• Title/Summary/Keyword: Diabetes Mellitus

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DMBase: An Integrated Genetic Information Resource for Diabetes Mellitus

  • Lee, Sun-Young;Park, Young-Kyu;Kim, Jae-Heup;Kim, Young-Joo
    • Interdisciplinary Bio Central
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    • v.3 no.2
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    • pp.6.1-6.3
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    • 2011
  • Diabetes Mellitus (DM), often simply referred to as diabetes, has developed into a major health concern affecting more than 200 million people worldwide with approximately 4 million deaths per year attributed to the presence of the disease. Diabetes mellitus is categorized as Type 1 and Type 2, where Type 1 diabetes represents a lack of insulin production, and Type 2 diabetes is characterized by a relative lack of insulin receptor (i.e., decreased sensitivity to the effect of insulin) and cased by a complex interplay between genetic factors and environmental factors. Up to date, various studies on the pathology and mechanism in terms of genetic experiments have been conducted and approximately hundreds of genes were reported as diabetes mellitus associated genes. At this point, to support studies on the cause and mechanism of diabetes mellitus, an efficient database system to provide genetic variants related to diabetes mellitus is needed. DMBase is an integrated web-based genetic information resource for diabetes mellitus designed to service genomic variants, genes, and secondary information derived for diabetes mellitus genetics researchers. The current version of DMBase documents 754 genes with 3056 genetic variants and 66 pathways. It provides many effective search interfaces for retrieving diabetes mellitus and genetic information. A web interface for the DMBase is freely available at http://sysbio.kribb.re.kr/dmBase.

Factors Related to Self Management in Middle Aged and Elderly with Diabetes Mellitus (중년기와 노년기 당뇨병 환자의 자가관리 관련요인)

  • Moon, Mi-Young;Kim, Myung-Ae
    • Journal of Korean Public Health Nursing
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    • v.19 no.2
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    • pp.261-273
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    • 2005
  • Purpose: The purpose of this study was to explore the self management and related factors that affect the self management of diabetes between the middle aged and elderly groups. Method: This study was based by the conceptual framework of Cox's interaction model of client health behavior. The subjects were two groups; the middle aged group, 80 and the elderly group, 85 who were diabetes mellitus patients. Result: In the middle aged group, gender, education and social support were significantly correlated with self-management of diabetes mellitus. In the elderly group, gender, education, social support and the duration of diagnosis were significantly correlated with self-management of diabetes mellitus. In too middle aged group, the intrinsic motivation of diabetes mellitus patients and their understanding of diabetes were significantly correlated with self-management of diabetes mellitus. Understanding of diabetes and self perception were significantly correlated with self-management in middle aged group. In the elderly group, intrinsic motivation, understanding of diabetes and the attitude of the patients were significantly correlated with self-management Conclusion: In the middle aged group, maintaining a positive attitude of diabetes, reducing stress and continuous social support were important for improving self-management of diabetes mellitus. In the elderly group, enhancing their knowledge of diabetes, and maintaining continuous social support were important to improve self-management of diabetes mellitus.

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Prevalence and Risk Factors for Diabetes Mellitus and Impaired Fasting Glucose of Adults (30-69세 성인의 공복혈당장애와 당뇨병의 유병률과 위험인자 분석)

  • 김희승;노유자;김남초;유양숙;용진선;오정아
    • Journal of Korean Academy of Nursing
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    • v.30 no.6
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    • pp.1479-1487
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    • 2000
  • This study was conducted to draw out prevalence and the risk factors of diabetes mellitus and impaired fasting glucose for adults,(age 30-69). The subjects were 2096 adults, who had regular health examinations between January and December of 1999 at K Hospital in Seoul. The data was analyzed using chi-square test, unpaired t-test and logistic regression. Diabetes Mellitus and impaired fasting glucose were diagnosed by ADA (American Diabetes Association, 1997) criteria. The results were as follows: 1. Mens' prevalence of Diabetes Mellitus was 7.9% and womens' prevalence of Diabetes Mellitus was 3.8%. Mens' prevalence of impaired fasting glucose was 10.4% and womens' prevalence of impaired fasting glucose was 6.5%. Prevalences of Diabetes Mellitus and impaired fasting glucose increased with age. 2. Prevalence of Diabetes Mellitus and impaired fasting glucose of obese subjects (relative body weight>=162) was higher than that of overweight subjects (110<=relative body weight<=119) in men and women. 3. The diagnoses of Diabetes Mellitus and impaired fasting glucose increased with systolic blood pressure and triglyceride. 4. Significant factors associated with diabetes in the logistic regression best gut model were age, relative body weight, systolic blood pressure, triglyceride in men, and systolic blood pressure in women. In conclusion, as age, weight, systolic blood pressure and triglyceride get higher, Diabetes Mellitus and impaired fasting glucose prevalence also increases, porportionally.

