• Title/Summary/Keyword: Dermatology

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Fungal Genomics in Dermatology

  • Lee, Young Bok;Lee, Soo Young;Seo, Ji Min;Kang, Min Ji;Yu, Dong Soo
    • Journal of Mycology and Infection
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    • v.24 no.2
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    • pp.37-44
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    • 2019

  • To date, hundreds of fungal genomes have been sequenced, and many more are underway. Recently developed cutting-edge techniques generate very large amounts of data, and the field of fungal genomics in dermatology has consequently evolved substantially. Methodological improvements have broadened the scope of large-scale ecological studies in dermatology, including biodiversity assessments and genomic identification of fungi. Here, we aimed to provide a brief introduction to bioinformatic approaches to fungal genomics in the field of dermatology. We described the history and basic concepts of fungal genomics and presented sequencing-based techniques for fungal identification, including a list of the revised taxa of dermatophytes, as determined by current phylogenetic analysis. Finally, we discussed the emerging trends in fungal genomics in dermatology, such as next-generation sequencing.

  • https://doi.org/10.17966/JMI.2019.24.2.37 인용

Mycosis Fungoides Responsive to Oral Alitretinoin and Ultraviolet B Phototherapy: A Case Report

  • Han, Song Hee;Hong, Ji Youn;Hong, Joo Ran;Hur, Min Seok;Youn, Hae Jeong;Lee, Yang Won;Choe, Yong Beom;Ahn, Kyu Joong
    • Korean journal of dermatology
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    • v.56 no.10
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    • pp.636-639
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    • 2018

  • Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. Patients with early stage disease usually respond well to conventional therapies, with a relatively favorable prognosis. However, a few patients are refractory to treatment and need alternative strategies, even at the patch and plaque stages. We report the case of a middle-aged woman with long-standing and refractory mycosis fungoides that responded to combination therapy with the 308-nm excimer laser and oral alitretinoin.

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