p<0.05). Preoperatively, 25 patients (33.8%) with assault history showed diplopia, whereas 20 patients (18.5%) showed diplopia in the non-assaulted group (p<0.05). Preoperative enophthalmos was present in 34 patients (45.9%) with assault history, whereas 31 patients (28.7%) showed enophthalmos in the non-assaulted group (p<0.05). Conclusion: Patients with an assault history due to a fist blow experienced preoperative symptoms more frequently than did patients with non-assault-related trauma history. Preoperative diplopia and enophthalmos occurred at a higher rate for patients who were assaulted. Surgeons should take into account such characteristics in the management of assaulted patients.