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Comparision of Body Image between DM Patients who used Insulin Pump and didn't use Insulin Pump (인슐린 펌프 착용 유무에 따른 당뇨병환자의 신체상 비교)

  • Lee, Myung-Hwa;Woo, Kyung-Mi;Kim, Kyung-Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.4 no.2
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    • pp.251-264
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    • 2001
  • The purpose of study was to compare body image between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy. The study design was comparative survey study the subjects were 60 diabetes mellitus patients who used insulin pump therapy and 60 diabetes mellitus patients who didn't use insulin pump therapy at B hospital in Busan. The data were collected from 15th April to 20th August, 1998. The instrument used for this study were Osgood's body image scale. The collected data were analyzed frequency, percentage, $X^2$-test, mean, standard deviation, t-test, ANOVA, Scheffe test. The results were as follows 1. Demographical characteristics between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy were no significant difference. 2. Characteristics related disease between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy were significant difference in paticipation of D.M. meeting, no of paticipation of D.M. meeting. 3. Body inmage score of diabetes mellitus patients was $69.08{\pm}18.13$. In body image, diabetes mellitus patients who used insulin pump therapy were higher than that didn't use insulin pump therapy(t=1.964, P<.05) 4. In body image's each item, common-strange item, noble-humble item, competent-incompetent item, light-heavy item, diabetes mellitus patients who used insulin pump therapy were higher than diabetes mellitus patients who didn't use insulin pump therapy(P<.05). 5. In body image according to economic status, marital status, occupational status were significantly difference. 6. In body image according to causes of regular hospital visiting, paticipation of diabetes mellitus class were significantly difference. In conclusion, diabetes mellitus patients who used insulin pump therapy were more positive than diabetes mellitus patients who didn't use insulin pump therapy.

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Comparision of Body Image between DM patients who used Insulin Pump and didn't use Insulin Pump (인슐린 펌프 착용 유무에 따른 당뇨병환자의 신체상 비교)

  • Lee, Myung-Hwa;Woo, Kyung-Mi;Kim, Kyung-Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.4 no.1
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    • pp.105-118
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    • 2001
  • The purpose of study was to compare body image between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy. The study design was comparative survey study the subjects were 60 diabetes mellitus patients who used insulin pump therapy and 60 diabetes mellitus patients who didn't use insulin pump therapy at B hospital in Busan The data were collected from 15th April to 20th August, 1998. The instrument used for this study were Osgood's body image scale. The collected data were analyzed frequency, percentage, $X^2$-test, mean, standard deviation, t-test, ANOVA, Scheffe test. The results were as follows 1. Demographical characteristics between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy were no significant difference. 2. Characteristics related disease between diabetes mellitus patients who used insulin pump therapy and didn't use insulin pump therapy were significant difference in paticipation of D.M. meeting, no of paticipation of D.M. meeting. 3. Body inmage score of diabetes mellitus patients was $69.08{\pm}18.13$. In body image, diabetes mellitus patients who used insulin pump therapy were higher than that didn't use insulin pump therapy(t=1.964, P<.05) 4. In body image's each item, common-strange item, noble-humble item, competent-incompetent item, light-heavy item, diabetes mellitus patients who used insulin pump therapy were higher than diabetes mellitus patients who didn't use insulin pump therapy(P<.05) 5. In body image according to economic status, marital status, occupational status were significantly difference. 6. In body image according to causes of regular hospital visiting, paticipation of diabetes mellitus class were significantly difference. In conclusion, diabetes mellitus patients who used insulin pump therapy were more positive than diabetes mellitus patients who didn't use insulin pump therapy.

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A Case Report of Paralytic Patient Associated with Diabetes Mellitus (당뇨를 동반한 뇌경색 환자의 천화산가미방 치험 1례)

  • Kim, Byoung-Woo
    • Journal of Pharmacopuncture
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    • v.12 no.3
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    • pp.97-102
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    • 2009
  • Objectives : This report aimed to study of paralytic patient associated with Diabetes Mellitus. Methods : Diabetes Mellitus has one of the highest death rate, because of it induces various complications. Especially paralytic patients who associated with diabetes mellitus are slow in recovery and easy to induce many complications. So control of the diabetes mellitus is the most important thing to treatment. We observed and treated with Cheunhwasangamibang and acupunture. Results : The paralytic patient with Diabetes Mellitus was treatment with Cheunhwasangamibang and improvement was seen. Conclusions : Results in this case support a role for Cheunhwasangamibang in controlling Diabetes Mellitus.

A Study on the Polymorphisms in Parotid Salivary Proteins of the Patients with Diabetes Millitus (당뇨병 환자의 이하선 타액내 단백질의 다형현상에 대한 연구)

  • Jong-Mo Ahn;Chang-Lyuk Yoon
    • Journal of Oral Medicine and Pain
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    • v.17 no.2
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    • pp.99-108
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    • 1992
  • The purpose of this study was to evaluate the polymorphosms in parotid salivary proteins of the patients with diabetes mellitus. Saliva from the parotid glands was collected from 94 healthy Korean adults who were live in Kwang-ju and from 33 diabetes mellitus patients who had more than 140mg/dl of fastingblood sugar for one week. Diabetes mellitus patient group was subdivided to insulin dependent diatetes mellitus (IDDM) and non-insulin dependent diabetes mellitus (NIDDM). In the saliva collected from the parotid glands, parotid acidic protein(Pa), proline-rich protein(Pr) and double band protein(Db) were analyzed to evaluate the distribution of phenotype using alkaline slab polyacrylamide gel electrophoresis. The results were as follows : 1. The parotid acidic protein (Pa) was found more frequently in the diabetes mellitus patient group than in the control group, but the difference was not statistically significant. 2. The Pr(1-2) type was found more frequently in the control group, but the Pr(1-1) and Pr(2-2) type were found more freqnently in the diabetes mellitus patient group and the difference of phenotypic distribution was statistically significant between the two groups. (p<0.05) 3. The parotid acidic protein(Pa) and Pr(1-2) type were found more frequently in the noninsulin dependent diabetes mellitus (NIDDM) patients than in the insulin dependent diabetes mellitus patients, though the difference was not statistically significant.

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Knowledge and Diffusion of Knowledge for Nursing Care of Patients with Diabetes Mellitus among Clinical Nurses (우리나라 임상간호사의 당뇨병 지식 및 지식 확산도 조사연구)

  • Hong, Myeong Hee;Yoo, Joo Wha;Kim, Soon Ai;Lee, Jeong Rim;Roh, Na Ri;Park, Jeong Eun;Gu, Mee Ock
    • Journal of Korean Clinical Nursing Research
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    • v.15 no.3
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    • pp.61-74
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    • 2009
  • Purpose: In order to increase the quality of nursing care for patients with diabetes mellitus, it is important for clinical nurses to accept changes in diabetes knowledge and correct their approach immediately. This approach will also contribute to effective nursing practice. Methods: The study was designed to investigate the level of knowledge and diffusion of knowledge for nursing care of patients with diabetes mellitus among clinical nurses. It was conducted with nurses from 29 general hospitals in Korea from November 3 to December 5, 2008. The questionnaire consisted of 129 items and it was sent to the participants by mail. Of the 1,060 questionnaires returned, only 930 were valid for use in the statistical analysis. Results: 1) The average score for clinical nurses' knowledge of diabetes mellitus was 0.67 out of 1.0. 2) The level of persuasion of knowledge for nursing care of patients with diabetes mellitus averaged 0.64 out of 1.0 3) The level of practical application of knowledge for nursing care of patients with diabetes mellitus averaged 1.05 out of 2.0, indicating that they applied their knowledge 'sometimes'. 4) The level of diffusion of knowledge for nursing care of patients with diabetes mellitus was 2.37 out of 4.0 and level was estimated as the stage of 'persuasion'. 5) There were significant differences in nursing knowledge of diabetes mellitus, according to experience in practical education for diabetes mellitus. Conclusion: The results indicate that nurses with a lower level of knowledge of diabetes mellitus have a lower level of persuasion of knowledge for nursing care of patients with diabetes mellitus and lower practical application. To improve the level of nurses' knowledge of diabetes mellitus, practical training programs are needed for areas in which knowledge level is low, such as 'diagnosis and management of diabetes mellitus', 'oral diabetes medication', and 'glucose control in special conditions'.

Need for Diabetes Prevention Study (당뇨병 예방연구의 필요성)

  • Jeon, Ja Young;Kim, Dae Jung
    • The Journal of Korean Diabetes
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    • v.16 no.3
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    • pp.161-167
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    • 2015
  • In Korea, diabetes mellitus, which causes micro and macrovascular complications, has been rapidly increasing during recent decades and has become a leading cause of disability-adjusted life years. The prevalence of diabetes mellitus was 12.4% in 2011 and that of prediabetes, a condition of high risk for developing diabetes mellitus, is 1.5- to 3-fold greater than that of diabetes. The diabetes prevention programs in other countries were shown to reduce or delay progression from prediabetes to diabetes mellitus. However, these results are not applicable to Korean people because of genetic and environmental differences. Therefore, we need to plan and perform a diabetes prevention study in Korean. Based on these results, we should design intervention tools for a Korean diabetes prevention program. We can consider several preventive interventions with lifestyle modification suitable for Korean people and pharmacologic treatments such as metformin or alpha-glucosidase inhibitor.

Relationship between Body image and Depression of Diabetes Mellitus Patients (당뇨병환자의 신체상과 우울과의 관계)

  • Lee, Myung-Hwa;Song, Myung-Sook
    • The Korean Journal of Rehabilitation Nursing
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    • v.5 no.1
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    • pp.49-59
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    • 2002
  • The purpose of study was to identify relationship between body image and depression of diabetes mellitus patients. The subjects of study were 120 diabetes mellitus patients who were B hospital in Pusan. Data were collected from 15th April to 20th August, 1998. The instrument used for this study were Osgood's body image scale and Zung's depression scale. The collected data were analyzed frequency, percentage, mean, standard deviation, t-test, ANOVA, Scheffe test, Pearson's correlation coefficients. The results were as follows: 1. The mean score of body image was $68.91{\pm}18.04$, and the mean score of depression was $56.18{\pm}11.58$. 2. The score of body image according to marital status(t=-2.434, p=.016), economic status (F=6.252, p=.001), reason of different regular hospital visiting(F=3.017, p=.014), treatment method of diabetes mellitus(F=3.048, p=.013) were significantly difference. ere significantly difference. 3. The score of depression according to sex(t=2.353, p=.020), occupational status(F=4.657, p=.002), marital status(t=-2.325, p=.022), economic status(F=5.536, p=.001), regular hospital visiting(t=2.081, p=.040), reason of different regular hospital visiting(F=3.352, p=.007), treatment method of diabetes mellitus(F=3.102, p=.012), paticipation of diabetes mellitus(t=3.726, p=.000), paticipation of diabetes mellitus visiting(F=4.819, p=.003) were significantly difference. 5. Body image and depression was a significant negative correlation(r=-.679. p=.000). Conclusion: From this study, a relationship between body image and depression inpatients with diabetes mellitus was idetified. Therefore, nursing intervention are needed to promote body image and depression in patients with diabetes mellitus.

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